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Experimental Hematology, ISSN 0301-472X, 08/2019, Volume 76, pp. S78 - S79
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7626, pp. 477 - 482
Avoidance of apoptosis is critical for the development and sustained growth of tumours. The pro-survival protein myeloid cell leukemia 1 (MCL1) is... 
MULTIPLE-MYELOMA | SURVIVAL | ANTI-APOPTOTIC MCL-1 | PROTEIN | DEPENDENCY | BCL-XL | MULTIDISCIPLINARY SCIENCES | HIGH-AFFINITY | TUMOR-CELLS | COMBINATION | NAVITOCLAX | Neoplasms - metabolism | Thiophenes - therapeutic use | Leukemia - pathology | Apoptosis - drug effects | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Male | Antineoplastic Agents - therapeutic use | Leukemia - metabolism | Thiophenes - administration & dosage | Antineoplastic Agents - administration & dosage | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Lymphoma - metabolism | Lymphoma - drug therapy | Multiple Myeloma - drug therapy | Myeloid Cell Leukemia Sequence 1 Protein - chemistry | Female | Lymphoma - pathology | Antineoplastic Agents - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Pyrimidines - administration & dosage | bcl-2-Associated X Protein - metabolism | Leukemia - drug therapy | Models, Molecular | Thiophenes - pharmacology | Pyrimidines - pharmacology | Multiple Myeloma - metabolism | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Multiple Myeloma - pathology | Animals | Models, Biological | Pyrimidines - therapeutic use | Cell Line, Tumor | Mice | Neoplasms - pathology | Myelocytic leukemia | Physiological aspects | Nonlymphoid leukemia | Metastasis | Observations | Health aspects | Apoptosis | Proteins | Studies | Multiple myeloma | Cytotoxicity | Kinases | Drug dosages | Tumors | Cancer | Crystal structure | Index Medicus
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2017, Volume 9, Issue 401, p. eaam7049
Journal Article
Jisuanji Kexue = Computer Science, ISSN 1002-137X, 01/2017, Volume 44, Issue 9
Users on geo-social networks may want to find the other users with the same interests,motivated by which,we proposed a new type of spatial query named... 
User groups | Queries | Algorithms | Ranking | Query processing | Pruning | Social networks
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2385 - 10
Venetoclax is a first-in-class cancer therapy that interacts with the cellular apoptotic machinery promoting apoptosis. Treatment of patients suffering chronic... 
Therapy | Chronic lymphatic leukemia | Bcl-2 protein | Leukemia | Mutation | Binding sites | Crystal structure | Apoptosis | Index Medicus
Journal Article
Cancer Discovery, ISSN 2159-8274, 03/2019, Volume 9, Issue 3, pp. 342 - 353
The BCL2 inhibitor venetoclax induces high rates of durable remission in patients with previously treated chronic lymphocytic leukemia (CLL). However, despite... 
APOPTOSIS | CLL | ONCOLOGY | RITUXIMAB | FAMILY PROTEINS | INHIBITOR | ABT-199
Journal Article
Ruan Jian Xue Bao/Journal of Software, ISSN 1000-9825, 09/2017, Volume 28, Issue 9, pp. 2402 - 2430
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5361 - 10
Combining whole exome sequencing, transcriptome profiling, and T cell repertoire analysis, we investigate the spatial features of surgically-removed biopsies... 
CTLA-4 BLOCKADE | MULTICENTER | EVOLUTION | PD-1 BLOCKADE | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | OPEN-LABEL | ATEZOLIZUMAB | NIVOLUMAB | DOCETAXEL | TUMORS | Toxicity | Lung cancer | Non-small cell lung carcinoma | Cytotoxicity | Lymphocytes T | Gene expression | Loci | Heterogeneity | Immunology | Biopsy | Lymphocytes | Spatial heterogeneity | Tumors | Cancer | Index Medicus
Journal Article
International Immunopharmacology, ISSN 1567-5769, 03/2018, Volume 56, pp. 105 - 112
Oxyresveratrol (Oxy) is a natural polyhydroxystilbene abundant in mulberry that has anti-inflammation and anti-oxidant activities. We evaluated the protective... 
Oxyresveratrol | Keap1-Nrf2 | Anti-apoptosis | Acute liver injury | Lipopolysaccharide/d-galactosamine | TLR4/NF-κB | Lipopolysaccharide/D-galactosamine | TLR4/NF-kappa B | APOPTOSIS | RESVERATROL | OXIDATIVE STRESS | ACTIVATION | IMMUNOLOGY | CELL-DEATH | IN-VITRO | SIGNALING PATHWAY | HEPATIC-FAILURE | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | MOLECULAR-MECHANISMS | Heme Oxygenase-1 - metabolism | Liver - pathology | Stilbenes - therapeutic use | Male | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Galactosamine - immunology | Morus - immunology | Liver - drug effects | Anti-Inflammatory Agents - therapeutic use | Membrane Proteins - metabolism | Hepatocytes - drug effects | Hepatocytes - physiology | Liver - metabolism | Cells, Cultured | Kelch-Like ECH-Associated Protein 1 - metabolism | Mice, Inbred Strains | Toll-Like Receptor 4 - metabolism | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Chemical and Drug Induced Liver Injury - drug therapy | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Plant Extracts - therapeutic use | Apoptosis | Prevention | Evaluation | Enzymes | Biological products | Liver | Heme | Lymphomas | Mitogens | Oxidative stress | Bax protein | Bcl-2 protein | Product inhibition | Oxidoreductase | AKT protein | Activation | Lipopolysaccharides | Proteins | Signal transduction | Rodents | Aspartate transaminase | Toll-like receptors | Pretreatment | NF-κB protein | Alanine | Cytokines | Pharmacology | Inflammation | TLR4 protein | Chemical compounds | Quinine | Lymphoma | 1-Phosphatidylinositol 3-kinase | Immune systems | Oxygenase | Signaling | Injury prevention | D-Galactosamine | Lymphocytes B | Alanine transaminase | B-cell lymphoma | Index Medicus
Journal Article
Applied Mechanics and Materials, ISSN 1660-9336, 2014, Volume 513-517, Issue Applied Science, Materials Science and Information Technologies in Industry, pp. 994 - 998
  This paper mainly discusses the Multiple Constrained Qos Routing Algorithm, in the analysis of the basic on the basis of mathematical model of Qos routing.... 
Multiple constrained | Objective function | Qos routing | Ant colony algorithm | Ant colony optimization | Constraints | Algorithms | Computer simulation | Mathematical analysis | Mathematical models | Quality of service architectures | Optimization
Conference Proceeding
Hangkong Dongli Xuebao/Journal of Aerospace Power, ISSN 1000-8055, 2014, Volume 29, Issue 2, pp. 420 - 426
Journal Article