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by Mullen, Michael and Jin, Xu Yu and Child, Anne and Stuart, A Graham and Dodd, Matthew and Aragon-Martin, José Antonio and Gaze, David and Kiotsekoglou, Anatoli and Yuan, Li and Hu, Jiangting and Foley, Claire and Van Dyck, Laura and Knight, Rosemary and Clayton, Tim and Swan, Lorna and Thomson, John D R and Erdem, Guliz and Crossman, David and Flather, Marcus and Dean, John and Was, Bartosz and Gow, Heather and Murray, Jane and D'Allessandro, Mariella and Christie, Michael and Cooper, Patricia and Booth, Philip and Burns, Sharon and Paterson, Yvonne and Chikermane, Ashish and Assing, Anthony and Cotter, Catherine and Atkins, Gillian and Williamson, Helen and Barclay, Justin and Jennison, Alan and Henderson, Alex and McSkeane, Anna and Fairlamb, Helen and Kelly, Julie and Kelsall, Nicola and Prentice, Scott and O'Sullivan, John and Head-Baister, Alison and Phillipson, Angela and Johnson, Anna and Crossland, D and Oliver, Jack and Davison, Jade and Wake, Jill and Quinn, Louise and Foreman, Maureen and Wealleans, Vera and Walker, Niki and Duncan, Alexis and Tibbs, Evelyn and Kelly, Ruth and Khambadkone, Sachin and Zotti, Bridget and Brady, Cassie and Cervi, Elena and Field, Ella and Szepezvary, Eszter and Mantey, Florence and Riley, Gillian and Titmus, Heather and Bo, Ilaria and Kaski, Juan Pablo and Green, Loren and Jones, Nigel and Banks, Rebecca and Kiesewetter, Christopher and Mathur, Sujeev and Frigiola, Alessandra and Savis, Alex and Belfield, Holly and Guzman, Josephine and Harris, Julia and Wilson, Karen and Peacock, Kelly and Gibson, Kirsty and Wellman, Paul and Simpson, John and Kabir, Saleha and Mushemi, Sitali and Stewart, Michael and Atkinson, Bev and Richardson, Cath and Leng, Elaine and Brennan, Paul and Nixon, Annabel and Spencer, Collette and Oliver, James and Forster, Jan and Turner, Louise and Bainbridge, Samantha and Choy, Anna Maria and Dawson, Adelle and Kiddie, Gwen and Kerr, Heather and ... and AIMS Investigators
The Lancet, ISSN 0140-6736, 12/2019, Volume 394, Issue 10216, pp. 2263 - 2270
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e55468
... of Biology, University of British Columbia Okanagan, Kelowna, British Columbia, Canada Kirsty Brown Affiliation: Department of Biology, University of British Columbia... 
DEFENSE | INTESTINAL ALKALINE-PHOSPHATASE | CROHNS-DISEASE | LINOLEIC-ACID | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | ESCHERICHIA-COLI | SUSCEPTIBILITY | LIPOPOLYSACCHARIDE | MICROBIOTA | Tumor Necrosis Factor-alpha - metabolism | Intestinal Mucosa - metabolism | Alkaline Phosphatase - metabolism | Fatty Acids, Omega-3 - toxicity | Intestinal Mucosa - drug effects | Citrobacter rodentium - metabolism | Fatty Acids, Omega-6 - pharmacology | Fatty Acids, Omega-3 - pharmacology | Sepsis - metabolism | Colitis - chemically induced | Female | Enterobacteriaceae Infections - metabolism | Enterobacteriaceae Infections - microbiology | Mice, Inbred C57BL | Intestinal Mucosa - microbiology | Fish Oils - pharmacology | Dinoprostone - metabolism | Animals | Colitis - microbiology | Fatty Acids, Omega-6 - toxicity | Sepsis - chemically induced | Diet | Interleukin-15 - metabolism | Colitis - metabolism | Lipopolysaccharides - pharmacology | Mice | Dietary Supplements | Sepsis - microbiology | Microbiota (Symbiotic organisms) | Analysis | Prostaglandins E | Development and progression | Disease susceptibility | Inflammation | Ulcerative colitis | Protein binding | Enrichment | Alkaline phosphatase | Animal models | Dysbacteriosis | Inflammatory bowel diseases | Disease | Polyunsaturated fatty acids | Weaning | Prostaglandin E2 | Biology | Infections | Dephosphorylation | Phosphatase | Immunity | Lipopolysaccharides | Proteins | Microorganisms | Microbiota | Corn oil | Intestine | Rodents | Bacteria | Supplementation | Intestinal microflora | Citrobacter | Translocation | Cytokines | Nutrition | Fish oils | Mortality | Dietary supplements | Corn | Tumor necrosis factor-α | Metabolism | Interleukin 15 | Fatty acids | Inflammatory bowel disease | Probiotics | Filamentous bacteria | Sepsis | Oils & fats | Infiltration
Journal Article
eLife, ISSN 2050-084X, 08/2014, Volume 3, Issue 2014, pp. 1 - 17
The Cdc45/Mcm2-7/GINS ( CMG) helicase separates DNA strands during replication in eukaryotes. How the CMG is assembled and engages DNA substrates remains... 
