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eLife, ISSN 2050-084X, 11/2019, Volume 8
Intracellular trafficking depends on the function of Rab GTPases, whose activation is regulated by guanine exchange factors (GEFs). The Rab5 GEF, Rabex5, was... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2016, Volume 113, Issue 30, p. E4357
  Leucine-rich repeat kinase 2 (LRRK2) is a large, multidomain protein containing two catalytic domains: a Ras of complex proteins (Roc) G-domain and a kinase... 
Proteins | Pathogenesis | Parkinsons disease | Mutation | Kinases
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 01/2014, Volume 111, Issue 1, pp. E34 - E34
Leucine-rich repeat kinase 2 (LRRK2) is a multidomain protein implicated in Parkinson disease (PD); however, the molecular mechanism and mode of action of this... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2014, Volume 111, Issue 1, pp. 11 - 11
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2014, Volume 111, Issue 1, p. E34
  Leucine-rich repeat kinase 2 (LRRK2) is a multidomain protein implicated in Parkinson disease (PD); however, the molecular mechanism and mode of action of... 
Proteins | Phosphorylation | Mutagenesis | Pathogenesis | Parkinsons disease | Mutation | Kinases
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e111632
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 6, pp. 2225 - 2237
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the single most common cause of inherited Parkinson's disease. Little is known about its involvement in... 
MOTOR-NERVE TERMINALS | CLATHRIN-MEDIATED ENDOCYTOSIS | READILY RELEASABLE POOL | PAIRED-PULSE DEPRESSION | REPEAT KINASE 2 | NEUROTRANSMITTER RELEASE | SINGLE-PARTICLE TRACKING | NEUROSCIENCES | CULTURED HIPPOCAMPAL-NEURONS | SHORT-TERM | PARKINSONS-DISEASE | N-Ethylmaleimide-Sensitive Proteins - metabolism | Calcium - metabolism | Embryo, Mammalian | Humans | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Protein Transport - drug effects | Synaptosomes - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Cerebral Cortex - ultrastructure | Excitatory Postsynaptic Potentials - physiology | Transfection - methods | Potassium Chloride - pharmacology | Tetrodotoxin - pharmacology | Electric Stimulation - methods | Synaptic Vesicles - physiology | Tandem Mass Spectrometry - methods | Microscopy, Electron, Transmission | Immunoprecipitation - methods | Synaptic Vesicles - ultrastructure | Protein-Serine-Threonine Kinases - physiology | RNA, Small Interfering - pharmacology | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Sodium Channel Blockers - pharmacology | Synapses - ultrastructure | Mutation - genetics | Protein Transport - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Nerve Tissue Proteins - metabolism | Animals | Analysis of Variance | Synaptic Vesicles - drug effects | Mice
Journal Article
Nature Communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 11491
Journal Article
Journal Article
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