Digestive Endoscopy, ISSN 0915-5635, 10/2019
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2010, Volume 28, Issue 9, pp. 1566 - 1572
Purpose Most of the esophageal squamous cell carcinomas (ESCCs) and cancers of the head and neck (H&N) region are diagnosed at later stages. To achieve better...
SYSTEM | DIAGNOSIS | ENDOSCOPIC MUCOSAL RESECTION | RISK-FACTORS | ONCOLOGY | GASTRIC-CANCER | JAPANESE | BARRETTS-ESOPHAGUS | MAGNIFYING ENDOSCOPY | IN-SITU | LESIONS | Oropharyngeal Neoplasms - diagnosis | Optical Devices | Early Detection of Cancer - methods | Image Enhancement | Humans | Middle Aged | Endoscopy - methods | Male | Carcinoma, Squamous Cell - diagnosis | Precancerous Conditions - diagnosis | Hypopharyngeal Neoplasms - diagnosis | Aged, 80 and over | Adult | Esophageal Neoplasms - diagnosis | Female | Head and Neck Neoplasms - diagnosis | Aged | Original Reports | Gic9 | Dxst | Hnc2
SYSTEM | DIAGNOSIS | ENDOSCOPIC MUCOSAL RESECTION | RISK-FACTORS | ONCOLOGY | GASTRIC-CANCER | JAPANESE | BARRETTS-ESOPHAGUS | MAGNIFYING ENDOSCOPY | IN-SITU | LESIONS | Oropharyngeal Neoplasms - diagnosis | Optical Devices | Early Detection of Cancer - methods | Image Enhancement | Humans | Middle Aged | Endoscopy - methods | Male | Carcinoma, Squamous Cell - diagnosis | Precancerous Conditions - diagnosis | Hypopharyngeal Neoplasms - diagnosis | Aged, 80 and over | Adult | Esophageal Neoplasms - diagnosis | Female | Head and Neck Neoplasms - diagnosis | Aged | Original Reports | Gic9 | Dxst | Hnc2
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 171, Issue 1, pp. 33 - 39
Background Detailed characteristics of patients with acute heart failure (AHF) in Japan have not been elucidated. Furthermore, international application of...
Cardiovascular | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | PREDICTING MORTALITY | MODELS | EJECTION FRACTION | COHORT | IN-HOSPITAL MORTALITY | ASSOCIATION | STRATIFICATION | EPIDEMIOLOGY | Severity of Illness Index | Japan - epidemiology | Risk Assessment - methods | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Heart Failure - blood | Disease Progression | Hospital Mortality - trends | Young Adult | Guideline Adherence | Aged, 80 and over | Adult | Female | Registries | Aged | Heart Failure - diagnosis | Natriuretic Peptide, Brain - blood | Heart Failure - mortality | Heart failure | Cardiac patients | Risk factors | Natriuretic peptides | Cardiomyopathy | Mortality | Hospitalization | Family medical history | Patients | Studies | Heart rate | Body mass index | Discrimination | Biomarkers | Chronic obstructive pulmonary disease | Clinical medicine | Cardiology | Acute coronary syndromes | Logistics
Cardiovascular | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | PREDICTING MORTALITY | MODELS | EJECTION FRACTION | COHORT | IN-HOSPITAL MORTALITY | ASSOCIATION | STRATIFICATION | EPIDEMIOLOGY | Severity of Illness Index | Japan - epidemiology | Risk Assessment - methods | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Heart Failure - blood | Disease Progression | Hospital Mortality - trends | Young Adult | Guideline Adherence | Aged, 80 and over | Adult | Female | Registries | Aged | Heart Failure - diagnosis | Natriuretic Peptide, Brain - blood | Heart Failure - mortality | Heart failure | Cardiac patients | Risk factors | Natriuretic peptides | Cardiomyopathy | Mortality | Hospitalization | Family medical history | Patients | Studies | Heart rate | Body mass index | Discrimination | Biomarkers | Chronic obstructive pulmonary disease | Clinical medicine | Cardiology | Acute coronary syndromes | Logistics
Journal Article
Nature Protocols, ISSN 1754-2189, 07/2018, Volume 13, Issue 7, pp. 1603 - 1631
The ability to rapidly assay morphological and intracellular molecular variations within large heterogeneous populations of cells is essential for...
