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1. Full Text Synthesis of N‐Heteroaromatic Compounds through Cyclocarbonylative Sonogashira Reactions
by Aronica, Laura Antonella and Albano, Gianluigi and Giannotti, Luca and Meucci, Elisa
European Journal of Organic Chemistry, ISSN 1434-193X, 02/2017, Volume 2017, Issue 5, pp. 955 - 963
A protocol based on cyclocarbonylative Sonogashira reactions has been developed for the synthesis of nitrogen‐containing heterocycles. The process is carried... 
Carbonylation | Synthetic methods | Cyclization | Nitrogen heterocycles | Cross‐coupling | Homogeneous catalysis | Cross-coupling | FORMIC-ACID | Cross coupling | ASYMMETRIC-SYNTHESIS | CARBONYLATION REACTIONS | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | ALKYNES | ISOINDOLINE | HETEROCYCLES | INDOLE ALKALOIDS | CO SOURCE | Chemotherapy | Cancer
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2. Full Text Cyclocarbonylative Sonogashira Reactions of 1‐Ethynylbenzyl Alcohols: Synthesis of 1‐Carbonylmethylene‐1,3‐Dihydroisobenzofurans
by Aronica, Laura Antonella and Giannotti, Luca and Tuci, Giulia and Zinna, Francesco
European Journal of Organic Chemistry, ISSN 1434-193X, 08/2015, Volume 2015, Issue 22, pp. 4944 - 4949
In this work, we present a carbonylative Sonogashira reaction of o‐ethynyl benzyl alcohols and aryl iodides, followed by a cyclization process to selectively... 
Carbonylation | Synthetic methods | Cyclisation | Oxygen ­heterocycles | Cross‐coupling | Homogeneous catalysis | Cross-coupling | Oxygen heterocycles | PEPTIDE DEFORMYLASE | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | CARBON TRIPLE BOND | ARYL BROMIDES | 2-ALKYNYLBENZYL ALCOHOLS | CATALYZED OXIDATIVE CARBONYLATION | ACID-CHLORIDES | ASPERGILLUS-FLAVIPES | COUPLING REACTION | BIOLOGICAL EVALUATION
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3. Full Text Severe Plasmodium falciparum malaria in the intensive care unit: A 6-year experience in Milano, Italy
by Antinori, Spinello and Corona, Alberto and Castelli, Antonio and Rech, Roberto and Borghi, Beatrice and Giannotti, Claudia and Colombo, Riccardo and Fossali, Tommaso and Ballone, Elisabetta and Minari, Caterina and Perotti, Andrea and Bergomi, Paola and Galimberti, Laura and Milazzo, Laura and Ricaboni, Davide and Scorza, Daniele and Grande, Romualdo and Genderini, Francesco and Ieri, Marco and Raimondi, Ferdinando and Catena, Emanuele and Galli, Massimo and Corbellino, Mario
Travel Medicine and Infectious Disease, ISSN 1477-8939, 2017, Volume 17, pp. 43 - 49
Abstract Background Severe imported Plasmodium falciparum malaria is a potentially life-threatening disease with a reported mortality rate of 4–10% when... 
Infectious Disease | Severe malaria | Plasmodium falciparum | Imported malaria | Quinine | Intensive care unit | INFECTIOUS DISEASES | MULTICENTER | SCORE | AFRICAN MIGRANTS | RETROSPECTIVE COHORT | ADULTS | SEVERE IMPORTED MALARIA | BLOOD-CELL EXCHANGE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INTRAVENOUS ARTESUNATE | TRAVELERS | DISEASE | Malaria, Falciparum - drug therapy | Intensive Care Units | Humans | Middle Aged | Male | Antimalarials - therapeutic use | Quinine - therapeutic use | Travel | Malaria, Falciparum - mortality | Malaria, Falciparum - diagnosis | Malaria, Falciparum - epidemiology | Adult | Female | Italy - epidemiology | Retrospective Studies | Malaria | Mortality | Anopheles | Health care | Coma | Intensive care | Transfusion | Disease | Methodology | Erythrocytes | Blood | Tropical diseases | Risks | Medical referrals | Public health | Age | Vector-borne diseases | Evaluation | Human diseases | Anemia | Prediction | Management | Patients | Hospitals | Organizations | Ventilation | Fatalities | Adults
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4. Full Text Quercetin inhibition of SREBPs and ChREBP expression results in reduced cholesterol and fatty acid synthesis in C6 glioma cells
by Damiano, Fabrizio and Giannotti, Laura and Gnoni, Antonio and Gnoni, Gabriele V and Siculella, Luisa
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 12/2019, Volume 117, p. 105618
Quercetin (Que), a widely distributed flavonoid in the human diet, exerts neuroprotective action because of its property to antagonize oxidative stress. Here,... 