replication fork | DNA replication | helicase | motor proteins | AAA+ ATPase | Mcm2-7 | MCM2-7 HELICASE | HEXAMERIC HELICASE | MINICHROMOSOME MAINTENANCE PROTEIN | ARCHAEAL MCM | BUDDING YEAST | STRUCTURAL BASIS | BIOLOGY | REPLICATIVE HELICASE | ELECTRON-MICROSCOPY | 26S PROTEASOME | CRYO-EM STRUCTURE | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Eukaryotic Cells - metabolism | Drosophila Proteins - metabolism | Minichromosome Maintenance Proteins - chemistry | Protein Subunits - metabolism | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Drosophila melanogaster - metabolism | Multiprotein Complexes - metabolism | Adenosine Triphosphate - metabolism | Protein Structure, Quaternary | Repressor Proteins - metabolism | Protein Structure, Tertiary | Repressor Proteins - chemistry | Chromosomal Proteins, Non-Histone - metabolism | DNA, Single-Stranded - metabolism | RNA-Binding Proteins - chemistry | Cell Cycle Proteins - metabolism | RNA Splicing Factors | Adenosine Triphosphatases - metabolism | Models, Molecular | DNA Replication | DNA - metabolism | Drosophila Proteins - chemistry | Microscopy, Electron | DNA-Binding Proteins - chemistry | Adenosine Triphosphate - analogs & derivatives | DNA, Single-Stranded - chemistry | Multiprotein Complexes - ultrastructure | DNA - chemistry | Multiprotein Complexes - chemistry | Animals | Protein Binding | Adenosine Triphosphatases - chemistry | Protein Subunits - chemistry | Adenosine Triphosphate - chemistry | Chromosomal Proteins, Non-Histone - chemistry | RNA-Binding Proteins - metabolism | Medical research | Single-stranded DNA | Hexamers | Electron microscopy | DNA biosynthesis | DNA helicase | Handedness | Microscopy | Insects | Cdc45 protein | Cell cycle | Polarity | Dimerization | Deoxyribonucleic acid--DNA | Adenosine triphosphatase
Journal Article
Vaccine, ISSN 0264-410X, 2017, Volume 35, Issue 18, pp. 2489 - 2495
Highlights • Tetanus toxoid (TTxd) is poorly immunogenic in transcutaneous immunisation (TCI). • TCI with TTxd-Soluplus® increased the tetanus toxin... 
Allergy and Immunology | Neutralising antibodies | Transcutaneous delivery | Polymeric micelles | Nanotechnology | Tetanus toxoid | MEDICINE, RESEARCH & EXPERIMENTAL | HEAT-LABILE ENTEROTOXIN | ESCHERICHIA-COLI | VACCINE DELIVERY | HYDROGEL PATCH | IMMUNOLOGY | ADP-RIBOSYLATING EXOTOXINS | IN-VITRO | T-CELL RESPONSES | IMMUNE-RESPONSES | SKIN PENETRATION | LOW-FREQUENCY ULTRASOUND | Adjuvants, Immunologic - administration & dosage | Antitoxins - blood | Tetanus - prevention & control | Administration, Cutaneous | Rats, Sprague-Dawley | Polyethylene Glycols - administration & dosage | Tetanus Toxoid - administration & dosage | Animals | Polyvinyls - administration & dosage | Antibody Formation | Immunization, Passive | Female | Mice | Nanoparticles - administration & dosage | Tetanus Toxoid - immunology | Antibodies, Neutralizing - blood | Disease Models, Animal | Viral antibodies | Antibodies | Immunization | Biological products | Tetanus | Animal experimentation | Skin | Abrasion | Drinking water | Peptides | Mucosa | Hyperplasia | Caprolactam | Vaccines | Antibody response | Proteins | Fabrication | Ultrasonic imaging | Anesthesia | Polymers | Deoxyribonucleic acid--DNA | Antigens | Spectroscopy | Solvents | Evaluation | Gels | Organic solvents | Macromolecules | Distilled water | Adjuvants | Bioavailability | Abdomen | Carriers | Abrasion resistance | Protective equipment | Antigen-presenting cells | Chitosan | Environmental monitoring | Drugs | Polyethylenes | Particle size | Animal models | Attitude control | Colloids | Clinical trials | Lipids | Infections | Alcohols | Pain | Immunology | Aqueous solutions | Bioactive compounds | Calcitonin | Ultrasound | Technology utilization | Immune system | Formulations | Statistical analysis | Health risks | Pharmacology | Inflammation | Biological activity | Homogeneity | Cholera | Reproductive system
Journal Article
Nutrients, ISSN 2072-6643, 02/2019, Volume 11, Issue 2, p. 418
The dynamics of the tripartite relationship between the host, gut bacteria and diet in the gut is relatively unknown. An imbalance between harmful and... 
