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1. Full Text To INFINITY and Beyond: What Have We Learned and What Is Still Unknown About Blood Pressure Lowering and Cognition?
by Gottesman, Rebecca F
Circulation, ISSN 0009-7322, 11/2019, Volume 140, Issue 20, pp. 1636 - 1638
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2. Full Text Survivor’s Remorse
: Is There an Increased Risk of Dementia After Surviving a Myocardial Infarction?
by Gottesman, Rebecca F
Circulation, ISSN 0009-7322, 02/2018, Volume 137, Issue 6, pp. 578 - 580
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3. Full Text Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene ( ) lower plasma low-density lipoprotein cholesterol... 
DENSITY-LIPOPROTEIN CHOLESTEROL | FACTOR ACETYLHYDROLASES | PROTEIN | LDL | GENETICS & HEREDITY | PCSK9 | PLATELET-ACTIVATING-FACTOR | TRAITS | Genetic Code | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Male | Genetic Variation | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Adult | Cholesterol, LDL - blood | Female | Subtilisins - metabolism | African Continental Ancestry Group - genetics | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Association Studies | Gene Frequency | Mice, Inbred C57BL | Linear Models | Cholesterol, HDL - genetics | Sequence Analysis, DNA | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Cholesterol, LDL - genetics | Phenotype | Animals | Coronary Disease - genetics | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Subtilisins - genetics | Aged | Mice | Cohort Studies | Genetic code | Genetic variation | Physiological aspects | Genetic research | Genetic aspects | Research | Coronary heart disease | Population genetics | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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4. Full Text Neurovascular and Cognitive Dysfunction in Hypertension
by Iadecola, Costantino and Gottesman, Rebecca F
Circulation research, 03/2019, Volume 124, Issue 7, pp. 1025 - 1044
Hypertension has emerged as a leading cause of age-related cognitive impairment. Long known to be associated with dementia caused by vascular factors,... 
brain blood supply | dementia | risk factors | Alzheimer’s disease | white matter pathology | biomarkers
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5. Full Text Predictors and assessment of cognitive dysfunction resulting from ischaemic stroke
by Gottesman, Rebecca F, MD and Hillis, Argye E, Prof
Lancet Neurology, The, ISSN 1474-4422, 2010, Volume 9, Issue 9, pp. 895 - 905
Summary Stroke remains a primary cause of morbidity throughout the world mainly because of its effect on cognition. Individuals can recover from physical... 
Neurology | ALZHEIMER-DISEASE | SMALL VESSEL DISEASE | POSITRON-EMISSION-TOMOGRAPHY | TRANSCRANIAL MAGNETIC STIMULATION | TISSUE-PLASMINOGEN ACTIVATOR | RIGHT HEMISPHERIC STROKE | CEREBRAL INFARCTIONS | UNILATERAL NEGLECT | WHITE-MATTER HYPERINTENSITIES | CORTICAL HYPOPERFUSION | CLINICAL NEUROLOGY | Neuropsychological Tests | Cognition Disorders - diagnosis | Predictive Value of Tests | Cognition Disorders - etiology | Humans | Magnetic Resonance Imaging - methods | Stroke - complications | Stroke (Disease) | Development and progression | Ischemia | Magnetization | Dementia | Cerebral infarction | Stroke | Neural networks | Cognitive ability | Dementia disorders | Cerebrovascular diseases | Injuries | Morbidity | Risk factors
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6. Full Text Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
by Lange, Leslie A and Lange, Ethan M and Lange, Christoph and Hu, Youna and Zhang, Qunyuan and Zhang, Ji and Zhang, He and Xue, Chenyi and Schmidt, Ellen M and Tang, Hua and Tang, Zheng-Zheng and Bizon, Chris and Smith, Nicholas L and Smith, Joshua D and Smith, Albert V and Turner, Emily H and Jun, Goo and Kang, Hyun Min and Peloso, Gina and Auer, Paul L and Auer, Paul and Li, Kuo-ping and Li, Mingyao and Li, Yun and Li, Bingshan and Li, Dalin and Flannick, Jason and Fuchsberger, Christian and Gaulton, Kyle and Lindgren, Cecilia and Locke, Adam and Manning, Alisa and Sim, Xueling and Rivas, Manuel A and Holmen, Oddgeir L and Gottesman, Omri and Lu, Yingchang and Ruderfer, Douglas and Stahl, Eli A and Duan, Qing and Durda, Peter and Durda, J. Peter and Jiao, Shuo and Isaacs, Aaron and Hofman, Albert and Bis, Joshua C and Bis, Joshua and Correa, Adolfo and Griswold, Michael E and Jakobsdottir, Johanna and Schreiner, Pamela and Schreiner, Pamela J and Feitosa, Mary F and Huffman, Jennifer E and Crosby, Jacy and Wassel, Chrstina L and Wassel, Christina L and Do, Ron and Franceschini, Nora and Martin, Lisa and Martin, Lisa W and Martin, Thomas R and Robinson, Jennifer G and Assimes, Themistocles L and Crosslin, David R and Rosenthal, Elisabeth A and Tsai, Michael Y and Tsai, Michael and Rieder, Mark J and Farlow, Deborah N and Folsom, Aaron R and Lumley, Thomas and Fox, Ervin R and Fox, Caroline S and Fox, P. Keolu and Fox, Ervin and Carlson, Christopher S and Peters, Ulrike and Jackson, Rebecca D and Jackson, Rebecca and van Duijn, Cornelia M and Uitterlinden, André G and Levy, Daniel and Rotter, Jerome I and Taylor, Herman A and Taylor, Kira C and Taylor, Kent and Gudnason, Vilmundur and Siscovick, David S and Fornage, Myriam and Borecki, Ingrid B and Hayward, Caroline and Rudan, Igor and Chen, Wei-Min and Chen, Y. Eugene and Chen, Donna T and Chen, Ida Y and Bottinger, Erwin P and Loos, Ruth J.F and Sætrom, Pål and ... and NHLBI Grand Opportunity Exome Sequ and NHLBI Grand Opportunity Exome Sequencing Project and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 233 - 245
Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs)... 
