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by Jaillette, Emmanuelle and Girault, Christophe and Brunin, Guillaume and Zerimech, Farid and Chiche, Arnaud and Broucqsault-Dedrie, Céline and Fayolle, Cyril and Minacori, Franck and Alves, Isabelle and Barrailler, Stephanie and Robriquet, Laurent and Delaporte, Emmanuel and Thellier, Damien and Delcourte, Claire and Duhamel, Alain and Nseir, Saad and Valette, Xavier and Desmeulles, Isabelle and Savary, Benoit and Masson, Romain and Seguin, Amélie and Daubin, Cédric and Sauneuf, Bertrand and Verrier, Pierre and Pottier, Véronique and Orabona, Marie and Samba, Désiré and Viquesnel, Gérald and Lermuzeaux, Mathilde and Hazera, Pascal and Hanouz, Jean-Luc and Parienti, Jean-Jacques and Du Cheyron, Damien and Demoule, Alexandre and Clavel, Marc and Rolland-Debord, Camille and Perbet, Sébastien and Terzi, Nicolas and Kouatchet, Achille and Wallet, Florent and Roze, Hadrien and Vargas, Frédéric and Guérin, Claude and Dellamonica, Jean and Jaber, Samir and Similowski, Thomas and Quenot, Jean-Pierre and Binquet, Christine and Vinsonneau, Christophe and Barbar, Saber-Davide and Vinault, Sandrine and Deckert, Valérie and Lemaire, Stephanie and Hssain, Ali Ait and Bruyère, Rémi and Souweine, Bertrand and Lagrost, Laurent and Adrie, Christophe and Jung, Boris and Daurat, Aurelien and De Jong, Audrey and Chanques, Gérald and Mahul, Martin and Monnin, Marion and Molinari, Nicolas and Lheureux, Olivier and Trepo, Eric and Hites, Maya and Cotton, Frederic and Wolff, Fleur and Surin, Rudy and Créteur, Jacques and Vincent, Jean-Louis and Gustot, Thierry and Jacobs, Frederique and Taccone, Fabio Silvio and Neuville, Mathilde and Timsit, Jean-François and El-Helali, Najoua and Le Monnier, Alban and Magalhaes, Eric and Radjou, Aguila and Smonig, Roland and Soubirou, Jean-François and Voiriot, Guillaume and Sonneville, Romain and Bouadma, Lila and Mourvillier, Bruno and Gélisse, Elodie and Brasseur, Alexandre and Roisin, Sandrine and De Backer, Daniel and Van Ruychevelt, Valerie and Carlier, Eric and Piagnerelli, Michael and Vanhaeverbeek, Michel and Danguy, Christine and Biston, Patrick and Au, Siu-Ming and Begot, Emmanuelle and ... and Qualité et Sécurité des Soins - CBPR-CFAR and Brain Liver Pitié-Salpêtrière Study Group (BLIPS), Paris, France and Working Group on Mechanical Ventilation and Outcomerea Study Group and COCOONs Study Group and Groupe ALIVE and For the GrrrOH: Groupe de recherche en réanimation respiratoire en Onco-Hématologie (Group for Research in Respiratory Intensive Care Onco-Hematology and EPURE Study Group and For the OUTCOMEREA Study Group and For the BIBLIOFLASH Study Group and Groupe de Recherche en Réanimation Respiratoire et Onco-Hematologique (GRRROH) and RETROMARS Study Group and BoReal study group and ABDOMIX Group and Groupe de travail sur la ventilation and Groupe de Recherche en Reanimation Respiratoire du patient d’Onc-hématologie and Groupe RMM and Université Paris 6 —Pierre et Marie Curie and Institut National pour la Santé et la Recherche Médicale, UMRS1158, Paris and Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie and ABLE French Investigators and ENCEPHALITICA Study Group and Septiflux trial Group and CRICS Network and OutcomeRéa and Committee of young intensivists of the French Society for Intensive Care Medicine (FICS) and NutriSIP and CNER DESC réanimation grand ouest and Phase Angle Project Investigators
Annals of Intensive Care, ISSN 2110-5820, 6/2016, Volume 6, Issue S1, pp. 1 - 236
PHYSICIANS ABSTRACTSO1 Impact of tracheal cuff shape on microaspiration of gastric contents in intubated critically ill patients: a multicenter randomized... 
