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Tetrahedron Letters, ISSN 0040-4039, 09/2019, Volume 60, Issue 39, p. 151078
The benzimidazole-2-thione scaffold is present in many drugs encompassing various therapeutic areas. Due to the broad spectrum of bioactivities it also... 
2-Mercaptobenzimidazole | Benzimidazole-2-thione | Regioisomerism | NOESY | Fragments in drug discovery | HMBC
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 04/2019, Volume 24, Issue 7, p. 1261
Despite the great importance of β-lactam antibiotics, there is still a limited number of synthetic approaches for the formation of β-lactam⁻containing... 
Anti-Bacterial Agents - chemical synthesis | Peptide Fragments - chemical synthesis | Molecular Structure | Heterocyclic Compounds, 1-Ring - chemistry | beta-Lactams - chemical synthesis | dibenzylamino | pseudopeptides | β-lactams | nocardicin | Mitsunobu reaction
Journal Article
Drug Development Research, ISSN 0272-4391, 02/2019, Volume 80, Issue 1, pp. 6 - 10
The increase of antimicrobial resistance necessitates the renewal and strong research involvement in antibacterial drug design. In the following work, we... 
antibacterial | MurA | Mur ligases | MurB | antimicrobial resistance | drug design | CHEMISTRY, MEDICINAL | CHALLENGES | CELL-WALL | EFFLUX | MURA ENZYME | BIOSYNTHESIS | RESISTANCE | PHARMACOLOGY & PHARMACY | INHIBITORS | STEPS | Drug resistance in microorganisms | Ligases | Antibacterial agents | Enzymes | Antimicrobial resistance | Drug development | Therapeutic applications | Antibacterial materials
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 02/2016, Volume 23, Issue 5, pp. 464 - 482
Expanding antibiotic use in clinical practice and emergence of bacterial resistance are fueling research efforts for the development of novel antibacterials.... 
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 12/2017, Volume 57, Issue 12, p. 3094
Identification of conserved waters in protein structures is a challenging task with applications in molecular docking and protein stability prediction. As an... 
Water | Drugs | Queries | Water chemistry | Data banks | Computer simulation | Conservation | Water conservation | Molecular docking | Proteins | Molecules | Algorithms | Simulation | Binding sites
Journal Article
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 03/2018, Volume 38, Issue 2, pp. 426 - 503
Journal Article
MOLECULES, ISSN 1420-3049, 07/2019, Volume 24, Issue 14, p. 2590
Large-scale virtual screening of boronic acid derivatives was performed to identify nonpeptidic covalent inhibitors of the beta 5i subunit of the... 
immunoproteasome | beta 5i selective inhibitor | virtual screening | covalent inhibitor | DOCKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | PROTEASOME | CHEMISTRY, MULTIDISCIPLINARY | SUBUNIT | β5i selective inhibitor
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, p. 39495
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2018, Volume 24, Issue 57, pp. 15254 - 15266
Journal Article