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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1661-6596, 08/2019, Volume 20, Issue 15, p. 3612
The Rho GTPase family can be classified into classic and atypical members. Classic members cycle between an inactive Guanosine DiPhosphate -bound state and an... 
CA2+ SENSITIZATION | response to anticancer agents | ACTIVATING PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR GENES | RND | CANCER | CHEMISTRY, MULTIDISCIPLINARY | FAMILY | R-RAS | PATTERN | prognosis factor | oncogenesis | GROWTH | migration | RHO-GTPASES | Rho GTPase | EXPRESSION
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 910 - 14
Journal Article
Computers in Biology and Medicine, ISSN 0010-4825, 12/2017, Volume 91, pp. 159 - 167
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 2041 - 2041
Journal Article
Acta Dermato-Venereologica, ISSN 0001-5555, 02/2019, Volume 99, Issue 2, pp. 206 - 210
Antibodies targeting immune checkpoints were recently approved for metastatic melanoma. However, not all patients will respond to the treatment and some will... 
Therapeutic response | Biomarker | CtDNA | Immunotherapy | Melanoma | ANTIBODIES | DIGITAL PCR | CELLS | COMBINED NIVOLUMAB | ACQUIRED-RESISTANCE | melanoma | biomarker | ctDNA | therapeutic response | DERMATOLOGY | immunotherapy | LIQUID BIOPSIES | MUTATIONS | IPILIMUMAB
Journal Article
Cell Death and Disease, ISSN 2041-4889, 09/2018, Volume 9, Issue 9, pp. 872 - 12
Radiotherapy is the cornerstone of glioblastoma (GBM) standard treatment. However, radioresistance of cancer cells leads to an inevitable recurrence. In the... 
GLIOMAS | ADHESION | STEM-CELLS | INVASION | METASTASIS | PATHWAY | THERAPY RESISTANCE | MESENCHYMAL TRANSITION | CANCER | EXPRESSION | CELL BIOLOGY | Cell survival | Therapeutic applications | CHK1 protein | DNA damage | Glioblastoma | Olig2 protein | Radioresistance | Radiation therapy | DNA repair | Cell death | Biopsy | Neurospheres | Deoxyribonucleic acid--DNA | Cancer
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 04/2019, Volume 10, p. 443
Sphingolipid (SL) metabolism alterations have been frequently reported in cancer including in melanoma, a bad-prognosis skin cancer. In normal cells, de novo... 
sphingolipids | GLUCOSYLCERAMIDE SYNTHASE | glucosylceramide | DRUG-RESISTANCE | ceramide | INHIBITION | METABOLISM | prognosis biomarker | PHARMACOLOGY & PHARMACY | cancer | MULTIDRUG-RESISTANCE | STRESS | EXPRESSION | Physiological aspects | Phospholipids | Prognosis | Melanoma | Skin cancer | Life Sciences
Journal Article
Bulletin du Cancer, ISSN 0007-4551, 01/2017, Volume 104, Issue 1, pp. 92 - 100
In the era of personalized medicine, treatment effect can no longer be considered homogeneous for all patients. Subgroups analyses are generally performed in... 
Subgroup analysis | Heterogeneity | Clinical trials | Multiplicity of test
Journal Article
BLOOD, ISSN 0006-4971, 06/2019, Volume 133, Issue 26, pp. 2741 - 2744
We previously reported a new form of light chain deposition disease (LCDD) presenting as diffuse cystic lung disorder that differs from the usual systemic form... 
GERMLINE GENE | CELLS | VARIABLE REGION | SYSTEMIC AMYLOIDOSIS | HEMATOLOGY | INVOLVEMENT | Life Sciences | Human health and pathology | Biochemistry, Molecular Biology | Genomics
Journal Article
Science Signaling, ISSN 1937-9145, 03/2017, Volume 10, Issue 472
Sphingosine kinase 1 (SphK1) promotes cell proliferation and survival, and its abundance is often increased in tumors. SphK1 produces the signaling lipid... 
Life Sciences | Microbiology and Parasitology | Immunology | Bacteriology | Virology
Journal Article
Science Signaling, ISSN 1945-0877, 03/2017, Volume 10, Issue 472, pp. eaah4007 - eaah4007
Sphingosine kinase 1 (SphK1) promotes cell proliferation and survival, and its abundance is often increased in tumors. SphK1 produces the signaling lipid... 
Journal Article
Oncotarget, ISSN 1949-2553, 08/2018, Volume 9, Issue 60, pp. 31637 - 31649
Glioblastoma are known to be aggressive and therapy-resistant tumors, due to the presence of glioblastoma stem cells inside this heterogeneous tumor. We... 
Radioresistance | Prognosis biomarker | FOX | Glioblastoma | FGFR1
Journal Article
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