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1. Full Text Nimbolide ameliorates pancreatic inflammation and apoptosis by modulating NF-κB/SIRT1 and apoptosis signaling in acute pancreatitis model
by Bansod, Sapana and Godugu, Chandraiah
International immunopharmacology, ISSN 1567-5769, 01/2021, Volume 90, pp. 107246 - 107246
Acute pancreatitis (AP) | Nimbolide (NB) | Inflammation | SIRT1 | Apoptosis | Index Medicus
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2. Full Text Inhibition of lysyl oxidase ameliorates renal injury by inhibiting CD44-mediated pericyte detachment and loss of peritubular capillaries
by Saifi, Mohd Aslam and Godugu, Chandraiah
Life sciences (1973), ISSN 0024-3205, 02/2020, Volume 243, pp. 117294 - 117294
Peritubular capillaries | Pericytes | Chronic kidney disease | Lysyl oxidase | Renal fibrosis | CD44 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Kidney - blood supply | Capillaries - pathology | Kidney - pathology | Male | Ureteral Obstruction - metabolism | Collagen - metabolism | Protein-Lysine 6-Oxidase - antagonists & inhibitors | Kidney - metabolism | Animals | Pericytes - pathology | Ureteral Obstruction - pathology | Epithelial-Mesenchymal Transition | Fibrosis | Hyaluronan Receptors - metabolism | Aminopropionitrile - pharmacology | Mice | Catalysis | Animal models | Kidneys | Oxidase | Collagens | Crosslinking | Rarefaction | Reduction | Etiology | CD44 antigen | Liquid oxygen | Collagen | Extracellular matrix | Oxidation | Microvasculature | Kidney diseases | Inhibition | Capillaries | Deposition | Index Medicus
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3. Full Text The current understanding and potential therapeutic options to combat COVID-19
by Pooladanda, Venkatesh and Thatikonda, Sowjanya and Godugu, Chandraiah
Life sciences (1973), ISSN 0024-3205, 08/2020, Volume 254, pp. 117765 - 19
COVID-19 | Zoonotic origin | SARS-CoV-2 | Repurposing drugs | Spike proteins | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Betacoronavirus - isolation & purification | Pneumonia, Viral - therapy | Pandemics - prevention & control | Zoonoses - therapy | Zoonoses - virology | Animals | Coronavirus Infections - epidemiology | Coronavirus Infections - virology | Pneumonia, Viral - epidemiology | Coronavirus Infections - therapy | Zoonoses - epidemiology | Pneumonia, Viral - virology | Drugs | Pandemics | Health services | Viral diseases | Seafood | Viruses | Genomes | Vaccines | Human immunodeficiency virus--HIV | Pathogens | Signs and symptoms | Spike protein | Severe acute respiratory syndrome | Coronaviruses | Ribonucleic acid--RNA | Zoonoses | Severe acute respiratory syndrome coronavirus 2 | Pathogenicity | Replication origins | Disease transmission | Respiratory diseases | Stem cells | Monoclonal antibodies | Replication | Antiparasitic agents | Interferon | Index Medicus
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4. A review on pharmacological properties of coumarins
by Srikrishna, Devulapally and Godugu, Chandraiah and Kumar Dubey, Pramod
Mini reviews in medicinal chemistry, ISSN 1389-5575, 2016, Volume 16, Issue 2, pp. 113 - 141
Antimicrobial | Pharmacological properties | Anticonvulsant | Anticancer | Antioxidant | Anti-inflammatory | Coumarin | MAO inhibitory | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Anti-HIV Agents - pharmacology | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Anti-Infective Agents - pharmacology | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Coumarins - chemistry | Monoamine Oxidase Inhibitors - chemical synthesis | Anti-HIV Agents - chemical synthesis | Anticonvulsants - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Anti-Infective Agents - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Monoamine Oxidase Inhibitors - pharmacology | Antineoplastic Agents, Phytogenic - chemical synthesis | Anticonvulsants - chemical synthesis | Antitubercular Agents - pharmacology | Antineoplastic Agents, Phytogenic - chemistry | Anti-Infective Agents - chemical synthesis | Coumarins - pharmacology | Anti-HIV Agents - chemistry | Animals | Anticonvulsants - chemistry | Coumarins - chemical synthesis | Monoamine Oxidase Inhibitors - chemistry | Antineoplastic Agents, Phytogenic - pharmacology
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5. Full Text Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation
