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1. Full Text Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
by Gladyshev, Vadim N
Aging cell, ISSN 1474-9718, 08/2016, Volume 15, Issue 4, pp. 594 - 602
Aging | Evolution | Lifespan | Theories of aging | Deleteriome | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Environmental aspects | Stochastic processes | Analysis | Stochastic models | Index Medicus | Reviews | Review
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2. Full Text The Free Radical Theory of Aging Is Dead. Long Live the Damage Theory
by Gladyshev, Vadim N
Antioxidants & redox signaling, ISSN 1523-0864, 02/2014, Volume 20, Issue 4, pp. 727 - 731
Letter to the Editor | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Animals | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Oxidative Stress | Life Expectancy | Humans | Aging | Index Medicus
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3. Full Text Selenoproteins: Molecular pathways and physiological roles
by Labunskyy, Vyacheslav M and Hatfield, Dolph L and Gladyshev, Vadim N
Physiological reviews, ISSN 0031-9333, 07/2014, Volume 94, Issue 3, pp. 739 - 777
Life Sciences & Biomedicine | Physiology | Science & Technology | Organoselenium Compounds | Animals | Selenium - metabolism | Selenoproteins - physiology | Dipeptides - biosynthesis | Humans | Physiological aspects | Physiology, Pathological | Selenoproteins | Research | Proteins | Molecules | Selenium | Prokaryotes | Knowledge | Index Medicus | Reviews
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4. Full Text The Ground Zero of Organismal Life and Aging
by Gladyshev, Vadim N
Trends in molecular medicine, ISSN 1471-4914, 01/2021, Volume 27, Issue 1, pp. 11 - 19
development | ground zero | aging | biological age | rejuvenation | lifespan | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Telomeres | Analysis | Stem cells | Index Medicus
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5. Full Text The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan
by Gladyshev, Vadim N
Trends in genetics, ISSN 0168-9525, 2013, Volume 29, Issue 9, pp. 506 - 512
Medical Education | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Biological Evolution | Aging - genetics | Aging - physiology | DNA Damage - physiology | Models, Biological | Humans | Oxidative Stress - genetics | Selection, Genetic | Genome, Human | Longevity - physiology | Genomics | Analysis | Index Medicus
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6. Full Text Translation inhibitors cause abnormalities in ribosome profiling experiments
by Gerashchenko, Maxim V and Gerashchenko, Maxim V and Gladyshev, Vadim N and Gladyshev, Vadim N
Nucleic acids research, ISSN 0305-1048, 2014, Volume 42, Issue 17, pp. e134 - e134
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Saccharomyces cerevisiae - genetics | Oxidative Stress - genetics | Ribosomes - metabolism | Saccharomyces cerevisiae - drug effects | RNA, Messenger - metabolism | Cycloheximide - pharmacology | Heat-Shock Response - genetics | Artifacts | Sequence Analysis, RNA | Ribosomes - drug effects | Protein Biosynthesis - drug effects | RNA, Messenger - chemistry | High-Throughput Nucleotide Sequencing | Protein Synthesis Inhibitors - pharmacology | Index Medicus | Methods Online
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7. Full Text Molecular signatures of longevity: Insights from cross-species comparative studies
by Ma, Siming and Gladyshev, Vadim N
Seminars in cell & developmental biology, ISSN 1084-9521, 10/2017, Volume 70, pp. 190 - 203
Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | TOR Serine-Threonine Kinases - metabolism | Caloric Restriction | Longevity - drug effects | Humans | Transcriptome | Insulin-Like Growth Factor I - genetics | Bowhead Whale - metabolism | TOR Serine-Threonine Kinases - genetics | Chiroptera - metabolism | Gene Expression Regulation, Developmental | Killifishes - genetics | Chiroptera - growth & development | Methionine - deficiency | Bowhead Whale - growth & development | Metformin - pharmacology | Metabolome | Killifishes - metabolism | Longevity - genetics | Sirolimus - pharmacology | Mole Rats - metabolism | Bowhead Whale - genetics | Animals | Mole Rats - genetics | Killifishes - growth & development | Genome | Mole Rats - growth & development | Chiroptera - genetics | Insulin-Like Growth Factor I - metabolism | Metabolites | Comparative analysis | Gene expression | Genomics | Index Medicus
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8. Full Text Regulated methionine oxidation by monooxygenases
by Manta, Bruno and Gladyshev, Vadim N
Free radical biology & medicine, ISSN 0891-5849, 08/2017, Volume 109, pp. 141 - 155
Scaffolding proteins | DUF3585 | Methionine sulfoxide | Actin | Methionine | Methionine sulfoxide reductase | MICAL | Monooxygenase | Redox signaling | Methionine oxidation | Multidomain proteins | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Adaptor Proteins, Signal Transducing - chemistry | Reactive Oxygen Species - metabolism | Cytoskeletal Proteins - genetics | Humans | Isoenzymes - chemistry | Methionine Sulfoxide Reductases - genetics | LIM Domain Proteins - metabolism | Isoenzymes - metabolism | Protein Domains | Cytoskeletal Proteins - metabolism | Cysteine - metabolism | NADP - metabolism | LIM Domain Proteins - chemistry | Oxidation-Reduction | Protein Structure, Secondary | Isoenzymes - genetics | Methionine - metabolism | Models, Molecular | Cytoskeletal Proteins - chemistry | Methionine Sulfoxide Reductases - metabolism | Animals | Methionine - chemistry | Adaptor Proteins, Signal Transducing - genetics | LIM Domain Proteins - genetics | Protein Processing, Post-Translational | Kinetics | Adaptor Proteins, Signal Transducing - metabolism | Enzymes | Oxidation-reduction reaction | Cysteine | Proteins | Stem cells | Cystine | Protein binding | Index Medicus | methionine oxidation | actin | redox signaling | methionine sulfoxide reductase | methionine | multidomain proteins | scaffolding proteins | methionine sulfoxide | monooxygenase
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