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aged; aged, 80 and over; alzheimer disease/blood; alzheimer disease/immunology; amyloid beta-peptides/immunology; amyloid beta-peptides/metabolism; amyloid beta-protein precursor/genetics; animals; animals, newborn; cells, cultured; cerebral cortex/cytology; disease models, animal; dose-response relationship, drug; dose-response relationship, immunologic; double-blind method; enzyme-linked immunosorbent assay; female; gene expression regulation/drug effects; gene expression regulation/genetics; green fluorescent proteins/genetics; hippocampus/cytology; humans; immunoglobulin g/metabolism; immunoglobulin g/pharmacology; male; mice; mice, transgenic; microglia/drug effects; microglia/metabolism; microscopy, confocal; middle aged; mutation/genetics; neurons/drug effects; neurons/metabolism; neuroprotective agents/metabolism; neuroprotective agents/pharmacology; peptide fragments/metabolism; plaque, amyloid/immunology; plaque, amyloid/metabolism; presenilin-1/genetics; protein binding/drug effects; rats; rats, sprague-dawley; receptors, chemokine/genetics; statistics, nonparametric; time factors; tumor necrosis factor-alpha/metabolism; p38 mitogen-activated protein kinases/metabolism (1) 1
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Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e68755 - e68755
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 18, pp. 5679 - 5684
Journal Article
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-79 - S-80
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2019, Volume 116, Issue 33, pp. 16420 - 16429
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2012, Volume 32, Issue 28, pp. 9677 - 9689
Passive immunization against beta-amyloid (A beta) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD).... 
APP TRANSGENIC MICE | NATURAL OLIGOMERS | HUMAN IGG1 | ALZHEIMERS-DISEASE | PROTEIN-KINASE | LONG-TERM POTENTIATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | PASSIVE-IMMUNIZATION | SECRETED OLIGOMERS | P38 MAP KINASE | Microglia - metabolism | Humans | Middle Aged | Male | Green Fluorescent Proteins - genetics | Neuroprotective Agents - metabolism | Alzheimer Disease - pathology | Neuroprotective Agents - pharmacology | Time Factors | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Statistics, Nonparametric | Aged, 80 and over | Neurons - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Alzheimer Disease - immunology | Receptors, Chemokine - genetics | Plaque, Amyloid - immunology | Disease Models, Animal | Animals, Newborn | Rats | Mice, Transgenic | Mutation - genetics | Rats, Sprague-Dawley | Microscopy, Confocal | Plaque, Amyloid - metabolism | Mice | CX3C Chemokine Receptor 1 | Alzheimer Disease - blood | Immunoglobulin G - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dose-Response Relationship, Immunologic | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Immunoglobulin G - pharmacology | Female | Neurons - drug effects | Peptide Fragments - metabolism | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Plaque, Amyloid - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Alzheimer Disease - therapy | Cells, Cultured | Presenilin-1 - genetics | Hippocampus - cytology | Gene Expression Regulation - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Amyloid beta-Peptides - immunology | Aged | Index Medicus
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2017, Volume 9, Issue 403, p. eaag0394
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2007, Volume 110, Issue 12, pp. 4037 - 4046
Recombinant human rhApo2L/TRAIL selectively stimulates apoptosis in various cancer cells through its receptors DR4 and DR5, and is currently in clinical... 
DEATH RECEPTORS | APOPTOSIS-INDUCING LIGAND | ANTI-CD20 MONOCLONAL-ANTIBODY | DECOY RECEPTORS | B-CELL LYMPHOMAS | IN-VIVO | HISTOLOGIC SUBTYPES | FOLLICULAR LYMPHOMA | CYTOCHROME-C RELEASE | HEMATOLOGY | CASPASE ACTIVATION | Recombinant Proteins - therapeutic use | Receptors, TNF-Related Apoptosis-Inducing Ligand - antagonists & inhibitors | Apoptosis - drug effects | Humans | Antibodies, Monoclonal - therapeutic use | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Lymphocyte Depletion | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Complement System Proteins - metabolism | Antineoplastic Agents - agonists | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | TNF-Related Apoptosis-Inducing Ligand - agonists | Female | Antineoplastic Agents - pharmacology | Lymphoma, Non-Hodgkin - drug therapy | Receptors, Tumor Necrosis Factor - metabolism | Antibodies, Monoclonal, Murine-Derived | Antibodies, Monoclonal - pharmacology | Rituximab | Recombinant Proteins - agonists | Recombinant Proteins - pharmacology | Mice, SCID | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Mice, Inbred ICR | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Antibody Formation - drug effects | Lymphoma, Non-Hodgkin - metabolism | Cell Line, Tumor | Mice | Killer Cells, Natural - metabolism | Drug Resistance, Neoplasm - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 08/2019, Volume 28, Issue 8, pp. 2111 - 2123.e6
Complement pathway overactivation can lead to neuronal damage in various neurological diseases. Although Alzheimer’s disease (AD) is characterized by β-amyloid... 
tauopathy | amyloidosis | Alzheimer’s disease | neuroinflammation | neurodegeneration | synapse | complement | astrocyte | microglia | BETA OLIGOMERS | PROTEIN | VARIANTS | ENDOGENOUS TAU | MICROGLIA | ALZHEIMERS-DISEASE | SYNAPSE LOSS | DEFICITS | EXPRESSION | TRANSGENIC MICE | CELL BIOLOGY
Journal Article