Intensive / Critical Care Medicine | Emergency Medicine | Anesthesiology | Medicine & Public Health | Life Sciences | Human health and pathology
Journal Article
Diabetes Care, ISSN 0149-5992, 04/2011, Volume 34, Issue 4, pp. 813 - 817
Journal Article
by Schmidt, Manfred and Verhoeyen, Els and Gobbo, Emilie and Divers, Dominique and Oudrhiri, Noufissa and Griscelli, Frank and Bennaceur-Griscelli, Annelise and Klatzmann, David and Anguela, Xavier M and Sharma, Rajiv and Sharma, Rajiv and Li, Hojun and Li, Hojun and Haurigot, Virginia and Haurigot, Virginia and Haurigot, Virginia and Bhagwat, Anand and Bhagwat, Anand and Davidson, Robert and Davidson, Robert and Zhou, Shangzhen and Zhou, Shangzhen and Zhou, Shangzhen and Doyon, Yannick and Gregory, Philip D and Gregory, Philip D and Gregory, Philip D and Holmes, Michael C and Holmes, Michael C and Holmes, Michael C and High, Katherine A and Carbonaro, Denise and Shaw, Kit and Jin, Xiangyang and Geiger, Sabine and Mishra, Suparna and Cooper, Aaron and DeOliveira, Satiro and Sokolic, Rob and Candotti, Fabio and Carmo, Marlene and Arumugam, Paritha and Alonso-Ferrero, Maria and Schambach, Axel and Schambach, Axel and Baum, Christopher and Baum, Christopher and Baum, Christopher and Risma, Kimberly and Malik, Punam and Jordan, Michael and Rivat, Christine and Booth, Claire and Thrasher, Adrian and Whilding, Lynsey and Archibald, Kyra and Oberg, Daniel and Golan, Talia and Hubert, Ayala and Shemi, Amotz and Khvalevsky, Elina Zorde and Gabai-Malka, Racheli and Focht, Gili and Brunschwig, Zivia and Raskin, Stephen and Goldberg, Nahum and Ben-David, Eli and Peretz, Tamar and Eliakim, Rami and Dankur, Alan and Galun and Rachmur, Itzik and Domb, Avi and Kopelman, Yael and Hantz, Yael and Lahav, Mor and Arbel-Alon, Sagit and Dickson, George and Barkats, Martine and Daboussi, Fayza and Silva, Georges and Cedrone, Frederic and Epinat, Jean Charles and Juillerat, Alexandre and Valton, Julien and Montini, Eugenio and Biffi, Alessandra and Biffi, Alessandra and Calabria, Andrea and Calabria, Andrea and Biasco, Luca and Biasco, Luca and Cesani, Martina and Cesani, Martina and Benedicenti, Fabrizio and Benedicenti, Fabrizio and Plati, Tiziana and Leo, Simone and Zanetti, Gianluigi and Aiuti, Alessandro and ...
