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Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 8, pp. 908 - 918
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 9, pp. 954 - 965
Summary Background Addition of a MEK inhibitor to a BRAF inhibitor enhances tumour growth inhibition, delays acquired resistance, and abrogates paradoxical... 
Hematology, Oncology and Palliative Medicine
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 8, pp. 782 - 789
Summary Background MEK is a member of the MAPK signalling cascade that is commonly activated in melanoma. Direct inhibition of MEK blocks cell proliferation... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | BRAF | ONCOLOGY | RAF | SOMATIC MUTATIONS | PROGRESSION | Skin Neoplasms - drug therapy | United States | Humans | Middle Aged | Melanoma - enzymology | Male | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Molecular Targeted Therapy | Uveal Neoplasms - enzymology | Young Adult | Pyridones - administration & dosage | Skin Neoplasms - enzymology | Time Factors | Antineoplastic Agents - adverse effects | DNA Mutational Analysis | Melanoma - genetics | Skin Neoplasms - mortality | Adult | Female | Skin Neoplasms - pathology | MAP Kinase Kinase 1 - antagonists & inhibitors | Uveal Neoplasms - genetics | Uveal Neoplasms - pathology | Drug Administration Schedule | Administration, Oral | Pyrimidinones - adverse effects | Kaplan-Meier Estimate | MAP Kinase Kinase 1 - metabolism | Treatment Outcome | MAP Kinase Kinase 2 - metabolism | Melanoma - pathology | Uveal Neoplasms - drug therapy | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | MAP Kinase Kinase 2 - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Skin Neoplasms - genetics | Uveal Neoplasms - mortality | Aged | Pyrimidinones - administration & dosage | Mutation | Pyridones - adverse effects | Melanoma - mortality | Prevention | Care and treatment | Melanoma | Cancer | Index Medicus
Journal Article
by Burtness, Barbara and Harrington, Kevin J and Harrington, Kevin and Greil, Richard and Soulières, Denis and Tahara, Makoto and de Castro, Gilberto and Psyrri, Amanda and Basté, Neus and Neupane, Prakash and Bratland, Åse and Bratland, Aase and Fuereder, Thorsten and Hughes, Brett G M and Hughes, Brett and Mesía, Ricard and Ngamphaiboon, Nuttapong and Rordorf, Tamara and Wan Ishak, Wan Zamaniah and Hong, Ruey-Long and González Mendoza, René and Roy, Ananya and Zhang, Yayan and Gumuscu, Burak and Cheng, Jonathan D and Jin, Fan and Rischin, Danny and Lerzo, Guillermo and Tatangelo, Marcelo and Varela, Mirta and Zarba, Juan Jose and Boyer, Michael and Gan, Hui and Gao, Bo and Mallesara, Girish and Taylor, Anne and Burian, Martin and Barrios, Carlos Henrique and de Castro Junior, Dalvaro Oliveira and Castro, Gilberto and Franke, Fabio Andre and Girotto, Gustavo and Lima, Iane Pinto Figueiredo and Nicolau, Ulisses Ribaldo and Pinto, Gustavo Dix Junqueira and Santos, Lucas and Victorino, Ana-Paula and Chua, Neil and Couture, Felix and Gregg, Richard and Hansen, Aaron and Hilton, John and McCarthy, Joy and Soulieres, Denis and Ascui, Rodrigo and Gonzalez, Pablo and Villanueva, Luis and Torregroza, Marco and Zambrano, Angela and Holeckova, Petra and Kral, Zdenek and Melichar, Bohuslav and Prausova, Jana and Vosmik, Milan and Andersen, Maria and Gyldenkerne, Niels and Jurgens, Hannes and Putnik, Kadri and Reinikainen, Petri and Gruenwald, Viktor and Laban, Simon and Aravantinos, Gerasimos and Boukovinas, Ioannis and Georgoulias, Vassilis and Kwong, Dora and Al-Farhat, Yousuf and Csoszi, Tibor and Erfan, Jozsef and Horvai, Geza and Landherr, Laszlo and Remenar, Eva and Ruzsa, Agnes and Szota, Judit and Billan, Salem and Gluck, Iris and Gutfeld, Orit and Popovtzer, Aron and Benasso, Marco and Bui, Simona and Ferrari, Vittorio and Licitra, Lisa and Nole, Franco and Fujii, Takashi and Fujimoto, Yasushi and Hanai, Nobuhiro and Hara, Hiroki and Matsumoto, Koji and Mitsugi, Kenji and Monden, Nobuya and Nakayama, Masahiro and ...
The Lancet, ISSN 0140-6736, 11/2019, Volume 394, Issue 10212, pp. 1915 - 1928
Pembrolizumab is active in head and neck squamous cell carcinoma (HNSCC), with programmed cell death ligand 1 (PD-L1) expression associated with improved... 