Cholesterol and fatty acid synthesis | ChREBP and SREBPs | 3-Hydroxy-3-methyl-glutaryl-CoA reductase | C6 glioma cells | Acetyl-CoA carboxylase 1 | Quercetin
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5. Full Text Vitamin D Treatment Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in an Animal Model of Parkinson’s Disease, Shifting M1 to M2 Microglia Responses
by Calvello, Rosa and Cianciulli, Antonia and Nicolardi, Giuseppe and De Nuccio, Francesco and Giannotti, Laura and Salvatore, Rosaria and Porro, Chiara and Trotta, Teresa and Panaro, Maria Antonietta and Lofrumento, Dario Domenico
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 06/2017, Volume 12, Issue 2, pp. 327 - 339
Microglia-mediated neuroinflammation has been described as a common hallmark of Parkinson’s disease (PD) and is believed to further exacerbate the progressive... 
Neuroinflammation | MPTP | Vitamin D | Parkinson’s disease | Microglia | Cytokines | Neurodegeneration | Rodents | Parkinsons disease
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6. The italian music superdiversity
by Laura Pollacci and Riccardo Guidotti and Giulio Rossetti and Fosca Giannotti and Dino Pedreschi
Multimedia Tools and Applications, ISSN 1380-7501, 02/2019, Volume 78, Issue 3, pp. 3297 - 3319
Globalization can lead to a growing standardization of musical contents. Using a cross-service multi-level dataset we investigate the actual Italian music... 
Music | Globalization | Standardization
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7. Full Text Synthesis of 2‐Alkylideneisochromans by Cyclocarbonylative Sonogashira Reactions
by Aronica, Laura Antonella and Giannotti, Luca and Giuntini, Stefano and Caporusso, Anna Maria
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2014, Volume 2014, Issue 31, pp. 6858 - 6862
In this study we used a tandem carbonylative Sonogashira reaction/cyclisation process to construct alkylidene‐functionalized isochromans in high yields with... 
Cross‐cou­pling | Carbonylation | Synthetic methods | Cyclization | Oxygen heterocycles | Cross-coupling | HETEROCYCLES | ISOCHROMAN | CHEMISTRY, ORGANIC | DERIVATIVES | FLAVONES
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8. Full Text Cyclocarbonylative Sonogashira Reactions of 1-Ethynylbenzyl Alcohols: Synthesis of 1-Carbonylmethylene-1,3-Dihydroisobenzofurans
: Cyclocarbonylative Sonogashira Reactions
by Aronica, Laura Antonella and Giannotti, Luca and Tuci, Giulia and Zinna, Francesco
European Journal of Organic Chemistry, ISSN 1434-193X, 08/2015, Volume 2015, Issue 22, pp. 4944 - 4949
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9. Full Text The modulation of BDNF expression and signalling dissects the antidepressant from the reinforcing properties of ketamine: Effects of single infusion vs. chronic self-administration in rats
by Caffino, Lucia and Di Chio, Marzia and Giannotti, Giuseppe and Venniro, Marco and Mutti, Anna and Padovani, Laura and Cheung, David and Fumagalli, Fabio and Fumagalli, Guido F and Yew, David T and Chiamulera, Cristiano
Pharmacological Research, ISSN 1043-6618, 02/2016, Volume 104, pp. 22 - 30
Ketamine is a drug of abuse with a unique profile, which besides its inherent mechanism of action as a non-competitive antagonist of the NMDA glutamate... 
