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1. Full Text TMOD-16. A NOVEL ALGORITHM FOR MANAGEMENT OF PEDIATRIC CRANIOPHARYNGIOMA
by Fouda, Mohammed and Zurakowski, David and Goumnerova, Liliana
Neuro-Oncology, ISSN 1522-8517, 04/2019, Volume 21, Issue Supplement_2, pp. ii124 - ii124
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2. Full Text Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
by Yoon-Jae Cho and Aviad Tsherniak and Pablo Tamayo and Sandro Santagata and Azra Ligon and Heidi Greulich and Rameen Berhoukim and Vladimir Amani and Liliana Goumnerova and Charles G. Eberhart and Ching C. Lau and James M. Olson and Richard J. Gilbertson and Amar Gajjar and Olivier Delattre and Marcel Kool and Keith Ligon and Matthew Meyerson and Jill P. Mesirov and Scott L. Pomeroy
Journal of Clinical Oncology, ISSN 0732-183X, 04/2011, Volume 29, Issue 11, pp. 1424 - 1430
Purpose Medulloblastomas are heterogeneous tumors that collectively represent the most common malignant brain tumor in children. To understand the molecular... 
CELLS | COPY NUMBER ABNORMALITIES | ONCOLOGY | PATHWAY | BETA-CATENIN STATUS | GENE-EXPRESSION | CENTRAL-NERVOUS-SYSTEM | HYBRIDIZATION | EXPRESSION PROFILES | HUMAN CANCERS | PEDIATRIC MEDULLOBLASTOMAS | Immunohistochemistry | Predictive Value of Tests | Prognosis | Genomics | Humans | Gene Expression Regulation, Neoplastic | In Situ Hybridization, Fluorescence | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Algorithms | Medulloblastoma - pathology | RNA, Neoplasm - genetics | Polymorphism, Single Nucleotide | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Child | Index Medicus | To4 | Original Reports | Pedi4 | Neur8 | Neur1
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3. Full Text Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
by Fontebasso, Adam M and Papillon-Cavanagh, Simon and Schwartzentruber, Jeremy and Nikbakht, Hamid and Gerges, Noha and Fiset, Pierre-Olivier and Bechet, Denise and Faury, Damien and De Jay, Nicolas and Ramkissoon, Lori A and Corcoran, Aoife and Jones, David T. W and Sturm, Dominik and Johann, Pascal and Tomita, Tadanori and Goldman, Stewart and Nagib, Mahmoud and Bendel, Anne and Goumnerova, Liliana and Bowers, Daniel C and Leonard, Jeffrey R and Rubin, Joshua B and Alden, Tord and Browd, Samuel and Geyer, J Russell and Leary, Sarah and Jallo, George and Cohen, Kenneth and Gupta, Nalin and Prados, Michael D and Carret, Anne-Sophie and Ellezam, Benjamin and Crevier, Louis and Klekner, Almos and Bognar, Laszlo and Hauser, Peter and Garami, Miklos and Myseros, John and Dong, Zhifeng and Siegel, Peter M and Malkin, Hayley and Ligon, Azra H and Albrecht, Steffen and Pfister, Stefan M and Ligon, Keith L and Majewski, Jacek and Jabado, Nada and Kieran, Mark W
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 5, pp. 462 - 466
Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor mutations encoding p.Lys27Met in... 