LABEL-FREE | SINGLE-CELL | CONFOCAL MICROSCOPY | FLUORESCENCE MICROSCOPY | OPTICAL COHERENCE TOMOGRAPHY | LASER | PERFORMANCE | BIOCHEMICAL RESEARCH METHODS | CLASSIFICATION | ENCODED AMPLIFIED MICROSCOPY | MICROFLUIDICS | Flow cytometry | Green development | Image processing | Materials handling | Algae | Data processing | Optics | Molecular chains | Image acquisition | Learning algorithms | Image analysis | Sample preparation | Data management | Microscopy | Computer applications | Machine learning | Digital signal processing | Information processing | Green aspects | Software | Clean energy | Microfluidics | Image enhancement
LABEL-FREE | SINGLE-CELL | CONFOCAL MICROSCOPY | FLUORESCENCE MICROSCOPY | OPTICAL COHERENCE TOMOGRAPHY | LASER | PERFORMANCE | BIOCHEMICAL RESEARCH METHODS | CLASSIFICATION | ENCODED AMPLIFIED MICROSCOPY | MICROFLUIDICS | Flow cytometry | Green development | Image processing | Materials handling | Algae | Data processing | Optics | Molecular chains | Image acquisition | Learning algorithms | Image analysis | Sample preparation | Data management | Microscopy | Computer applications | Machine learning | Digital signal processing | Information processing | Green aspects | Software | Clean energy | Microfluidics | Image enhancement
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 9
Abstract While immunomodulators (IMs) are used as key drugs in remission maintenance treatment for ulcerative colitis (UC), there has been no evidence to date...
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2010, Volume 7, Issue 3, pp. 391 - 402
Hematopoietic stem cells (HSCs) are sustained in a specific microenvironment known as the stem cell niche. Mammalian HSCs are kept quiescent in the endosteal...
STEMCELL | PROGENITOR CELLS | MAINTENANCE | BONE-MARROW | QUIESCENCE | NICHE | RESIDE | HYPOXIA | BMI1 | EXPRESSION | CYCLE | CELL & TISSUE ENGINEERING | CELL BIOLOGY
STEMCELL | PROGENITOR CELLS | MAINTENANCE | BONE-MARROW | QUIESCENCE | NICHE | RESIDE | HYPOXIA | BMI1 | EXPRESSION | CYCLE | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Cell Stem Cell, ISSN 1934-5909, 01/2013, Volume 12, Issue 1, pp. 49 - 61
Defining the metabolic programs that underlie stem cell maintenance will be essential for developing strategies to manipulate stem cell capacity. Mammalian...
HOMEOSTASIS | DYE EFFLUX | BONE-MARROW | KINASE | GROWTH | HYPOXIC-NICHE | SELF-RENEWAL | INHIBITOR | CANCER | PYRUVATE-DEHYDROGENASE COMPLEX | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Immunohistochemistry | Cell Cycle - genetics | Reactive Oxygen Species - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Hematopoietic Stem Cells - metabolism | Glycolysis - genetics | Glycolysis - physiology | Animals | Flow Cytometry | Mice, Mutant Strains | Models, Biological | Cell Cycle - physiology | Mice | Protein-Serine-Threonine Kinases - metabolism | Medicin och hälsovetenskap | Medicinsk bioteknologi (inriktn. mot cellbiologi (inkl. stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
HOMEOSTASIS | DYE EFFLUX | BONE-MARROW | KINASE | GROWTH | HYPOXIC-NICHE | SELF-RENEWAL | INHIBITOR | CANCER | PYRUVATE-DEHYDROGENASE COMPLEX | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Immunohistochemistry | Cell Cycle - genetics | Reactive Oxygen Species - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Hematopoietic Stem Cells - metabolism | Glycolysis - genetics | Glycolysis - physiology | Animals | Flow Cytometry | Mice, Mutant Strains | Models, Biological | Cell Cycle - physiology | Mice | Protein-Serine-Threonine Kinases - metabolism | Medicin och hälsovetenskap | Medicinsk bioteknologi (inriktn. mot cellbiologi (inkl. stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
The American Journal of Cardiology, ISSN 0002-9149, 03/2018, Volume 121, Issue 6, pp. 731 - 738
Plasma B-type natriuretic peptide (BNP) is an important prognostic marker in patients with acute heart failure (AHF). However, it is unclear which BNP...