Antidepressant | Reinforcement | Ketamine | Rat | BDNF | Zif-268 | ZIF268 | C-FOS | NEUROTROPHIC FACTOR | HIPPOCAMPAL BDNF | FORCED SWIMMING TEST | NUCLEUS-ACCUMBENS | NGFI-A | MESSENGER-RNA | MEDIAL PREFRONTAL CORTEX | PHARMACOLOGY & PHARMACY | BRAIN | Signal Transduction | Reinforcement (Psychology) | Male | Rats, Sprague-Dawley | Ketamine - administration & dosage | Brain - drug effects | Brain - metabolism | Self Administration | Animals | Antidepressive Agents - administration & dosage | Antidepressive Agents - pharmacology | Brain-Derived Neurotrophic Factor - metabolism | Infusions, Intravenous | Ketamine - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Early Growth Response Protein 1 - metabolism | Antidepressants
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10. Full Text Synthesis of 2-Alkylideneisochromans by Cyclocarbonylative Sonogashira Reactions
: Synthesis of 2-Alkylideneisochromans
by Aronica, Laura Antonella and Giannotti, Luca and Giuntini, Stefano and Caporusso, Anna Maria
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2014, Volume 2014, Issue 31, pp. 6858 - 6862
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11. Full Text Broadening phenotype of adenylosuccinate lyase deficiency: A novel clinical pattern resembling neuronal ceroid lipofuscinosis
by Mastrangelo, Mario and Alfonsi, Chiara and Screpanti, Isabella and Masuelli, Laura and Tavazzi, Barbara and Mei, Davide and Giannotti, Flavia and Guerrini, Renzo and Leuzzi, Vincenzo
Molecular Genetics and Metabolism Reports, ISSN 2214-4269, 12/2019, Volume 21, p. 100502
We describe a 7-year-old boy presenting with a developmental encephalopathy, severe epilepsy, retinopathy with salt and pepper fundus, and ultrastructural skin... 
Retinopathy | Children | Drug- resistant epilepsy | Neurodegenerative disorders | Purine metabolism
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12. Full Text The Liverpool Care Pathway for cancer patients dying in hospital medical wards: A before–after cluster phase II trial of outcomes reported by family members
by Costantini, Massimo and Pellegrini, Fabio and Di Leo, Silvia and Beccaro, Monica and Rossi, Carla and Flego, Guia and Romoli, Vittoria and Giannotti, Michela and Morone, Paola and Ivaldi, Giovanni P and Cavallo, Laura and Fusco, Flavio and Higginson, Irene J
Palliative Medicine, ISSN 0269-2163, 1/2014, Volume 28, Issue 1, pp. 10 - 17
Background: Hospital is the most common place of cancer death but concerns regarding the quality of end-of-life care remain. Aim: Preliminary assessment of the... 
Liverpool Care Pathway | quality of health care | hospital | palliative care | Cancer | end-of-life care | OF-LIFE CARE | ISDOC | DEATH | VIEWS | MEDICINE, GENERAL & INTERNAL | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEALTH CARE SCIENCES & SERVICES | END | ITALIAN SURVEY | LAST 3 MONTHS | CAREGIVERS | Family - psychology | Humans | Male | Palliative Care | Terminal Care - psychology | Outcome and Process Assessment (Health Care) - methods | Advance Care Planning - standards | Neoplasms - therapy | Outcome and Process Assessment (Health Care) - standards | Hospital Units - statistics & numerical data | Female | Interviews as Topic | Terminal Care - standards | Neoplasms - mortality | Treatment Outcome | Chronic Disease - mortality | Critical Pathways | Pilot Projects | Terminal Care - statistics & numerical data | Hospital Units - standards | Advance Care Planning - statistics & numerical data | Chronic Disease - therapy | Italy | Aged | Program Evaluation | Cluster Analysis
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13. Full Text Mating system modulates degree of seed dormancy in Hypericum elodes L. (Hypericaceae)
by Carta, Angelino and Bedini, Gianni and Giannotti, Angela and Savio, Laura and Peruzzi, Lorenzo
Seed Science Research, ISSN 0960-2585, 09/2015, Volume 25, Issue 3, pp. 299 - 305
Knowledge of processes responsible for seed dormancy can improve our understanding of the evolutionary dynamics of reproductive systems. We examined the... 
dormancy degree | self-compatibility | mating system | inbreeding | seed germination | life history | GERMINATION | QUESTION | PLANT SCIENCES | EVOLUTION | INBREEDING DEPRESSION | PLANTS | ECOLOGY | TRAITS | SELF-FERTILIZATION
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14. Full Text Highly selective cyclooxygenase-1 inhibitors P6 and mofezolac counteract inflammatory state both in vitro and in vivo models of neuroinflammation
by Calvello, Rosa and Lofrumento, Dario Domenico and Perrone, Maria Grazia and Cianciulli, Antonia and Salvatore, Rosaria and Vitale, Paola and De Nuccio, Francesco and Giannotti, Laura and Nicolardi, Giuseppe and Panaro, Maria Antonietta and Scilimati, Antonio
Frontiers in Neurology, ISSN 1664-2295, 06/2017, Volume 8, p. 251
Activated microglia secrete an array of pro-inflammatory factors, such as prostaglandins, whose accumulation contributes to neuronal damages. Prostaglandin... 