16S rRNA gene amplicon sequencing | Host-microbe interactions | Monounsaturated fatty acids | Short-chain fatty acid metabolism | Polyunsaturated fatty acids | Dietary lipids | Proteome | Gut microbiome | Saturated fatty acids | ETIOLOGY | SEARCH | polyunsaturated fatty acids | ULCERATIVE-COLITIS | RATS | RISK | short-chain fatty acid metabolism | FATTY-ACIDS | MICROBIOTA | monounsaturated fatty acids | proteome | NUTRITION & DIETETICS | gut microbiome | dietary lipids | INFLAMMATORY-BOWEL-DISEASE | DYSBIOSIS | saturated fatty acids | RICH | Milk - chemistry | Fatty Acids - chemistry | Mice, Inbred C57BL | RNA, Ribosomal, 16S - analysis | Male | Olive Oil - administration & dosage | Intestinal Mucosa - microbiology | Gastrointestinal Microbiome - genetics | Corn Oil - administration & dosage | Fats - chemistry | Animals | Dietary Fats - administration & dosage | Female | Colon - microbiology | Mice | Diet, High-Fat - methods | Sirtuins | Keystone species | Mucosa | Microbiomes | Homeostasis | Lipids | Inflammatory diseases | Butyric acid | Cell adhesion & migration | Proteins | Signal transduction | Microorganisms | Corn oil | Stress response | Deoxyribonucleic acid--DNA | Milk | Nutrient deficiency | Cytokines | Cecum | Abundance | Inflammation | Olive oil | Bioavailability | Mammals | Metabolism | Fatty acids | Inflammatory bowel disease | Nutrition research | Biofilms | Diet | Saturation index | Low fat diet | Oils & fats | Sepsis | Metabolic pathways | Diabetes
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e70248
... Kirsty Brown Affiliation: Department of Biology, IK Barber School of Arts and Sciences, University of British Columbia-Okanagan, Kelowna, British Columbia, Canada... 
PATHWAYS | OXIDATIVE STRESS | ACTIVATION | HOMEOSTASIS | BIOGENESIS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL CONTROL | WEIGHT-LOSS | MODERATE-INTENSITY EXERCISE | HYPERGLYCEMIC STATUS | DIET-INDUCED OBESITY | Inflammation - pathology | Up-Regulation | Oxidative Stress | Transcriptional Activation | Male | Diabetes Mellitus, Type 2 - metabolism | RNA, Messenger - metabolism | Inflammation - metabolism | DNA, Mitochondrial - genetics | Cell Respiration | Myocardium - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Membrane Proteins - metabolism | Physical Conditioning, Animal | RNA, Messenger - genetics | Diabetes Mellitus, Type 2 - enzymology | Oxidative Phosphorylation | Myocardium - pathology | Transcription Factors - genetics | Aging - pathology | Mitochondrial Membranes - metabolism | Transcription Factors - metabolism | Myocytes, Cardiac - pathology | Myocardium - enzymology | Animals | Inflammation - genetics | Myocytes, Cardiac - metabolism | Mice | Diabetes Mellitus, Type 2 - pathology | Aging - metabolism | Heart | Oxidative stress | Transcription factors | Phosphorylation | Hydrogen peroxide | Respiratory enzymes | Downstream effects | Body weight | Genes | Biosynthesis | Biology | Glucose | Macrophages | Proteins | Mitochondria | Exercise | Rodents | Animal tissues | Aging | Fitness training programs | Heart diseases | Age | Obesity | Enzymes | Cytokines | Diabetes mellitus | Cardiomyocytes | Inflammation | Tumor necrosis factor-α | Metabolism | Gene expression | Insulin | Nitric-oxide synthase | Membrane proteins | Musculoskeletal system | Physical fitness | Weight control | Oxidative phosphorylation | Infiltration | Diabetes | Chemokines
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0142751
Journal Article