X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (26) 26
animals (21) 21
index medicus (20) 20
biotechnology & applied microbiology (13) 13
pharmacology & pharmacy (12) 12
biomarkers (11) 11
united states (11) 11
genomics (9) 9
biological markers (8) 8
gene expression (8) 8
rats (8) 8
reproducibility of results (8) 8
toxicology (8) 8
biotechnology (7) 7
arrays (6) 6
cancer (6) 6
quality control (6) 6
research (6) 6
united states food and drug administration (6) 6
validation (6) 6
analysis (5) 5
biochemistry (5) 5
drug development (5) 5
gene expression profiling - methods (5) 5
pharmacogenetics (5) 5
rats, sprague-dawley (5) 5
toxicogenomics (5) 5
usage (5) 5
article (4) 4
biochemical research methods (4) 4
cells (4) 4
dna microarrays (4) 4
drug approval (4) 4
gene expression profiling (4) 4
gene expression profiling - standards (4) 4
kidney - pathology (4) 4
male (4) 4
medicine, research & experimental (4) 4
molecular biology (4) 4
oligonucleotide array sequence analysis - instrumentation (4) 4
oligonucleotide array sequence analysis - methods (4) 4
pathology (4) 4
performance (4) 4
pharmacogenomics (4) 4
sensitivity and specificity (4) 4
surrogate end-points (4) 4
biochemistry, general (3) 3
biology (3) 3
biomarker (3) 3
biomarkers - analysis (3) 3
biomedicine (3) 3
breast-cancer (3) 3
care and treatment (3) 3
chemistry (3) 3
computer science applications (3) 3
data submissions (3) 3
dna (3) 3
drug-related side effects and adverse reactions (3) 3
drugs (3) 3
europe (3) 3
gene-expression data (3) 3
genetic aspects (3) 3
genetic markers (3) 3
genetic research (3) 3
genetics (3) 3
genetics & heredity (3) 3
kidney - drug effects (3) 3
medicine (3) 3
messenger-rna (3) 3
microarray (3) 3
oligonucleotide array sequence analysis (3) 3
oligonucleotide array sequence analysis - standards (3) 3
pharmaceutical industry (3) 3
pharmacology/toxicology (3) 3
pharmacy (3) 3
platforms (3) 3
proceedings (3) 3
proteomics (3) 3
qrt-pcr (3) 3
quality assurance, health care - methods (3) 3
quantitative real-time pcr (3) 3
reverse transcriptase polymerase chain reaction (3) 3
rna, messenger - analysis (3) 3
algorithms (2) 2
aristolochic acid (2) 2
assay (2) 2
base sequence (2) 2
beer (2) 2
bioinformatics (2) 2
biomarkers - blood (2) 2
biomarkers - metabolism (2) 2
biomarkers of toxicity (2) 2
biomarkers, pharmacological (2) 2
biotechnology industry (2) 2
blood vessels - drug effects (2) 2
calibration (2) 2
case studies (2) 2
cdna arrays (2) 2
chromatography, high pressure liquid (2) 2
chronic diseases (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Clinical and Translational Science, ISSN 1752-8054, 09/2019, Volume 12, Issue 5, pp. 431 - 439
The evolution of chemistries and instrument platforms for next‐generation sequencing has led to sequencing of genomic variants in both tumor biopsies as well... 
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | CIRCULATING-TUMOR-CELLS | SURROGATE END-POINTS | BIOMARKER | DNA | METASTATIC BREAST-CANCER | PROGRESSION | Product development | Platforms | Regulatory agencies | Laboratories | Tumor cells | Decision making | Labyrinth | FDA approval | Organic chemistry | Biopsy | Risk levels | Biomarkers | Bioindicators | Diagnostic systems | Deoxyribonucleic acid--DNA | Tumors | Review
Journal Article
by Shi, Leming and Campbell, Gregory and Jones, Wendell D and Campagne, Fabien and Wen, Zhining and Walker, Stephen J and Su, Zhenqiang and Chu, Tzu-Ming and Goodsaid, Federico M and Pusztai, Lajos and Shaughnessy, John D and Oberthuer, André and Thomas, Russell S and Paules, Richard S and Fielden, Mark and Barlogie, Bart and Chen, Weijie and Du, Pan and Fischer, Matthias and Furlanello, Cesare and Gallas, Brandon D and Ge, Xijin and Megherbi, Dalila B and Symmans, W Fraser and Wang, May D and Zhang, John and Bitter, Hans and Brors, Benedikt and Bushel, Pierre R and Bylesjo, Max and Chen, Minjun and Cheng, Jie and Cheng, Jing and Chou, Jeff and Davison, Timothy S and Delorenzi, Mauro and Deng, Youping and Devanarayan, Viswanath and Dix, David J and Dopazo, Joaquin and Dorff, Kevin C and Elloumi, Fathi and Fan, Jianqing and Fan, Shicai and Fan, Xiaohui and Fang, Hong and Gonzaludo, Nina and Hess, Kenneth R and Hong, Huixiao and Huan, Jun and Irizarry, Rafael A and Judson, Richard and Juraeva, Dilafruz and Lababidi, Samir and Lambert, Christophe G and Li, Li and Li, Yanen and Li, Zhen and Lin, Simon M and Liu, Guozhen and Lobenhofer, Edward K and Luo, Jun and Luo, Wen and McCall, Matthew N and Nikolsky, Yuri and Pennello, Gene A and Perkins, Roger G and Philip, Reena and Popovici, Vlad and Price, Nathan D and Qian, Feng and Scherer, Andreas and Shi, Tieliu and Shi, Weiwei and Sung, Jaeyun and Thierry-Mieg, Danielle and Thierry-Mieg, Jean and Thodima, Venkata and Trygg, Johan and Vishnuvajjala, Lakshmi and Wang, Sue Jane and Wu, Jianping and Wu, Yichao and Xie, Qian and Yousef, Waleed A and Zhang, Liang and Zhang, Xuegong and Zhong, Sheng and Zhou, Yiming and Zhu, Sheng and Arasappan, Dhivya and Bao, Wenjun and Lucas, Anne Bergstrom and Berthold, Frank and Brennan, Richard J and Buness, Andreas and Catalano, Jennifer G and Chang, Chang and Chen, Rong and Cheng, Yiyu and ... and MAQC Consortium and Umeå universitet and Teknisk-naturvetenskapliga fakulteten and Kemiska institutionen
Nature Biotechnology, ISSN 1087-0156, 08/2010, Volume 28, Issue 8, pp. 827 - 838
Journal Article
Toxicology, ISSN 0300-483X, 2007, Volume 245, Issue 3, pp. 219 - 223
Abstract Biomarkers may be qualified using different qualification processes. A passive approach for qualification has been to accept the end of discussions in... 
