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Cancer Gene Therapy, ISSN 0929-1903, 2019
Primary malignant central nervous system (CNS) tumors are the leading cause of childhood cancer-related death and morbidity. While advances in surgery,... 
Journal Article
Cells, ISSN 2073-4409, 07/2019, Volume 8, Issue 7, p. 702
Accurate patient-derived models of cancer are needed for profiling the disease and for testing therapeutics. These models must not only be accurate, but also... 
patient-derived xenografts (PDX) | Glioblastoma multiforme (GBM) | drug screening | NanoString | spheroids | INHIBITOR | CELL | SIGNATURE | microtumors | heterogeneity | CELL BIOLOGY
Journal Article
Translational oncology, ISSN 1936-5233, 02/2018, Volume 11, Issue 1, pp. 86 - 93
Malignant gliomas are the most common primary brain tumor and are characterized by rapid and highly invasive growth. Because of their poor prognosis, new... 
Journal Article
by Northcott, Paul A and Shih, David J. H and Peacock, John and Garzia, Livia and Sorana Morrissy, A and Zichner, Thomas and Stútz, Adrian M and Korshunov, Andrey and Reimand, Júri and Schumacher, Steven E and Beroukhim, Rameen and Ellison, David W and Marshall, Christian R and Lionel, Anath C and MacK, Stephen and Dubuc, Adrian and Yao, Yuan and Ramaswamy, Vijay and Luu, Betty and Rolider, Adi and Cavalli, Florence M. G and Wang, Xin and Remke, Marc and Wu, Xiaochong and Chiu, Readman Y. B and Chu, Andy and Chuah, Eric and Corbett, Richard D and Hoad, Gemma R and Jackman, Shaun D and Li, Yisu and Lo, Allan and Mungall, Karen L and Ming Nip, Ka and Qian, Jenny Q and Raymond, Anthony G. J and Thiessen, Nina and Varhol, Richard J and Birol, Inanc and Moore, Richard A and Mungall, Andrew J and Holt, Robert and Kawauchi, Daisuke and Roussel, Martine F and Kool, Marcel and Jones, David T. W and Witt, Hendrick and Fernandez-L, Africa and Kenney, Anna M and Wechsler-Reya, Robert J and Dirks, Peter and Aviv, Tzvi and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Haberler, Christine C and Delattre, Olivier and Reynaud, Stéphanie S and Doz, François F and Pernet-Fattet, Sarah S and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Scheurlen, Wolfram and Eberhart, Charles G and Fèvre-Montange, Michelle and Jouvet, Anne and Pollack, Ian F and Fan, Xing and Muraszko, Karin M and Yancey Gillespie, G and Di Rocco, Concezio and Massimi, Luca and Michiels, Erna M. C and Kloosterhof, Nanne K and French, Pim J and Kros, Johan M and Olson, James M and Ellenbogen, Richard G and Zitterbart, Karel and Kren, Leos and Thompson, Reid C and Cooper, Michael K and Lach, Boleslaw and McLendon, Roger E and Bigner, Darell D and Fontebasso, Adam and Albrecht, Steffen and Jabado, Nada and Lindsey, Janet C and Bailey, Simon and Gupta, Nalin and Weiss, William A and Bognár, László and Klekner, Almos and Van Meter, Timothy E and Kumabe, Toshihiro and Tominaga, Teiji and Elbabaa, Samer K and Leonard, Jeffrey R and Rubin, Joshua B and ...
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, pp. 49 - 56
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 312 - 312
Journal Article
Cancer Research, ISSN 0008-5472, 03/2001, Volume 61, Issue 5, pp. 2154 - 2161
Tumors of the central nervous system (CNS) often have sustained expression of labile genes, including angiogenic growth factors and immunosuppressive... 
