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Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 08/2013, Volume 33, Issue 16, pp. 3063 - 3063
Journal Article
Cell Reports, ISSN 2211-1247, 10/2014, Volume 7, Issue 1, pp. 86 - 93
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably(1,2).... 
GROWTH-FACTOR RECEPTOR | BRAF INHIBITOR | RAF INHIBITION | CELLS | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | DIFFERENTIATION | C-JUN | CANCER | EXPRESSION | EGFR | Receptor, Epidermal Growth Factor - genetics | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Gene Library | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2015, Volume 25, Issue 4, pp. 445 - 458
Recurrent inactivating mutations in components of SWI/SNF chromatin-remodeling complexes have been identified across cancer types, supporting their roles as... 
ALK | 抑制剂 | 肿瘤抑制 | 表皮生长因子 | 非小细胞肺癌 | MET | EGFR | SMARCE1 | EGFR signaling | RNAi screening | Drug resistance | SWI/SNF | ACTIVATION | BRAF(V600E) INHIBITION | GERM-LINE | REMODELING GENE ARID1A | SOMATIC MUTATIONS | CELL BIOLOGY | SMALL-CELL CARCINOMA | HYPERCALCEMIC TYPE | RESISTANCE | drug resistance | DIFFERENTIATION | HSNF5/INI1 | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Humans | Lung Neoplasms - pathology | Polycomb Repressive Complex 1 - biosynthesis | Chromosomal Proteins, Non-Histone - biosynthesis | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Quinazolines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - biosynthesis | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Proto-Oncogene Proteins c-met - genetics | Drug Resistance, Neoplasm - genetics | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | DNA-Binding Proteins - biosynthesis | Drug Resistance, Neoplasm - drug effects | Index Medicus | SWI | SNF | Original
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. LB-240 - LB-240
Journal Article
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