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Human Molecular Genetics, ISSN 0964-6906, 07/2018, Volume 27, Issue 14, pp. 2443 - 2453
Abstract The signaling lipid phosphatidylinositol 3,5-bisphosphate, PI(3,5)P2, functions in vesicular trafficking through the endo-lysosomal compartment.... 
YUNIS-VARON SYNDROME | MYELIN | PHOSPHOINOSITIDE PHOSPHATASE | NULL MOUSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | NEURONAL EXPRESSION | NEURODEGENERATION | REMYELINATION | PHOSPHATIDYLINOSITOL 3,5-BISPHOSPHATE | MUTATIONS | REMAK SCHWANN-CELLS | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2016, Volume 113, Issue 12, pp. 3130 - 3132
Journal Article
Journal of Cell Science, ISSN 0021-9533, 05/2016, Volume 129, Issue 10, pp. e1.2 - e1.2
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2011, Volume 31, Issue 48, pp. 17736 - 17751
The plt (pale tremor) mouse carries a null mutation in the Fig4(Sac3) gene that results in tremor, hypopigmentation, spongiform degeneration of the brain, and... 
PROMOTE MYELINATION | MUTATION | NOGO-66 RECEPTOR | NEURODEGENERATION | CENTRAL-NERVOUS-SYSTEM | HOMOLOG NGR2 | DEATH | ASTROCYTES | NEUROSCIENCES | MYELIN-ASSOCIATED GLYCOPROTEIN | PHOSPHOINOSITIDES
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 02/2015, Volume 112, Issue 8, p. 2581
Innate immunity can facilitate nervous system regeneration, yet the underlying cellular and molecular mechanisms are not well understood. Here we show that... 
Physiological aspects | Axons | Inflammation | Cellular signal transduction | Observations | Health aspects | Molecules | Signal transduction | Rodents | Pattern recognition | Kinases | Neurological disorders | Inflammatory diseases
Journal Article
Neuron, ISSN 0896-6273, 06/2011, Volume 70, Issue 5, pp. 808 - 812
Vascular endothelial growth factor (VEGF) family members are best known for their powerful mitotic and angiogenic activities toward endothelial cells. Two... 
GANGLION-CELL AXONS | SONIC HEDGEHOG | SEMAPHORIN | GROWTH | BOC | RECEPTOR | GUIDANCE | NEUROSCIENCES | Zebrafish | Nervous system | Spinal cord | Neural networks | Vascular endothelial growth factor | commissural axons | VEGF-A | Flk1 | neuropilin-1 | chemoattraction
Journal Article
Science Signaling, ISSN 1945-0877, 02/2010, Volume 3, Issue 110, p. pe6
Journal Article
Neuron, ISSN 0896-6273, 03/2016, Volume 89, Issue 5, pp. 881 - 884
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2012, Volume 15, Issue 5, pp. 703 - 712
In the adult mammalian CNS, chondroitin sulfate proteoglycans (CSPGs) and myelin-associated inhibitors (MAIs) stabilize neuronal structure and restrict... 
RETINAL GANGLION-CELLS | NEURITE GROWTH | AXON REGENERATION | OPTIC-NERVE REGENERATION | SPINAL-CORD-INJURY | TYROSINE-PHOSPHATASE-SIGMA | CORTICOSPINAL TRACT REGENERATION | NOGO RECEPTOR | OLIGODENDROCYTE-MYELIN GLYCOPROTEIN | FUNCTIONAL RECEPTOR | NEUROSCIENCES | Protein Binding - genetics | Embryo, Mammalian | Humans | Myelin Proteins - deficiency | Nerve Regeneration - physiology | Myelin-Associated Glycoprotein - genetics | Myelin-Associated Glycoprotein - metabolism | Ganglia, Spinal - cytology | Dose-Response Relationship, Drug | Tubulin - metabolism | Transfection | GPI-Linked Proteins - deficiency | Receptor-Like Protein Tyrosine Phosphatases, Class 4 - pharmacology | Protein Binding - drug effects | Optic Nerve Injuries - metabolism | Neurons - metabolism | Nogo Receptor 1 | Neurons - drug effects | Receptors, Tumor Necrosis Factor - genetics | Animals, Newborn | Receptors, Tumor Necrosis Factor - metabolism | Gene Expression Regulation - genetics | Cells, Cultured | Chondroitin Sulfate Proteoglycans - metabolism | Gene Expression Regulation - physiology | Rats | Receptors, Cell Surface - metabolism | Mutation - genetics | Myelin Proteins - genetics | GPI-Linked Proteins - metabolism | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Analysis of Variance | Central Nervous System - cytology | Receptors, Cell Surface - deficiency | Mice | Myelin Proteins - metabolism | GPI-Linked Proteins - genetics | Receptors, Cell Surface - genetics | Neuroplasticity | Physiological aspects | Proteoglycans | Research | Chondroitin | Index Medicus
Journal Article
eLife, ISSN 2050-084X, 03/2016, Volume 5
Proper development of the CNS axon-glia unit requires bi-directional communication between axons and oligodendrocytes (OLs). We show that the signaling lipid... 
Dendritic cells | Physiological aspects | Biosynthesis | Observations | Cell differentiation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 8, pp. 2581 - 2586
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 12, pp. 3130 - 3132
Journal Article
Neuron, ISSN 0896-6273, 02/2012, Volume 73, Issue 3, pp. 466 - 481
Neuronal development is characterized by a period of exuberant synaptic growth that is well studied. However, the mechanisms that restrict this process are... 
NMDA RECEPTOR | MYELIN | INHIBITION | REGENERATION | TRANSCRIPTION | DENDRITIC SPINE | RHO | GLYCOPROTEIN | NEUROSCIENCES | PLASTICITY | Disks Large Homolog 4 Protein | RNA, Small Interfering - genetics | Age Factors | Myelin Proteins - deficiency | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | rhoA GTP-Binding Protein - metabolism | Dendrites - ultrastructure | Green Fluorescent Proteins - genetics | Transfection - methods | GPI-Linked Proteins - deficiency | Neurons - physiology | Membrane Proteins - metabolism | Nogo Receptor 1 | Hippocampus - growth & development | Organ Culture Techniques | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Receptors, Tumor Necrosis Factor - metabolism | Microscopy, Electron, Transmission | Synapses - physiology | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, Transgenic | Synapses - ultrastructure | Signal Transduction - genetics | Hippocampus - cytology | GPI-Linked Proteins - metabolism | Microscopy, Confocal | Animals | Receptors, Cell Surface - deficiency | Glutamate Decarboxylase - metabolism | Guanylate Kinases - metabolism | Mice | Myelin Proteins - metabolism | Dendrites - genetics | RNA, Small Interfering - metabolism | Brain | Developmental biology | Neurons | Proteins | Ligands | Kinases | Experiments | Index Medicus | Axonogenesis
Journal Article
Neuron, ISSN 0896-6273, 2011, Volume 71, Issue 3, pp. 460 - 473
Journal Article