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1. Full Text Platelet 12-LOX scores a HIT
by Goodall, Alison H
Blood, ISSN 0006-4971, 10/2014, Volume 124, Issue 14, pp. 2166 - 2168
Life Sciences & Biomedicine | Hematology | Science & Technology | Animals | Arachidonate 12-Lipoxygenase - metabolism | Blood Platelets - metabolism | Humans | Receptors, IgG - metabolism | Index Medicus | Abridged Index Medicus
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2. Full Text Common variants near TERC are associated with mean telomere length
by Codd, Veryan and Mangino, Massimo and van der Harst, Pim and Braund, Peter S and Kaiser, Michael and Beveridge, Alan J and Rafelt, Suzanne and Moore, Jasbir and Nelson, Chris and Soranzo, Nicole and Zhai, Guangju and Valdes, Ana M and Blackburn, Hannah and Mateo Leach, Irene and de Boer, Rudolf A and Goodall, Alison H and Ouwehand, Willem and van Veldhuisen, Dirk J and van Gilst, Wiek H and Navis, Gerjan and Burton, Paul R and Tobin, Martin D and Hall, Alistair S and Thompson, John R and Spector, Tim and Samani, Nilesh J and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium
Nature genetics, ISSN 1061-4036, 03/2010, Volume 42, Issue 3, pp. 197 - 199
HUMANS | GENERAL-POPULATION | LEUCINE-RICH REPEAT | LOCUS | UMCG Approved | GENOME-WIDE ASSOCIATION | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | RNA - physiology | Genome-Wide Association Study | Meta-Analysis as Topic | Age Factors | Gene Frequency | Humans | Polymorphism, Single Nucleotide - physiology | RNA - genetics | Chromosomes, Human, Pair 3 | Telomerase - genetics | Aging - genetics | Telomerase - physiology | Time Factors | Telomere - metabolism | Quantitative Trait Loci | Cohort Studies | Telomere - genetics | Physiological aspects | Telomeres | Genetic aspects | Structure | Genetic variation | Aging | Genetics | Gene therapy | Chromosomes | Apoptosis | Index Medicus
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3. Full Text Telomere shortening in atherosclerosis
by Samani, Nilesh J and Boultby, Rachel and Butler, Robert and Thompson, John R and Goodall, Alison H
The Lancet (British edition), ISSN 0140-6736, 08/2001, Volume 358, Issue 9280, pp. 472 - 473
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Medical sciences | Coronary heart disease | Leukocytes - ultrastructure | Telomere - ultrastructure | Cellular Senescence | Humans | Middle Aged | Coronary Artery Disease - genetics | Coronary Artery Disease - pathology | Adult | Female | Male | Aged | Case-Control Studies | Physiological aspects | Telomeres | Eukaryotic cells | Atherosclerosis | Clinical trials | Medical research | Cardiovascular disease | Genes | Coronary vessels | Senescence | Pathogenesis | Base pairs | Coronary artery | Cell division | Coronary artery disease | Disease control | Leucocytes | Arteriosclerosis | Aging | Chromosomes | Telomerase | Heart diseases | Age | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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4. Full Text Inorganic phosphate (Pi) signaling in endothelial cells: A molecular basis for generation of endothelial microvesicles in uraemic cardiovascular disease
by Abbasian, Nima and Bevington, Alan and Burton, James O and Herbert, Karl E and Goodall, Alison H and Brunskill, Nigel J
International journal of molecular sciences, ISSN 1661-6596, 10/2020, Volume 21, Issue 19, pp. 1 - 15
Signaling | Inorganic phosphate | Src | Tropomyosin | PP2A | Microvesicles | DAPK-1 | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Actin Cytoskeleton - metabolism | Signal Transduction | Cell-Derived Microparticles - enzymology | Humans | Cardiovascular Diseases - enzymology | Cardiovascular Diseases - pathology | Hyperphosphatemia - pathology | Phosphates - metabolism | Protein Phosphatase 2 - metabolism | Cell-Derived Microparticles - pathology | Cytoskeletal Proteins - metabolism | Actin Cytoskeleton - pathology | Endothelial Cells - pathology | Endothelial Cells - enzymology | Cell Line, Transformed | Hyperphosphatemia - enzymology | Phosphates | Phosphatases | Scientific equipment and supplies industry | Actin | Kidney diseases | Muscle proteins | Cardiovascular diseases | Health aspects | Cells | Endothelium | Index Medicus | inorganic phosphate | tropomyosin | signaling
