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Journal of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 2017, Issue 1_suppl, pp. 13 - 13
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 35, Issue 6_suppl, pp. 13 - 13
Journal Article
Australasian Psychiatry, ISSN 1039-8562, 8/2018, Volume 26, Issue 4, pp. 366 - 375
Objectives: Huntington’s disease (HD) is a profoundly incapacitating, and ultimately fatal, neurodegenerative disease. HD is presently incurable, so the... 
neuropsychiatry | neuropsychiatric manifestations | Huntington’s disease | psychiatry
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2018
Preclinically, AKT kinase inhibition restores drug sensitivity in platinum-resistant tumors. Here the pan-AKT kinase inhibitor afuresertib was given in... 
Journal Article
by Coleman, Robert L and Coleman, R L and Oza, Amit M and Oza, A M and Lorusso, D and Lorusso, Domenica and Aghajanian, C and Aghajanian, Carol and Oaknin, A and Oaknin, Ana and Dean, A and Dean, Andrew and Colombo, N and Colombo, Nicoletta and Weberpals, Johanne I and Weberpals, J I and Clamp, Andrew and Clamp, A and Scambia, Giovanni and Scambia, G and Leary, A and Leary, Alexandra and Holloway, Robert W and Holloway, R W and Gancedo, M Amenedo and Gancedo, Margarita Amenedo and Fong, Peter C and Fong, P C and Goh, Jeffrey C and Goh, J C and O'Malley, David M and O'Malley, D M and Armstrong, Deborah K and Armstrong, D K and Garcia-Donas, Jesus and Garcia-Donas, J and Swisher, E M and Swisher, Elizabeth M and Floquet, A and Floquet, Anne and Konecny, Gottfried E and Konecny, G E and McNeish, I A and McNeish, Iain A and Scott, C L and Scott, Clare L and Cameron, Terri and Maloney, Lara and Isaacson, Jeff and Goble, Sandra and Grace, Caroline and Harding, Thomas C and Raponi, Mitch and Sun, James and Lin, Kevin K and Giordano, Heidi and Ledermann, J A and Ledermann, Jonathan A and Buck, M and Friedlander, M L and Harnett, P and Kichenadasse, G and Denys, H and Dirix, L and Vergote, I and Elit, L and Ghatage, P and Plante, M and Provencher, D and Welch, S and Gladieff, L and Joly, F and Lortholary, A and Lotz, J and Medioni, J and Tredan, O and You, B and El-Balat, A and Hänle, C and Krabisch, P and Neunhöffer, T and Pölcher, M and Wimberger, P and Amit, A and Kovel, S and Leviov, M and Safra, T and Shapira-Frommer, R and Stemmer, S and Bologna, A and Pignata, S and Sabbatini, R F and Tamberi, S and Zamagni, C and O'Donnell, A and Herraez, A Casado and Guerra, E M and Palacio, I and Romero, I and Sanchez, A and ... and ARIEL3 Investigators and ARIEL3 investigators
The Lancet, ISSN 0140-6736, 10/2017, Volume 390, Issue 10106, pp. 1949 - 1961
Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a mutation or high percentage of... 
MEDICINE, GENERAL & INTERNAL | MULTICENTER | SOLID TUMORS | BEVACIZUMAB | OPEN-LABEL | CANCER | HETEROZYGOSITY | EPITHELIAL OVARIAN | CHEMOTHERAPY | Double-Blind Method | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Treatment Outcome | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Indoles - administration & dosage | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Maintenance Chemotherapy - methods | Internationality | Ovarian Neoplasms - therapy | Female | Aged | Molecular Targeted Therapy - methods | Clinical trials | Care and treatment | Carcinoma | Drug therapy | Ovarian cancer | Cancer | Analysis | Chemotherapy | Ovarian carcinoma | Platinum | Biomarkers | Mutation | Cancer therapies | Tumors | Homologous recombination | Central nervous system | Poly(ADP-ribose) | Homology | Genomes | Fallopian tube | ADP | Anticancer properties | Metastases | Homologous recombination repair | Randomization | Pain | Motivation | Ribose | Hemoglobin | Alanine | Anemia | Poly(ADP-ribose) polymerase | Breast cancer | Patients | Survival | Heterozygosity | Abdomen | Polymerase | Inhibitors | Point mutation | Loss of heterozygosity | Antitumor activity | Aspartate aminotransferase | Peritoneum
Journal Article
