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1. Full Text Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
by Totoki, Yasushi and Totoki, Yasushi and Tatsuno, Kenji and Covington, Kyle R and Ueda, Hiroki and Creighton, Chad J and Kato, Mamoru and Tsuji, Shingo and Donehower, Lawrence A and Slagle, Betty L and Nakamura, Hiromi and Yamamoto, Shogo and Shinbrot, Eve and Hama, Natsuko and Lehmkuhl, Megan and Hosoda, Fumie and Arai, Yasuhito and Walker, Kim and Dahdouli, Mahmoud and Gotoh, Kengo and Nagae, Genta and Gingras, Marie-Claude and Muzny, Donna M and Ojima, Hidenori and Shimada, Kazuaki and Midorikawa, Yutaka and Goss, John A and Cotton, Ronald and Hayashi, Akimasa and Shibahara, Junji and Ishikawa, Shumpei and Guiteau, Jacfranz and Tanaka, Mariko and Urushidate, Tomoko and Ohashi, Shoko and Okada, Naoko and Doddapaneni, Harsha and Wang, Min and Zhu, Yiming and Dinh, Huyen and Okusaka, Takuji and Kokudo, Norihiro and Kosuge, Tomoo and Takayama, Tadatoshi and Fukayama, Masashi and Gibbs, Richard A and Wheeler, David A and Aburatani, Hiroyuki and Shibata, Tatsuhiro
Nature genetics, ISSN 1061-4036, 12/2014, Volume 46, Issue 12, pp. 1267 - 1273
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Carcinoma, Hepatocellular - epidemiology | United States | Humans | Gene Expression Regulation, Neoplastic | Hepacivirus - genetics | Exome | Liver Neoplasms - epidemiology | TOR Serine-Threonine Kinases - genetics | Telomerase - genetics | DNA Mutational Analysis | Carcinoma, Hepatocellular - genetics | Principal Component Analysis | Carcinoma, Hepatocellular - ethnology | Genome, Viral | Liver Neoplasms - genetics | Japan | European Continental Ancestry Group | Models, Statistical | Liver Neoplasms - ethnology | Asian Continental Ancestry Group | Algorithms | Hepatitis B virus - genetics | CpG Islands | Mutation | Genome, Human | Medical research | Gene mutations | Medicine, Experimental | Development and progression | Genetic aspects | Hepatoma | Research | Medical statistics | Identification and classification | Liver cancer | Human papillomavirus | Data analysis | Genealogy | Research & development--R&D | Genomics | Software | Infections | Genomes | Chromosomes | Tumors | Index Medicus
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2. Full Text Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries
by Brisson, Marc and Kim, Jane J and Canfell, Karen and Drolet, Mélanie and Gingras, Guillaume and Burger, Emily A and Martin, Dave and Simms, Kate T and Bénard, Élodie and Boily, Marie-Claude and Sy, Stephen and Regan, Catherine and Keane, Adam and Caruana, Michael and Nguyen, Diep T N and Smith, Megan A and Laprise, Jean-François and Jit, Mark and Alary, Michel and Bray, Freddie and Fidarova, Elena and Elsheikh, Fayad and Bloem, Paul J N and Broutet, Nathalie and Hutubessy, Raymond
The Lancet (British edition), ISSN 0140-6736, 02/2020, Volume 395, Issue 10224, pp. 575 - 590
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Papillomavirus Infections - complications | Uterine Cervical Neoplasms - diagnosis | Early Detection of Cancer - methods | Humans | Uterine Cervical Neoplasms - epidemiology | Vaccination | Income | Uterine Cervical Neoplasms - prevention & control | Mass Screening - methods | Feasibility Studies | Incidence | Models, Biological | Papillomavirus Infections - prevention & control | Uterine Cervical Neoplasms - virology | Adult | Female | Developing Countries | Papillomavirus Vaccines | Women | Models | Diagnosis | Comparative analysis | Health aspects | Cervical cancer | Cancer | Low income groups | Vaccines | Consortia | Prevention | Reduction | Human papillomavirus | Human papilloma viruses | Dynamic models | Modelling | Public health | Age | Medical research | Immunization | High income | Sensitivity analysis | Thresholds | Cervix | Medical screening | Cellular biology | Womens health | Predictions | Index Medicus | Abridged Index Medicus
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3. Full Text The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation
