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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 19, pp. 2086 - 2096
Abstract Background Brugada syndrome (BrS), a disorder associated with characteristic electrocardiogram precordial ST-segment elevation, predisposes afflicted... 
Cardiovascular | Internal Medicine | genome editing | Ca2+ transient | SCN5A | action potential | arrhythmia | gene expression | transient | RECAPITULATE | CARDIAC & CARDIOVASCULAR SYSTEMS | SEGMENT ELEVATION | CARDIOTOXICITY | MECHANISMS | LONG-QT SYNDROME | DILATED CARDIOMYOPATHY | MODELS | MUTATION | SUDDEN CARDIAC DEATH | ASSOCIATION | Brugada Syndrome - genetics | Humans | Middle Aged | Male | RNA - genetics | Young Adult | Brugada Syndrome - metabolism | Brugada Syndrome - pathology | Polymerase Chain Reaction | Electrocardiography | Adult | Cell Differentiation | NAV1.5 Voltage-Gated Sodium Channel - genetics | Induced Pluripotent Stem Cells - cytology | NAV1.5 Voltage-Gated Sodium Channel - biosynthesis | Induced Pluripotent Stem Cells - metabolism | Heart Conduction System - pathology | Myocytes, Cardiac - cytology | Gene Expression Regulation | Genotype | Phenotype | Heart Conduction System - physiopathology | Pedigree | Adolescent | Myocytes, Cardiac - metabolism | Heart | Medical colleges | Analysis | Electrocardiogram | Genomics | Stem cells | Genetic aspects | Cardiology | Cardiovascular agents | Cardiomyopathy | Editing | Cardiomyocytes | Genomes | Family medical history | Gene expression | Patients | Cell adhesion & migration | Studies | Genotype & phenotype | Hypotheses | Sodium | Fibroblasts | Genetic engineering | Mutation | Methods | cardiomyocytes | Induced pluripotent stem cells | Brugada Syndrome
Journal Article
by Zewinger, Stephen, MD and Kleber, Marcus E, PhD and Tragante, Vinicius, PhD and McCubrey, Raymond O, MS and Schmidt, Amand F, MPH and Direk, Kenan, MD and Laufs, Ulrich, Prof and Werner, Christian, MD and Koenig, Wolfgang, MD and Rothenbacher, Dietrich, Prof and Mons, Ute, PD and Breitling, Lutz P, MD and Brenner, Herrmann, Prof and Jennings, Richard T, PhD and Petrakis, Ioannis, MD and Triem, Sarah, MSc and Klug, Mira, MSc and Filips, Alexandra, MD and Blankenberg, Stefan, Prof and Waldeyer, Christoph, MD and Sinning, Christoph, MD and Schnabel, Renate B, MD and Lackner, Karl J, Prof and Vlachopoulou, Efthymia, PhD and Nygård, Ottar, Prof and Svingen, Gard Frodahl Tveitevåg, MD and Pedersen, Eva Ringdal, MD and Tell, Grethe S, Prof and Sinisalo, Juha, Prof and Nieminen, Markku S, Prof and Laaksonen, Reijo, Prof and Trompet, Stella, PhD and Smit, Roelof A J, MD and Sattar, Naveed, Prof and Jukema, J Wouter, Prof and Groesdonk, Heinrich V, MD and Delgado, Graciela, MSc and Stojakovic, Tatjana, MD and Pilbrow, Anna P, PhD and Cameron, Vicky A, Prof and Richards, A Mark, Prof and Doughty, Robert N, Prof and Gong, Yan, PhD and Cooper-DeHoff, Rhonda, PharmD and Johnson, Julie, Prof and Scholz, Markus, Prof and Beutner, Frank, MD and Thiery, Joachim, Prof and Smith, J Gustav, MD and Vilmundarson, Ragnar O, MSc and McPherson, Ruth, Prof and Stewart, Alexandre F R, Prof and Cresci, Sharon, MD and Lenzini, Petra A, PhD and Spertus, John A, Prof and Olivieri, Oliviero, Prof and Girelli, Domenico, Prof and Martinelli, Nicola I, MD and Leiherer, Andreas, PhD and Saely, Christoph H, Prof and Drexel, Heinz, Prof and Mündlein, Axel, PhD and Braund, Peter S, Prof and Nelson, Christopher P, PhD and Samani, Nilesh J, Prof and Kofink, Daniel, MD and Hoefer, Imo E, MD and Pasterkamp, Gerard, Prof and Quyyumi, Arshed A, Prof and Ko, Yi-An, PhD and Hartiala, Jaana A, PhD and Allayee, Hooman, Prof and Tang, W H Wilson, MD and Hazen, Stanley L, Prof and Eriksson, Niclas, PhD and Held, Claes, MD and Hagström, Emil, MD and Wallentin, Lars, Prof and Åkerblom, Axel, MD and Siegbahn, Agneta, Prof and Karp, Igor, PhD and Labos, Christopher, MD and Pilote, Louise, Prof and Engert, James C, PhD and Brophy, James M, Prof and Thanassoulis, George, MD and Bogaty, Peter, Prof and Szczeklik, Wojciech, Prof and Kaczor, Marcin, MD and Sanak, Marek, Prof and Virani, Salim S, MD and Ballantyne, Christie M, Prof and Lee, Vei-Vei, MD and Boerwinkle, Eric, Prof and Holmes, Michael V, PhD and Horne, Benjamin D, PhD and Hingorani, Aroon, Prof and Asselbergs, Folkert W, Prof and Patel, Riyaz S, MD and Krämer, Bernhard K, Prof and ... and GENIUS-CHD Consortium and GENIUS-CHD consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Kardiologi and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Uppsala universitet and Institutionen för medicinska vetenskaper and Uppsala kliniska forskningscentrum (UCR)
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 2017, Volume 5, Issue 7, pp. 534 - 543
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 386, pp. S11 - S11
Abstract Background High-field intraoperative magnetic resonance imaging (iMRI) has been studied in two single-centre randomised trials with patients who have... 
