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British Journal of Pharmacology, ISSN 0007-1188, 01/2015, Volume 172, Issue 2, pp. 375 - 387
Several studies suggest that heteromerization between μ (MOP) and δ (DOP) opioid receptors modulates the signalling properties of the individual receptors. For... 
antinociception | heteromer | opioid | high‐throughput screening | dependence | trafficking | signalling | tolerance | high-throughput screening | Receptors, Opioid, delta - metabolism | Animals | Pain - drug therapy | Receptors, Opioid, mu - metabolism | Humans | Protein Multimerization | Ligands | Pain - metabolism | Opioids | Themed Section | New Pathways to Functional Selectivity
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2006, Volume 148, Issue 4, pp. 387 - 395
1 Several studies have described functional interactions between opioid and cannabinoid receptors; the underlying mechanism(s) have not been well explored. One... 
oligomerization | dimerization | Morphine | GPCR | marijuana | neuritogenesis | THC | Neuritogenesis | Oligomerization | Marijuana | Dimerization | Papers
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 9, p. e0184228
There are many factors which make canine cancer like cancer in humans. The occurrence of spontaneous mammary tumors in pet dogs, tumor genetics, molecular... 
BREAST-CANCER | ORPHAN NUCLEAR RECEPTORS | GENE | MODELS | MULTIDISCIPLINARY SCIENCES | ESTROGEN-RELATED-RECEPTOR | GROWTH | ALPHA | MATERNAL STILBESTROL THERAPY | ERR-GAMMA | EXPRESSION | Cell Proliferation | Dog Diseases - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Cells, Cultured | Animals | BRCA2 Protein - metabolism | Flow Cytometry | Cell Cycle | BRCA1 Protein - metabolism | Mammary Neoplasms, Animal - metabolism | Ploidies | Dogs | Cell Line, Tumor | Estrogen Receptor alpha - metabolism | Female | Primary Cell Culture | Real-Time Polymerase Chain Reaction | Cell culture | Usage | Development and progression | Breast cancer | Genetic aspects | Research | Methods | Fibroblast growth factor | Biotechnology | Veterinary colleges | Carcinoma | Laboratories | Estrogens | Genistein | Estrogen receptors | Oncology | Adenoma | Veterinary medicine | Risk factors | Ecological risk assessment | Receptors | Toxicology | Transgenic animals | Rodents | Cell cycle | Genetics | Mammary gland | Growth factors | Chromosomes | Fibroblast growth factor receptor 2 | Players | BRCA2 protein | Medical research | BRCA1 protein | Animal sciences | Health risks | Cultures | Risk analysis | Gene expression | Nuclear receptors | Orphan nuclear receptors | Environmental risk | Pets | Pathology | GATA-3 protein | Hypoxia | Ligands | Prostate cancer | Tumors | Cancer | Fibroblast growth factor receptors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2004, Volume 101, Issue 14, pp. 5135 - 5139
Opiates such as morphine are the choice analgesic in the treatment of chronic pain. However their long-term use is limited because of the development of... 
Analgesia | Biological Sciences | Receptors | Spinal cord | Opioid receptors | Drug interactions | Ligands | Morphine | Agonists | Methadone | CHO cells
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 01/2015, Volume 172, Issue 2, pp. 375 - 387
Several studies suggest that heteromerization between (MOP) and (DOP) opioid receptors modulates the signalling properties of the individual receptors. For... 
METHIONINE ENKEPHALIN | antinociception | heteromer | opioid | high-throughput screening | PROTEIN-COUPLED RECEPTORS | SPINAL-CORD | NEUROBLASTOMA-CELL-LINE | MICE LACKING | CONCISE GUIDE | BIVALENT LIGANDS | dependence | PHARMACOLOGY & PHARMACY | trafficking | signalling | tolerance | MORPHINE-INDUCED ANALGESIA | IRRITABLE-BOWEL-SYNDROME | OPIATE RECEPTORS
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2015, Volume 172, Issue 2, pp. 375 - 387
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2014, Volume 171, Issue 18, pp. 4155 - 4176
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 12/2017, Volume 42, Issue 13, pp. 2527 - 2536
Studies show that neuropeptide-receptor systems in the basolateral amygdala (BLA) play an important role in the pathology of anxiety and other mood disorders.... 
LOCALIZATION | CONTRIBUTE | PSYCHIATRY | RESILIENCE | NEUROSCIENCES | NEUROPEPTIDE-Y | PROTEIN-COUPLED RECEPTOR | NUCLEUS | PHARMACOLOGY & PHARMACY | MICE | STRESS | BRAIN | MODULATION | Motor Activity - physiology | Cricetulus | Receptors, G-Protein-Coupled - metabolism | Fear - drug effects | Motor Activity - drug effects | Arcuate Nucleus of Hypothalamus - cytology | Male | Neurons - cytology | Basolateral Nuclear Complex - cytology | Fear - physiology | Arcuate Nucleus of Hypothalamus - drug effects | Neurons - metabolism | Neurons - drug effects | Anxiety - metabolism | Basolateral Nuclear Complex - drug effects | CHO Cells | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Tissue Culture Techniques | Arcuate Nucleus of Hypothalamus - metabolism | Mice, Inbred C57BL | Models, Molecular | Rats | Mice, Transgenic | Neuropeptides - metabolism | Agouti-Related Protein - metabolism | Basolateral Nuclear Complex - metabolism | Feeding Behavior - physiology | Feeding Behavior - drug effects | Animals | Receptors, G-Protein-Coupled - antagonists & inhibitors | Amygdala | Mental disorders | Neurons | Arcuate nucleus | Disorders | Homology | Neuropeptides | Activation | Fear conditioning | Fear | Mood | Anxieties | Pyramidal cells | Anxiety | Behavior | Conditioning | Hyperpolarization | Original
Journal Article
Current Protocols in Pharmacology, ISSN 1934-8282, 12/2016, Volume 2016, pp. 2.16.1 - 2.16.31
Although G protein-coupled receptor (GPCR) heteromerization has been extensively demonstrated in vitro using heterologous cells that overexpress epitope-tagged... 
Receptor heteromers | G-protein coupled receptors | Dimerization | In situ proximity ligation assay | Molecular Probe Techniques | Animals | Receptors, G-Protein-Coupled - analysis | Humans | Protein Multimerization | Mice | Receptors, G-Protein-Coupled - chemistry | Protein Interaction Mapping
Journal Article