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ELIFE, ISSN 2050-084X, 08/2019, Volume 8
Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular... 
SYSTEM | MATTER | MICROGLIA | INFLAMMATION | DISEASE | BIOLOGY | NEURODEGENERATION | PATTERNS | BLOOD-BRAIN-BARRIER | SUBSET | T-CELLS
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2787 - 2799
Innate immune responses provoke the accumulation of leukocytes at sites of inflammation. In addition to monocytes and granulocytes, B cells also participate in... 
LISTERIA-MONOCYTOGENES | TUMOR-NECROSIS-FACTOR | INTESTINAL IMMUNITY | LYMPHOID-TISSUES | ENDOTHELIAL-CELLS | FOLLICULAR DENDRITIC CELLS | DOMAIN 1-DEPENDENT MANNER | GERMINAL CENTER | LYMPHOTOXIN-ALPHA | DEFICIENT MICE | IMMUNOLOGY | Receptors, CCR6 - immunology | Tumor Necrosis Factor-alpha - metabolism | Chemokine CCL20 - metabolism | Diaminopimelic Acid - pharmacology | Spleen - immunology | Tumor Necrosis Factor-alpha - genetics | Male | Bone Marrow Transplantation - methods | Nod1 Signaling Adaptor Protein - metabolism | Lymphoid Tissue - immunology | Chemokine CCL20 - immunology | Flow Cytometry | Bone Marrow Cells - immunology | Receptors, CCR6 - metabolism | Tumor Necrosis Factor-alpha - immunology | Bone Marrow Cells - drug effects | Female | Neutrophils - metabolism | B-Lymphocytes - metabolism | Cell Line | Mice, Inbred C57BL | Neutrophils - drug effects | Cells, Cultured | Neutrophils - immunology | Lymphoid Tissue - metabolism | Spleen - cytology | Nod1 Signaling Adaptor Protein - immunology | Mice, Knockout | B-Lymphocytes - drug effects | Lymphoid Tissue - cytology | Animals | B-Lymphocytes - immunology | Transplantation Chimera - blood | Diaminopimelic Acid - analogs & derivatives | Spleen - metabolism | Receptors, CCR6 - genetics | Lymphocyte Count | Mice | Bone Marrow Cells - metabolism | Microscopy, Fluorescence | Nod1 Signaling Adaptor Protein - genetics
Journal Article
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2014, Volume 25, Issue 2, pp. 77 - 81
Abstract This special issue of the Cytokine and Growth Factors Review is devoted to highlighting the exceptional science that was presented at the 14th... 
Advanced Basic Science | Autoimmunity | Signaling | TNF (Tumor Necrosis Factor) | TNFSF (Tumor Necrosis Factor Superfamily) | Fibrosis | Cancer | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2018, Volume 34, Issue S1, pp. 1 - 407
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2013, Volume 4, p. 94
Our immune system bears the tremendous task of mounting effective anti-microbial responses whilst maintaining immunoregulatory functions to avoid autoimmunity.... 
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 08/2003, Volume 3, Issue 8, pp. 642 - 655
Journal Article
Immunological Reviews, ISSN 0105-2896, 11/2011, Volume 244, p. 85
Generating an immune response tailored to destroy an infecting organism while limiting bystander damage involves guiding T-cell activation using a variety of... 
Autoimmunity | Antigens | Immune response | Dendritic cells | T cells
Journal Article
Gut Microbes, ISSN 1949-0976, 09/2014, Volume 5, Issue 5, pp. 652 - 662
The intestinal mucosa harbors the largest population of antibody (Ab)-secreting plasma cells (PC) in the human body, producing daily several grams of... 
B cell | intestinal microbiota | immunoglobulin A (IgA) | innate immune recognition | inducible nitric oxide synthase (iNOS) | mucosa | plasma cell
Journal Article
Nature Immunology, ISSN 1529-2908, 09/2013, Volume 14, Issue 9, pp. 937 - 948
Defense against attaching-and-effacing bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce protective mucosal responses.... 
