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1. Full Text Rare variants are common in schizophrenia
by Gratten, Jacob
Nature neuroscience, ISSN 1097-6256, 10/2016, Volume 19, Issue 11, pp. 1426 - 1428
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Schizophrenia | Genetic Predisposition to Disease | Polymorphism, Single Nucleotide | Humans | Physiological aspects | Genetic aspects | Research | Genetic variation | Risk factors | Index Medicus
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2. Full Text Genetic pleiotropy in complex traits and diseases: Implications for genomic medicine
by Gratten, Jacob and Visscher, Peter M
Genome medicine, ISSN 1756-994X, 07/2016, Volume 8, Issue 1, pp. 78 - 78
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Psychotic Disorders - diagnosis | Genome-Wide Association Study | Quantitative Trait, Heritable | Rett Syndrome - diagnosis | Humans | Genotype | Genetic Pleiotropy | Arthritis, Rheumatoid - pathology | Genetic Variation | Arthritis, Rheumatoid - genetics | Phenotype | Psychotic Disorders - genetics | Animals | Epistasis, Genetic | Rett Syndrome - pathology | Psychotic Disorders - pathology | Models, Genetic | Quantitative Trait Loci | Rett Syndrome - genetics | Arthritis, Rheumatoid - diagnosis | Type 2 diabetes | Pleiotropy | Care and treatment | Genomics | Genetic aspects | Research | Risk factors | Editing | Cardiovascular disease | Genomes | Gene expression | Medicine | Studies | Genotype & phenotype | Body mass index | Coronary vessels | Rheumatoid arthritis | DNA methylation | Mutation | Diabetes | Deoxyribonucleic acid--DNA | Index Medicus
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3. Full Text Large-scale genomics unveils the genetic architecture of psychiatric disorders
by Gratten, Jacob and Wray, Naomi R and Keller, Matthew C and Visscher, Peter M
Nature neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 6, pp. 782 - 790
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Mental Disorders - genetics | Genetic Predisposition to Disease - genetics | Animals | Genomics | Humans | Polymorphism, Single Nucleotide - genetics | Genetic Variation - genetics | Mental Disorders - diagnosis | Genetic aspects | Research | Genetic variation | Mental illness | Risk factors | Index Medicus
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4. Full Text Sizing up whole-genome sequencing studies of common diseases
by Wray, Naomi R and Gratten, Jacob
Nature genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 635 - 637
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Autism Spectrum Disorder | Genome-Wide Association Study | High-Throughput Nucleotide Sequencing | Humans | Medical research | Genomics | Genetic research | Medicine, Experimental | Genomes | Genetic aspects | Nucleotide sequencing | DNA sequencing | Studies | Hypotheses | Annotations | Disease | Families & family life | Mutation | Gene sequencing
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5. Full Text Life history trade-offs at a single locus maintain sexually selected genetic variation
by Johnston, Susan E and Gratten, Jacob and Berenos, Camillo and Pilkington, Jill G and Clutton-Brock, Tim H and Pemberton, Josephine M and Slate, Jon
Nature (London), ISSN 0028-0836, 2013, Volume 502, Issue 7469, pp. 93 - 95
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Selection, Genetic | Reproduction - genetics | Genotype | Male | Mating Preference, Animal - physiology | Polymorphism, Genetic | Genetic Variation | Phenotype | Animals | Survival Analysis | Female | Horns | Receptors, G-Protein-Coupled - genetics | Confidence intervals | Genotype & phenotype | Animal reproduction | Population | Sheep | Gene loci | Males | Success | Index Medicus
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6. Full Text Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations
by Gratten, Jacob and Wray, Naomi R and Peyrot, Wouter J and McGrath, John J and Visscher, Peter M and Goddard, Michael E
Nature genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 718 - 724