Human Gene Therapy, ISSN 1043-0342, 10/2012, Volume 23, Issue 10, pp. A1 - A173
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2013, Volume 9, Issue 3, pp. e1003211 - e1003211
Journal Article
by Kamilia, Chtara and Regaieg, Kais and Baccouch, Najeh and Chelly, Hedi and Bahloul, Mabrouk and Bouaziz, Mounir and Jendoubi, Ali and Abbes, Ahmed and Belhaouane, Houda and Nasri, Oussama and Jenzri, Layla and Ghedira, Salma and Houissa, Mohamed and Belkadi, Kamal and Harti, Youness and Nsiri, Afak and Khaleq, Khalid and Hamoudi, Driss and Harrar, Rachid and Thieffry, Camille and Wallet, Frédéric and Parmentier-Decrucq, Erika and Favory, Raphaël and Mathieu, Daniel and Poissy, Julien and Lafon, Thomas and Vignon, Philippe and Begot, Emmanuelle and Appert, Alexandra and Hadj, Mathilde and Claverie, Paul and Matt, Morgan and Barraud, Olivier and François, Bruno and Jamoussi, Amira and Jazia, Amira Ben and Marhbène, Takoua and Lakhdhar, Dhouha and Khelil, Jalila Ben and Besbes, Mohamed and Goutay, Julien and Blazejewski, Caroline and Joly-Durand, Isabelle and Pirlet, Isabelle and Weillaert, Marie Pierre and Beague, Sebastien and Aziz, Soufi and Hafiane, Reda and Hattabi, Khalid and Bouhouri, Mohamed Aziz and Hammoudi, Driss and Fadil, Abdelaziz and Harrar, Rachid Al and Zerouali, Khalid and Medhioub, Fatma Kaaniche and Allela, Rania and Algia, Najla Ben and Cherif, Samar and Slaoui, Mohamed Taoufik and Boubia, Souhail and Hafiani, Y and Khaoudi, A and Cherkab, R and Elallam, W and Elkettani, C and Barrou, L and Ridaii, M and Mehdi, Rihi El and Schimpf, Caroline and Mizrahi, Assaf and Pilmis, Benoît and Le Monnier, Alban and Tiercelet, Kelly and Cherin, Mélanie and Bruel, Cédric and Philippart, Francois and Bailly, Sébastien and Lucet, Jc and Lepape, Alain and L’hériteau, François and Aupée, Martine and Bervas, Caroline and Boussat, Sandrine and Berger-Carbonne, Anne and Machut, Anaïs and Savey, Anne and Timsit, Jean-François and Razazi, Keyvan and Rosman, Jérémy and de Prost, Nicolas and Carteaux, Guillaume and Jansen, Chloe and Decousser, Jean Winoc and Brun-Buisson, Christian and Dessap, Armand Mekontso and M’rad, Aymen and Ouali, Zouhour and Barghouth, Manel and Kouatchet, Achille and Mahieu, Rafael and ... and REA‑RAISIN Study group and Clinical Research in Intensive Care and Sepsis (CRICS network) and Sudden Death Expertise Center and OUTCOMEREA study group and Brain Liver Pitié-Salpêtrière Study Group (BLIPS) and for the HYPER2S Investigators and REVA research network and Cubrea network
Annals of Intensive Care, ISSN 2110-5820, 1/2017, Volume 7, Issue S1, pp. 105 - 207
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 105 - 109
In BRAF(V600)-mutant tumours, most mechanisms of resistance to drugs that target the BRAF and/or MEK kinases rely on reactivation of the RAS-RAF-MEK-ERK... 
MESSENGER-RNA TRANSLATION | SILVESTROL | MELANOMA | INITIATION | RAF | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | LEUKEMIA-CELLS | MODEL | FEEDBACK INHIBITION | Triterpenes - pharmacology | Humans | Eukaryotic Initiation Factor-4E - metabolism | Eukaryotic Initiation Factor-4G - metabolism | Eukaryotic Initiation Factor-4F - metabolism | Melanoma - genetics | Protein Binding - drug effects | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Phosphorylation - drug effects | Eukaryotic Initiation Factor-4F - antagonists & inhibitors | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Sulfonamides - pharmacology | Eukaryotic Initiation Factor-4A - antagonists & inhibitors | Drug Synergism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Eukaryotic Initiation Factor-4F - chemistry | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Melanoma - drug therapy | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Eukaryotic Initiation Factor-4A - metabolism | Drug Resistance, Neoplasm - drug effects | Thyroid Neoplasms - pathology | Antimitotic agents | Pharmaceutical research | Vemurafenib | Protein research | Research | Antineoplastic agents | Drug resistance | Phosphorylation | Biopsy | Melanoma | Mutation | Metastasis | Cancer therapies | Tumors | Cancer | Index Medicus | Cell and Molecular Biology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell- och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Computational Geosciences, ISSN 1420-0597, 07/2019, pp. 1 - 23
In this paper, we design and study a fully coupled numerical scheme for the poroelasticity problem modeled through Biot’s equations. The classical way to... 