NATURAL-KILLER-CELLS | STEM-CELLS | SIGNALING CONTROLS | ROR-GAMMA-T | IN-VIVO | INNATE LYMPHOID-CELLS | LY6C(HI) MONOCYTES | DIFFERENTIATION | IMMUNOLOGY | CITROBACTER-RODENTIUM | KNOCKOUT MICE | Intestinal Mucosa - metabolism | Spleen - immunology | Minor Histocompatibility Antigens | Dendritic Cells - immunology | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | Enterobacteriaceae Infections - immunology | Lymphotoxin beta Receptor - metabolism | Cell Differentiation - genetics | Lectins, C-Type - metabolism | Interleukin-23 - metabolism | Intestinal Mucosa - immunology | Wound Healing - genetics | Dendritic Cells - metabolism | Citrobacter rodentium - immunology | Signal Transduction | Enterobacteriaceae Infections - microbiology | Enterobacteriaceae Infections - mortality | Receptor, Notch2 - metabolism | Receptors, Cell Surface - metabolism | Mice, Transgenic | Intestinal Mucosa - microbiology | Transcription Factors - genetics | Wound Healing - immunology | Receptor, Notch2 - deficiency | Transcription Factors - metabolism | Cell Differentiation - immunology | Animals | Host-Pathogen Interactions - genetics | Lymphotoxin beta Receptor - genetics | Dendritic Cells - cytology | Mice | CD11b Antigen - metabolism | Genetic aspects | Bacterial infections | Research | Dendritic cells | Health aspects | Risk factors
Journal Article
Science, ISSN 0036-8075, 9/2001, Volume 293, Issue 5537, pp. 2111 - 2114
The B cell activating factor BAFF (BlyS/TALL-1/zTNF4) is a tumor necrosis factor (TNF)-related ligand that promotes B cell survival and binds to three... 
T lymphocytes | Spleen | Antigens | Receptors | B lymphocytes | Developmental biology | Antibodies | Antigen presenting cells | Ligands | Reports | Mice | MULTIDISCIPLINARY SCIENCES | NECROSIS-FACTOR FAMILY | GROWTH | FACTOR RECEPTOR SUPERFAMILY | MICE | MOUSE BONE-MARROW | IDENTIFICATION | AUTOIMMUNE-DISEASE | MEMBER | APRIL | LYMPHOCYTES | Spleen - immunology | Mice, Inbred A | Tumor Necrosis Factor-alpha - genetics | B-Lymphocyte Subsets - cytology | Tumor Necrosis Factor-alpha - deficiency | Receptors, Tumor Necrosis Factor - physiology | Lymphoid Tissue - immunology | Antigens, CD - analysis | Membrane Proteins - deficiency | Flow Cytometry | Membrane Proteins - physiology | Immunoglobulins - blood | B-Lymphocyte Subsets - immunology | Receptors, Tumor Necrosis Factor - deficiency | Receptors, Tumor Necrosis Factor - genetics | B-Lymphocyte Subsets - physiology | B-Lymphocytes - cytology | Leukopoiesis | Signal Transduction | Bone Marrow Cells - cytology | Cell Separation | Cell Survival | Membrane Proteins - genetics | Thymus Gland - cytology | B-Lymphocytes - physiology | Spleen - cytology | Lymph Nodes - immunology | Lymph Nodes - cytology | Mice, Knockout | B-Cell Maturation Antigen | Lymphoid Tissue - cytology | Phenotype | Animals | B-Cell Activating Factor | B-Lymphocytes - immunology | Tumor Necrosis Factor-alpha - physiology | Lymphocyte Count | Thymus Gland - immunology | Cytology | B cells | Research | Cellular biology | Cells | Tumors
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2015, Volume 6, p. 657
Collections of leukocytes in the meningeal space have been documented in Multiple Sclerosis (MS). These meningeal aggregates, which in the context of other... 
Journal Article
Immunity, ISSN 1074-7613, 12/2015, Volume 43, Issue 6, pp. 1160 - 1173
Journal Article