GLIOBLASTOMA | I RECEPTOR | GENES | MOUSE | GENETICS & HEREDITY | INTRINSIC PONTINE GLIOMAS | BMP RECEPTOR | HISTONE H3.3 | SUBGROUPS | ALK2 | FIBRODYSPLASIA OSSIFICANS PROGRESSIVA | Astrocytoma - genetics | Immunohistochemistry | Humans | Brain Neoplasms - genetics | Molecular Sequence Data | In Situ Hybridization, Fluorescence | DNA Copy Number Variations - genetics | DNA Methylation - genetics | Mutation - genetics | Activin Receptors, Type I - genetics | Sequence Analysis, DNA | Genome, Human - genetics | Bone Morphogenetic Proteins - metabolism | Animals | Base Sequence | Child | Smad Proteins - metabolism | Gene Expression Regulation, Neoplastic - genetics | Cell receptors | Gene mutations | Activins | Genetic aspects | Health aspects | Astrocytoma | Cancer in children | DNA methylation | Medical research | Mutation | Kinases | Index Medicus
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4. Full Text 352 Management Strategies for Hydrocephalus in Pediatric Posterior Fossa Brain Tumor
by Elkatatny, Amr M and Zurakowski, David and Goumnerova, Liliana
Neurosurgery, ISSN 0148-396X, 09/2018, Volume 65, Issue CN_suppl_1 Suppl 1, pp. 140 - 140
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5. Full Text Long‐term outcome of 4,040 children diagnosed with pediatric low‐grade gliomas: An analysis of the Surveillance Epidemiology and End Results (SEER) database
by Bandopadhayay, Pratiti and Bergthold, Guillaume and London, Wendy B and Goumnerova, Liliana C and Morales La Madrid, Andres and Marcus, Karen J and Guo, Dongjing and Ullrich, Nicole J and Robison, Nathan J and Chi, Susan N and Beroukhim, Rameen and Kieran, Mark W and Manley, Peter E
Pediatric Blood & Cancer, ISSN 1545-5009, 07/2014, Volume 61, Issue 7, pp. 1173 - 1179
Children with pediatric low-grade gliomas (PLGG) are known to have excellent 10-year survival rates; however the outcomes of adult survivors of PLGG are... 
SEER | outcome | pediatric low‐grade glioma | Pediatric low-grade glioma | Outcome | Glioma - mortality | Follow-Up Studies | Glioma - diagnosis | Humans | Risk Factors | Child, Preschool | Infant | Male | Survival Rate | Incidence | Disease-Free Survival | Adolescent | Adult | Female | Retrospective Studies | Child | Index Medicus | s | pediatric low-grade glioma
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6. Full Text Correction to: Iatrogenic obstructive hydrocephalus resulting from Gelfoam accumulation within the cerebral aqueduct: a case report
by Hazama, Ali and Driver, Joseph and Grannan, Benjamin and Dasenbrock, Hurmozdiyar and Goumnerova, Liliana
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, ISSN 0256-7040, 06/2019, Volume 35, Issue 6, pp. 1089 - 1089
The original version of this article unfortunately contained an error. The authors apologize to have miss looked a typo of author name "Joseph Diver". The... 
Medical colleges | Nervous system | Medical errors | Surgery
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7. Full Text MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
by Bandopadhayay, Pratiti and Ramkissoon, Lori A and Jain, Payal and Bergthold, Guillaume and Wala, Jeremiah and Zeid, Rhamy and Schumacher, Steven E and Urbanski, Laura and O'Rourke, Ryan and Gibson, William J and Pelton, Kristine and Ramkissoon, Shakti H and Han, Harry J and Zhu, Yuankun and Choudhari, Namrata and Silva, Amanda and Boucher, Katie and Henn, Rosemary E and Kang, Yun Jee and Knoff, David and Paolella, Brenton R and Gladden-Young, Adrianne and Varlet, Pascale and Pages, Melanie and Horowitz, Peleg M and Federation, Alexander and Malkin, Hayley and Tracy, Adam A and Seepo, Sara and Ducar, Matthew and Van Hummelen, Paul and Santi, Mariarita and Buccoliero, Anna Maria and Scagnet, Mirko and Bowers, Daniel C and Giannini, Caterina and Puget, Stephanie and Hawkins, Cynthia and Tabori, Uri and Klekner, Almos and Bognar, Laszlo and Burger, Peter C and Eberhart, Charles and Rodriguez, Fausto J and Hill, D. Ashley and Mueller, Sabine and Haas-Kogan, Daphne A and Phillips, Joanna J and Santagata, Sandro and Stiles, Charles D and Bradner, James E and Jabado, Nada and Goren, Alon and Grill, Jacques and Ligon, Azra H and Goumnerova, Liliana and Waanders, Angela J and Storm, Phillip B and Kieran, Mark W and Ligon, Keith L and Beroukhim, Rameen and Resnick, Adam C
Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 3, pp. 273 - 282
Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent genetic drivers. We performed genomic analysis of new and published data... 
