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British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2017, Volume 83, Issue 12, pp. 2595 - 2598
Journal Article
CPT: Pharmacometrics & Systems Pharmacology, ISSN 2163-8306, 02/2018, Volume 7, Issue 2, pp. 103 - 110
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 11/2018, Volume 57, Issue 11, pp. 1421 - 1433
Reducing the dose of efavirenz can improve safety, reduce costs, and increase access for patients with HIV infection. According to the World Health... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Pregnancy | Studies | Antiretroviral drugs | Enzymes | Disease transmission | Womens health | Human immunodeficiency virus--HIV | Drug therapy | Patients | Drug dosages | Cost control | Original
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 2009, Volume 26, Issue 12, pp. 2647 - 2656
Journal Article
The Journal of antimicrobial chemotherapy, ISSN 0305-7453, 01/2019, Volume 74, Issue 5, pp. 1348 - 1356
Darunavir 800 mg once (q24h) or 600 mg twice (q12h) daily combined with low-dose ritonavir is used to treat HIV-positive pregnant women. Decreased total... 
PROTEASE INHIBITOR | INFECTIOUS DISEASES | DARUNAVIR | TRANSMISSION | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | PARAMETERS | LOPINAVIR | RITONAVIR | Index Medicus
Journal Article
Toxicology, ISSN 0300-483X, 06/2019, Volume 422, pp. 69 - 75
Many psychoactive substances affect the human dopamine (DA) reuptake transporter (hDAT). Polymorphisms in the encoding gene could affect the functionality of... 
DAT polymorphism | Dopamine reuptake transporter | Designer drugs | CITALOPRAM | INTOXICATION | PLASMA | PHARMACOKINETICS | BUPROPION | SERUM-LEVELS | DRUGS | METHYLPHENIDATE | PHARMACOLOGY & PHARMACY | PHARMACOGENETICS | TOXICOLOGY | BRAIN | Phenols | Serotonin uptake inhibitors | Cocaine | Single nucleotide polymorphisms | Genes
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2017, Volume 157, Issue 2, pp. 500 - 509
Tyrosine kinase inhibitors (TKIs) play an important role in cancer pharmacotherapy, yet there is limited data on their use during pregnancy. We studied... 
Pregnancy | Placental drug disposition | Placental transfer | Tyrosine kinase inhibitors | CANCER-CELLS | placental transfer | TYROSINE KINASE | pregnancy | MODEL | P-GLYCOPROTEIN | tyrosine kinase inhibitors | GROWTH-FACTOR RECEPTOR | LUNG-CANCER | TOXICOLOGY | ALK RECEPTOR | INHIBITORS | EXPRESSION | placental drug disposition
Journal Article
CLINICAL PHARMACOKINETICS, ISSN 0312-5963, 11/2018, Volume 57, Issue 11, pp. 1421 - 1433
BackgroundReducing the dose of efavirenz can improve safety, reduce costs, and increase access for patients with HIV infection. According to the World Health... 
INDIVIDUALS | HIV-1 | 2NN | MIXED-EFFECTS MODELS | CYP2B6 | 1ST-LINE ANTIRETROVIRAL THERAPY | PLASMA-CONCENTRATIONS | PHARMACOLOGY & PHARMACY | FREE DRUG CONCENTRATION | NEVIRAPINE | PREDICTION
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 2011, Volume 44, Issue 4, pp. 487 - 496
It has been reported that polymorphisms in the organic anion transporting polypeptide 1B1 (OATP1B1, SLCO1B1) result in decreased hepatic uptake of simvastatin... 
Transporters | Pharmacokinetics | Statins | NTCP | DRUG | BILE-ACID TRANSPORTERS | PITAVASTATIN | RAT | HMG-COA REDUCTASE | HEPATIC-UPTAKE | UPTAKE SYSTEMS | ANION-TRANSPORTING POLYPEPTIDE | PHARMACOLOGY & PHARMACY | INHIBITOR | ROSUVASTATIN | Estradiol - analogs & derivatives | Fatty Acids, Monounsaturated - pharmacology | Taurocholic Acid - metabolism | Humans | Hepatocytes - metabolism | Sodium - metabolism | Simvastatin - pharmacology | Organic Anion Transporters - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Sodium - deficiency | Indoles - metabolism | Organic Anion Transporters - genetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - metabolism | Transfection | Fatty Acids, Monounsaturated - metabolism | Inhibitory Concentration 50 | Indoles - pharmacology | Biological Transport - drug effects | Molecular Structure | Hepatocytes - drug effects | CHO Cells | Binding, Competitive | Estradiol - metabolism | Cricetinae | Organic Anion Transporters - antagonists & inhibitors | Simvastatin - metabolism | Cells, Cultured | Symporters - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Symporters - genetics | Kinetics | Rifampin - pharmacology | Solute Carrier Organic Anion Transporter Family Member 1b1 | Organic Anion Transporters, Sodium-Dependent - metabolism | Index Medicus
Journal Article