Chemotherapy | Squamous cell carcinoma | Metastasis | Analysis | Cancer | Medical research | 5-Fluorouracil | Mortality | Oncology | Survival | Metastases | Population (statistical) | Pembrolizumab | Hypotheses | Randomization | Motivation | Platinum | Cell death | PD-L1 protein | Population | Head and neck cancer | Ligands | Larynx | Safety | Apoptosis
Journal Article
Respiration, ISSN 0025-7931, 12/2012, Volume 85, Issue 1, pp. V - V
  No abstract available [PUBLICATION ABSTRACT] 
Obituary
Journal Article
Lancet, The, ISSN 0140-6736, 2008, Volume 371, Issue 9629, pp. 1999 - 2012
Journal Article
Journal Article
by Vranckx, Pascal and Valgimigli, Marco and Jüni, Peter and Hamm, Christian and Steg, Philippe Gabriel and Steg, Gabriel and Heg, Dik and van Es, Gerrit Anne and McFadden, Eugene P and McFadden, Eugene and Onuma, Yoshinobu and van Meijeren, Cokky and Chichareon, Ply and Benit, Edouard and Möllmann, Helge and Janssens, Luc and Ferrario, Maurizio and Moschovitis, Aris and Zurakowski, Aleksander and Dominici, Marcello and Van Geuns, Robert Jan and Huber, Kurt and Slagboom, Ton and Serruys, Patrick and Serruys, Patrick W and Windecker, Stephan and Abdellaoui, Mohamed and Adlam, David and Akin, Ibrahim and Albarran Gonzalez-Trevilla, Agustin and Almeida, Manuel and Alves Lemos Neto, Pedro and Aminian, Adel and Anderson, Richard and Andreae, Rick and Angioi, Michael and Asano, Taku and Barbato, Emanuele and Barlis, Peter and Barraud, Pascal and Bertrand, Olivier and Beygui, Farzin and Bolognese, Leonardo and Botelho, Roberto and Bouwman, Coby and Bressers, Marco and Brunel, Philippe and Buszman, Pawel and Buysschaert, Ian and Canas da Silva, Pedro and Carrie, Didier and Cequier, Angel and Chin Chang, Chun and Chowdhary, Saqib and Collet, Carlos and Colombo, Antonio and Cotton, James and Cruz Ferreira, Rui and Curello, Salvatore and Curzen, Nick and de Bot, Judith and de Vreede, Tone and Delle Karth, Georg and Dijksma, Lynn and Édes, István and Eeckhout, Eric and Eitel, Ingo and Faluközy, József and Fath-Ordoubadi, Farzin and Fontos, Geza and Francisco Diaz, Jose and Freitas Quintella, Edgard and Frey, Bernhard and Friedrich, Guy and Galasko, Gavin and Galuszka, Grzegorz and Gama Ribeiro, Vasco and Garg, Scot and Gargiulo, Giuseppe and Geisler, Tobias and Gelev, Valeri and Ghandilyan, Art and Goicolea, Javier and Gori, Tommaso and Gragnano, Felice and Guimarães, Ana and Haude, Michael and Heijke, Pieter and Hernández Antolin, Rosa Ana and Hildick-Smith, David and Hillen, Dorien and Hoekman, Ina and Hofma, Sjoerd and Holmvang, Lene and Hoole, Stephen and Horváth, Iván and Hugense, Annemarie and Ibrahim, Karim and Iñiguez, Andres and Isaaz, Karl and ... and GLOBAL LEADERS Investigators
The Lancet, ISSN 0140-6736, 09/2018, Volume 392, Issue 10151, pp. 940 - 949
We hypothesised that ticagrelor, in combination with aspirin for 1 month, followed by ticagrelor alone, improves outcomes after percutaneous coronary... 
DEFINITIONS | MEDICINE, GENERAL & INTERNAL | BIODEGRADABLE POLYMER | METAANALYSIS | DUAL-ANTIPLATELET THERAPY | MYOCARDIAL-INFARCTION | ACADEMIC RESEARCH CONSORTIUM | CLINICAL-TRIALS | ACUTE CORONARY SYNDROMES | DURABLE POLYMER | INTERVENTION | Myocardial Infarction - mortality | Purinergic P2Y Receptor Antagonists - administration & dosage | Humans | Middle Aged | Male | Coronary Artery Disease - drug therapy | Coronary Artery Disease - mortality | Adenosine - administration & dosage | Ticlopidine - analogs & derivatives | Aspirin - administration & dosage | Drug-Eluting Stents - adverse effects | Coronary Angiography | Adenosine - analogs & derivatives | Platelet Aggregation Inhibitors - administration & dosage | Intention to Treat Analysis | Ticlopidine - administration & dosage | Clopidogrel | Female | Aged | Myocardial Infarction - prevention & control | Drug Therapy, Combination | Ticagrelor | Percutaneous Coronary Intervention | Aggregation | Blood platelets | Analysis | Myocardial infarction | Intervention | Therapy | Surgical implants | Heart attacks | Disorders | Cardiovascular disease | Drug delivery | Bleeding | Subgroups | Consortia | Randomization | Motivation | Implants | Heart diseases | Stents | Drug dosages | Aspirin | Stroke | Mortality | Coronary artery | Implantation | Coronary artery disease | Patients | Coronary vessels | Fatalities | Infarction | Acute coronary syndromes | Biosensors
Journal Article
04/2018
JINST 13 (2018) P06015 The CMS muon detector system, muon reconstruction software, and high-level trigger underwent significant changes in 2013-2014 in... 
Journal Article
Journal of High Energy Physics (Online), ISSN 1029-8479, 05/2018, Volume 2018, Issue 11
JHEP 11 (2018) 042 A search in energetic, high-multiplicity final states for evidence of physics beyond the standard model, such as black holes, string balls,... 
Physics - High Energy Physics - Experiment | Beyond Standard Model | Hadron-Hadron scattering (experiments) | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
Journal Article
Brain Structure and Function, ISSN 1863-2653, 7/2018, Volume 223, Issue 6, pp. 2767 - 2783