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by Peifer, Martin and Fernández-Cuesta, Lynnette and Sos, Martin L and George, Julie and Seidel, Danila and Kasper, Lawryn H and Plenker, Dennis and Leenders, Frauke and Sun, Ruping and Zander, Thomas and Menon, Roopika and Koker, Mirjam and Dahmen, Ilona and Müller, Christian and Di Cerbo, Vincenzo and Schildhaus, Hans-Ulrich and Altmüller, Janine and Baessmann, Ingelore and Becker, Christian and De Wilde, Bram and Vandesompele, Jo and Böhm, Diana and Ansén, Sascha and Gabler, Franziska and Wilkening, Ines and Heynck, Stefanie and Heuckmann, Johannes M and Lu, Xin and Carter, Scott L and Cibulskis, Kristian and Banerji, Shantanu and Getz, Gad and Park, Kwon-Sik and Rauh, Daniel and Grütter, Christian and Fischer, Matthias and Pasqualucci, Laura and Wright, Gavin and Wainer, Zoe and Russell, Prudence and Petersen, Iver and Chen, Yuan and Stoelben, Erich and Ludwig, Corinna and Schnabel, Philipp and Hoffmann, Hans and Muley, Thomas and Brockmann, Michael and Engel-Riedel, Walburga and Muscarella, Lucia A and Fazio, Vito M and Groen, Harry and Timens, Wim and Sietsma, Hannie and Thunnissen, Erik and Smit, Egber and Heideman, Daniëlle A. M and Snijders, Peter J. F and Cappuzzo, Federico and Ligorio, Claudia and Damiani, Stefania and Field, John and Solberg, Steinar and Brustugun, Odd Terje and Lund-Iversen, Marius and Sänger, Jörg and Clement, Joachim H and Soltermann, Alex and Moch, Holger and Weder, Walter and Solomon, Benjamin and Soria, Jean-Charles and Validire, Pierre and Besse, Benjamin and Brambilla, Elisabeth and Brambilla, Christian and Lantuejoul, Sylvie and Lorimier, Philippe and Schneider, Peter M and Hallek, Michael and Pao, William and Meyerson, Matthew and Sage, Julien and Shendure, Jay and Schneider, Robert and Büttner, Reinhard and Wolf, Jürgen and Nürnberg, Peter and Perner, Sven and Heukamp, Lukas C and Brindle, Paul K and Haas, Stefan and Thomas, Roman K
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1104 - 1110
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 51, pp. 20251 - 20256
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2009, Volume 131, Issue 37, pp. 13286 - 13296
Journal Article
Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7343, pp. 361 - 365
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus... 
HIV-1 | CYCLOPHILIN-A | UNANCHORED POLYUBIQUITIN CHAINS | TRIM5-ALPHA PROTEIN | RECOGNITION | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | RESISTANCE | INFECTION | RESTRICTION | Capsid - chemistry | Receptors, Pattern Recognition - immunology | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Transcription Factor AP-1 - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | HIV-1 - chemistry | HEK293 Cells | Carrier Proteins - immunology | Cell Line | Retroviridae - chemistry | Ubiquitin-Protein Ligases - metabolism | Retroviridae - immunology | MAP Kinase Kinase Kinases - metabolism | Transcription Factors - metabolism | Capsid - immunology | Carrier Proteins - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Carrier Proteins - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Signal transduction | Efficiency | RNA polymerase | Pattern recognition | Kinases | Evacuations & rescues | Immune system | HIV-1/immunology | Capsid/immunology | Life Sciences | MAP Kinase Kinase Kinases/metabolism | Carrier Proteins/immunology | Immunology | Transcription Factors/metabolism | Capsid/chemistry | HIV-1/chemistry | Ubiquitin/metabolism | Receptors, Pattern Recognition/immunology | Retroviridae/chemistry | Ubiquitin-Protein Ligases/immunology | Ubiquitin-Conjugating Enzymes/metabolism | HumansImmunity, Innate/immunology | Lipopolysaccharides/pharmacology | Signal Transduction/drug effects | Retroviridae/immunology | Transcription Factor AP-1/metabolism | Lipopolysaccharides/immunology | Ubiquitin-Protein Ligases/metabolism | Carrier Proteins/genetics | Signal Transduction/immunology | NF-kappa B/metabolism | Ubiquitin-Protein Ligases/genetics | Carrier Proteins/metabolism | Receptors, Pattern Recognition/metabolism
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Journal of Virology, ISSN 0022-538X, 04/2009, Volume 83, Issue 7, pp. 3365 - 3373
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
B30.2(SPRY) DOMAIN | VIROLOGY | SYSTEMATIC MUTATIONAL ANALYSIS | HUMAN-CELLS | CYTOPLASMIC BODIES | IMMUNODEFICIENCY-VIRUS TYPE-1 | MURINE LEUKEMIA-VIRUS | HIGH-TITER | B30.2/SPRY DOMAIN | MULTIPLE SEQUENCE ALIGNMENT | SIMIAN IMMUNODEFICIENCY | Virus-Cell Interactions
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2009, Volume 131, Issue 51, pp. 18478 - 18488
Small molecule kinase inhibitors are an attractive means to modulate kinase activities in medicinal chemistry and chemical biology research. In the... 
ACTIVATION | MECHANISM | PHARMACOPHORE APPROACH | BINDING-SITE | RUTAECARPINE | OPTIMIZATION | CHEMISTRY, MULTIDISCIPLINARY | ALLOSTERIC INHIBITORS | DISCOVERY | P38 MAP KINASE | ATP-BINDING
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2009, Volume 106, Issue 27, pp. 11061 - 11066
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 02/2012, Volume 8, Issue 2, pp. 141 - 143
Until now, a lack of inhibitors with high potency and selectivity in vivo has hampered investigation of the p38 mitogen-activated protein kinase (MAPK)... 
CELLS | ADHESION | SIGNALING PATHWAYS | DESIGN | PLAYS | MAP KINASE | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KAPPA-B | EXPRESSION | Proteins | Biochemistry | Kinases | Molecular biology
Journal Article