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Neuron, ISSN 0896-6273, 01/2015, Volume 85, Issue 2, pp. 275 - 288
Neuronal development requires a complex choreography of transcriptional decisions to obtain specific cellular identities. Realizing the ultimate goal of... 
Journal Article
eLife, ISSN 2050-084X, 09/2018, Volume 7
Vascular endothelial cell (EC) function depends on appropriate organ-specific molecular and cellular specializations. To explore genomic mechanisms that... 
blood-brain barrier | mouse | single cell RNA-seq | neuroscience | chromosomes | DNA methylation | Wnt | gene expression | accessible chromatin | vascular endothelial cell | ENDOGENOUS RETROVIRUSES | DNA METHYLATION | PROTEIN-COUPLED RECEPTOR | IN-VIVO | BIOLOGY | GENE-EXPRESSION | INTEGRATIVE GENOMICS VIEWER | BLOOD-BRAIN-BARRIER | PHENOTYPIC HETEROGENEITY | DIFFERENTIAL EXPRESSION ANALYSIS | TISSUE MICROENVIRONMENT | Chromatin - metabolism | Multigene Family | Epigenesis, Genetic | Male | RNA, Messenger - metabolism | Brain - metabolism | Base Sequence | Transcription, Genetic | Lung - metabolism | Single-Cell Analysis | Wnt Signaling Pathway | Green Fluorescent Proteins - metabolism | Endothelial Cells - metabolism | Liver - metabolism | RNA, Messenger - genetics | Mice, Transgenic | DNA Methylation - genetics | Organ Specificity | Amino Acid Motifs | Dopa Decarboxylase - metabolism | Transcription Factors - metabolism | Animals | Sequence Analysis, RNA | Central Nervous System - cytology | Endothelial Cells - cytology | Chromatin | RNA | Analysis | Genes | Liver | Genetic research | Genetic aspects | Genetic transcription | Endothelium | Kidneys | Wnt protein | Genomics | Central nervous system | Principal components analysis | Genomes | Regulatory sequences | Gene expression | Ribonucleic acid--RNA | Arteries | Endothelial cells | Medicine | Specialization | Blood-brain barrier | Deoxyribonucleic acid--DNA
Journal Article
Genome Research, ISSN 1088-9051, 10/2015, Volume 25, Issue 10, pp. 1456 - 1465
Journal Article
Trends in Genetics, ISSN 0168-9525, 10/2018, Volume 34, Issue 10, pp. 790 - 805
Omics data contain signals from the molecular, physical, and kinetic inter- and intracellular interactions that control biological systems. Matrix... 
matrix factorization | deconvolution | genomics | single cell | dimension reduction | unsupervised learning | GENE-EXPRESSION DATA | SINGULAR-VALUE DECOMPOSITION | SET ENRICHMENT ANALYSIS | SIGNATURES | GENETICS & HEREDITY | POPULATION-STRUCTURE | NONNEGATIVE MATRIX | INFERENCE | IDENTIFICATION | MICROARRAY DATA | INDEPENDENT COMPONENT ANALYSIS
Journal Article
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, ISSN 1552-4841, 09/2019
Recent genome-wide association studies (GWAS) identified numerous schizophrenia (SZ) and Alzheimer's disease (AD) associated loci, most outside protein-coding... 
Journal Article
International Journal of Developmental Neuroscience : Official Journal of the International Society for Developmental Neuroscience, ISSN 0736-5748, 12/2016, Volume 55, p. 109
The development of the central nervous system (CNS) is a complex orchestration of stem cells, transcription factors, growth/differentiation factors, and... 
Studies | Transcription factors | Coding | Central nervous system | Stem cells | Nervous system | Ribonucleic acid--RNA | Differentiation
Journal Article
Cancer research, ISSN 0008-5472, 07/2019, Volume 79, Issue 19, pp. 5102 - 5112
Tumor heterogeneity provides a complex challenge to cancer treatment and is a critical component of therapeutic response, disease recurrence, and patient... 
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S1260 - S1261
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2019, Volume 116, Issue 18, pp. 9103 - 9114
Journal Article