The New England Journal of Medicine, ISSN 0028-4793, 10/2013, Volume 369, Issue 17, pp. 1598 - 1609
Last year, invasive fungal infections were identified in association with injections of contaminated methylprednisolone from a compounding pharmacy. In this...
ASPERGILLUS MENINGITIS | UNITED-STATES | MEDICINE, GENERAL & INTERNAL | SRI-LANKA | LOW-BACK-PAIN | CLADOSPORIUM-CLADOSPORIOIDES | MULTISTATE OUTBREAK | CORTICOSTEROID INJECTION | FACET JOINT INJECTION | STEROID INJECTIONS | EPIDURAL ABSCESS | United States - epidemiology | Glucocorticoids - administration & dosage | Public Health | Humans | Middle Aged | Male | Antifungal Agents - therapeutic use | Meningitis, Fungal - drug therapy | Young Adult | Aspergillus fumigatus - isolation & purification | Disease Outbreaks | Aged, 80 and over | Drug Compounding | Adult | Female | Stroke - epidemiology | Infectious Disease Incubation Period | Meningitis, Fungal - epidemiology | Ascomycota - isolation & purification | Stroke - microbiology | Adolescent | Aged | Injections, Spinal - adverse effects | Drug Contamination | Methylprednisolone - administration & dosage | Complications and side effects | United States | Mortality | Mycoses | Dosage and administration | Research | Diagnosis | Methylprednisolone | Risk factors | Contamination | Health care | Glucocorticoids | Medical records | Data processing | Outbreaks | Infections | Injection | Patients | Morbidity | Fungi | Pain | Meningitis | Acetic acid | Public health
ASPERGILLUS MENINGITIS | UNITED-STATES | MEDICINE, GENERAL & INTERNAL | SRI-LANKA | LOW-BACK-PAIN | CLADOSPORIUM-CLADOSPORIOIDES | MULTISTATE OUTBREAK | CORTICOSTEROID INJECTION | FACET JOINT INJECTION | STEROID INJECTIONS | EPIDURAL ABSCESS | United States - epidemiology | Glucocorticoids - administration & dosage | Public Health | Humans | Middle Aged | Male | Antifungal Agents - therapeutic use | Meningitis, Fungal - drug therapy | Young Adult | Aspergillus fumigatus - isolation & purification | Disease Outbreaks | Aged, 80 and over | Drug Compounding | Adult | Female | Stroke - epidemiology | Infectious Disease Incubation Period | Meningitis, Fungal - epidemiology | Ascomycota - isolation & purification | Stroke - microbiology | Adolescent | Aged | Injections, Spinal - adverse effects | Drug Contamination | Methylprednisolone - administration & dosage | Complications and side effects | United States | Mortality | Mycoses | Dosage and administration | Research | Diagnosis | Methylprednisolone | Risk factors | Contamination | Health care | Glucocorticoids | Medical records | Data processing | Outbreaks | Infections | Injection | Patients | Morbidity | Fungi | Pain | Meningitis | Acetic acid | Public health
Journal Article
JAMA, ISSN 0098-7484, 07/2013, Volume 310, Issue 4, pp. 398 - 407
IMPORTANCE The rabies virus causes a fatal encephalitis and can be transmitted through tissue or organ transplantation. In February 2013, a kidney recipient...
UNITED-STATES | IMMUNE-RESPONSE | MEDICINE, GENERAL & INTERNAL | ADVISORY-COMMITTEE | MANAGEMENT | DONOR | RECOMMENDATIONS | BAT RABIES | ENCEPHALITIS | VACCINATION | DEATHS | Rabies virus - isolation & purification | Rabies - prevention & control | Humans | Male | Rabies virus - genetics | Animals | Rabies Vaccines - therapeutic use | Polymerase Chain Reaction | Rabies - diagnosis | Retrospective Studies | Tissue Donors | Infectious Disease Incubation Period | Raccoons - virology | Rabies - physiopathology | Rabies - transmission | Kidney Transplantation - adverse effects | Prevention | Rabies | Causes of | Organ transplant recipients | Research | Health aspects | Organ donors | Encephalitis | Kidneys | Disease transmission | Transplants & implants | Patients
UNITED-STATES | IMMUNE-RESPONSE | MEDICINE, GENERAL & INTERNAL | ADVISORY-COMMITTEE | MANAGEMENT | DONOR | RECOMMENDATIONS | BAT RABIES | ENCEPHALITIS | VACCINATION | DEATHS | Rabies virus - isolation & purification | Rabies - prevention & control | Humans | Male | Rabies virus - genetics | Animals | Rabies Vaccines - therapeutic use | Polymerase Chain Reaction | Rabies - diagnosis | Retrospective Studies | Tissue Donors | Infectious Disease Incubation Period | Raccoons - virology | Rabies - physiopathology | Rabies - transmission | Kidney Transplantation - adverse effects | Prevention | Rabies | Causes of | Organ transplant recipients | Research | Health aspects | Organ donors | Encephalitis | Kidneys | Disease transmission | Transplants & implants | Patients
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 10/2013, Volume 93, Issue 4, pp. 711 - 720
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous, autosomal-recessive disorder, characterized by oto-sino-pulmonary disease and situs...
