Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
microbiology (154) 154
biochemistry (153) 153
chemistry (153) 153
enzymology (153) 153
metallurgy (153) 153
beer (151) 151
mutation or genetic engineering (151) 151
spirits (151) 151
vinegar (151) 151
wine (151) 151
compositions thereof (137) 137
culture media (137) 137
microorganisms or enzymes (137) 137
propagating, preserving or maintaining microorganisms (137) 137
compositions or test papers therefor (53) 53
condition-responsive control in microbiological orenzymological processes (53) 53
measuring or testing processes involving enzymes, nucleicacids or microorganisms (53) 53
processes of preparing such compositions (53) 53
science & technology (41) 41
life sciences & biomedicine (24) 24
humans (19) 19
crispr (17) 17
multidisciplinary sciences (17) 17
science & technology - other topics (17) 17
crispr-cas systems (16) 16
biochemistry & molecular biology (15) 15
human necessities (13) 13
hygiene (13) 13
medical or veterinary science (13) 13
nucleic acids (13) 13
preparations for medical, dental, or toilet purposes (13) 13
enzymes (12) 12
ribonucleic acid--rna (12) 12
cell biology (11) 11
bacterial proteins - genetics (10) 10
genomes (10) 10
genomics (10) 10
deoxyribonucleic acid--dna (9) 9
hek293 cells (9) 9
rna (9) 9
bacterial proteins - chemistry (8) 8
investigating or analysing materials by determining theirchemical or physical properties (8) 8
measuring (8) 8
organic chemistry (8) 8
physics (8) 8
testing (8) 8
animals (7) 7
bacterial proteins - metabolism (7) 7
crispr-associated proteins - genetics (7) 7
endonucleases - chemistry (7) 7
endonucleases - genetics (7) 7
fermentation or enzyme-using processes to synthesise a desiredchemical compound or composition or to separate optical isomersfrom a racemic mixture (7) 7
methods (7) 7
rna, guide - genetics (7) 7
crispr-associated proteins - metabolism (6) 6
mice (6) 6
analysis (5) 5
base sequence (5) 5
biochemical research methods (5) 5
clustered regularly interspaced short palindromic repeats (5) 5
crispr-cas systems - genetics (5) 5
crystal structure (5) 5
derivatives thereof (5) 5
endonucleases - metabolism (5) 5
genetic engineering (5) 5
molecular sequence data (5) 5
nucleosides (5) 5
nucleotides (5) 5
sugars (5) 5
biotechnology & applied microbiology (4) 4
chemical or physical laboratory apparatus for general use (4) 4
crispr-associated proteins - chemistry (4) 4
crystallography, x-ray (4) 4
escherichia coli - genetics (4) 4
gene editing - methods (4) 4
gene expression (4) 4
genetic aspects (4) 4
genetic engineering - methods (4) 4
multiplexing (4) 4
mutation (4) 4
nucleases (4) 4
nucleotide sequence (4) 4
peptides (4) 4
performing operations (4) 4
physical or chemical processes or apparatus in general (4) 4
ribonuclease (4) 4
rna, viral - analysis (4) 4
sensitivity (4) 4
substrate specificity (4) 4
transporting (4) 4
bacteria (3) 3
biochemistry, genetics and molecular biology (3) 3
cell line, tumor (3) 3
dengue (3) 3
dengue virus - isolation & purification (3) 3
diagnostic systems (3) 3
editing (3) 3
gene library (3) 3
gene targeting - methods (3) 3
leptotrichia - genetics (3) 3
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (209) 209
French (75) 75
German (26) 26
Chinese (11) 11
Korean (11) 11
Danish (4) 4
Portuguese (3) 3
Spanish (2) 2
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text S15.2 Crispr diagnostics: expanding the nucleic acid detection toolbox by harnessing microbial diversity
by Gootenberg, Jonathan
Sexually transmitted infections, ISSN 1368-4973, 07/2019, Volume 95, Issue Suppl 1, p. A24
CRISPR | Enzymes | Deoxyribonucleic acid--DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Nucleic acid detection with CRISPR-Cas13a/C2c2
by Gootenberg, Jonathan S and Abudayyeh, Omar O and Lee, Jeong Wook and Essletzbichler, Patrick and Dy, Aaron J and Joung, Julia and Verdine, Vanessa and Donghia, Nina and Daringer, Nichole M and Freije, Catherine A and Myhrvold, Cameron and Bhattacharyya, Roby P and Livny, Jonathan and Regev, Aviv and Koonin, Eugene V and Hung, Deborah T and Sabeti, Pardis C and Collins, James J and Zhang, Feng
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2017, Volume 356, Issue 6336, pp. 438 - 442
