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The Lancet, ISSN 0140-6736, 01/2018, Volume 391, Issue 10118, pp. 319 - 328
Canakinumab, a monoclonal antibody targeting interleukin-1β, reduces inflammation and cardiovascular event rates with no effect on lipid concentrations.... 
MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | LDL-CHOLESTEROL | EFFICACY | STATIN THERAPY | INFLAMMATION | ATHEROSCLEROSIS | PREVENTION | ACUTE CORONARY SYNDROMES | OUTCOMES | ARTERY-DISEASE | Reduction | C-reactive protein | Mortality | Cardiovascular disease | Secondary analysis | Health risk assessment | Low density lipoprotein | Statins
Journal Article
by Ridker, Paul and Ridker, Paul M and MacFadyen, Jean G and Thuren, Tom and Everett, Brendan and Everett, Brendan M and Libby, Peter and Glynn, Robert J and Glynn, Robert and Lorenzatti, Alberto and Krum, Henry and Varigos, John and Siostrzonek, Peter and Sinnaeve, Peter and Fonseca, Francisco and Nicolau, Jose and Gotcheva, Nina and Genest, Jacques and Yong, Huo and Urina-Triana, Miguel and Milicic, Davor and Cifkova, Renata and Vettus, Riina and Koenig, Wolfgang and Anker, Stephan D and Manolis, Athanasios J and Wyss, Fernando and Forster, Tamas and Sigurdsson, Axel and Pais, Prem and Fucili, Alessandro and Ogawa, Hisao and Shimokawa, Hiroaki and Veze, Irina and Petrauskiene, Birute and Salvador, Leon and Kastelein, John and Cornel, Jan Hein and Klemsdal, Tor Ole and Medina, Felix and Budaj, Andrzej and Vida-Simiti, Luminita and Kobalava, Zhanna and Otasevic, Petar and Pella, Daniel and Lainscak, Mitja and Seung, Ki-Bae and Commerford, Patrick and Dellborg, Mikael and Donath, Marc and Hwang, Juey-Jen and Kultursay, Hakan and Flather, Marcus and Ballantyne, Christie and Bilazarian, Seth and Chang, William and East, Cara and Forgosh, Les and Harris, Barry and Ligueros, Monica and Bohula, Erin and Charmarthi, Bindu and Cheng, Susan and Chou, Sherry and Danik, Jacqueline and McMahon, Graham and Maron, Bradley and Ning, MingMing and Olenchock, Benjamin and Pande, Reena and Perlstein, Todd and Pradhan, Aruna and Rost, Natalia and Singhal, Aneesh and Taqueti, Viviany and Wei, Nancy and Burris, Howard and Cioffi, Angela and Dalseg, Anne Marie and Ghosh, Nilanjan and Gralow, Julie and Mayer, Tina and Rugo, Hope and Fowler, Vance and Limaye, Ajit P and Cosgrove, Sara and Levine, Donald and Lopes, Renato and Scott, John and Hilkert, Robert and Tamesby, Georgia and Mickel, Carolyn and Manning, Brian and Woelcke, Julian and Tan, Monique and Manfreda, Sheryl and Ponce, Tom and Kam, Jane and Saini, Ravinder and Banker, Kehur and ... and CANTOS Trial Grp and CANTOS Trial Group
The Lancet, ISSN 0140-6736, 10/2017, Volume 390, Issue 10105, pp. 1833 - 1842
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 18, pp. B157 - B157
  Background The aim of our study was to evaluate the diagnostic role of neutrophil gelatinase-associated lipocalin (NGAL) for early evaluation of kidney... 
Cardiovascular | Internal Medicine | Medical colleges | Angiography | Analysis | Cardiac patients | Cardiovascular disease | Medical imaging | Kidney diseases | Neutrophils
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Klinisk medicin | Clinical Medicine
Journal Article
European Journal of Preventive Cardiology, ISSN 2047-4873, 4/2016, Volume 23, Issue 6, pp. 636 - 648
Journal Article