CELLS | PROTEIN | GENE | DNAH5 | DISEASE | GENETICS & HEREDITY | OF-FUNCTION MUTATIONS | RETINITIS-PIGMENTOSA | TETRATRICOPEPTIDE REPEAT | CYSTIC KIDNEY | RPGR | Epithelial Cells - metabolism | Humans | Antigens, Surface - genetics | Child, Preschool | Infant | Male | Zebrafish | Kartagener Syndrome - genetics | Mutation - genetics | GTP-Binding Proteins - genetics | Axoneme - genetics | Cilia - genetics | Exome | Young Adult | Phenotype | Animals | Pedigree | Adolescent | Adult | Female | Cytoplasm - genetics | Dyneins - genetics | Child | Ciliary Motility Disorders - genetics | Gene mutations | Cilia and ciliary motion | Physiological aspects | Genetic aspects | Research | Health aspects | Movement disorders | Report
CELLS | PROTEIN | GENE | DNAH5 | DISEASE | GENETICS & HEREDITY | OF-FUNCTION MUTATIONS | RETINITIS-PIGMENTOSA | TETRATRICOPEPTIDE REPEAT | CYSTIC KIDNEY | RPGR | Epithelial Cells - metabolism | Humans | Antigens, Surface - genetics | Child, Preschool | Infant | Male | Zebrafish | Kartagener Syndrome - genetics | Mutation - genetics | GTP-Binding Proteins - genetics | Axoneme - genetics | Cilia - genetics | Exome | Young Adult | Phenotype | Animals | Pedigree | Adolescent | Adult | Female | Cytoplasm - genetics | Dyneins - genetics | Child | Ciliary Motility Disorders - genetics | Gene mutations | Cilia and ciliary motion | Physiological aspects | Genetic aspects | Research | Health aspects | Movement disorders | Report
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 01/2018, Volume 66, Issue 2, p. S38
Journal Article
Disaster Medicine and Public Health Preparedness, ISSN 1935-7893, 10/2018, Volume 12, Issue 5, pp. 606 - 614
ObjectivesThe objectives of this study were to (1) identify available training programs for emergency response personnel and public health professionals on...
hard of hearing | training programs | older adults | emergency preparedness | Deaf | LOCAL HEALTH DEPARTMENTS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | POPULATIONS | DISASTER PREPAREDNESS | HOME | CARE | Health Services Needs and Demand - trends | Humans | Middle Aged | Disaster Planning - methods | Aged | Teaching - standards | Persons With Hearing Impairments - psychology | Disaster Planning - standards | Training | Deafness | Nonprofit organizations | Emergency preparedness
hard of hearing | training programs | older adults | emergency preparedness | Deaf | LOCAL HEALTH DEPARTMENTS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | POPULATIONS | DISASTER PREPAREDNESS | HOME | CARE | Health Services Needs and Demand - trends | Humans | Middle Aged | Disaster Planning - methods | Aged | Teaching - standards | Persons With Hearing Impairments - psychology | Disaster Planning - standards | Training | Deafness | Nonprofit organizations | Emergency preparedness
Journal Article
6.
Full Text
Pediatric Botulism and Use of Equine Botulinum Antitoxin in Children: A Systematic Review
Clinical Infectious Diseases, ISSN 1058-4838, 01/2018, Volume 66, Issue 2, p. S17
Journal Article
Clinical Pediatrics, ISSN 0009-9228, 2/2017, Volume 56, Issue 2, pp. 187 - 189
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 12/2017, Volume 66, Issue suppl_1, pp. S38 - S42
Effective treatment for botulism requires early clinical recognition. Diagnosis of botulism, including during outbreaks, can be challenging. We assessed...
botulism | diagnostic tool | outbreaks | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY
botulism | diagnostic tool | outbreaks | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY
Journal Article
Disaster Medicine and Public Health Preparedness, ISSN 1935-7893, 2018, Volume 13, Issue 3, pp. 639 - 646
Objective Despite children's unique vulnerability, clinical guidance and resources are lacking around the use of radiation medical countermeasures (MCMs)...
medical countermeasures | nuclear | children | radiation | radiologic | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
medical countermeasures | nuclear | children | radiation | radiologic | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Journal Article
10.
Full Text
Surfactant Protein A in Cystic Fibrosis: Supratrimeric Structure and Pulmonary Outcome
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e51050
Background: The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional...