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Age Factors | Paternal Age | Genetic Markers - genetics | Humans | Risk Factors | Male | Mutation - genetics | Child | Autistic Disorder - etiology | Schizophrenia - etiology | Gene mutations | Father and child | Aging | Development and progression | Genetic aspects | Mental illness | Population genetics | Identification and classification | Health aspects | Methods | Mental disorders | Schizophrenia | Genomes | Studies | Autism | Hypotheses | Liability | Fathers | Mutation | Behavior | Health risk assessment | Public health | Age | Index Medicus
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7. Full Text Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
by Lee, J.J and Wedow, R and Okbay, A and Kong, E and Maghzian, O and Zacher, M and Galesloot, T.E and Kiemeney, L.A.L.M and Franke, B and Benjamin, D.J and Cesarini, D and 23Me Res Team and Social Sci Genetic Assoc Consortiu and COGENT Cognitive Genomics Consorti and 23andMe Research Team and COGENT (Cognitive Genomics Consortium) and Social Science Genetic Association Consortium and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 2018, Volume 50, Issue 8, pp. 1112 - 1121
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Humans | Middle Aged | Male | Educational Status | Multifactorial Inheritance | Phenotype | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Cohort Studies | Cell interaction | Genome-wide association studies | Usage | Analysis | Multifactorial traits | Research | Health education | Brain | Phenotypes | Dosage compensation | Sample size | Cognitive ability | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Estimates | Environmental effects | Educational attainment | Meta-analysis | Consortia | Education | X Chromosomes | Genetic analysis | Heritability | Index Medicus | Clinical Medicine | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi | Klinisk medicin
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8. Full Text Genome-wide association study identifies 74 loci associated with educational attainment
by Okbay, Aysu and Beauchamp, Jonathan and Fontana, M.A and Lee, James J and Pers, Tune and Rietveld, C.A and Turley, Patrick and Chen, G.-B and Emilsson, Valur and Meddens, S.F.W and Oskarsson, S and Pickrell, J.K and Thom, K and Timshel, P and Vlaming, Ronald and Abdellaoui, Abdel and Ahluwalia, Tarunveer Singh and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, G and Brandsma, Johan and Pina Concas, M and Derringer, J and Furlotte, N.A and Galesloot, Tessel and Girotto, S and Gupta, R and Hall, Leanne M and Harris, Sarah and Hofer, E and Horikoshi, M and Huffman, Jennifer E and Kaasik, K and Kalafati, Ioanna-Panagiota and Karlsson, Robert and Kong, Augustine and Lahti, Jari and Lee, Sven and Deleeuw, C and Lind, Penelope and Lindgren, K.-O and Liu, T and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Mike and Most, Peter and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter and Qian, Y and Raitakari, Olli and Rueedi, R and Salvi, E and Schmidt, B and Schraut, K.E and Shi, J and Smith, Albert Vernon and Poot, Raymond and St Pourcain, Beate and Teumer, Alexander and Thorleifsson, Gudmar and Verweij, Niek and Vuckovic, gana and Wellmann, J and Westra, Harm-Jan and Yang, J and Zhao, W and Zhu, Z and Alizadeh, Behrooz and Amin, Najaf and Bakshi, A and Baumeister, Sebastian and Biino, Ginevra and Bønnelykke, Klaus and Boyle, Patricia and Campbell, Harry and Cappuccio, F.P and Davies, Gail and Neve, Jan-Emmanuel and Deloukas, Panagiotis and Demuth, Ilja and Ding, J and Eibich, P and Eisele, L and Eklund, Niina and Evans, David and Faul, Jessica D and Feitosa, Mary Furlan and Forstner, Aneas and Gandin, Ilaria and Gunnarsson, B and Halldorsson, Bjarni and Harris, Tamara and Holliday, Elizabeth and Heath, Anew C and Hocking, L.J and Homuth, Georg and Horan, Mike and ... and LifeLines Cohort Study and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature (London), ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genome-Wide Association Study | Gene Expression Regulation - genetics | Humans | Molecular Sequence Annotation | Computational Biology | Fetus - metabolism | United Kingdom | Cognition | Educational Status | Bipolar Disorder - genetics | Gene-Environment Interaction | Brain - metabolism | Schizophrenia - genetics | Polymorphism, Single Nucleotide - genetics | Alzheimer Disease - genetics | Quantitative trait loci | Academic achievement | Genome-wide association studies | Genetic aspects | Observations | Studies | Genomes | Gene expression | Genes | Educational attainment | Meta-analysis | Index Medicus | Quantitative Finance | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi