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Circulating Tumor DNA - analysis | Zika Virus - genetics | Circulating Tumor DNA - genetics | Ribonucleases - chemistry | Humans | Bacterial Proteins - chemistry | RNA, Viral - analysis | RNA Cleavage | Zika Virus - isolation & purification | Dengue Virus - genetics | Bacteria - isolation & purification | RNA, Viral - genetics | Zika Virus Infection - diagnosis | Neoplasms - genetics | Point-of-Care Systems | Clustered Regularly Interspaced Short Palindromic Repeats | DNA, Bacterial - analysis | Bacteria - pathogenicity | Dengue Virus - isolation & purification | Mutation | Dengue - diagnosis | Methods | Nucleotide sequencing | DNA sequencing | Vector-borne diseases | Pathogens | CRISPR | Target recognition | Nucleotide sequence | Dengue | Viruses | Zika virus | Nucleic acids | Ribonuclease | Recombinase | Ribonucleic acid--RNA | Sensitivity | Genotyping | Reagents | Bacteria | Deoxyribonucleic acid--DNA | Index Medicus | Amplification | Ribonucleic acids | Deoxyribonucleic acid
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a and Csm6
by Gootenberg, Jonathan S and Abudayyeh, Omar O and Kellner, Max J and Joung, Julia and Collins, James J and Zhang, Feng
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2018, Volume 360, Issue 6387, pp. 439 - 444
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CRISPR-Associated Proteins - chemistry | RNA - analysis | DNA - analysis | Humans | Sensitivity and Specificity | Bacterial Proteins - chemistry | RNA, Viral - analysis | Dengue Virus - isolation & purification | Enzyme Assays | Zika Virus - isolation & purification | Endonucleases - chemistry | Multiplexing | Vector-borne diseases | CRISPR | Enzymes | RNA viruses | Single-stranded DNA | Dengue | Viral diseases | Viruses | Genomes | Nucleic acids | Ribonucleic acid--RNA | Sensitivity | Human papillomavirus | Sample preparation | Acids | Biopsy | Technology | Diagnostic systems | Mutation | Enzymology | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage
by Slaymaker, Ian M and Mesa, Pablo and Kellner, Max J and Kannan, Soumya and Brignole, Edward and Koob, Jeremy and Feliciano, Patricia R and Stella, Stefano and Abudayyeh, Omar O and Gootenberg, Jonathan S and Strecker, Jonathan and Montoya, Guillermo and Zhang, Feng
Cell reports (Cambridge), ISSN 2211-1247, 03/2019, Volume 26, Issue 13, pp. 3741 - 3751.e5
crystal structure | type VI CRISPR | Cas13b | CRISPR-Cas9 system | RNA-targeting | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Endonucleases - genetics | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Enzyme Stability | Substrate Specificity | Crystallography, X-Ray | Endonucleases - metabolism | RNA - chemistry | Endonucleases - chemistry | CRISPR-Cas Systems | Protein Binding | Protein Domains | Bacterial Proteins - metabolism | Prevotella - enzymology | RNA - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Field-deployable viral diagnostics using CRISPR-Cas13
by Myhrvold, Cameron and Freije, Catherine A and Gootenberg, Jonathan S and Abudayyeh, Omar O and Metsky, Hayden C and Durbin, Ann F and Kellner, Max J and Tan, Amanda L and Paul, Lauren M and Parham, Leda A and Garcia, Kimberly F and Barnes, Kayla G and Chak, Bridget and Mondini, Adriano and Nogueira, Mauricio L and Isern, Sharon and Michael, Scott F and Lorenzana, Ivette and Yozwiak, Nathan L and MacInnis, Bronwyn L and Bosch, Irene and Gehrke, Lee and Zhang, Feng and Sabeti, Pardis C
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2018, Volume 360, Issue 6387, pp. 444 - 448
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CRISPR-Associated Proteins - chemistry | Zika Virus - genetics | Humans | Bacterial Proteins - chemistry | Microcephaly - diagnosis | RNA, Viral - analysis | Enzyme Assays | Zika Virus - isolation & purification | Microcephaly - virology | Endonucleases - chemistry | Dengue Virus - genetics | Zika Virus Infection - diagnosis | Adaptation, Physiological - genetics | Dengue Virus - isolation & purification | Polymorphism, Single Nucleotide | Dengue - diagnosis | Enzymes | Usage | Dengue | Biochemical assays | Diagnosis | Single nucleotide polymorphisms | Health aspects | Methods | Vector-borne diseases | CRISPR | Pandemics | Single-stranded DNA | Viral diseases | Viruses | Genomes | Single-nucleotide polymorphism | Body fluids | Sensitivity | Human papillomavirus | Sample preparation | Infectious diseases | Acids | Technology | Diagnostic software | Serotypes | Diagnostic systems | Strains (organisms) | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text In vivo genome editing using Staphylococcus aureus Cas9
by Ran, F. Ann and Cong, Le and Yan, Winston X and Scott, David A and Gootenberg, Jonathan S and Kriz, Andrea J and Zetsche, Bernd and Shalem, Ophir and Wu, Xuebing and Makarova, Kira S and Koonin, Eugene V and Sharp, Phillip A and Zhang, Feng
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 186 - 191