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5. Full Text Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
by Christopher P. Thomas and Lloyd T. Morgan and Benjamin H. Maskrey and Robert C. Murphy and Hartmut Kühn and Stanley L. Hazen and Alison H. Goodall and Hassan A. Hamali and Peter W. Collins and Valerie B. O'Donnell
The Journal of biological chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 10, pp. 6891 - 6903
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - metabolism | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - chemistry | Arachidonate 12-Lipoxygenase - metabolism | Humans | Esters - metabolism | Phosphatidylcholines - chemistry | Phosphatidylcholines - metabolism | Animals | Blood Platelets - metabolism | Esters - chemistry | Signal Transduction - physiology | Molecular Structure | Phosphatidylethanolamines - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Phosphatidylethanolamines - chemistry | Index Medicus | Function | Eicosanoids | Phospholipid | Lipids | Arachidonic Acid | Lipoxygenase Pathway | Lipid
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6. Full Text DNA methylation and body-mass index: A genome-wide analysis
by Dick, Katherine J and Nelson, Christopher P and Tsaprouni, Loukia and Sandling, Johanna K and Aïssi, Dylan and Wahl, Simone and Meduri, Eshwar and Morange, Pierre-Emmanuel and Gagnon, France and Grallert, Harald and Waldenberger, Melanie and Peters, Annette and Erdmann, Jeanette and Hengstenberg, Christian and Cambien, Francois and Goodall, Alison H and Ouwehand, Willem H and Schunkert, Heribert and Thompson, John R and Spector, Tim D and Gieger, Christian and Trégouët, David-Alexandre and Deloukas, Panos and Samani, Nilesh J
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9933, pp. 1990 - 1998
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7. Full Text 157 Myeloid expression of trib1 regulates the polarisation state of tissue resident macrophages that has consequences on plasma lipid and metabolic homeostasis
by Johnston, Jessica M and Angyal, Adrienn and Hadadi, Eva and Hamby, Stephen E and Bauer, Robert and Ilyas, Zabran and Szili, Daniel and Ariaans, Markus and Wilson, Heather L and Krauss, Ronald M and Rader, Daniel J and Goodall, Alison H and Francis, Sheila E and Kiss-Toth, Endre
Heart (British Cardiac Society), ISSN 1355-6037, 06/2017, Volume 103, Issue Suppl 5, pp. A113 - A113
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8. Full Text Investigation of the Filamin A–Dependent Mechanisms of Tissue Factor Incorporation into Microvesicles
by Collier, Mary E. W and Ettelaie, Camille and Goult, Benjamin T and Maraveyas, Anthony and Goodall, Alison H
Thrombosis and haemostasis, ISSN 0340-6245, 2017, Volume 117, Issue 11, pp. 2034 - 2044
Coagulation and Fibrinolysis | Tissue Factor | Filamin A | Microvesicles | Protease-Activated Receptor 2 | Lipid Rafts | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology
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9. Full Text Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
by Tsaprouni, Loukia G and Yang, Tsun-Po and Bell, Jordana and Dick, Katherine J and Kanoni, Stavroula and Nisbet, James and Viñuela, Ana and Grundberg, Elin and Nelson, Christopher P and Meduri, Eshwar and Buil, Alfonso and Cambien, Francois and Hengstenberg, Christian and Erdmann, Jeanette and Schunkert, Heribert and Goodall, Alison H and Ouwehand, Willem H and Dermitzakis, Emmanouil and Spector, Tim D and Samani, Nilesh J and Deloukas, Panos
Epigenetics, ISSN 1559-2294, 10/2014, Volume 9, Issue 10, pp. 1382 - 1396
CHRND | epigenome-wide screen | smoking | DNA methylation | CPOX | gene network | rs2697768 | metQTLs | Gene network | Epigenome-wide screen | Smoking | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Smoking - adverse effects | Genome-Wide Association Study | Epigenesis, Genetic | Humans | Middle Aged | Linear Models | Male | DNA Methylation | Sequence Analysis, RNA | Aged, 80 and over | CpG Islands | Adult | Female | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Index Medicus