DISCHARGE | MORTALITY | 2013 ACCF/AHA GUIDELINE | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | ADMISSION | AMERICAN-COLLEGE | CLINICAL PROFILE | ASSOCIATION TASK-FORCE | OUTCOMES | Predictive Value of Tests | Prognosis | Humans | Japan | Heart Failure - physiopathology | Stroke Volume - physiology | Male | Biomarkers - blood | Heart Failure - blood | Phenotype | Female | Registries | Aged | Retrospective Studies | Natriuretic Peptide, Brain - blood | Heart failure | Brain natriuretic peptide | Plasma | Phenotypes | Statistical analysis | Peptides | Mortality | Performance prediction | Patients | Beta blockers | Discharge | Confidence intervals | Studies | Population | Ventricle | Health risk assessment | Heart diseases | Ejection
DISCHARGE | MORTALITY | 2013 ACCF/AHA GUIDELINE | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | ADMISSION | AMERICAN-COLLEGE | CLINICAL PROFILE | ASSOCIATION TASK-FORCE | OUTCOMES | Predictive Value of Tests | Prognosis | Humans | Japan | Heart Failure - physiopathology | Stroke Volume - physiology | Male | Biomarkers - blood | Heart Failure - blood | Phenotype | Female | Registries | Aged | Retrospective Studies | Natriuretic Peptide, Brain - blood | Heart failure | Brain natriuretic peptide | Plasma | Phenotypes | Statistical analysis | Peptides | Mortality | Performance prediction | Patients | Beta blockers | Discharge | Confidence intervals | Studies | Population | Ventricle | Health risk assessment | Heart diseases | Ejection
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0176718
Sanitation of environmental surfaces with chlorine based-disinfectants is a principal measure to control outbreaks of norovirus or Clostridium difficile. The...
SANITIZERS | SODIUM-CHLORITE | ESCHERICHIA-COLI O157-H7 | GLUTATHIONE | MULTIDISCIPLINARY SCIENCES | CHLORINE DIOXIDE | CONTAMINATION | DISINFECTION | NOSOCOMIAL PATHOGENS | NOROVIRUS | SURFACES | Cats | Animals | Calicivirus, Feline - drug effects | Chlorides - pharmacology | Humans | Rats | Spores, Bacterial - drug effects | Clostridium difficile - growth & development | Serum Albumin, Bovine - metabolism | Thiosulfates - pharmacology | Spectrophotometry, Ultraviolet | Clostridium difficile - drug effects | Physiological aspects | Anti-infective agents | Research | Clostridium difficile | Drinking water | Organic matter | Sanitation | Surface chemistry | Sodium hypochlorite | Acidification | Outbreaks | Antiinfectives and antibacterials | Spores | Meat | Microorganisms | Microbicides | Restoration | Disinfectants | Medical personnel | Pathogens | Bovine serum albumin | Food contamination & poisoning | Chlorine | Serum albumin | Contamination | Medicine | Infectious diseases | Acids | Sodium | Thiosulfate | Disinfection & disinfectants | Sodium thiosulfate | Methods | Neutralization
