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Cancer Research, ISSN 0008-5472, 07/2014, Volume 74, Issue 18, pp. 5057 - 5069
Cancer immunotherapy generally offers limited clinical benefit without coordinated strategies to mitigate the immunosuppressive nature of the tumor... 
ACTIVATION | INHIBITION | MICROENVIRONMENT | ONCOLOGY | ADENOCARCINOMA | INFLAMMATION | KINASE | CSF | POLARIZATION | IPILIMUMAB | PROGRESSION | Receptor, Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Immunotherapy - methods | Receptor, Macrophage Colony-Stimulating Factor - immunology | Adenocarcinoma - pathology | Macrophage Colony-Stimulating Factor - biosynthesis | Mannose-Binding Lectins - biosynthesis | Tissue Array Analysis | Humans | Lectins, C-Type - immunology | Tumor Microenvironment | Deoxycytidine - pharmacology | Lectins, C-Type - biosynthesis | Female | Receptors, Cell Surface - biosynthesis | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Signal Transduction | Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Adenocarcinoma - immunology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - therapy | Random Allocation | Carcinoma, Pancreatic Ductal - pathology | Receptors, Cell Surface - immunology | Macrophage Colony-Stimulating Factor - immunology | Animals | Mannose-Binding Lectins - immunology | Pancreatic Neoplasms - immunology | T-Lymphocytes - immunology | Mice | Deoxycytidine - analogs & derivatives | Cohort Studies | Pancreatic Neoplasms - therapy | Index Medicus | macrophage | chemoresistance | pancreatic cancer | cytokines | innate immunity | immune checkpoint
Journal Article
Cancer Research, ISSN 0008-5472, 02/2013, Volume 73, Issue 3, pp. 1128 - 1141
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 5, pp. 651 - 662
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 5/2014, Volume 63, Issue 5, pp. 513 - 528
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 5640 - 5640
Journal Article
Lab on a Chip, ISSN 1473-0197, 01/2018, Volume 18, Issue 23, pp. 3687 - 3702
Most cancer treatment strategies target cell proliferation, angiogenesis, migration, and intravasation of tumor cells in an attempt to limit tumor growth and... 
Biotechnology | Drug delivery systems | Sensitivity analysis | Feasibility analysis | Metastasis | Cancer therapies | Cell adhesion & migration | Medicine | Angiogenesis | Cell growth | Nutrients | Microfluidics | Tumors | Cancer
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2009, Volume 182, Issue 3, pp. 1746 - 1755
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 02/2018, Volume 36, Issue 4, pp. 704 - 704
Conference Proceeding
The Journal of Immunology, ISSN 0022-1767, 09/2002, Volume 169, Issue 5, pp. 2756 - 2761
Regulatory T cells (T,,g) that prevent autoimmune diseases by suppression of self-reactive T cells may also suppress the immune response against cancer. In... 
IMMUNOTHERAPY | TOLERANCE | CONSEQUENCE | GENERATION | MICE | THYMECTOMY | IMMUNOLOGY | SUPPRESSION | ANTITUMOR IMMUNE-RESPONSE | PROGRESSIVE FIBRO-SARCOMA | IMMUNOLOGICALLY MEDIATED REGRESSION | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Breast Neoplasms - immunology | Coculture Techniques | Humans | Middle Aged | Male | Interferon-gamma - metabolism | T-Lymphocytes, Regulatory - pathology | Lymphocyte Activation - immunology | Adenocarcinoma - metabolism | Carcinoma, Ductal, Breast - pathology | Carcinoma, Ductal, Breast - metabolism | Receptors, Interleukin-2 - biosynthesis | Adenocarcinoma - blood | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Lymph Nodes - metabolism | Lymph Nodes - immunology | CTLA-4 Antigen | Antigens, Differentiation - biosynthesis | T-Lymphocyte Subsets - pathology | Immunoconjugates | Pancreatic Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Antigens, CD | T-Lymphocytes, Regulatory - metabolism | Lymph Nodes - pathology | T-Lymphocyte Subsets - cytology | Carcinoma, Ductal, Breast - immunology | Leukocyte Common Antigens - biosynthesis | Carcinoma, Ductal, Breast - blood | Breast Neoplasms - metabolism | Abatacept | Cell Division - immunology | T-Lymphocytes, Helper-Inducer - immunology | Interferon-gamma - antagonists & inhibitors | T-Lymphocytes, Regulatory - cytology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Pancreatic Neoplasms - blood | Cytokines - metabolism | Cells, Cultured | Immunophenotyping | Lymphocytes, Tumor-Infiltrating - pathology | Breast Neoplasms - pathology | Down-Regulation - immunology | Breast Neoplasms - blood | Lymphocyte Count | Aged | Cytokines - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 12/2016, Volume 76, Issue 24 Supplement, pp. A70 - A70
Journal Article
Molecular Cancer, ISSN 1476-4598, 07/2007, Volume 6, Issue 1, pp. 48 - 48
Background: Resistance to modern adjuvant treatment is in part due to the failure of programmed cell death. Therefore the molecules that execute the apoptotic... 
CANCER-CELLS | BREAST-CANCER | ONCOLOGY | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | PROSTATE-CANCER | TUMOR | PROLIFERATION | DEATH | RECEPTORS | CHEMOTHERAPY | Azabicyclo Compounds - pharmacology | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Tritium | Antineoplastic Agents - therapeutic use | Positron-Emission Tomography | Lung - cytology | Azabicyclo Compounds - metabolism | Antineoplastic Agents - metabolism | Brain - metabolism | Carbamates - metabolism | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Pancreatic Neoplasms - drug therapy | Kidney - metabolism | Adenocarcinoma - metabolism | Azabicyclo Compounds - therapeutic use | Female | Antineoplastic Agents - pharmacology | Lung - metabolism | Radioligand Assay | Receptors, sigma - metabolism | Carbamates - pharmacology | Binding, Competitive | Cell Survival - drug effects | Brain - cytology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Kidney - cytology | Receptors, sigma - agonists | Adenocarcinoma - drug therapy | Animals | Signal Transduction - drug effects | Survival Analysis | Cell Line, Tumor | Ligands | Mice | Neoplasms, Experimental - metabolism | Carbamates - therapeutic use | Neoplasms, Experimental - drug therapy | Care and treatment | Diagnosis | Health aspects | Ligands (Biochemistry) | Pancreatic cancer | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 07/2019, Volume 10, Issue 46, pp. 4761 - 4775
Over 95% of pancreatic adenocarcinomas (PDACs), as well as a large fraction of other tumor types, such as colorectal adenocarcinoma, are driven by KRAS... 
Journal Article
Journal Article