POSTTRANSCRIPTIONAL REGULATION | NERVOUS-SYSTEM | DIFFERENTIAL EXPRESSION | ONCOLOGY | DROSOPHILA-MELANOGASTER | SENSORY NEURONOPATHY | IN-VIVO | FACTOR MESSENGER-RNA | DOWN-REGULATION | UP-REGULATION | GROWTH-FACTOR EXPRESSION | ELAV-Like Protein 1 | RNA-Binding Proteins - genetics | Humans | Brain Neoplasms - pathology | 3' Untranslated Regions - genetics | Molecular Sequence Data | 3' Untranslated Regions - metabolism | Meningioma - genetics | RNA, Messenger - metabolism | ELAV Proteins | Brain Neoplasms - metabolism | Uracil Nucleotides - metabolism | RNA-Binding Proteins - biosynthesis | Astrocytoma - pathology | Glioblastoma - genetics | Medulloblastoma - pathology | Glioblastoma - metabolism | Medulloblastoma - genetics | Cytokines - genetics | Gene Expression Regulation, Neoplastic - physiology | Astrocytoma - genetics | Astrocytoma - metabolism | Amino Acid Sequence | Angiogenesis Inducing Agents - biosynthesis | Meningioma - metabolism | RNA, Messenger - genetics | Brain Neoplasms - genetics | Medulloblastoma - metabolism | Disease Progression | Cell Division - physiology | Angiogenesis Inducing Agents - genetics | Meningioma - pathology | Adenine Nucleotides - metabolism | Glioblastoma - pathology | Neovascularization, Pathologic - genetics | Antigens, Surface | Neovascularization, Pathologic - metabolism | Cytokines - biosynthesis | RNA-Binding Proteins - metabolism
Journal Article
Journal Article
by Cavalli, Florence M.G and Remke, Marc and Rampasek, Ladislav and Peacock, John and Shih, David J.H and Luu, Betty and Garzia, Livia and Torchia, Jonathon and Nor, Carolina and Morrissy, A. Sorana and Agnihotri, Sameer and Thompson, Reid C and Thompson, Yuan Yao and Kuzan-Fischer, Claudia M and Farooq, Hamza and Isaev, Keren and Daniels, Craig and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Lee, Ji Yeoun and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Vasiljevic, Alexandre and Faure-Conter, Cecile and Jouvet, Anne and Giannini, Caterina and Nageswara Rao, Amulya A and Li, Kay Ka Wai and Ng, Ho-Keung and Eberhart, Charles G and Pollack, Ian F and Hamilton, Ronald L and Gillespie, G. Yancey and Olson, James M and Leary, Sarah and Weiss, William A and Lach, Boleslaw and Chambless, Lola B and Cooper, Michael K and Vibhakar, Rajeev and Hauser, Peter and van Veelen, Marie-Lise C and Kros, Johan M and French, Pim J and Ra, Young Shin and Kumabe, Toshihiro and López-Aguilar, Enrique and Zitterbart, Karel and Sterba, Jaroslav and Finocchiaro, Gaetano and Massimino, Maura and Van Meir, Erwin G and Osuka, Satoru and Shofuda, Tomoko and Klekner, Almos and Zollo, Massimo and Leonard, Jeffrey R and Rubin, Joshua B and Jabado, Nada and Albrecht, Steffen and Mora, Jaume and Van Meter, Timothy E and Jung, Shin and Moore, Andrew S and Hallahan, Andrew R and Chan, Jennifer A and Tirapelli, Daniela P.C and Carlotti, Carlos G and Fouladi, Maryam and Pimentel, José and Faria, Claudia C and Saad, Ali G and Massimi, Luca and Liau, Linda M and Wheeler, Helen and Nakamura, Hideo and Elbabaa, Samer K and Perezpeña-Diazconti, Mario and Chico Ponce de León, Fernando and Robinson, Shenandoah and Zapotocky, Michal and Lassaletta, Alvaro and Huang, Annie and Hawkins, Cynthia E and Tabori, Uri and Bouffet, Eric and Bartels, Ute and Dirks, Peter B and Rutka, James T and Bader, Gary D and Reimand, Jüri and Goldenberg, Anna and Ramaswamy, Vijay and Taylor, Michael D
Cancer Cell, ISSN 1535-6108, 06/2017, Volume 31, Issue 6, pp. 737 - 754.e6
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24665
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2008, Volume 3, Issue 11, p. e3655
Mitochondria dysfunction and hypoxic microenvironment are hallmarks of cancer cell biology. Recently, many studies have focused on isolation of brain cancer... 
BIOLOGY | Uncoupling Agents - pharmacology | Humans | Glycoproteins - metabolism | Peptides - genetics | DNA, Mitochondrial - physiology | Antigens, CD - genetics | Brain Neoplasms - metabolism | Antigens, CD - metabolism | Glioma - metabolism | Glioma - genetics | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Rotenone - pharmacology | Biomarkers, Tumor - metabolism | Stress, Physiological - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Energy Metabolism - genetics | Glycoproteins - genetics | Peptides - physiology | Stress, Physiological - genetics | Brain Neoplasms - genetics | Biomarkers, Tumor - physiology | AC133 Antigen | Glycoproteins - physiology | Models, Biological | Antigens, CD - physiology | Biomarkers, Tumor - genetics | Cell Hypoxia - genetics | Energy Metabolism - drug effects | Gliomas | Brain tumors | Stem cells | Mitochondrial DNA | Research | Electron transport | Intermediate filament proteins | Brain | Health sciences | Regulations | Nestin | Brain stem | Brain cancer | Genomes | Biology | Neurosurgery | Electron transport chain | Genotype & phenotype | Mitochondria | Bioenergetics | Glioma cells | Surgery | Physiology | Membrane potential | Deoxyribonucleic acid--DNA | Medical research | Free radicals | Environmental health | Pharmacology | Biophysics | Metabolism | Gene expression | Spheroids | Environmental conditions | Brain research | Glycolysis | Hypoxia | Mutation | Tumors | Cancer | Apoptosis | Deoxyribonucleic acid | DNA
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