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Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2016, Volume 126, Issue 4, pp. 1323 - 1336
Vascular calcification is a common feature of major cardiovascular diseases. Extracellular vesicles participate in the formation of microcalcifications that... 
MEDICINE, RESEARCH & EXPERIMENTAL | MYOCARDIAL-INFARCTION | NONSPECIFIC ALKALINE-PHOSPHATASE | MINERALIZATION | TRANS-GOLGI NETWORK | CARDIOVASCULAR-DISEASE | ATHEROSCLEROSIS | MATRIX VESICLES | PROTEINS | MASS-SPECTROMETRY | GENOME-WIDE ASSOCIATION | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Casein Kinase I - genetics | Humans | Vascular Calcification - genetics | Adaptor Proteins, Vesicular Transport - genetics | Myocytes, Smooth Muscle - pathology | rab GTP-Binding Proteins - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Vascular Calcification - metabolism | Cell-Derived Microparticles - metabolism | Plaque, Atherosclerotic - pathology | Myocytes, Smooth Muscle - metabolism | Extracellular Matrix Proteins - metabolism | Calcium-Binding Proteins - metabolism | rab GTP-Binding Proteins - metabolism | Alkaline Phosphatase - genetics | Plaque, Atherosclerotic - metabolism | Cell-Derived Microparticles - genetics | Carrier Proteins - biosynthesis | Extracellular Matrix Proteins - genetics | Cells, Cultured | Vascular Calcification - pathology | Mice, Knockout | Protein Transport | Carrier Proteins - genetics | Muscle, Smooth, Vascular - pathology | Animals | Alkaline Phosphatase - biosynthesis | Casein Kinase I - metabolism | Mice | Casein Kinase II - metabolism | Calcium-Binding Proteins - genetics | Cellular proteins | Molecular targeted therapy | Innovations | Development and progression | Genetic aspects | Properties | Coronary heart disease | Proteins | Statistical analysis | Rodents | Calcification | Acute coronary syndromes | Metabolism | Experiments | Manuscripts | Carotid arteries | Veins & arteries
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4731 - 4738
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 07/2017, Volume 121, Issue 3, pp. 220 - 233
Rationale: Mitochondrial changes occur during cell differentiation and cardiovascular disease. DRP1 (dynamin-related protein 1) is a key regulator of... 
atherosclerosis | collagen | myocytes, smooth muscle | mitochondria | oxidative stress | INFANTILE ENCEPHALOPATHY | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROTIC PLAQUES | VASCULAR CALCIFICATION | smooth muscle | OSTEOBLASTIC DIFFERENTIATION | MATRIX VESICLES | SMOOTH-MUSCLE-CELL | MAMMALIAN-CELLS | myocytes | MITOCHONDRIAL FISSION | RETICULUM EXIT SITES | PERIPHERAL VASCULAR DISEASE | ENDOPLASMIC-RETICULUM | HEMATOLOGY | Carotid Artery Diseases - prevention & control | RNA, Small Interfering - genetics | Humans | Oxidative Stress - physiology | Myocytes, Smooth Muscle - pathology | Male | GTP Phosphohydrolases - antagonists & inhibitors | Mice, 129 Strain | Vascular Calcification - metabolism | Carotid Artery Diseases - pathology | Myocytes, Smooth Muscle - drug effects | Carotid Artery Diseases - metabolism | Myocytes, Smooth Muscle - metabolism | Mice, Inbred C57BL | Mitochondrial Proteins - antagonists & inhibitors | Cells, Cultured | Vascular Calcification - prevention & control | Mice, Transgenic | Mitochondrial Proteins - biosynthesis | Microtubule-Associated Proteins - antagonists & inhibitors | Collagen - secretion | Microtubule-Associated Proteins - biosynthesis | Vascular Calcification - pathology | Animals | Mice | Oxidative Stress - drug effects | RNA, Small Interfering - administration & dosage | GTP Phosphohydrolases - biosynthesis | Calcification (ectopic) | Immunohistochemistry | Oxidative stress | Alkaline phosphatase | Femur | Calcium | Smooth muscle | Osteoblasts | Proteins | Mitochondria | Clonal deletion | Mineralization | Aorta | Bone density | Carotid artery | Bone loss | Secretion | RNA-mediated interference | Exploration | Subtilisin | Kexin | Arteriosclerosis | Collagen | Dynamin | Calcification | Cytoskeleton | Cardiovascular diseases | aortic valve calcification | Mechanisms | Oxidant Stress | Vascular Biology | dynamin-related protein 1 | calcification | DNM1L | Basic Science Research
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 13, pp. 2306 - 2306
  <71 ng/mL, median) was associated with a higher risk of MACCE (Figure B; HR=2.79, 95% CI: 1.62-4.8, p<0.001). [...]high sortilin levels were associated with... 
Cardiovascular | Internal Medicine | Cardiovascular diseases | Aged | Risk factors | Calcification | Diabetes | Health risk assessment | Mortality
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2012, Volume 27, Issue 3, pp. 575 - 585
Journal Article