Emergency | Consortia | Biomarkers | VALIDATION | PHARMACOLOGY & PHARMACY | SURROGATE END-POINTS | TOXICOLOGY | consortia | biomarkers | Reference Standards | Animals | Humans | Biomarkers - analysis
Journal Article
Science Translational Medicine, ISSN 1946-6234, 09/2010, Volume 2, Issue 47, pp. 47ps44 - 47ps44
The gap between development of exploratory biomarkers and their acceptance in drug development and regulatory review is a hurdle in the development of better... 
MEDICINE, RESEARCH & EXPERIMENTAL | TOXICITY | SAFETY BIOMARKERS | KIDNEY INJURY | CELL BIOLOGY | Biomarkers - metabolism | Animals | United States | Humans | Translational Medical Research | Drug Approval | United States Food and Drug Administration
Journal Article
by Shi, Leming and Reid, Laura H and Jones, Wendell D and Shippy, Richard and Warrington, Janet A and Baker, Shawn C and Collins, Patrick J and De Longueville, Francoise and Kawasaki, Ernest S and Lee, Kathleen Y and Luo, Yuling and Sun, Yongming Andrew and Willey, James C and Setterquist, Robert A and Fischer, Gavin M and Tong, Weida and Dragan, Yvonne P and Dix, David J and Frueh, Felix W and Goodsaid, Federico M and Herman, Damir and Jensen, Roderick V and Johnson, Charles D and Lobenhofer, Edward K and Puri, Raj K and Scherf, Uwe and Thierry-Mieg, Jean and Wang, Charles and Wilson, Mike and Wolber, Paul K and Zhang, Lu and Slikker, William and Amur, Shashi and Bao, Wenjun and Barbacioru, Catalin C and Lucas, Anne Bergstrom and Bertholet, Vincent and Boysen, Cecilie and Bromley, Bud and Brown, Donna and Brunner, Alan and Canales, Roger and Cao, Xiaoxi Megan and Cebula, Thomas A and Chen, James J and Cheng, Jing and Chu, Tzu-Ming and Chudin, Eugene and Corson, John and Corton, J Christopher and Croner, Lisa J and Davies, Christopher and Davison, Timothy S and Delenstarr, Glenda and Deng, Xutao and Dorris, David and Eklund, Aron C and Fan, Xiao-Hui and Fang, Hong and Fulmer-Smentek, Stephanie and Fuscoe, James C and Gallagher, Kathryn and Ge, Weigong and Guo, Lei and Guo, Xu and Hager, Janet and Haje, Paul K and Han, Jing and Han, Tao and Harbottle, Heather C and Harris, Stephen C and Hatchwell, Eli and Hauser, Craig A and Hester, Susan and Hong, Huixiao and Hurban, Patrick and Jackson, Scott A and Ji, Hanlee and Knight, Charles R and Kuo, Winston P and LeClerc, J. Eugene and Levy, Shawn and Li, Quan-Zhen and Liu, Chunmei and Liu, Ying and Lombardi, Michael J and Ma, Yunqing and Magnuson, Scott R and Maqsodi, Botoul and McDaniel, Tim and Mei, Nan and Myklebost, Ola and Ning, Baitang and Novoradovskaya, Natalia and Orr, Michael S and Osborn, Terry W and Papallo, Adam and Patterson, Tucker A and Perkins, Roger G and Peters, Elizabeth H and ... and MAQC Consortium
Nature Biotechnology, ISSN 1087-0156, 09/2006, Volume 24, Issue 9, pp. 1151 - 1161
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 08/2008, Volume 9, Issue 9, pp. S10 - S10
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 07/2005, Volume 6, Issue 2, pp. S12 - S12
Background: The acceptance of microarray technology in regulatory decision-making is being challenged by the existence of various platforms and data analysis... 
QA/QC | NEED | GENE-EXPRESSION MEASUREMENTS | PERSPECTIVE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | OLIGONUCLEOTIDE MICROARRAYS | PERFORMANCE | BIOCHEMICAL RESEARCH METHODS | NOISE | ARRAYS | Protein Array Analysis - standards | Databases, Genetic - standards
Journal Article
ENVIRONMENTAL HEALTH PERSPECTIVES, ISSN 0091-6765, 03/2004, Volume 112, Issue 4, pp. 456 - 459
Differences in hybridization platforms used in gene array analysis experiments can lead to significant differences in hybridization results. In this study we... 
ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | oligo arrays | cDNA arrays | toxicogenomics | quantitative real-time PCR | gene expression
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 02/2008, Volume 8, Issue 2, pp. 267 - 270
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2003, Volume 20, Issue 9, pp. 1373 - 1380
Journal Article