In vitro and in vivo experiments | Cyclooxygenase-1 inhibitors | Neuroinflammation | Cyclooxygenase-1 | Lipopolysaccharide-treated BV2 microglial cells | P6 and mofezolac | ACTIVATION | ALZHEIMERS-DISEASE | cyclooxygenase-1 | COX-1 INHIBITORS | INJURY | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | cyclooxygenase-1 inhibitors | RESPONSES | neuroinflammation | MICROGLIA | in vitro and in vivo experiments | lipopolysaccharide-treated BV2 microglial cells | MICE | EXPRESSION | BRAIN
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15. Full Text The italian music superdiversity: Geography, emotion and language: one resource to find them, one resource to rule them all
by Pollacci, Laura and Guidotti, Riccardo and Rossetti, Giulio and Giannotti, Fosca and Pedreschi, Dino
Multimedia Tools and Applications, ISSN 1380-7501, 02/2019, Volume 78, Issue 3, pp. 3297 - 3319
Globalization can lead to a growing standardization of musical contents. Using a cross-service multi-level dataset we investigate the actual Italian music... 
Music data analytics | Music sentiment analytics | Multi-source analytics | Superdiversity | Music sentiment analysis | Sentiment pattern discovery | COMPUTER SCIENCE, SOFTWARE ENGINEERING | COMPUTER SCIENCE, INFORMATION SYSTEMS | COMPUTER SCIENCE, THEORY & METHODS | ENGINEERING, ELECTRICAL & ELECTRONIC | Computer science | Analysis | Algorithms
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16. Full Text Solid State Investigation and Characterization of a Nepadutant Precursor: Polymorphic and Pseudopolymorphic Forms of MEN11282
by Paoli, Paola and Rossi, Patrizia and Chelazzi, Laura and Altamura, Maria and Fedi, Valentina and Giannotti, Danilo
Crystal Growth & Design, ISSN 1528-7483, 09/2016, Volume 16, Issue 9, pp. 5294 - 5304
MEN11282 (1) is a precursor of nepadutant (MEN11420), a potent and selective antagonist at the human tachykinin NK-2 receptor (hNK-2), that has been evaluated... 
TRANSITION | X-RAY-DIFFRACTION | RECEPTOR | CRYSTALLOGRAPHY | CHEMISTRY, MULTIDISCIPLINARY | MATERIALS SCIENCE, MULTIDISCIPLINARY
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17. Full Text Declarative interference affects off-line processing of motor imagery learning during both sleep and wakefulness
by Debarnot, Ursula and Castellani, Eleonora and Guillot, Aymeric and Giannotti, Veronica and Dimarco, Mattia and Sebastiani, Laura
Neurobiology of Learning and Memory, ISSN 1074-7427, 11/2012, Volume 98, Issue 4, pp. 361 - 367
► We examine the effects of declarative interference in MI learning and consolidation. ► Declarative interference affects overnight- and day MI consolidation.... 
Movement imagery | Sequential motor learning | Sleep | Declarative interference | Motor consolidation | SYSTEM | SKILL | TIME-COURSE | NEUROSCIENCES | PSYCHOLOGY | IMPLICIT | PSYCHOLOGY, MULTIDISCIPLINARY | MEMORY CONSOLIDATION | SEQUENCE | BEHAVIORAL SCIENCES | MENTAL PRACTICE | IMPROVEMENTS | Humans | Male | Verbal Learning - physiology | Imagination - physiology | Retention (Psychology) - physiology | Psychomotor Performance - physiology | Young Adult | Movement - physiology | Analysis of Variance | Perceptual Masking | Time Factors | Mental Recall - physiology | Wakefulness - physiology | Adult | Female | Sleep - physiology | Memory - physiology | Learning | Memory | Motor ability | Neurobiology | mental task performance | Physical training | Daytime | Motor skill learning | Finger | Nervous system | Motor task performance | Sleep and wakefulness
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18. Full Text Vitamin D Treatment Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in an Animal Model of Parkinson's Disease, Shifting M1 to M2 Microglia Responses
by Calvello, R and Cianciulli, A and Nicolardi, G and De Nuccio, F and