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Journal of Cell Communication and Signaling, ISSN 1873-9601, 06/2017, Volume 11, Issue 2, pp. 205 - 211
A variety of conditional knock-out mice relying on Tamoxifen-driven ERT2/Cre -mediated recombination are available and have been used to study involvement of... 
Gender | Tamoxifen | ERα | UUO | Fibrosis | ASSAY | CELL BIOLOGY | BREAST-CANCER | SIGNALING PATHWAY | ESTROGEN-RECEPTOR-ALPHA | GROWTH | SEX-DIFFERENCES | KIDNEY | EXPRESSION | ER alpha | Animal experimentation | Metabolites | Analysis | Pharmacy | Drugstores | Kidney diseases | Nuts and Bolts
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 10/2008, Volume 25, Issue 10, pp. 2416 - 2426
Renal fibrosis is the major determinant in progression of kidney disease and results from an inappropriate response to acute and chronic kidney injury.... 
Biomedical Engineering | Biochemistry, general | connective tissue growth factor | Biomedicine | bone morphogenetic protein-7 | transforming growth factor-β | Pharmacy | Medical Law | Pharmacology/Toxicology | renal fibrosis | diabetic nephropathy | Connective tissue growth factor | Diabetic nephropathy | Bone morphogenetic protein-7 | Renal fibrosis | Transforming growth factor-β | EXTRACELLULAR-MATRIX ACCUMULATION | FACTOR-BETA | TGF-BETA | CHEMISTRY, MULTIDISCIPLINARY | transforming growth factor-beta | EPITHELIAL-MESENCHYMAL TRANSITION | EXPERIMENTAL DIABETIC-NEPHROPATHY | HEPATIC STELLATE CELLS | I RECEPTOR KINASE | TRANSFORMING GROWTH-FACTOR-BETA-1 | MESANGIAL CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | Kidney - drug effects | Kidney - pathology | Kidney Diseases - pathology | Humans | Transforming Growth Factor beta1 - metabolism | Kidney Diseases - drug therapy | Immediate-Early Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Proteins - metabolism | Kidney - metabolism | Animals | Signal Transduction - drug effects | Transforming Growth Factor beta - therapeutic use | Fibrosis | Bone Morphogenetic Proteins - therapeutic use | Transforming Growth Factor beta - metabolism | Bone Morphogenetic Protein 7 | Immediate-Early Proteins - antagonists & inhibitors | Connective Tissue Growth Factor | Kidney Diseases - metabolism | Care and treatment | Analysis | Diabetic nephropathies | Development and progression | Bone morphogenetic proteins | Transforming growth factors | Proteins | Bones | Pharmacology | Biomedical research | Kidney diseases
Journal Article
Mediators of Inflammation, ISSN 0962-9351, 2019, Volume 2019, pp. 7025251 - 2
Journal Article
Journal Article
Cellular Signalling, ISSN 0898-6568, 11/2013, Volume 25, Issue 11, pp. 2198 - 2209
While transforming growth factor-β (TGF-β1)-induced SMAD2/3 signaling is a critical event in the progression of chronic kidney disease, the role of non-SMAD... 
PAI-1 | TGF-β1 | Obstructive nephropathy | SMAD signaling | Renal fibrosis | p53 | P53 | Endothelium, Vascular - cytology | Receptor, Epidermal Growth Factor - agonists | Receptor, Epidermal Growth Factor - genetics | Reactive Oxygen Species - metabolism | Endothelium, Vascular - drug effects | Smad3 Protein - metabolism | Tumor Suppressor Protein p53 - genetics | Renal Insufficiency, Chronic - metabolism | Toluene - analogs & derivatives | Smad3 Protein - genetics | Receptor, Epidermal Growth Factor - metabolism | Isoquinolines - pharmacology | Smad2 Protein - genetics | Renal Insufficiency, Chronic - genetics | Myocytes, Smooth Muscle - drug effects | Toluene - pharmacology | Mink | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Transforming Growth Factor beta1 - pharmacology | Fibroblasts - metabolism | Signal Transduction | Benzothiazoles - pharmacology | Gene Expression Regulation | Smad2 Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Rats | Tyrphostins - pharmacology | Renal Insufficiency, Chronic - pathology | Pyrroles - pharmacology | Serpin E2 - genetics | Animals | Endothelium, Vascular - metabolism | Fibroblasts - drug effects | Fibrosis | Connective Tissue Growth Factor - genetics | Fibroblasts - cytology | Mice | Pyridines - pharmacology | Quinazolines - pharmacology | Serpin E2 - metabolism | Connective Tissue Growth Factor - metabolism
Journal Article