by Yan, Ming and Gingras, Marie-Claude and Dunlop, Elaine A and Nouet, Yann and Dupuy, Fanny and Jalali, Zahra and Possik, Elite and Coull, Barry J and Kharitidi, Dmitri and Dydensborg, Anders Bondo and Faubert, Brandon and Kamps, Miriam and Sabourin, Sylvie and Preston, Rachael S and Davies, David Mark and Roughead, Taren and Chotard, Laetitia and van Steensel, Maurice A. M and Jones, Russell and Tee, Anew R and Pause, Arnim
The Journal of clinical investigation, ISSN 0021-9738, 06/2014, Volume 124, Issue 6, pp. 2640 - 2650
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Proto-Oncogene Proteins - metabolism | Cell Line | AMP-Activated Protein Kinases - metabolism | Tumor Suppressor Proteins - metabolism | Reactive Oxygen Species - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Proto-Oncogene Proteins - deficiency | Hypoxia-Inducible Factor 1 - metabolism | Birt-Hogg-Dube Syndrome - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | Energy Metabolism | Cell Transformation, Neoplastic | Tumor Suppressor Proteins - deficiency | Adenosine Triphosphate - metabolism | Birt-Hogg-Dube Syndrome - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Tumor Suppressor Proteins - genetics | Birt-Hogg-Dube Syndrome - etiology | Mice | Mitochondria | Cancer cells | Physiological aspects | Drug metabolism | Tumor suppressor genes | Estrone | Genetic aspects | Properties | Medical research | Muscular system | Metabolites | Kinases | Metabolic disorders | Index Medicus | Abridged Index Medicus
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4. Full Text Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
by Vincent, Emma E and Sergushichev, Alexey and Griss, Takla and Gingras, Marie-Claude and Samborska, Bozena and Ntimbane, Thierry and Coelho, Paula P and Blagih, Julianna and Raissi, Thomas C and Choinière, Luc and Bridon, Gaëlle and Loginicheva, Ekaterina and Flynn, Breanna R and Thomas, Elaine C and Tavaré, Jeremy M and Avizonis, Daina and Pause, Arnim and Elder, Douglas J.E and Artyomov, Maxim N and Jones, Russell G
Molecular cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 195 - 207
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Metabolomics | Cell Proliferation | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Glutamine - metabolism | Lung Neoplasms - pathology | Serine - biosynthesis | Neoplasms - genetics | Adaptation, Physiological - genetics | Pyruvic Acid - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Mitochondria - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Glucose - deficiency | Phosphoenolpyruvate - metabolism | Citric Acid Cycle - genetics | Animals | Gluconeogenesis - genetics | Mice, Nude | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Cell Line, Tumor | Purines - biosynthesis | Mice | Neoplasms - pathology | Phosphates | Glucose metabolism | Growth | Analysis | Physiological aspects | Glucose | Lung cancer, Non-small cell | Dextrose | Glutamine | Tumors | Resveratrol | Stress (Physiology) | Cancer | Index Medicus
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5. Full Text Functional annotation of rare gene aberration drivers of pancreatic cancer
by Tsang, Yiu Huen and Dogruluk, Turgut and Tedeschi, Philip M and Wardwell-Ozgo, Joanna and Lu, Hengyu and Espitia, Maribel and Nair, Nikitha and Minelli, Rosalba and Chong, Zechen and Chen, Fengju and Chang, Qing Edward and Dennison, Jennifer B and Dogruluk, Armel and Li, Min and Ying, Haoqiang and Bertino, Joseph R and Gingras, Marie-Claude and Ittmann, Michael and Kerrigan, John and Chen, Ken and Creighton, Chad J and Eterovic, Karina and Mills, Gordon B and Scott, Kenneth L
Nature communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, pp. 10500 - 10500
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pancreatic Neoplasms - metabolism | Reactive Oxygen Species - metabolism | Humans | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - enzymology | Pancreatic Neoplasms - genetics | Phosphotransferases (Alcohol Group Acceptor) - genetics | Carcinogenesis | Animals | Mice, Nude | Cell Line, Tumor | Female | Mice | Mutation | Index Medicus