SANITIZERS | SODIUM-CHLORITE | ESCHERICHIA-COLI O157-H7 | GLUTATHIONE | MULTIDISCIPLINARY SCIENCES | CHLORINE DIOXIDE | CONTAMINATION | DISINFECTION | NOSOCOMIAL PATHOGENS | NOROVIRUS | SURFACES | Cats | Animals | Calicivirus, Feline - drug effects | Chlorides - pharmacology | Humans | Rats | Spores, Bacterial - drug effects | Clostridium difficile - growth & development | Serum Albumin, Bovine - metabolism | Thiosulfates - pharmacology | Spectrophotometry, Ultraviolet | Clostridium difficile - drug effects | Physiological aspects | Anti-infective agents | Research | Clostridium difficile | Drinking water | Organic matter | Sanitation | Surface chemistry | Sodium hypochlorite | Acidification | Outbreaks | Antiinfectives and antibacterials | Spores | Meat | Microorganisms | Microbicides | Restoration | Disinfectants | Medical personnel | Pathogens | Bovine serum albumin | Food contamination & poisoning | Chlorine | Serum albumin | Contamination | Medicine | Infectious diseases | Acids | Sodium | Thiosulfate | Disinfection & disinfectants | Sodium thiosulfate | Methods | Neutralization
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2018, Volume 128, Issue 12, pp. 5603 - 5619
The agonistic/antagonistic biocharacter of selective estrogen receptor modulators (SERMs) can have therapeutic advantages, particularly in the case of...
INTERNATIONAL EXPERT CONSENSUS | TISSUE-SPECIFICITY | MEDICINE, RESEARCH & EXPERIMENTAL | PRIMARY THERAPY | ACTIVATION | PROMOTER-CONTEXT | TAMOXIFEN RESISTANCE | COACTIVATOR AIB1 | COMPLEXES | HISTONE DEMETHYLASE JMJD2B | ALPHA | Care and treatment | Receptors | Breast cancer | Research | Cases | Steroid hormones | Phenols | Hostages | Menopause | Estrogen | Senescence | Therapeutic applications | F-box protein | Estrogen receptors | Cardiovascular disease | Tamoxifen | Src protein | ErbB-2 protein | Signal transduction | Enhancers | Androgens | Epidermal growth factor | Lysine | Transcription activation | DNA methylation | Ligands | Selective estrogen receptor modulators | Deoxyribonucleic acid--DNA
INTERNATIONAL EXPERT CONSENSUS | TISSUE-SPECIFICITY | MEDICINE, RESEARCH & EXPERIMENTAL | PRIMARY THERAPY | ACTIVATION | PROMOTER-CONTEXT | TAMOXIFEN RESISTANCE | COACTIVATOR AIB1 | COMPLEXES | HISTONE DEMETHYLASE JMJD2B | ALPHA | Care and treatment | Receptors | Breast cancer | Research | Cases | Steroid hormones | Phenols | Hostages | Menopause | Estrogen | Senescence | Therapeutic applications | F-box protein | Estrogen receptors | Cardiovascular disease | Tamoxifen | Src protein | ErbB-2 protein | Signal transduction | Enhancers | Androgens | Epidermal growth factor | Lysine | Transcription activation | DNA methylation | Ligands | Selective estrogen receptor modulators | Deoxyribonucleic acid--DNA
Journal Article
Heart and Vessels, ISSN 0910-8327, 11/2019, Volume 34, Issue 11, pp. 1777 - 1788
Heart failure (HF) is characterized by frequent rehospitalization and prolonged hospital stay. Although length of stay has been used as a surrogate marker for...
Heart failure | Medicine & Public Health | Cardiac Surgery | Vascular Surgery | Readmission | Registry-based study | Cardiology | Biomedical Engineering and Bioengineering | Length of stay | Confidence intervals | Patients | Heart diseases | Discharge
Heart failure | Medicine & Public Health | Cardiac Surgery | Vascular Surgery | Readmission | Registry-based study | Cardiology | Biomedical Engineering and Bioengineering | Length of stay | Confidence intervals | Patients | Heart diseases | Discharge
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 11, pp. 947 - 947
 Background: Predictive models for heart failure patients such as the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) score is used widely to...