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10. Full Text A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways
by Jones, Chris I and Bray, Sarah and Garner, Stephen F and Stephens, Jonathan and De Bono, Bernard and Angenent, Will G. J and Bentley, David and Burns, Philippa and Coffey, Alison and Deloukas, Panos and Earthrowl, Mark and Farndale, Richard W and Hoylaerts, Marc F and Koch, Kerstin and Rankin, Angela and Rice, Catherine M and Rogers, Jane and Samani, Nilesh J and Steward, Michael and Walker, Adam and Watkins, Nicholas A and Akkerman, Jan-Willem and Dudbridge, Frank and Goodall, Alison H and Ouwehand, Willem H and Bloodomics Consortium
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 7, pp. 1405 - 1416
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Adenosine Diphosphate - genetics | P-Selectin - metabolism | Genomics | Humans | Quantitative Trait Loci - physiology | 3' Untranslated Regions - genetics | 3' Untranslated Regions - metabolism | Male | Blood Platelets - physiology | Inositol 1,4,5-Trisphosphate Receptors - biosynthesis | Cell Degranulation - genetics | Blood Platelets - cytology | Female | Collagen - genetics | Receptors, Cell Surface - biosynthesis | Europe | Gene Expression Regulation - physiology | European Continental Ancestry Group | Genotype | Signal Transduction - genetics | P-Selectin - genetics | Platelet Activation - genetics | Collagen - metabolism | Alleles | Polymorphism, Single Nucleotide | Adenosine Diphosphate - metabolism | Inositol 1,4,5-Trisphosphate Receptors - genetics | Receptors, Cell Surface - genetics | Index Medicus | Abridged Index Medicus
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11. Full Text Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages
by Christofidou, Paraskevi and Nelson, Christopher P and Nikpay, Majid and Qu, Liming and Li, Mingyao and Loley, Christina and Debiec, Radoslaw and Braund, Peter S and Denniff, Matthew and Charchar, Fadi J and Arjo, Ares Rocanin and Trégouët, David-Alexandre and Goodall, Alison H and Cambien, Francois and Ouwehand, Willem H and Roberts, Robert and Schunkert, Heribert and Hengstenberg, Christian and Reilly, Muredach P and Erdmann, Jeanette and McPherson, Ruth and König, Inke R and Thompson, John R and Samani, Nilesh J and Tomaszewski, Maciej
American journal of human genetics, ISSN 0002-9297, 08/2015, Volume 97, Issue 2, pp. 228 - 237
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Homozygote | European Continental Ancestry Group - genetics | Macrophages - metabolism | Age Factors | Gene Expression Regulation - genetics | Genes, Recessive - genetics | Humans | Coronary Artery Disease - genetics | Monocytes - metabolism | RNA, Messenger - metabolism | Genetic aspects | Homozygosity | Gene expression | Health aspects | Coronary heart disease | Risk factors | Genomics | Atherosclerosis | Cardiovascular disease | Genetics | Ribonucleic acid--RNA | Index Medicus
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12. Full Text Transcriptomic analysis of the ion channelome of human platelets and megakaryocytic cell lines
by Wright, Joy R and Amisten, Stefan and Goodall, Alison H and Mahaut-Smith, Martyn P
Thrombosis and haemostasis, ISSN 0340-6245, 03/2016, Volume 116, Issue 8, pp. 272 - 284
Cellular Haemostasis and Platelets | Receptors | Megakaryocytes | Molecular biology methods | Platelet physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Cell Line | Gene Expression | Humans | RNA, Messenger - genetics | Ion Channels - genetics | Gene Expression Profiling | Chloride Channels - genetics | Potassium Channels - genetics | Chloride Channels - blood | RNA, Messenger - blood | Blood Platelets - metabolism | Transient Receptor Potential Channels - genetics | Adult | Megakaryocytes - metabolism | Ion Channels - blood | Transient Receptor Potential Channels - blood | Potassium Channels - blood | megakaryocytes | receptors | molecular biology methods
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