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6. Full Text Genomic profiling guides the choice of molecular targeted therapy of pancreatic cancer
by Frank, Thomas S and Sun, Xiaotian and Zhang, Yuqing and Yang, Jingxuan and Fisher, William E and Gingras, Marie-Claude and Li, Min
Cancer letters, ISSN 0304-3835, 2015, Volume 363, Issue 1, pp. 1 - 6
Hematology, Oncology and Palliative Medicine | SLC39A4 (ZIP4) | Mutations | Gene therapy | Genomic profiling | Pancreatic cancer | Pharmacogenomics | Life Sciences & Biomedicine | Oncology | Science & Technology | Predictive Value of Tests | Genetic Predisposition to Disease | Pharmacogenetics | Pancreatic Neoplasms - metabolism | Humans | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Molecular Targeted Therapy | Patient Selection | Pancreatic Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Phenotype | Animals | Signal Transduction - drug effects | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - genetics | Genomics - methods | Precision Medicine | Care and treatment | Genetic aspects | Health aspects | Cancer | Index Medicus | genomic profiling | gene therapy | pancreatic cancer | mutations | pharmacogenomics
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7. Full Text Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome
by Campeau, Philippe M and Kim, Jaeseung C and Lu, James T and Schwartzentruber, Jeremy A and Abdul-Rahman, Omar A and Schlaubitz, Silke and Murdock, David M and Jiang, Ming-Ming and Lammer, Edward J and Enns, Gregory M and Rhead, William J and Rowland, Jon and Robertson, Stephen P and Cormier-Daire, Valérie and Bainbridge, Matthew N and Yang, Xiang-Jiao and Gingras, Marie-Claude and Gibbs, Richard A and Rosenblatt, David S and Majewski, Jacek and Lee, Brendan H
American journal of human genetics, ISSN 0002-9297, 02/2012, Volume 90, Issue 2, pp. 282 - 289
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Blepharoptosis - genetics | Blepharophimosis - enzymology | Humans | Urogenital Abnormalities - enzymology | Histone Acetyltransferases - genetics | Male | Bone Diseases, Developmental - genetics | Cerebellum - abnormalities | Intellectual Disability - genetics | Exome | Blepharophimosis - genetics | Heart Defects, Congenital - genetics | Rubinstein-Taybi Syndrome - genetics | Epigenomics - methods | Blepharoptosis - enzymology | Heart Defects, Congenital - enzymology | Intellectual Disability - enzymology | Female | Rubinstein-Taybi Syndrome - enzymology | Musculoskeletal Abnormalities - enzymology | Abnormalities, Multiple - genetics | Mice, Inbred C57BL | Phenotype | Animals | Bone Diseases, Developmental - enzymology | Musculoskeletal Abnormalities - genetics | Abnormalities, Multiple - enzymology | Heterozygote | Mice | Mutation | Sequence Analysis, DNA - methods | Urogenital Abnormalities - genetics | Brain | Dysplasia | Usage | Genetic disorders | Gene mutations | Exome sequencing | Physiological aspects | Causes of | Genetic aspects | Research | Histones | Analysis | Genomics | Proteins | Rodents | Epigenetics | Genetic research | Gene expression | Cells | Index Medicus | Report
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8. Full Text Whole-genome sequencing for optimized patient management
by Bainbridge, Matthew N and Wiszniewski, Wojciech and Murdock, David R and Friedman, Jennifer and Gonzaga-Jauregui, Claudia and Newsham, Irene and Reid, Jeffrey G and Fink, John K and Morgan, Margaret B and Gingras, Marie-Claude and Muzny, Donna M and Hoang, Linh D and Yousaf, Shahed and Lupski, James R and Gibbs, Richard A
Science translational medicine, ISSN 1946-6234, 06/2011, Volume 3, Issue 87, pp. 87re3 - 87re3
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Decision Making | Dystonic Disorders - genetics | Levodopa - therapeutic use | Humans | Male | Treatment Outcome | Sequence Analysis, DNA | Twins, Dizygotic - genetics | Dystonic Disorders - drug therapy | Patient Care | Pedigree | Adolescent | Female | Genome, Human | Index Medicus
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