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9. Full Text Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease
by Gratten, Jacob and Visscher, Peter M and Mowry, Bryan J and Wray, Naomi R
Nature genetics, ISSN 1061-4036, 03/2013, Volume 45, Issue 3, pp. 234 - 238
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Autistic Disorder - genetics | Genetic Predisposition to Disease | Schizophrenia - genetics | Genetic Association Studies | Pedigree | Humans | Exons - genetics | Mutation | Open Reading Frames - genetics | Genetic Linkage | Quantitative genetics | Gene mutations | Genetic variation | Neuropsychiatry | Nucleotide sequencing | Research | Methods | DNA sequencing | Proteins | Studies | Genetics | Genes | Index Medicus
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10. Full Text Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
by Nalls, Mike A and Blauwendraat, Cornelis and Vallerga, Costanza L and Heilbron, Karl and Bandres-Ciga, Sara and Chang, Diana and Tan, Manuela and Kia, Demis A and Noyce, Alastair J and Xue, Angli and Bras, Jose and Young, Emily and von Coelln, Rainer and Simón-Sánchez, Javier and Schulte, Claudia and Sharma, Manu and Krohn, Lynne and Pihlstrøm, Lasse and Siitonen, Ari and Iwaki, Hirotaka and Leonard, Hampton and Faghri, Faraz and Gibbs, J Raphael and Hernandez, Dena G and Scholz, Sonja W and Botia, Juan A and Martinez, Maria and Corvol, Jean-Christophe and Lesage, Suzanne and Jankovic, Joseph and Shulman, Lisa M and Sutherland, Margaret and Tienari, Pentti and Majamaa, Kari and Toft, Mathias and Andreassen, Ole A and Bangale, Tushar and Brice, Alexis and Yang, Jian and Gan-Or, Ziv and Gasser, Thomas and Heutink, Peter and Shulman, Joshua M and Wood, Nicholas W and Hinds, David A and Hardy, John A and Morris, Huw R and Gratten, Jacob and Visscher, Peter M and Graham, Robert R and Singleton, Andrew B and Adarmes-Gómez, Astrid D and Aguilar, Miquel and Aitkulova, Akbota and Akhmetzhanov, Vadim and Alcalay, Roy N and Alvarez, Ignacio and Alvarez, Victoria and Bandres-Ciga, Sara and Barrero, Francisco Javier and Bergareche Yarza, Jesús Alberto and Bernal-Bernal, Inmaculada and Billingsley, Kimberley and Blauwendraat, Cornelis and Blazquez, Marta and Bonilla-Toribio, Marta and Botía, Juan A and Boungiorno, María Teresa and Bras, Jose and Brice, Alexis and Brockmann, Kathrin and Bubb, Vivien and Buiza-Rueda, Dolores and Cámara, Ana and Carrillo, Fátima and Carrión-Claro, Mario and Cerdan, Debora and Chelban, Viorica and Clarimón, Jordi and Clarke, Carl and Compta, Yaroslau and Cookson, Mark R and Corvol, Jean-Christophe and Craig, David W and Danjou, Fabrice and Diez-Fairen, Monica and Dols-Icardo, Oriol and Duarte, Jacinto and Duran, Raquel and Escamilla-Sevilla, Francisco and Escott-Price, Valentina and Ezquerra, Mario and Faghri, Faraz and Feliz, Cici and Fernández, Manel and Fernández-Santiago, Rubén and Finkbeiner, Steven and Foltynie, Thomas and Gan-Or, Ziv and Garcia, Ciara and ... and 23andMe Research Team and International Parkinson's Disease Genomics Consortium and System Genomics of Parkinson's Disease Consortium and Int Parkinson's Dis Genomics and Syst Genomics Parkinson's Dis and 23 Me Res Team
Lancet neurology, ISSN 1474-4422, 12/2019, Volume 18, Issue 12, pp. 1091 - 1102
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Phenotypes | Parkinson's disease | Neurodegenerative diseases | Genomics | Parkinsons disease | Cognitive ability | Clinical trials | Genomes | Single-nucleotide polymorphism | Gene expression | Putamen | Risk factors | Datasets | Studies | Prediction models | DNA methylation | Aging | Heritability | Movement disorders | Index Medicus
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