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Lancet, The, ISSN 0140-6736, 2014, Volume 384, Issue 9944, pp. 665 - 673
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 10, pp. 1137 - 1146
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 2, pp. 141 - 151
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9807, pp. 1931 - 1939
Journal Article
Lancet, The, ISSN 0140-6736, 2007, Volume 370, Issue 9605, pp. 2103 - 2111
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 6, pp. 490 - 499
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2015, Volume 33, Issue 2, pp. 172 - 179
Purpose This open-label phase III trial evaluated efficacy and tolerability of linifanib versus sorafenib in patients with advanced hepatocellular carcinoma... 
ANGIOGENESIS | ONCOLOGY | PATHWAY | SUNITINIB | ABT-869 | RISK | BRIVANIB | INHIBITOR | CANCER | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Niacinamide - analogs & derivatives | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Hand-Foot Syndrome - etiology | Indazoles - administration & dosage | Protein Kinase Inhibitors - adverse effects | Liver Neoplasms - etiology | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - adverse effects | Phenylurea Compounds - adverse effects | Hypertension - chemically induced | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - etiology | Odds Ratio | Drug Administration Schedule | Risk Factors | Kaplan-Meier Estimate | Liver Neoplasms - drug therapy | Niacinamide - adverse effects | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Treatment Outcome | Niacinamide - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Phenylurea Compounds - administration & dosage | Protein Kinase Inhibitors - therapeutic use | Sorafenib | Carcinoma, Hepatocellular - pathology | Aged | Indazoles - adverse effects | Indazoles - therapeutic use | Bone3 | ORIGINAL REPORTS | Bios3
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2017, Volume 127, Issue 6, pp. 2392 - 2406
Quiescent and proliferating leukemia cells accumulate highly lethal DNA double-strand breaks that are repaired by 2 major mechanisms: BRCA-dependent homologous... 
GENOMIC INSTABILITY | MEDICINE, RESEARCH & EXPERIMENTAL | POLY(ADP-RIBOSE) POLYMERASE | NHEJ PATHWAYS | HEMATOPOIETIC STEM-CELLS | DOUBLE-STRAND BREAKS | PARP | HOMOLOGOUS RECOMBINATION | DNA-REPAIR | CANCER | CHRONIC MYELOID-LEUKEMIA | Cell Proliferation | Mouse Embryonic Stem Cells - physiology | Humans | Transcriptome | DNA Breaks, Double-Stranded | Genes, Lethal | DNA End-Joining Repair | Genes, BRCA2 | Antineoplastic Agents - pharmacology | Genes, BRCA1 | Leukemia - genetics | Cricetinae | Leukemia - drug therapy | Mice, SCID | Piperazines - pharmacology | Mice, Knockout | Xenograft Model Antitumor Assays | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Animals | Cell Transformation, Neoplastic | Genes, abl | Cell Line, Tumor | Mice, Inbred NOD | Mice | Biotechnology | Pharmacogenetics | Leukemia | Analysis | Genes | Genetic aspects | Genetic transcription | Protein kinases | Sugars | Monosaccharides | Cancer | Cell proliferation | Gene mutations | Cancer cells | Development and progression | Gene expression | Health aspects | BCR protein | Flow cytometry | DNA damage | Homologous recombination | Reverse transcription | Genomes | Lethality | Breast cancer | Drug delivery | Kinases | DNA repair | Polymerase chain reaction | Poly(ADP-ribose) Polymerase 1 | DNA-dependent protein kinase | DNA microarrays | Ribose | Stem cells | DNA methylation | Mutation | Solid tumors
Journal Article
Heart, ISSN 1355-6037, 02/2017, Volume 103, Issue 4, pp. 307 - 314
Journal Article