Cardiovascular | Internal Medicine | Heart failure | Medical colleges | Cardiac patients | Risk factors | Calibration | Beta blockers | Patients | Mortality
Cardiovascular | Internal Medicine | Heart failure | Medical colleges | Cardiac patients | Risk factors | Calibration | Beta blockers | Patients | Mortality
Journal Article
Nature Protocols, ISSN 1754-2189, 11/2019, Volume 14, Issue 11, pp. 3273 - 3273
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Journal Article
NATURE PROTOCOLS, ISSN 1754-2189, 08/2019, Volume 14, Issue 8, pp. 2370 - 2415
Intelligent image-activated cell sorting (iIACS) is a machine-intelligence technology that performs real-time intelligent image-based sorting of single cells...
SPEED | SINGLE-CELL | LABEL-FREE | HIGH-THROUGHPUT | BIOCHEMICAL RESEARCH METHODS | TIME-STRETCH | FLOW-CYTOMETRY | MICROSCOPY | TRANSCRIPTION FACTOR | REVEALS | BLOOD | Flow cytometry | Mechatronics | Design parameters | Integration | Data acquisition | Decision making | Mechanical properties | Fluorescence | Actuation | Data processing | Optics | Parameter sensitivity | Real time operation | Gene sequencing | Image quality | Organic chemistry | Mechanical components | Data management | Microscopy | Computer applications | Machine learning | Digital signal processing | Information processing | Microfluidics
SPEED | SINGLE-CELL | LABEL-FREE | HIGH-THROUGHPUT | BIOCHEMICAL RESEARCH METHODS | TIME-STRETCH | FLOW-CYTOMETRY | MICROSCOPY | TRANSCRIPTION FACTOR | REVEALS | BLOOD | Flow cytometry | Mechatronics | Design parameters | Integration | Data acquisition | Decision making | Mechanical properties | Fluorescence | Actuation | Data processing | Optics | Parameter sensitivity | Real time operation | Gene sequencing | Image quality | Organic chemistry | Mechanical components | Data management | Microscopy | Computer applications | Machine learning | Digital signal processing | Information processing | Microfluidics
Journal Article
Circulation Journal, ISSN 1346-9843, 2017, Volume 81, Issue 7, pp. 966 - 973
Background:Although obesity is associated with left ventricular hypertrophy, diastolic dysfunction, and occurrence of atrial fibrillation (AF), obese heart...
Heart failure | Obesity paradox | Body mass index | Atrial fibrillation | VENTRICULAR SYSTOLIC DYSFUNCTION | MORTALITY | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | MORBIDITY | COMMUNITY | CARDIAC CACHEXIA | BODY-MASS INDEX | OUTCOMES | Follow-Up Studies | Patient Readmission | Obesity - complications | Atrial Fibrillation - therapy | Humans | Middle Aged | Heart Failure - physiopathology | Male | Obesity - physiopathology | Atrial Fibrillation - physiopathology | Stroke Volume | Heart Failure - therapy | Atrial Fibrillation - mortality | Obesity - therapy | Aged, 80 and over | Atrial Fibrillation - etiology | Female | Registries | Aged | Obesity - mortality | Heart Failure - etiology | Heart Failure - mortality
Heart failure | Obesity paradox | Body mass index | Atrial fibrillation | VENTRICULAR SYSTOLIC DYSFUNCTION | MORTALITY | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | MORBIDITY | COMMUNITY | CARDIAC CACHEXIA | BODY-MASS INDEX | OUTCOMES | Follow-Up Studies | Patient Readmission | Obesity - complications | Atrial Fibrillation - therapy | Humans | Middle Aged | Heart Failure - physiopathology | Male | Obesity - physiopathology | Atrial Fibrillation - physiopathology | Stroke Volume | Heart Failure - therapy | Atrial Fibrillation - mortality | Obesity - therapy | Aged, 80 and over | Atrial Fibrillation - etiology | Female | Registries | Aged | Obesity - mortality | Heart Failure - etiology | Heart Failure - mortality
Journal Article