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science & technology (25) 25
life sciences & biomedicine (23) 23
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humans (11) 11
abstracts (9) 9
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brain tumors (8) 8
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high performance liquid chromatography (2) 2
infratentorial neoplasms - genetics (2) 2
lipidomics (2) 2
medicine & public health (2) 2
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single-cell analysis - methods (2) 2
solid tumors (2) 2
tert promoter (2) 2
transcription factors (2) 2
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[sdv.can]life sciences [q-bio]/cancer (1) 1
[sdv.neu.nb]life sciences [q-bio]/neurons and cognition [q-bio.nc]/neurobiology (1) 1
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administration, intravenous (1) 1
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age distribution (1) 1
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amino acid sequence (1) 1
angiogenesis inhibitors - administration & dosage (1) 1
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1. Full Text p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction
by Dinhof, Carina and Pirker, Christine and Kroiss, Philipp and Kirchhofer, Dominik and Gabler, Lisa and Gojo, Johannes and Loetsch-Gojo, Daniela and Stojanovic, Mirjana and Timelthaler, Gerald and Ferk, Franziska and Knasmueller, Siegfried and Reisecker, Johannes and Spiegl-Kreinecker, Sabine and Birner, Peter and Preusser, Matthias and Berger, Walter
Cancers, ISSN 2072-6694, 11/2020, Volume 12, Issue 11, p. 1
Life Sciences & Biomedicine | Oncology | Science & Technology | Physiological aspects | Transcription factors | Tumor proteins | Cell death | Health aspects | YK-4-279 | ETS factor inhibitor | parthanatos | ETS1 | p53 | PARylation
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2. Full Text Liquid biomarkers for pediatric brain tumors: Biological features, advantages and perspectives
by Madlener, Sibylle and Gojo, Johannes
Journal of personalized medicine, ISSN 2075-4426, 11/2020, Volume 10, Issue 4, pp. 1 - 15
Brain tumor | Pediatric cancer | DdPCR | Biosensor | MiRNA | Liquid biopsy | Cerebrospinal fluid | Next-generation sequencing (NGS) | Neuroimaging | Pediatrics | Decision making | Invasiveness | Brain tumors | Brain cancer | Mortality | Central nervous system | Nervous system | Gene expression | Cancer therapies | Patients | Body fluids | Precision medicine | Blood-brain barrier | Magnetic resonance imaging | Biopsy | MicroRNAs | Biomarkers | Mutation | Solid tumors | Deoxyribonucleic acid--DNA | Tumors | ddPCR | brain tumor | biosensor | liquid biopsy | cerebrospinal fluid | pediatric cancer
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3. Full Text Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
by Filbin, Mariella G and Tirosh, Itay and Hovestadt, Volker and Shaw, McKenzie L and Escalante, Leah E and Mathewson, Nathan D and Neftel, Cyril and Frank, Nelli and Pelton, Kristine and Hebert, Christine M and Haberler, Christine and Yizhak, Keren and Gojo, Johannes and Egervari, Kristof and Mount, Christopher and Van Galen, Peter and Bonal, Dennis M and Nguyen, Quang-De and Beck, Alexander and Sinai, Claire and Czech, Thomas and Dorfer, Christian and Goumnerova, Liliana and Lavarino, Cinzia and Carcaboso, Angel M and Mora, Jaume and Mylvaganam, Ravindra and Luo, Christina C and Peyrl, Andreas and Popović, Mara and Azizi, Amedeo and Batchelor, Tracy T and Frosch, Matthew P and Martinez-Lage, Maria and Kieran, Mark W and Bandopadhayay, Pratiti and Beroukhim, Rameen and Fritsch, Gerhard and Getz, Gad and Rozenblatt-Rosen, Orit and Wucherpfennig, Kai W and Louis, David N and Monje, Michelle and Slavc, Irene and Ligon, Keith L and Golub, Todd R and Regev, Aviv and Bernstein, Bradley E and Suvà, Mario L
