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Journal Article
Rapid Communications in Mass Spectrometry, ISSN 0951-4198, 11/2019, Volume 33, Issue 21, pp. 1643 - 1651
Rationale The complexity of central nervous system (CNS) drug delivery is the main obstacle with the blood–brain barrier (BBB) known to restrict access of most... 
Spectroscopy | Brain | Antiretroviral drugs | Drug delivery systems | Cerebral cortex | Central nervous system | Ions | Liquid chromatography | Desorption | Chromatography | Spatial distribution | Penetration | Ionization | Scientific imaging | Mass spectrometry | Deposition | Pharmaceuticals
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2017, Volume 56, Issue 15, pp. 4100 - 4109
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 05/2015, Volume 2015, Issue 13, pp. 2861 - 2867
We report a mild and efficient Cu(OAc)2‐catalysed protocol for the oxidative C–N cross‐coupling of terminal alkynes and N‐deprotected sulfonimidamides. The... 
C–H activation | C–N coupling | Sulfonimidamides | Synthetic methods | Sulfur | Copper | Alkynes | C-H activation | C-N coupling
Journal Article
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 02/2018, Volume 59, Issue 2, pp. 334 - 339
Ubiquicidin is an antimicrobial peptide with great potential for nuclear imaging of infectious diseases, as its cationic-rich fragment TGRAKRRMQYNRR (UBI) has... 
Ga-NOTA-UBI(29-41) | UBI29-41 | Infection imaging | PET/CT imaging | Ubiquicidin
Journal Article
Journal of Molecular Histology, ISSN 1567-2379, 12/2019, Volume 50, Issue 6, pp. 593 - 599
Central nervous system (CNS) HIV infection causes brain tissue inflammation and tissue deficit that contributes to neuroAIDS. This complication is escalated by... 
Life Sciences | Biomedicine, general | BBB | Pharmacokinetics and mass spectrometric imaging | HIV | CNS | Developmental Biology | NeuroAIDS | Cell Biology | Neuroimaging | Antiretroviral drugs | Nevirapine | Blood-brain barrier | Neurodegeneration | Human immunodeficiency virus--HIV | Central nervous system | Mass spectroscopy | Localization
Journal Article
ChemPhysChem, ISSN 1439-4235, 05/2019, Volume 20, Issue 9, pp. 1126 - 1134
β‐lactam antibiotics, which are used to treat infectious diseases, are currently the most widely used class of antibiotics. This study focused on the chemical... 
β-lactam antibiotics | activation energy | force constant (FC) | transition state (TS) | ring strain energy (RSE)
Journal Article
Assay and Drug Development Technologies, ISSN 1540-658X, 10/2019, Volume 17, Issue 7, pp. 322 - 329
The central nervous system has been identified as an anatomical reservoir for HIV due the difficulties in delivering therapeutic agents into the brain and this... 
Drugs | Neuroimaging | Brain | Spectroscopy | Cerebral cortex | Cortex | Central nervous system | Globus pallidus | Ions | Lamivudine | Mass spectroscopy | Cognition | Liquid chromatography | Pharmacology | Chemical compounds | Corpus callosum | Blood-brain barrier | Neurodegeneration | Human immunodeficiency virus--HIV | Neostriatum | Scientific imaging | Pharmacokinetics | Mass spectrometry | Zidovudine
Journal Article
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 02/2018, Volume 59, Issue 2, pp. 334 - 339
Journal Article