TRANSFORMATION | PROTEIN | GENE | GENETICS & HEREDITY | C-MYB | ADENOID CYSTIC CARCINOMA | NEURAL STEM-CELL | BET BROMODOMAIN INHIBITION | CANCER | LOW-GRADE GLIOMAS | V-MYB | RNA-Binding Proteins - genetics | Humans | Oncogene Proteins, Fusion - biosynthesis | Carcinogenesis - genetics | Gene Expression Regulation, Neoplastic | Glioma - genetics | RNA-Binding Proteins - biosynthesis | Exome - genetics | Comparative Genomic Hybridization | Oncogene Proteins, Fusion - genetics | Gene Rearrangement | Glioma - pathology | Oncogene Proteins v-myb - biosynthesis | Cell Line, Tumor | Oncogene Proteins v-myb - genetics | High-Throughput Nucleotide Sequencing | Mutation | Child | Epigenetic inheritance | Gliomas | Genetic research | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Gene expression | Health aspects | Proteins | Pediatrics | Medical research | Transcription factors | Brain research | Brain cancer | Genomes | Kinases | Tumors | Cancer | Index Medicus
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8. Full Text NS-26THE ROLE OF SURGERY IN NON-NF-ASSOCIATED PEDIATRIC OPTIC PATHWAY GLIOMAS (OPG) - IS THERE A NEW PARADIGM?
by Lohkamp, Laura-Nanna and Manley, Peter and Kieran, Mark W and Ullrich, Nicole and Goumnerova, Liliana C
Neuro-Oncology, ISSN 1522-8517, 06/2016, Volume 18, Issue suppl 3, pp. iii132.4 - iii132
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9. Full Text Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
by Filbin, Mariella G and Tirosh, Itay and Hovestadt, Volker and Shaw, McKenzie L and Escalante, Leah E and Mathewson, Nathan D and Neftel, Cyril and Frank, Nelli and Pelton, Kristine and Hebert, Christine M and Haberler, Christine and Yizhak, Keren and Gojo, Johannes and Egervari, Kristof and Mount, Christopher and Van Galen, Peter and Bonal, Dennis M and Nguyen, Quang-De and Beck, Alexander and Sinai, Claire and Czech, Thomas and Dorfer, Christian and Goumnerova, Liliana and Lavarino, Cinzia and Carcaboso, Angel M and Mora, Jaume and Mylvaganam, Ravindra and Luo, Christina C and Peyrl, Andreas and Popović, Mara and Azizi, Amedeo and Batchelor, Tracy T and Frosch, Matthew P and Martinez-Lage, Maria and Kieran, Mark W and Bandopadhayay, Pratiti and Beroukhim, Rameen and Fritsch, Gerhard and Getz, Gad and Rozenblatt-Rosen, Orit and Wucherpfennig, Kai W and Louis, David N and Monje, Michelle and Slavc, Irene and Ligon, Keith L and Golub, Todd R and Regev, Aviv and Bernstein, Bradley E and Suvà, Mario L
Science, ISSN 0036-8075, 04/2018, Volume 360, Issue 6386, pp. 331 - 335
Gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) arise primarily in the midline of the central nervous system of young children,... 
HETEROGENEITY | STEM-CELLS | GLIOBLASTOMA | MULTIDISCIPLINARY SCIENCES | MUTATION | MOUSE | Oligodendroglia - metabolism | Cell Proliferation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Humans | Brain Neoplasms - pathology | Carcinogenesis - genetics | Brain Neoplasms - genetics | Mitogen-Activated Protein Kinase 7 - genetics | Glioma - genetics | Oligodendroglia - pathology | Sequence Analysis, RNA - methods | Receptor, Platelet-Derived Growth Factor alpha - genetics | Single-Cell Analysis - methods | Glioma - pathology | Histones - metabolism | Mutation | Oncogenes | RNA sequencing | Histones | Genetic aspects | Gliomas | Health aspects | Methods | Cell proliferation | Therapeutic applications | Brain tumors | Central nervous system | Methionine | Ribonucleic acid--RNA | Glial stem cells | Gene sequencing | Signaling | Hierarchies | Model matching | Precursors | Glioma cells | Stem cells | Genetics | Tumorigenesis | Children | Histone H3 | Cancer | Tumors | Index Medicus
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10. Full Text Intensive Multimodality Treatment for Children With Newly Diagnosed CNS Atypical Teratoid Rhabdoid Tumor
by Susan N. Chi and Mary Ann Zimmerman and Xiaopan Yao and Kenneth J. Cohen and Peter Burger and Jaclyn A. Biegel and Lucy B. Rorke-Adams and Michael J. Fisher and Anna Janss and Claire Mazewski and Stewart Goldman and Peter E. Manley and Daniel C. Bowers and Anne Bendel and Joshua Rubin and Christopher D. Turner and Karen J. Marcus and Liliana Goumnerova and Nicole J. Ullrich and Mark W. Kieran
Journal of Clinical Oncology, ISSN 0732-183X, 01/2009, Volume 27, Issue 3, pp. 385 - 389
Purpose Atypical teratoid rhabdoid tumor (ATRT) of the CNS is a highly malignant neoplasm primarily affecting young children, with a historic median survival... 