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2018, Volume 360, Issue 6386, pp. 331 - 335
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oligodendroglia - metabolism | Cell Proliferation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Humans | Brain Neoplasms - pathology | Carcinogenesis - genetics | Brain Neoplasms - genetics | Mitogen-Activated Protein Kinase 7 - genetics | Glioma - genetics | Oligodendroglia - pathology | Sequence Analysis, RNA - methods | Receptor, Platelet-Derived Growth Factor alpha - genetics | Single-Cell Analysis - methods | Glioma - pathology | Histones - metabolism | Mutation | Oncogenes | RNA sequencing | Histones | Genetic aspects | Gliomas | Health aspects | Methods | Cell proliferation | Therapeutic applications | Brain tumors | Central nervous system | Methionine | Ribonucleic acid--RNA | Glial stem cells | Gene sequencing | Signaling | Hierarchies | Model matching | Precursors | Glioma cells | Stem cells | Genetics | Tumorigenesis | Children | Histone H3 | Tumors | Index Medicus
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4. Full Text Predisposition of Wingless Subgroup Medulloblastoma for Primary Tumor Hemorrhage
by Dominik Reisinger and Johannes Gojo and Gregor Kasprian and Christine Haberler and Andreas Peyrl and Amedeo A Azizi and Lisa Mayr and Monika Chocholous and Marcel Kool and Thomas Czech and Irene Slavc
Neurosurgery, ISSN 0148-396X, 12/2020, Volume 87, p. S37
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5. Full Text Resolving medulloblastoma cellular architecture by single-cell genomics
by Hovestadt, Volker and Smith, Kyle S and Bihannic, Laure and Filbin, Mariella G and Shaw, McKenzie L and Baumgartner, Alicia and DeWitt, John C and Groves, Andrew and Mayr, Lisa and Weisman, Hannah R and Richman, Alyssa R and Shore, Marni E and Goumnerova, Liliana and Rosencrance, Celeste and Carter, Robert A and Phoenix, Timothy N and Hadley, Jennifer L and Tong, Yiai and Houston, Jim and Ashmun, Richard A and DeCuypere, Michael and Sharma, Tanvi and Flasch, Diane and Silkov, Antonina and Ligon, Keith L and Pomeroy, Scott L and Rivera, Miguel N and Rozenblatt-Rosen, Orit and Rusert, Jessica M and Wechsler-Reya, Robert J and Li, Xiao-Nan and Peyrl, Andreas and Gojo, Johannes and Kirchhofer, Dominik and Loetsch, Daniela and Czech, Thomas and Dorfer, Christian and Haberler, Christine and Geyeregger, Rene and Halfmann, Angela and Gawad, Charles and Easton, John and Pfister, Stefan M and Regev, Aviv and Gajjar, Amar and Orr, Brent A and Slavc, Irene and Robinson, Giles W and Bernstein, Bradley E and Suva, Mario L and Northcott, Paul A
Nature (London), ISSN 0028-0836, 08/2019, Volume 572, Issue 7767, pp. 74 - 79
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurons - pathology | Cerebellum - metabolism | Genomics | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Child, Preschool | Infant | Cerebellum - pathology | DNA Copy Number Variations | Cell Lineage | Animals | Medulloblastoma - pathology | Adolescent | Adult | Glutamic Acid - metabolism | Mice | Neurons - metabolism | Medulloblastoma - genetics | Single-Cell Analysis | Child | Medulloblastoma - classification | Usage | Phenotype | Medulloblastoma | Development and progression | Genetic aspects | Structure | Tissues | Observations | Identification and classification | Cerebellum | Populations | Wnt protein | Granule cells | Nervous system | Genomes | Biology | Cell differentiation | Gene expression | Biodiversity | Patients | Subgroups | Heterogeneity | Hedgehog protein | DNA methylation | Mutation | Glutamatergic transmission | Children | Bioinformatics | Deoxyribonucleic acid--DNA | Cancer | Tumors | Index Medicus
