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by Walker, Gareth J and Harrison, James W and Heap, Graham A and Voskuil, Michiel D and Andersen, Vibeke and Anderson, Carl A and Ananthakrishnan, Ashwin N and Barrett, Jeffrey C and Beaugerie, Laurent and Bewshea, Claire M and Cole, Andy T and Cummings, Fraser R and Daly, Mark J and Ellul, Pierre and Fedorak, Richard N and Festen, Eleonora A. M and Florin, Timothy H and Gaya, Daniel R and Halfvarson, Jonas and Hart, Ailsa L and Heerasing, Neel M and Hendy, Peter and Irving, Peter and Jones, Samuel E and Koskela, Jukka and Lindsay, James O and Mansfield, John C and McGovern, Dermot and Parkes, Miles and Pollok, Richard C. G and Ramakrishnan, Subramaniam and Rampton, David S and Rivas, Manuel A and Russell, Richard K and Schultz, Michael and Sebastian, Shaji and Seksik, Philippe and Singh, Abhey and So, Kenji and Sokol, Harry and Subramaniam, Kavitha and Todd, Anthony and Annese, Vito and Weersma, Rinse K and Xavier, Ramnik and Ward, Rebecca and Weedon, Michael N and Goodhand, James R and Kennedy, Nicholas A and Ahmad, Tariq and Holden, Arthur L and Andrews, Jane and Auth, Marcus and Babu, Sathish and Bampton, Peter and Banim, Paul and Barnes, Theresa and Basude, Dharam and Beckly, John and Bell, Andy and Bell, Sally and Bhandari, Pradeep and Bloom, Stuart and Border, Dave and Bredin, Francesca and Brookes, Matthew J and Brown, Matthew and Calvert, Chris and Campbell, David and Chanchlani, Neil and Chaudhary, Basant and Chaudhary, Rakesh and Chung-Faye, Guy and Colleypriest, Ben and Connor, Susan and Cooney, Rachel and Cooper, Sheldon and Creed, Tom J and Croft, Nick and Cullen, Sue and D'Amato, Mauro and D'Inca, Renata and Dalal, Helen and Daneshmend, Tawfique K and Das, Debasish and Delaney, Michael and DeSilva, Shanika and Dhar, Anjan and Dharmasiri, Suranga and Direkze, Natalie and Dunckley, Paul and Elphick, David and Everett, Simon M and Feeney, Mark and Fell, John and Foley, Stephen and Franke, Andre and Gavin, Daniel and Gee, Ian and Ghosh, Deb and ... and IBD Pharmacogenetics Study Grp and IBD Pharmacogenetics Study Group and for the IBD Pharmacogenetics Study Group
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 02/2019, Volume 321, Issue 8, pp. 753 - 761
IMPORTANCE Use of thiopurines may be limited by myelosuppression. TPMT pharmacogenetic testing identifies only 25% of at-risk patients of European ancestry.... 
MEDICINE, GENERAL & INTERNAL | S-METHYLTRANSFERASE | POLYMORPHISMS | MANAGEMENT | PREDICTOR | THERAPY | ACUTE LYMPHOBLASTIC-LEUKEMIA | SUSCEPTIBILITY | AZATHIOPRINE | MERCAPTOPURINE INTOLERANCE | CHILDREN | Haplotypes | Crohn Disease - genetics | Genome-Wide Association Study | Colitis, Ulcerative - metabolism | Humans | Methyltransferases - metabolism | Colitis, Ulcerative - genetics | Methyltransferases - genetics | Pyrophosphatases - genetics | Crohn Disease - metabolism | European Continental Ancestry Group | Male | Case-Control Studies | Methyltransferases - therapeutic use | Exome | Young Adult | Crohn Disease - drug therapy | Adolescent | Adult | Female | Leukocyte Count | Polymorphism, Single Nucleotide | Colitis, Ulcerative - drug therapy | Sequence Analysis, DNA - methods | Antimitotic agents | Complications and side effects | Inflammatory bowel diseases | Genetic variation | Myelosuppression | Dosage and administration | Genetic aspects | Research | Antineoplastic agents | Drug therapy | Health aspects | Chromosome 6 | Risk | Genomes | Chromosome deletion | Pharmacology | Gene deletion | Disease control | Patients | Inflammatory bowel disease | White blood cells | Genetic variance | Genotyping | Clonal deletion | Intestine | Deletion | Chromosome 13 | Genetic testing | Genotypes | Index Medicus | Abridged Index Medicus | Original Investigation
Journal Article
Ophthalmology, ISSN 0161-6420, 07/2019, Volume 126, Issue 7, pp. 935 - 945
We set out to describe the natural history of keratoconus. We included untreated patients, and our key outcome measures were vision, refraction, and corneal... 
Journal Article
Cornea, ISSN 0277-3740, 06/2019, p. 1
PURPOSE:To present a case series of patients with corneal and scleral changes associated with the use of skin-lightening creams. This is the first report of... 
Journal Article
Ophthalmology, ISSN 0161-6420, 2015, Volume 122, Issue 2, pp. 391 - 398.e5
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2015, Volume 33, Issue 4, pp. 332 - 339
Journal Article