by Ikram, Arfan and Fornage, Myriam and Smith, G.D and Seshai, Sudha and Schmidt, Reinhold and Debette, Stéphanie and Vrooman, Henri and Sigurdsson, Stefan and Ropele, Stefan and Taal, Rob and Mook-Kanamori, Dennis and Coker, Laura and Longstreth, W.T and Niessen, Wiro and DeStefano, Anita and Beiser, Alexa and Zijdenbos, A.P and Struchalin, Maksim and Jack Jr., Clifford and Rivadeneira Ramirez, Fernando and Uitterlinden, Ané and Knopman, David and Hartikainen, A.L and Pennell, Craig and Thiering, Eelisabeth and Steegers, Eric and Hakonarson, Hakon and Heinrich, Joachim and Palmer, Cameron and Jarvelin, Marjo-Riitta and McCarthy, Mark and Grant, Struan and Pourcain, Beate and Timpson, Nicholas and Sovio, Ulla and Nalls, Michael and Au, Rhoda and Hofman, Albert and Gudnason, Haukur and Lugt, Aad and Harris, Tamara and Meeks, William and Vernooij, Meike and Buchem, Mark and Catellier, Diane and Jaddoe, Vincent and Gudnason, Vilmundur and Windham, B Gwen and Wolf, Philip and Duijn, Cornelia and Mosley, Thomas and Launer, Lenore and Breteler, Monique and DeCarli, Charles and Adair, Linda and Ang, Wei and Atalay, Mustafa and Beijsterveldt, Toos and Bergen, Nienke and Benke, Paul and Berry, Diane and Coin, Lachlan and Davis, Oliver S and Elliott, Paul and Flexeder, Claudia and Frayling, Timothy and Gaillard, Romy and Groen-Blokhuis, Maria and Goh, L.-K and Haworth, Claire M and Hadley, David and Hedebrand, Johannes and Hinney, Anke and Hirschhorn, Joel and Holloway, John and Holst, J.J and Hottenga, Jouke Jan and Horikoshi, Momoko and Huikari, Ville and Hypponen, Elina and Kilpeläinen, Tuomas and Kirin, Mirna and Kowgier, Matthew and Lakka, Timo and Lange, Leslie and Lawlor, Debbie and Lehtimäki, Terho and Lewin, Alex and Lindgren, Cecilia and Lindi, Virpi and Maggi, Reedik and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Murray, Jeffrey and Nivard, Michel and Nohr, Christian and Ntalla, Ioanna and Oken, Emily and Panoutsopoulou, Kalliope and ... and Cohorts Heart Aging Res Genomic Ep and Early Growth Genetics EGG Consorti and Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium and Early Growth Genetics Consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and Early Growth Genetics (EGG) Consortium and Mittuniversitetet and Institutionen för samhällsvetenskap and Fakulteten för humanvetenskap
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 539 - 544
Journal Article
by Hinney, A and Kesselmeier, M and Jall, S and Volckmar, A.-L and Föcker, M and Antel, J and Heid, I. M and Winkler, T. W and Grant, S. F. A and Guo, Y and Bergen, A. W and Kaye, W and Berrettini, W and Hakonarson, H and Herpertz-Dahlmann, B and de Zwaan, M and Herzog, W and Ehrlich, S and Zipfel, S and Egberts, K. M and Adan, R and Brandys, M and van Elburg, A and Boraska Perica, V and Franklin, C. S and Tschöp, M. H and Zeggini, E and Bulik, C. M and Collier, D and Scherag, A and Müller, T. D and Hebebrand, J and Perica, Vesna Boraska and Franklin, Christopher S and Floyd, James A. B and Thornton, Laura M and Huckins, Laura M and Southam, Lorraine and Rayner, N. William and Tachmazidou, Ioanna and Klump, Kelly L and Treasure, Janet and Lewis, Cathryn M and Schmidt, Ulrike and Tozzi, Federica and Iezebrink, Kirsty and Hebebrand, Johannes and Gorwood, Philip and Adan, Roger A. H and Kas, Martien J. H and Favaro, Angela and Santonastaso, Paolo and Fernández-Aranda, Fernando and Gratacos, Monica and Rybakowski, Filip and Dmitrzak-Weglarz, Monika and Kaprio, Jaakko and Keski-Rahkonen, Anna and Raevuori-Helkamaa, Anu and van Furth, Eric F and Slof-Op't Landt, Margarita C. T and Hudson, James I and Reichborn-Kjennerud, Ted and Knudsen, Gun Peggy S and Monteleone, Palmiero and Kaplan, Allan S and Karwautz, Aneas and Hakonarson, Hakon and Berrettini, Wade H and Guo, Yiran and Li, Dong and Schork, Nicholas J and Komaki, Gen and Ando, Tetsuya and Inoko, Hidetoshi and Esko, Tõnu and Fischer, Krista and Männik, Katrin and Metspalu, Anes and Baker, Jessica H and Cone, Roger D and Dackor, Jennifer and DeSocio, Janiece E and Hilliard, Christopher E and O'Toole, Julie K and Pantel, Jacques and Szatkiewicz, Jin P and Taico, Chrysecolla and Zerwas, Stephanie and Trace, Sara E and Davis, Oliver S. P and Helder, Sietske and Bühren, Katharina and Burghardt, Roland and de Zwaan, Martina and Egberts, Karin and Ehrlich, Stefan and Herpertz-Dahlmann, Beate and Herzog, Wolfgang and Imgart, Hartmut and ... and WTCCC3 and GCAN and Children's Hosp Philadelphia and EGG and GIANT and Price Fdn Collaborative Grp and Children’s Hospital of Philadelphia/Price Foundation and Price Foundation Collaborative Group
Molecular psychiatry, ISSN 1359-4184, 2017, Volume 22, Issue 2, pp. 192 - 201
Journal Article