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Staphylococcus aureus - enzymology | Cholesterol - blood | Genome - genetics | Substrate Specificity | Male | Proprotein Convertases - genetics | Proprotein Convertases - biosynthesis | Base Sequence | Serine Endopeptidases - genetics | Proprotein Convertases - blood | Genetic Engineering - methods | Staphylococcus aureus - genetics | Gene Targeting | Serine Endopeptidases - deficiency | Serine Endopeptidases - biosynthesis | CRISPR-Associated Proteins - genetics | Liver - metabolism | Mice, Inbred C57BL | Cholesterol - metabolism | Proprotein Convertases - deficiency | Animals | CRISPR-Associated Proteins - metabolism | Serine Endopeptidases - blood | Liver - physiology | Mice | Proprotein Convertase 9 | Enzymes | Usage | Genetic engineering | Genetic aspects | Methods | Staphylococcus aureus | Bacteria | Genomes | Biomedical research | Molecular weight | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
by Zetsche, Bernd and Gootenberg, Jonathan S and Abudayyeh, Omar O and Slaymaker, Ian M and Makarova, Kira S and Essletzbichler, Patrick and Volz, Sara E and Joung, Julia and van der Oost, John and Regev, Aviv and Koonin, Eugene V and Zhang, Feng
Cell (Cambridge), ISSN 0092-8674, 10/2015, Volume 163, Issue 3, pp. 759 - 771
Microbiological Laboratory | Microbiologie | VLAG | Microbiology | Laboratorium voor Microbiologie | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genetic Engineering - methods | Amino Acid Sequence | Endonucleases - genetics | RNA, Guide - genetics | Humans | Molecular Sequence Data | Endonucleases - chemistry | Sequence Alignment | Francisella - enzymology | CRISPR-Cas Systems | HEK293 Cells | Nucleic Acid Conformation | Francisella - genetics | Enzymes | Nucleases | RNA | Genomics | Cells | Research institutes | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text RNA editing with CRISPR-Cas13
by Cox, David B. T and Gootenberg, Jonathan S and Abudayyeh, Omar O and Franklin, Brian and Kellner, Max J and Joung, Julia and Zhang, Feng
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2017, Volume 358, Issue 6366, pp. 1019 - 1027
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biotechnology | Genetic Therapy | Endonucleases - genetics | Protein Engineering - methods | Adenosine Deaminase - genetics | Adenosine Deaminase - metabolism | RNA Editing | Humans | Bacterial Proteins - genetics | Endonucleases - metabolism | Recombinant Fusion Proteins - metabolism | Gene Knockdown Techniques | Endonucleases - classification | Diabetes Insipidus, Nephrogenic - therapy | Mutagenesis | Diabetes Insipidus, Nephrogenic - genetics | CRISPR-Cas Systems | HEK293 Cells | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | Bacterial Proteins - classification | Fanconi Anemia - genetics | Fanconi Anemia - therapy | RNA | CRISPR | Protein engineering | Adenosine | RNA editing | Genetic disorders | Editing | Adenosine deaminase | Ribonuclease | Nucleic acids | Mammals | Gene expression | Ribonucleic acid--RNA | Gene sequencing | Mammalian cells | Engineering | Mutation | Repair | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
by Konermann, Silvana and Brigham, Mark D and Trevino, Alexandro E and Joung, Julia and Abudayyeh, Omar O and Barcena, Clea and Hsu, Patrick D and Habib, Naomi and Gootenberg, Jonathan S and Nishimasu, Hiroshi and Nureki, Osamu and Zhang, Feng
Nature (London), ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 583 - 588
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Transcriptional Activation - genetics | Genetic Testing | RNA, Untranslated - metabolism | Humans | DNA, Complementary - genetics | Genetic Loci - genetics | RNA, Untranslated - genetics | Melanoma - genetics | DNA, Complementary - biosynthesis | Indoles - pharmacology | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Gene Expression Regulation, Neoplastic - genetics | Genetic Engineering - methods | Reproducibility of Results | Gene Library | CRISPR-Associated Proteins - genetics | Up-Regulation - genetics | Sulfonamides - pharmacology | CRISPR-Cas Systems - genetics | Genome, Human - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | RNA, Untranslated - biosynthesis | CRISPR-Associated Proteins - metabolism | Melanoma - drug therapy | Cell Line, Tumor | Drug Resistance, Neoplasm - drug effects | Enzymes | Nucleotide sequence | Genetic research | Genomes | Genetic aspects | Genetic engineering | Genetic transcription | Research | Proteins | Transcription factors | Genomics | Melanoma | Epigenetics | Drug resistance | Gene expression | Crystal structure | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights