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Journal Article
Diabetes, ISSN 0012-1797, 03/2013, Volume 62, Issue 3, pp. 732 - 742
Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders... 
COMPLEX | EPIGENETICS | MECHANISM | PHOSPHORYLATION | BROWN ADIPOCYTES | ENDOCRINOLOGY & METABOLISM | BUTYRATE | DIFFERENTIATION | PPAR-GAMMA ACTIVATION | INSULIN SENSITIVITY | EXPRESSION | Obesity - drug therapy | Mitochondria, Muscle - metabolism | Adipose Tissue - cytology | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Molecular Targeted Therapy | Anti-Obesity Agents - therapeutic use | Adipose Tissue - metabolism | Mice, Mutant Strains | Muscle, Skeletal - drug effects | Histone Deacetylase 1 - antagonists & inhibitors | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cell Line | Histone Deacetylase 2 - antagonists & inhibitors | Obesity - complications | Cells, Cultured | Muscle, Skeletal - ultrastructure | Random Allocation | Hypoglycemic Agents - pharmacology | Obesity - metabolism | Obesity - pathology | Gene Expression Regulation - drug effects | Animals | Adipose Tissue - ultrastructure | Histone Deacetylase Inhibitors - pharmacology | Mitochondria, Muscle - ultrastructure | Histone Deacetylase Inhibitors - therapeutic use | Mice | Mitochondria, Muscle - drug effects | Diabetes Mellitus, Type 2 - pathology | Histone Deacetylase 2 - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue - drug effects | Anti-Obesity Agents - pharmacology | Energy Metabolism - drug effects | Histone Deacetylase 1 - metabolism | Type 2 diabetes | Care and treatment | Enzyme inhibitors | Histones | Cell metabolism | Muscles | Physiological aspects | Research | Acetylation | Index Medicus | Abridged Index Medicus | Metabolism
Journal Article
Journal of Inflammation (United Kingdom), ISSN 1476-9255, 02/2015, Volume 12, Issue 1, pp. 14 - 14
Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an imbalance in cell fate decision. IR is able to regulate several... 
Ionizing radiation | Inflammation | Invasiveness | Cytokine | Fibrosis | TGF-BETA | GENE-EXPRESSION PROFILES | IMMUNOLOGY | MESSENGER-RNA LEVELS | FACTOR-ALPHA | EPITHELIAL-MESENCHYMAL TRANSITION | GROWTH-FACTOR-BETA | IN-VITRO | SIGNALING PATHWAY | BREAST-CANCER PATIENTS | NF-KAPPA-B | Immune response | Research | Cell death | Oncology, Experimental | Genes | Cancer
Journal Article
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2019, Volume 25, Issue 1, pp. 7 - 12
Introduction: Biosimilars present a considerable potential to reduce costs related to clinical management allowing health-care providers to reinvest this... 
MODERATE | DIAGNOSIS | MANAGEMENT | SAFETY | Crohn's disease | CLINICAL SIMILARITY | inflammatory bowel disease | ABP 501 | IMMUNOGENICITY | EVIDENCE-BASED CONSENSUS | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ulcerative colitis | Adalimumab | INFLIXIMAB | biosimilar | monoclonal antibodies
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, pp. e0171474 - e0171474
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a ligand-dependent transcription factor involved in many aspects of metabolism, immune... 
DIABETIC COMPLICATIONS | ANTIBODIES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | DISEASE | ACTIVATED-RECEPTOR-GAMMA | LIPODYSTROPHY | LUPUS-ERYTHEMATOSUS | MECHANISMS | ANTIPHOSPHOLIPID SYNDROME | Diabetic Nephropathies - pathology | Kidney - pathology | Signal Transduction | Diabetic Nephropathies - metabolism | Kidney - immunology | Homeostasis | Diabetic Nephropathies - genetics | PPAR gamma - metabolism | Complement C3 - immunology | Antiphospholipid Syndrome - immunology | Immunoglobulin M - metabolism | Kidney - metabolism | Animals | Antiphospholipid Syndrome - pathology | Antibodies - immunology | Antiphospholipid Syndrome - genetics | Mice | beta 2-Glycoprotein I - immunology | Immunoglobulin G - metabolism | PPAR gamma - genetics | Immunoglobulin M | Syngeneic grafts | Pathogenesis | Genomics | Immunoglobulin G | Immune clearance | Antibodies | Cardiovascular disease | Biology | Metabolic syndrome | Renal insufficiency | Alterations | Immunology | Clonal deletion | Rodents | Deletion | Thromboembolism | Diabetes mellitus (non-insulin dependent) | Immune system | Lupus | Creatinine | Immunoglobulins | Immune response | Kidneys | Diabetes mellitus | Metabolism | Embryos | Thrombosis | Immune systems | Medicine | Signaling | Hospitals | Nephropathy | Lipoatrophy | Fibrosis | Alleles | Stem cells | Ligands | Kidney diseases | Peroxisome proliferator-activated receptors | Diabetes | Gene therapy | Hypertrophy | Antiphospholipid syndrome | Structure-function relationships | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-391 - S-392
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 40, pp. 39124 - 39132
Journal Article
PLoS Biology, ISSN 1544-9173, 04/2017, Volume 15, Issue 4, pp. e2001069 - e2001069
Many organisms exhibit temporal rhythms in gene expression that propel diurnal cycles in physiology. In the liver of mammals, these rhythms are controlled by... 
HEPATIC GLUCONEOGENESIS | HUMAN GENOME | CHROMATIN LANDSCAPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COORDINATE DESCENT | IN-VIVO | BIOLOGY | DNA-BINDING PROTEINS | REV-ERB-ALPHA | HISTONE MODIFICATIONS | CIRCADIAN GENE-EXPRESSION | STRUCTURE PREDICTION | Promoter Regions, Genetic | ARNTL Transcription Factors - genetics | Fasting | Deoxyribonuclease I - genetics | Mice, Inbred C57BL | Circadian Rhythm - genetics | Gene Expression Regulation | ARNTL Transcription Factors - metabolism | Male | CLOCK Proteins - genetics | Circadian Clocks - genetics | Transcription Factors - genetics | Mice, Knockout | CLOCK Proteins - metabolism | Deoxyribonuclease I - metabolism | Multiprotein Complexes - metabolism | Animals | Chromatin Immunoprecipitation | Liver - physiology | RNA Polymerase II - genetics | Transcription, Genetic | Bioengineering | High resolution | Transcription factors | Genomics | Liver | Modules | Biochemistry | Assaying | Loads (forces) | Proteins | Eukaryotes | Life sciences | Bioinformatics | Deoxyribonucleic acid--DNA | Circadian rhythms | Nucleic acids | Gene expression | Mammals | Metabolism | Diurnal | Generalized linear models | Computer applications | Mice | Protein structure | Binding sites | DNA sequencing | Health sciences | Visualization | Chromatin | Animal models | Gene regulation | Genomes | Biology | DNA-directed RNA polymerase | Nanoparticles | Rodents | Dimensional analysis | Hepatocyte nuclear factor 4 | Mathematical models | Adrenal gland | Hepatocyte nuclear factor 1 | Deoxyribonuclease | Data analysis | Hypersensitivity | Diabetes mellitus | Data processing | Circadian rhythm | Ribonucleic acid--RNA | Computer programs | Feeding | Medicine | BMAL1 protein | Diabetes | Control theory | Molecular biology | Index Medicus | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article