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Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. SCI-19 - SCI-19
Somatic mutations in genes that are involved in pre-mRNA splicing (i.e., spliceosome genes) occur in ~50% of patients with myelodysplastic syndromes (MDS).... 
Journal Article
Blood, ISSN 0006-4971, 03/2017, Volume 129, Issue 10, pp. 1260 - 1269
Alternative splicing generates a diversity of messenger RNA (mRNA) transcripts from a single mRNA precursor and contributes to the complexity of our proteome.... 
U2AF1 MUTATIONS | RING SIDEROBLASTS | CHRONIC LYMPHOCYTIC-LEUKEMIA | ACUTE MYELOID-LEUKEMIA | SF3B1 MUTATIONS | HEMATOLOGY | SRSF2 MUTATIONS | MYELODYSPLASTIC SYNDROMES | SOMATIC MUTATIONS | PRE-MESSENGER-RNA | CHRONIC MYELOMONOCYTIC LEUKEMIA | Hematologic Neoplasms - genetics | Animals | Mutation | RNA Splicing Factors - genetics | Humans | Review
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1064 - 1066
Journal Article
Oncotarget, ISSN 1949-2553, 04/2019, Volume 10, Issue 27, p. 2581
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 21, pp. 2023 - 2036
Journal Article
Leukemia, ISSN 0887-6924, 07/2011, Volume 25, Issue 7, pp. 1153 - 1158
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2018, Volume 24, Issue 1, pp. 7 - 9
A Children's Oncology Group study of nearly 1,000 pediatric acute myeloid leukemia (AML) cases reveals marked differences between the genomic landscapes of... 
AML | MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | IDH2 | MUTATIONS | CELL BIOLOGY | Mutation | Leukemia, Myeloid, Acute | Child | Genomics | Humans | Pediatrics | Reports | Care and treatment | Genetic aspects | Cancer | Children | Myeloid leukemia | Acute myeloid leukemia | Leukemia
Journal Article
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 552 - 555
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 12, pp. 1090 - 1098
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7382, pp. 506 - 510
Journal Article
Cell, ISSN 0092-8674, 07/2012, Volume 150, Issue 2, pp. 264 - 278
Journal Article