Geomechanics | Approximation | Conservation equations | Computational fluid dynamics | Computer simulation | Conservation | Fluid flow | Finite volume method | Procedures | Equilibrium equations | Meshing | Equilibrium | Equations | Finite element method | Mathematical analysis | Volume | Modelling | Mathematical models | Nonlinear programming
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e46143 - e46143
T cell activation levels, viral load and CD4(+) T cell counts at early stages of HIV-1 infection are predictive of the rate of progression towards AIDS. We... 
VIRAL LOAD | DENDRITIC CELLS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | LYMPH-NODES | AFRICAN-GREEN MONKEYS | IMMUNE ACTIVATION | IMMUNODEFICIENCY VIRUS-INFECTION | SIV INFECTION | TYPE-1 INFECTION | I INTERFERON | Interleukin-18 - immunology | Humans | Middle Aged | Male | Young Adult | HIV Infections - immunology | Transforming Growth Factor beta1 - immunology | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | Time Factors | Chemokine CXCL10 - immunology | Adult | Female | Transforming Growth Factor beta1 - blood | Cytokines - blood | Cytokines - immunology | HIV Infections - blood | Inflammation Mediators - immunology | Chemokine CXCL10 - blood | Enzyme-Linked Immunosorbent Assay | Interleukin-18 - blood | HIV Infections - virology | Inflammation Mediators - blood | CD4 Lymphocyte Count | Biomarkers - blood | Viral Load - immunology | Disease Progression | HIV-1 - immunology | Adolescent | T-Lymphocytes - immunology | Aged | Cohort Studies | Virus diseases | Medical research | Medicine, Experimental | Development and progression | T cells | Transforming growth factors | HIV (Viruses) | Health aspects | Blood proteins | Antiretroviral drugs | Lymphatic system | Cytokines | Viremia | Lymphocytes T | Infections | Activation | Inflammation | T cell receptors | Interleukin 18 | CD4 antigen | Proteins | Studies | Cell activation | Plasma proteins | Immunology | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Biomarkers | IP-10 protein | Plasma levels | Bioindicators | Chemokines | Index Medicus | HIV Infections | HIV-1 | Viral Load | Life Sciences | Interleukin-18 | Inflammation Mediators | Transforming Growth Factor beta1 | T-Lymphocytes | Lymphocyte Activation | Chemokine CXCL10 | Virology | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2018, Volume 24, Issue 12, pp. 1877 - 1886
Preventing the immune escape of tumor cells by blocking inhibitory checkpoints, such as the interaction between programmed death ligand-1 (PD-L1) and... 
MEDICINE, RESEARCH & EXPERIMENTAL | RNA HELICASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENSITIVITY | BRAF | MICE LACKING | CELL BIOLOGY | ONCOGENIC RAS | RESISTANCE | PD-L1 | EIF4F | INHIBITOR | INITIATION COMPLEX | Tumor Escape - drug effects | Protein Biosynthesis | Humans | B7-H1 Antigen - therapeutic use | Eukaryotic Initiation Factor-4F - genetics | Gene Expression Regulation, Neoplastic - immunology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Melanoma - pathology | STAT1 Transcription Factor - genetics | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Animals | B7-H1 Antigen - antagonists & inhibitors | Signal Transduction - drug effects | Melanoma - genetics | Melanoma - immunology | Immunotherapy | Interferon-gamma - immunology | Cell Line, Tumor | Mice | Programmed Cell Death 1 Receptor - therapeutic use | Interferon-gamma - genetics | Melanoma - therapy | Tumor Escape - immunology | Prevention | Usage | Care and treatment | Analysis | Oncology, Experimental | Melanoma | Research | Biological response modifiers | Apoptosis | Cancer | RNA | Interferon | T cells | Genetic translation | Complex formation | PD-1 protein | Drug development | Immunosuppressive agents | Anticancer properties | DNA helicase | Antitumor agents | Bioindicators | Stat1 protein | Initiation complex | Translation | Tumor cells | Translation initiation | Pharmacology | Ribonucleic acid--RNA | Immune checkpoint | PD-L1 protein | Biomarkers | Antitumor activity | RNA helicase | Tumors | Index Medicus
Journal Article