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6. Full Text Predisposition of Wingless Subgroup Medulloblastoma for Primary Tumor Hemorrhage
by Reisinger, Dominik and Gojo, Johannes and Kasprian, Gregor and Haberler, Christine and Peyrl, Andreas and Azizi, Amedeo A and Mayr, Lisa and Chocholous, Monika and Kool, Marcel and Czech, Thomas and Slavc, Irene
Neurosurgery, ISSN 0148-396X, 04/2020, Volume 86, Issue 4, pp. 478 - 484
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Surgery | Science & Technology | Tumors in children | Diagnosis | Pediatric research | Hemorrhage | Medulloblastoma | Pediatrics | Neurosurgery | Index Medicus
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7. Full Text Cerebrospinal fluid disturbances after transcallosal surgery: incidence and predictive factors
by Dorfer, Christian and Hosmann, Arthur and Vendl, Julia and Steiner, Irene and Slavc, Irene and Gojo, Johannes and Kasprian, Gregor and Czech, Thomas
Journal of neurosurgery, ISSN 0022-3085, 10/2020, Volume 133, Issue 4, pp. 979 - 987
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Surgery | Science & Technology | Index Medicus | Abridged Index Medicus
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8. Full Text Evaluation and optimization of common lipid extraction methods in cerebrospinal fluid samples
by Reichl, Bernd and Eichelberg, Nicole and Freytag, Matilda and Gojo, Johannes and Peyrl, Andreas and Buchberger, Wolfgang
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, ISSN 1570-0232, 09/2020, Volume 1153, pp. 122271 - 122271
Lipid extraction | Lipidomics | Cerebrospinal fluid | Mass spectrometry | Design of experiments | High performance liquid chromatography | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Index Medicus
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9. Full Text Safety of Ommaya reservoirs in children with brain tumors: a 20-year experience with 5472 intraventricular drug administrations in 98 patients
by Peyrl, Andreas and Chocholous, Monika and Azizi, Amedeo A and Czech, Thomas and Dorfer, Christian and Mitteregger, Dieter and Gojo, Johannes and Minichmayr, Elke and Slavc, Irene
Journal of neuro-oncology, ISSN 0167-594X, 10/2014, Volume 120, Issue 1, pp. 139 - 145
Neurology | Medicine & Public Health | Complications | Ommaya reservoirs | Brain tumors | Oncology | Infections | Children | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Prognosis | Follow-Up Studies | Instillation, Drug | Humans | Brain Neoplasms - pathology | Injections, Intraventricular | Child, Preschool | Infant | Male | Survival Rate | Brain Neoplasms - drug therapy | Drug Delivery Systems | Young Adult | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cerebral Ventricles | Adolescent | Adult | Female | Retrospective Studies | Brain Neoplasms - mortality | Safety | Neoplasm Staging | Child | Catheters, Indwelling | Medical colleges | Complications and side effects | Chemotherapy | Safety and security measures | Cancer | Index Medicus
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10. Full Text Lipid droplet‐mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib
by Englinger, Bernhard and Laemmerer, Anna and Moser, Patrick and Kallus, Sebastian and Röhrl, Clemens and Pirker, Christine and Baier, Dina and Mohr, Thomas and Niederstaetter, Laura and Meier‐Menches, Samuel M and Gerner, Christopher and Gabler, Lisa and Gojo, Johannes and Timelthaler, Gerald and Senkiv, Julia and Jäger, Walter and Kowol, Christian R and Heffeter, Petra and Berger, Walter