ONCOLOGY | TERATOID/RHABDOID TUMOR | CENTRAL-NERVOUS-SYSTEM | ATRT | CHILDHOOD | MEDULLOBLASTOMA | CHEMOTHERAPY | INFANCY | RADIATION-THERAPY | Rhabdoid Tumor - drug therapy | Prognosis | Prospective Studies | Infratentorial Neoplasms | Humans | Rhabdoid Tumor - mortality | Child, Preschool | Rhabdoid Tumor - radiotherapy | Combined Modality Therapy | Brain Neoplasms - drug therapy | Teratoma - mortality | Rhabdoid Tumor - therapy | Young Adult | Teratoma - radiotherapy | Teratoma - drug therapy | Adolescent | Brain Neoplasms - therapy | Teratoma - therapy | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Child | Supratentorial Neoplasms | Index Medicus | Pediatric Oncology
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11. Full Text 141 Natural History and Management of Incidentally Discovered Focal Brain Lesions of Uncertain Etiology in Children
by Zaazoue, Mohamed A and Manley, Peter E and Kapur, Kush and Ullrich, Nicole J and Silvera, V Michelle and Goumnerova, Liliana
Neurosurgery, ISSN 0148-396X, 09/2017, Volume 64, Issue CN_suppl_1, pp. 233 - 233
Abstract INTRODUCTION The discovery of incidental brain lesions in children has increased recently due to the widespread usage of neuroimaging. A standardized... 
Pediatrics | Surgery | Tumors
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12. Full Text Incidence, risk factors, and longitudinal outcome of seizures in long‐term survivors of pediatric brain tumors
by Ullrich, Nicole J and Pomeroy, Scott L and Kapur, Kush and Manley, Peter E and Goumnerova, Liliana C and Loddenkemper, Tobias
Epilepsia, ISSN 0013-9580, 10/2015, Volume 56, Issue 10, pp. 1599 - 1604
ObjectiveSeizures are common during and after treatment for a primary brain tumor. Our objective was to describe the incidence and risk factors for seizures in... 
Brain tumor | Oncology | Seizure | Pediatric | Epilepsy | PRESENTING SYMPTOM | ADULT SURVIVORS | CLASSIFICATION | DISORDERS | CHILDHOOD-CANCER SURVIVOR | CLINICAL NEUROLOGY | CHILDREN | SEQUELAE | CENTRAL-NERVOUS-SYSTEM | SPECTRUM | Pediatrics | Humans | Risk Factors | Male | Brain Neoplasms - complications | Epilepsy - etiology | Epilepsy - epidemiology | Incidence | Adolescent | Female | Brain Neoplasms - mortality | Child | Brain Neoplasms - epidemiology | Cohort Studies | Chemotherapy | Brain tumors | Electroencephalography | Seizures (Medicine) | Risk factors | Cancer | Index Medicus
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13. Full Text Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1
by Lori A. Ramkissoon and Peleg M. Horowitz and Justin M. Craig and Shakti H. Ramkissoon and Benjamin E. Rich and Steven E. Schumacher and Aaron McKenna and Michael S. Lawrence and Guillaume Bergthold and Priscilla K. Brastianos and Barbara Tabak and Matthew D. Ducar and Paul Van Hummelen and Laura E. MacConaill and Tina Pouissant-Young and Yoon-Jae Cho and Hala Taha and Madeha Mahmoud and Daniel C. Bowers and Linda Margraf and Uri Tabori and Cynthia Hawkins and Roger J. Packer and D. Ashley Hill and Scott L. Pomeroy and Charles G. Eberhart and Ian F. Dunn and Liliana Goumnerova and Gad Getz and Jennifer A. Chan and Sandro Santagata and William C. Hahn and Charles D. Stiles and Azra H. Ligon and Mark W. Kieran and Rameen Beroukhim and Keith L. Ligon
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 20, pp. 8188 - 8193
Pediatrie low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from BRAF kinase mutations or duplications in specific... 