Internal Medicine
Journal Article
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2011, Volume 124, Issue 7, pp. 614 - 620
Abstract Background There is limited information about the safety of chronic nonsteroidal anti-inflammatory drugs (NSAIDs) in hypertensive patients with... 
Internal Medicine | Hypertension | Myocardial infarction | Nonsteroidal anti-inflammatory drugs | Coronary artery disease | NSAIDs | GASTROINTESTINAL TOXICITY | MYOCARDIAL-INFARCTION | CYCLOOXYGENASE | BLOOD-PRESSURE | TRIAL | MEDICINE, GENERAL & INTERNAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | CYCLO-OXYGENASE-2 INHIBITORS | NAPROXEN | OSTEOARTHRITIS | CARDIOVASCULAR RISK | Multivariate Analysis | Myocardial Infarction - chemically induced | Myocardial Infarction - epidemiology | Myocardial Infarction - mortality | Follow-Up Studies | Humans | Middle Aged | Hypertension - drug therapy | Male | Verapamil - therapeutic use | Multicenter Studies as Topic | Stroke - chemically induced | Adult | Female | Stroke - epidemiology | Blood Pressure - drug effects | Stroke - mortality | Odds Ratio | Myocardial Infarction - etiology | Pyrazoles - adverse effects | Naproxen - adverse effects | Drug Administration Schedule | Diclofenac - adverse effects | Kaplan-Meier Estimate | Proportional Hazards Models | Celecoxib | Coronary Artery Disease - drug therapy | Antihypertensive Agents - therapeutic use | Randomized Controlled Trials as Topic | Stroke - etiology | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Confounding Factors (Epidemiology) | Coronary Artery Disease - complications | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Hypertension - complications | Sulfonamides - adverse effects | Indoles - therapeutic use | Aged | Ibuprofen - adverse effects
Journal Article
Journal of Pediatrics, The, ISSN 0022-3476, 2013, Volume 163, Issue 3, pp. 686 - 691
Objective To determine whether cytochrome P 450CYP 2C19 haplotype associates with lansoprazole-associated adverse event frequency. Study design Respiratory... 
Pediatrics | Sore throat | Poor metabolizer | SNP | Upper respiratory tract infection | Cytochrome P450 | PPI | CYP | Single nucleotide polymorphism | Extensive metabolizer | Wild type | URI | Proton pump inhibitor | COMMUNITY-ACQUIRED PNEUMONIA | INFECTIONS | METAANALYSIS | GASTROESOPHAGEAL-REFLUX DISEASE | PHARMACOGENOMICS | PROTON PUMP INHIBITORS | RISK | ASTHMA | PEDIATRICS | BACTERIAL OVERGROWTH | SECRETION | Haplotypes | Bronchitis - genetics | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Male | Genotyping Techniques | Pharyngitis - chemically induced | Respiratory Tract Infections - genetics | Pharyngitis - genetics | 2-Pyridinylmethylsulfinylbenzimidazoles - therapeutic use | Respiratory Tract Infections - chemically induced | Female | Odds Ratio | Child | Bronchitis - chemically induced | Proton Pump Inhibitors - adverse effects | 2-Pyridinylmethylsulfinylbenzimidazoles - pharmacokinetics | 2-Pyridinylmethylsulfinylbenzimidazoles - adverse effects | Logistic Models | Genetic Markers | Proton Pump Inhibitors - therapeutic use | Asthma - drug therapy | Asthma - genetics | Proton Pump Inhibitors - pharmacokinetics | Cytochrome P-450 CYP2C19 | Adolescent | Polymorphism, Single Nucleotide | Lansoprazole | Complications and side effects | Medical colleges | Pharmacogenetics | Cytochrome P-450 | Drugstores | Genetic aspects
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 61, Issue 9, pp. 957 - 970
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2007, Volume 99, Issue 2, pp. 250 - 255
Heart failure (HF) is characterized by neurohormonal activation of the sympathetic nervous and renin-angiotensin systems. Genetic polymorphisms in these... 
Cardiovascular
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 64, Issue 8, pp. 784 - 793
Abstract Background The 2014 Eighth Joint National Committee panel recommendations for management of high blood pressure (BP) recommend a systolic BP threshold... 
Cardiovascular | Internal Medicine | coronary artery disease | blood pressure | systolic | elderly | target | Hypertension | Blood pressure | Coronary heart disease | Pharmacy | Heart failure | Heart attacks | Sensitivity analysis | Mortality | Cardiovascular disease | Confidence intervals | Variables | Older people | Diabetes | Drug therapy | Age
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology: In Practice, ISSN 2213-2198, 2015, Volume 4, Issue 1, pp. 147 - 148.e1
  [...]we evaluated longitudinal variability by analyzing quality control measurements from healthy technicians who would not be expected to have elevated or... 
Internal Medicine | Allergy and Immunology | ALLERGY | IMMUNOLOGY | Asthma - diagnosis | Time Factors | Breath Tests - instrumentation | Humans | Female | Male | Exhalation | Adrenal Cortex Hormones - therapeutic use | Nitric Oxide - metabolism | Asthma - drug therapy | Biomarkers, Pharmacological - metabolism | Observer Variation | Studies | Inflammation | Quality control | Asthma
Journal Article