OBJECTIVES | HEART-DISEASE | PLASMA | GENE | SUSCEPTIBILITY | GENETICS & HEREDITY | DENSITY-LIPOPROTEIN-CHOLESTEROL | Dyslipidemias - genetics | Genetic Code | Follow-Up Studies | Humans | Middle Aged | Male | Proprotein Convertases - genetics | Exome | Dyslipidemias - blood | Serine Endopeptidases - genetics | Adult | Female | Receptors, LDL - genetics | Genome-Wide Association Study | Gene Frequency | Genotype | Sequence Analysis, DNA | Cholesterol, LDL - genetics | Phenotype | Apolipoproteins E - blood | Apolipoproteins E - genetics | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Lipase - genetics | Proprotein Convertase 9 | Genetic code | Genetic variation | Physiological aspects | Genetic research | Cholesterol, LDL | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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7. Full Text Cerebrovascular alterations in Alzheimer’s disease: incidental or pathogenic?
by Iadecola, Costantino and Gottesman, Rebecca F
Circulation research, ISSN 0009-7330, 8/2018, Volume 123, Issue 4, pp. 406 - 408
Alzheimer’s disease, the leading cause of cognitive impairment in the elderly, has traditionally been considered a disease of neurons. Structural and function... 
vascular cognitive impairment | vascular risk factors | Dementia
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8. Full Text Variability in Palliative Care Use after Intracerebral Hemorrhage at US Hospitals: A Multilevel Analysis
by Faigle, Roland and Gottesman, Rebecca F
Neuroepidemiology, ISSN 0251-5350, 08/2019, Volume 53, Issue 1-2, pp. 84 - 92
Background: Palliative care (PC) is an essential component of comprehensive care of patients with intracerebral hemorrhage (ICH). In the present study, we... 
Original Paper
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9. Full Text Stroke Incidence and Mortality Trends in US Communities, 1987 to 2011
by Koton, Silvia and Schneider, Andrea L. C and Rosamond, Wayne D and Shahar, Eyal and Sang, Yingying and Gottesman, Rebecca F and Coresh, Josef
JAMA, ISSN 0098-7484, 07/2014, Volume 312, Issue 3, pp. 259 - 268
IMPORTANCE: Prior studies have shown decreases in stroke mortality over time, but data on validated stroke incidence and long-term trends by race are limited.... 
INCIDENCE RATES | POPULATION | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | CARDIOVASCULAR-DISEASE | IMPROVED SURVIVAL | TEMPORAL TRENDS | ISCHEMIC-STROKE | ASSOCIATION | ATHEROSCLEROSIS RISK | SEVERITY | Brain Ischemia - complications | United States - epidemiology | Cerebral Hemorrhage - ethnology | Humans | Middle Aged | Risk Factors | Cerebral Hemorrhage - mortality | Hospitalization - statistics & numerical data | European Continental Ancestry Group - statistics & numerical data | Male | Mortality - trends | Incidence | African Continental Ancestry Group - statistics & numerical data | Sex Factors | Cardiovascular Diseases - epidemiology | Stroke - ethnology | Female | Aged | Brain Ischemia - mortality | Stroke - mortality | Brain Ischemia - ethnology | Cohort Studies | Stroke (Disease) | Complications and side effects | Care and treatment | United States | Mortality | Risk factors | African Americans | Stroke | Whites | Clinical outcomes
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10. Full Text Cognitive and Neurologic Outcomes after Coronary-Artery Bypass Surgery
by Selnes, Ola A and Gottesman, Rebecca F and Grega, Maura A and Baumgartner, William A and Zeger, Scott L and McKhann, Guy M
The New England Journal of Medicine, ISSN 0028-4793, 01/2012, Volume 366, Issue 3, pp. 250 - 257
For patients undergoing coronary-artery bypass grafting (CABG), adverse neurologic outcomes, including stroke and cognitive decline, are major concerns. Even... 