Pediatrics | Transcription factors | Glioma | Genomics | Genomes | Sequencing | Genetic mutation | Astrocytoma | Tumors | Cancer | A-myb | ACGH | MAPK PATHWAY ACTIVATION | MULTIDISCIPLINARY SCIENCES | ASTROCYTOMAS | aCGH | BRAF FUSION GENE | GLIOBLASTOMA | cancer | CENTRAL-NERVOUS-SYSTEM | DUPLICATION | MUTATIONS | COPY-NUMBER ALTERATION | DNA-SEQUENCING DATA | Protein Structure, Tertiary | Multigene Family | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Male | Proto-Oncogene Proteins - genetics | Sequence Analysis, DNA | Glioma - genetics | Animals | Comparative Genomic Hybridization | Mice, Nude | Glioma - pathology | Alleles | Trans-Activators - genetics | Cell Line, Tumor | Mice | Mutation | Child | 3T3 Cells | Cohort Studies | Cell growth | Rodents | Gene expression | Molecular biology | Index Medicus | Biological Sciences
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14. Full Text Long-term visual outcomes of optic pathway gliomas in pediatric patients without neurofibromatosis type 1
by Wan, Michael J and Ullrich, Nicole J and Manley, Peter E and Kieran, Mark W and Goumnerova, Liliana C and Heidary, Gena
Journal of Neuro-Oncology, ISSN 0167-594X, 8/2016, Volume 129, Issue 1, pp. 173 - 178
Sporadic optic pathway gliomas (OPGs) have been reported to cause more vision loss than OPGs associated with neurofibromatosis type-1, but long-term visual... 
Neurology | Medicine & Public Health | Glioma | Juvenile pilocytic astrocytoma | Visual pathways | Oncology | Neurofibromatosis 1 | Visual acuity | Optic nerve glioma | CARBOPLATIN | PROGNOSTIC-FACTORS | FREE SURVIVAL | FOLLOW-UP | TUMORS | LOW-GRADE GLIOMAS | CHEMOTHERAPY | CLINICAL NEUROLOGY | CHILDREN | PILOCYTIC ASTROCYTOMAS | ONCOLOGY | PROGRESSION | Optic Nerve Neoplasms - complications | Humans | Risk Factors | Child, Preschool | Optic Nerve Glioma - complications | Male | Visual Acuity | Disease-Free Survival | Adolescent | Neurofibromatosis 1 - complications | Female | Retrospective Studies | Visual Pathways - pathology | Child | Cohort Studies | Vision Disorders - etiology | Pediatrics | Gliomas | Patient outcomes | Neurofibromatosis | Children's hospitals | Resveratrol | Development and progression | Children | Ophthalmology | Health aspects | Index Medicus
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15. Full Text Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
by Park, Tae-Eun and Mustafaoglu, Nur and Herland, Anna and Hasselkus, Ryan and Mannix, Robert and FitzGerald, Edward A and Prantil-Baun, Rachelle and Watters, Alexander and Henry, Olivier and Benz, Maximilian and Sanchez, Henry and McCrea, Heather J and Goumnerova, Liliana Christova and Song, Hannah W and Palecek, Sean P and Shusta, Eric and Ingber, Donald E
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2621 - 12
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many pharmaceuticals and therapeutic antibodies to the central nervous... 
IN-VITRO | EFFLUX TRANSPORTERS | INHIBITION | VIVO | PERMEABILITY | MODELS | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | DIFFERENTIATION | HIF-1-ALPHA | P-GLYCOPROTEIN | Drugs | Efflux | Cell culture | Brain | Drug delivery systems | Immunoglobulins | Peptides | Astrocytes | Brain stem | Central nervous system | Antibodies | Selectivity | Drug delivery | Drug development | Endothelium | Blood-brain barrier | Stem cells | Pericytes | Hypoxia | Microvasculature | Pluripotency | Microfluidics | Index Medicus
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