by Thatikonda, Sowjanya and Pooladanda, Venkatesh and Sigalapalli, Dilep Kumar and Godugu, Chandraiah
Cell death & disease, ISSN 2041-4889, 01/2020, Volume 11, Issue 1, pp. 21 - 21
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Histone deacetylase | Bcl-2 protein | Imiquimod | Hyperplasia | Immunoblotting | AKT protein | Cyclin D1 | Macrophages | Lipopolysaccharides | Proteins | Keratin | Mitochondria | DNA fragmentation | Cell cycle | Skin diseases | Membrane potential | G1 phase | NF-κB protein | Immune response | Psoriasis | Cytokines | Keratinocytes | Inflammation | Nuclear transport | Molecular modelling | Cytoplasm | Apoptosis | Index Medicus
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6. Full Text Repurposing an old drug for new use: Niclosamide in psoriasis‐like skin inflammation
by Thatikonda, Sowjanya and Pooladanda, Venkatesh and Godugu, Chandraiah
Journal of cellular physiology, ISSN 0021-9541, 06/2020, Volume 235, Issue 6, pp. 5270 - 5283
NFATc‐1 | drug repurposing | niclosamide | p65 NF‐κB | psoriasis | STAT3 | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Reactive oxygen species | Transcription factors | Toxicity | Imiquimod | Hyperplasia | Niclosamide | AKT protein | Macrophages | Lipopolysaccharides | Anticancer properties | Mitochondria | DNA fragmentation | Cell cycle | Skin diseases | Biocompatibility | Membrane potential | Toxic diseases | Deoxyribonucleic acid--DNA | G1 phase | Immune response | Psoriasis | Cytokines | Stat3 protein | Keratinocytes | Inflammation | Signaling | Drug discovery | Apoptosis | Index Medicus
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7. Nanoceria suppresses multiple low doses of streptozotocin-induced Type 1 diabetes by inhibition of Nrf2/NF-κB pathway and reduction of apoptosis
by Khurana, Amit and Tekula, Sravani and Godugu, Chandraiah
Nanomedicine (London, England), ISSN 1743-5889, 2018, Volume 13, Issue 15, pp. 1905 - 1922
NF-κB | inflammation | Nrf2 | pancreas | nanoceria | apoptosis | oxidative stress | caspase-3 | SOD1 | Type 1 diabetes mellitus | Science & Technology - Other Topics | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Reactive Oxygen Species - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Cerium - chemistry | Streptozocin | Diabetes Mellitus, Type 1 - metabolism | Male | NF-kappa B - metabolism | Cerium - therapeutic use | Tissue Distribution | Diabetes Mellitus, Type 1 - chemically induced | Inflammation Mediators - metabolism | Hypoglycemic Agents - therapeutic use | Cytokines - metabolism | Signal Transduction | Diabetes Mellitus, Type 1 - pathology | Pancreas - drug effects | Pancreas - pathology | Hypoglycemic Agents - chemistry | Pancreas - metabolism | Diabetes Mellitus, Type 1 - drug therapy | Animals | NF-E2-Related Factor 2 - metabolism | Mice | Oxidative Stress - drug effects
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8. Full Text Niclosamide alleviates pulmonary fibrosis in vitro and in vivo by attenuation of epithelial-to-mesenchymal transition, matrix proteins & Wnt/β-catenin signaling: A drug repurposing study
by Boyapally, Raju and Pulivendala, Gauthami and Bale, Swarna and Godugu, Chandraiah
Life sciences (1973), ISSN 0024-3205, 03/2019, Volume 220, pp. 8 - 20
Niclosamide | Pulmonary fibrosis | EMT | Wnt/β-catenin | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Wnt protein | Mesenchyme | Migration | Lung diseases | Proteins | β-catenin | Signaling | Scars | Bleomycin | Fibrosis | Attenuation | In vivo methods and tests | Drug discovery | Index Medicus
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9. Full Text An adaptogen: Withaferin a ameliorates in vitro and in vivo pulmonary fibrosis by modulating the interplay of fibrotic, matricelluar proteins, and cytokines
by Bale, Swarna and Venkatesh, Pooladanda and Sunkoju, Manoj and Godugu, Chandraiah
Frontiers in pharmacology, ISSN 1663-9812, 03/2018, Volume 9, pp. 248 - 248
Epithelial to mesenchymal transition | Angiogenesis | Withaferin A | Extracellular matrix | Inflammation | Pulmonary fibrosis | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Development and progression | Care and treatment | Health aspects | Lactones | epithelial to mesenchymal transition | inflammation | angiogenesis | extracellular matrix | pulmonary fibrosis
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