Neuropsychological Tests | Cognition Disorders - diagnosis | Stroke - etiology | Stroke - prevention & control | Cognition Disorders - etiology | Humans | Coronary Artery Bypass | Monitoring, Intraoperative | Stroke - physiopathology | Postoperative Complications - diagnosis | Incidence | Prevention | Complications and side effects | Treatment outcome | Evaluation | Nervous system diseases | Coronary artery bypass | Complications | Surgery | Causes of | Cognition disorders | Hypertension | Nuclear magnetic resonance--NMR | Older people | Mortality | Cognitive ability | Coronary artery | Patients
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11. Full Text Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
by Malik, Rainer and Chauhan, Ganesh and Traylor, Matthew and Sargurupremraj, Muralidharan and Okada, Yukinori and Mishra, Aniket and Rutten-Jacobs, Loes and Giese, Anne-Katrin and Van Der Laan, Sander W and Gretarsdottir, Solveig and Anderson, Christopher D and Chong, Michael and Adams, Hieab H. H and Ago, Tetsuro and Almgren, Peter and Amouyel, Philippe and Ay, Hakan and Bartz, Traci M and Benavente, Oscar R and Bevan, Steve and Boncoraglio, Giorgio B and Brown, Robert D and Butterworth, Adam S and Carrera, Caty and Carty, Cara L and Chasman, Daniel I and Chen, Wei-Min and Cole, John W and Correa, Adolfo and Cotlarciuc, Ioana and Cruchaga, Carlos and Danesh, John and De Bakker, Paul I. W and Destefano, Anita L and Den Hoed, Marcel and Duan, Qing and Engelter, Stefan T and Falcone, Guido J and Gottesman, Rebecca F and Grewal, Raji P and Gudnason, Vilmundur and Gustafsson, Stefan and Haessler, Jeffrey and Harris, Tamara B and Hassan, Ahamad and Havulinna, Aki S and Heckbert, Susan R and Holliday, Elizabeth G and Howard, George and Hsu, Fang-Chi and Hyacinth, Hyacinth I and Ikram, M. Arfan and Ingelsson, Erik and Irvin, Marguerite R and Jian, Xueqiu and Jiménez-Conde, Jordi and Johnson, Julie A and Jukema, J. Wouter and Kanai, Masahiro and Keene, Keith L and Kissela, Brett M and Kleindorfer, Dawn O and Kooperberg, Charles and Kubo, Michiaki and Lange, Leslie A and Langefeld, Carl D and Langenberg, Claudia and Launer, Lenore J and Lee, Jin-Moo and Lemmens, Robin and Leys, Didier and Lewis, Cathryn M and Lin, Wei-Yu and Lindgren, Arne G and Lorentzen, Erik and Magnusson, Patrik K and Maguire, Jane and Manichaikul, Ani and McArdle, Patrick F and Meschia, James F and Mitchell, Braxton D and Mosley, Thomas H and Nalls, Michael A and Ninomiya, Toshiharu and O'Donnell, Martin J and Psaty, Bruce M and Pulit, Sara L and Rannikmäe, Kristiina and Reiner, Alexander P and Rexrode, Kathryn M and Rice, Kenneth and Rich, Stephen S and Ridker, Paul M and Rost, Natalia S and Rothwell, Peter M and Rotter, Jerome I and Rundek, Tatjana and Sacco, Ralph L and Sakaue, Saori and Sale, Michele M and ... and AFGen Consortium and UK Young Lacunar DNA Study and EPIC-CVD Consortium and Int Stroke Genetics Consortium ISG and INVENT Consortium and Int Genomics Blood Pressure iGEN and MEGASTROKE Consortium and COMPASS Consortium and METASTROKE Consortium and EPIC-InterAct Consortium and Cohorts Heart Aging Res Genomic and BioBank Japan Cooperative Hosp Grp and NINDS Stroke Genetics Network Si and STARNET and Neurology Working Grp Charge Con and Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and International Stroke Genetics Consortium (ISGC) and NINDS Stroke Genetics Network (SiGN) and International Genomics of Blood Pressure (iGEN-BP) Consortium and BioBank Japan Cooperative Hospital Group and Neurology Working Group of the CHARGE Consortium and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik och genomik and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 524 - 537
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conducted a multiancestry genome-wide-association meta-analysis... 
GENETIC-VARIATION | RARE VARIANTS | HTRA1 MUTATIONS | CANDIDATE GENES | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | WHITE-MATTER HYPERINTENSITIES | ISCHEMIC-STROKE | COMPLEX TRAITS | BLOOD-PRESSURE | ATRIAL-FIBRILLATION | Stroke | Genes | Health risks | Risk | Cardiovascular disease | Genomes | Genetic diversity | Regression analysis | Loci | Meta-analysis | Consortia | Pleiotropy | Etiology | Blood pressure | Thromboembolism | Bioinformatics | Asians | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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