International journal of cancer, ISSN 0020-7136, 09/2020, Volume 147, Issue 6, pp. 1680 - 1693
drug sequestration | cancer | Ponatinib | lipid droplets | resistance | Life Sciences & Biomedicine | Oncology | Science & Technology | Tyrosine | Lipophilic | Molecular modelling | Cell survival | Lung cancer | Lipids | Intracellular | Adipocytes | Pharmacokinetics | Fibroblast growth factor receptor 1 | Protein-tyrosine kinase | Index Medicus
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11. Full Text Pharmacokinetics of Bevacizumab in Three Patients Under the Age of 3 Years with CNS Malignancies
by Gojo, Johannes and Sauermann, Robert and Knaack, Ursula and Slavc, Irene and Peyrl, Andreas
Drugs in R&D, ISSN 1174-5886, 9/2017, Volume 17, Issue 3, pp. 469 - 474
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Prospective Studies | Age Factors | Bevacizumab - administration & dosage | Bevacizumab - adverse effects | Humans | Bevacizumab - pharmacokinetics | Child, Preschool | Infant | Angiogenesis Inhibitors - pharmacokinetics | Administration, Intravenous | Angiogenesis Inhibitors - administration & dosage | Female | Angiogenesis Inhibitors - adverse effects | Central Nervous System Neoplasms - drug therapy | Central nervous system diseases | Care and treatment | Pharmacokinetics | Health aspects | Body weight | Analysis | Pediatrics | Patients | Age | Index Medicus | Short Communication
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12. Full Text An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
by Neftel, Cyril and Laffy, Julie and Filbin, Mariella G and Hara, Toshiro and Shore, Marni E and Rahme, Gilbert J and Richman, Alyssa R and Silverbush, Dana and Shaw, McKenzie L and Hebert, Christine M and Dewitt, John and Gritsch, Simon and Perez, Elizabeth M and Gonzalez Castro, L. Nicolas and Lan, Xiaoyang and Druck, Nicholas and Rodman, Christopher and Dionne, Danielle and Kaplan, Alexander and Bertalan, Mia S and Small, Julia and Pelton, Kristine and Becker, Sarah and Bonal, Dennis and Nguyen, Quang-De and Servis, Rachel L and Fung, Jeremy M and Mylvaganam, Ravindra and Mayr, Lisa and Gojo, Johannes and Haberler, Christine and Geyeregger, Rene and Czech, Thomas and Slavc, Irene and Nahed, Brian V and Curry, William T and Carter, Bob S and Wakimoto, Hiroaki and Brastianos, Priscilla K and Batchelor, Tracy T and Stemmer-Rachamimov, Anat and Martinez-Lage, Maria and Frosch, Matthew P and Stamenkovic, Ivan and Riggi, Nicolo and Rheinbay, Esther and Monje, Michelle and Rozenblatt-Rosen, Orit and Cahill, Daniel P and Patel, Anoop P and Hunter, Tony and Verma, Inder M and Ligon, Keith L and Louis, David N and Regev, Aviv and Bernstein, Bradley E and Tirosh, Itay and Suvà, Mario L
Cell (Cambridge), ISSN 0092-8674, 08/2019, Volume 178, Issue 4, pp. 835 - 849.e21
single-cell RNA-sequencing | PDGFRA | glioblastoma subtypes | CDK4 | glioblastoma stem cells | glioblastoma IDH-wildtype | NF1 | lineage tracing | EGFR | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Middle Aged | Brain Neoplasms - pathology | Infant | Male | Heterografts | Tumor Microenvironment - genetics | Glioblastoma - genetics | Single-Cell Analysis - methods | Female | Child | Cell Lineage - genetics | Disease Models, Animal | Mice, Inbred C57BL | Brain Neoplasms - genetics | Genetic Heterogeneity | Cell Plasticity - genetics | Animals | RNA-Seq | Glioblastoma - pathology | Adolescent | Cell Line, Tumor | Mice, Inbred NOD | Aged | Mice | Mutation | Cohort Studies | Glioblastoma multiforme | Analysis | Index Medicus | Glioblastoma IDH-wildtype
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