PHAGOCYTOSIS | PSEUDOMONAS-AERUGINOSA | SP-A1 | MULTIDISCIPLINARY SCIENCES | DISEASE | AIRWAY INFLAMMATION | LUNG-FUNCTION | HOST-DEFENSE | OLIGOMERIZATION | BINDING | YOUNG-CHILDREN | Severity of Illness Index | Cystic Fibrosis - metabolism | Cystic Fibrosis - physiopathology | Humans | Bronchoalveolar Lavage | Pulmonary Surfactant-Associated Protein A - analysis | Male | Pulmonary Surfactant-Associated Protein A - metabolism | Adolescent | Adult | Female | Lung - metabolism | Bronchoalveolar Lavage Fluid - chemistry | Chromatography, Gel | Child | Oligomers | Medical research | Surface active agents | Medicine, Experimental | Cystic fibrosis | Bronchitis | Chromatography | Respiratory function | Oligomerization | Control methods | Lung diseases | Bronchus | Inflammation | Protein A | Surfactants | Disease control | Patients | Surfactant protein A | Monomers | Proteins | Gel chromatography | Microorganisms | Bronchoalveolar lavage | Fibrosis | Organizational structure | Agglutination | Alveoli | Structure-function relationships
PHAGOCYTOSIS | PSEUDOMONAS-AERUGINOSA | SP-A1 | MULTIDISCIPLINARY SCIENCES | DISEASE | AIRWAY INFLAMMATION | LUNG-FUNCTION | HOST-DEFENSE | OLIGOMERIZATION | BINDING | YOUNG-CHILDREN | Severity of Illness Index | Cystic Fibrosis - metabolism | Cystic Fibrosis - physiopathology | Humans | Bronchoalveolar Lavage | Pulmonary Surfactant-Associated Protein A - analysis | Male | Pulmonary Surfactant-Associated Protein A - metabolism | Adolescent | Adult | Female | Lung - metabolism | Bronchoalveolar Lavage Fluid - chemistry | Chromatography, Gel | Child | Oligomers | Medical research | Surface active agents | Medicine, Experimental | Cystic fibrosis | Bronchitis | Chromatography | Respiratory function | Oligomerization | Control methods | Lung diseases | Bronchus | Inflammation | Protein A | Surfactants | Disease control | Patients | Surfactant protein A | Monomers | Proteins | Gel chromatography | Microorganisms | Bronchoalveolar lavage | Fibrosis | Organizational structure | Agglutination | Alveoli | Structure-function relationships
Journal Article
Health Security, ISSN 2326-5094, 01/2017, Volume 15, Issue 1, pp. 118 - 122
A timely and effective response to public health threats requires a broad-reaching infrastructure. Children's hospitals are focused on evaluating and managing...
Pediatrics | Hospital preparedness/response | Public health emergency prepredness/response | UNITED-STATES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CDC | EBOLA-VIRUS DISEASE | SYSTEMS | PREPAREDNESS | CRITICAL-CARE | Civil Defense - methods | Public Health | Emergency Medical Services - organization & administration | Humans | Disaster Planning | Hospitals, Pediatric - standards | Hospitals, Pediatric - organization & administration | Pathogens | Epidemics | Physicians | Viral diseases | Viruses | Outbreaks | Patients | Children & youth | Ebola virus | Infectious diseases | Hospitals | Infrastructure | Children | Public health
Pediatrics | Hospital preparedness/response | Public health emergency prepredness/response | UNITED-STATES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CDC | EBOLA-VIRUS DISEASE | SYSTEMS | PREPAREDNESS | CRITICAL-CARE | Civil Defense - methods | Public Health | Emergency Medical Services - organization & administration | Humans | Disaster Planning | Hospitals, Pediatric - standards | Hospitals, Pediatric - organization & administration | Pathogens | Epidemics | Physicians | Viral diseases | Viruses | Outbreaks | Patients | Children & youth | Ebola virus | Infectious diseases | Hospitals | Infrastructure | Children | Public health
Journal Article
12.
Full Text
Pediatric Botulism and Use of Equine Botulinum Antitoxin in Children: A Systematic Review
Clinical Infectious Diseases, ISSN 1058-4838, 12/2017, Volume 66, Issue suppl_1, pp. S17 - S29
Background. Botulism manifests with cranial nerve palsies and flaccid paralysis in children and adults. Botulism must be rapidly identified and treated;...
botulism | botulinum antitoxin | child, bioterrorism | pediatrics | UNITED-STATES | INFECTIOUS DISEASES | MANAGEMENT | MICROBIOLOGY | IMMUNOLOGY
botulism | botulinum antitoxin | child, bioterrorism | pediatrics | UNITED-STATES | INFECTIOUS DISEASES | MANAGEMENT | MICROBIOLOGY | IMMUNOLOGY
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 09/2013, Volume 19, Issue 9, pp. 1514 - 1517
During an investigation of an outbreak of gastroenteritis caused by Salmonella enterica serovar Paratyphi B variant L(+) tartrate(+), we identified...
UNITED-STATES | SURVIVAL | INFECTIOUS DISEASES | STAINLESS-STEEL | CROSS-CONTAMINATION | FOODBORNE DISEASE | SALMONELLA | HEALTH | IMMUNOLOGY | CAMPYLOBACTER | SURFACES | PATHOGENS | Gastroenteritis - epidemiology | Disease Outbreaks | Food Contamination | Gastroenteritis - etiology | Humans | Gastroenteritis - diagnosis | Salmonella enterica - classification | Soy Foods - microbiology | Bacterial Typing Techniques - methods | North Carolina - epidemiology | Food Microbiology | Prevention | Gastroenteritis | Food contamination | Causes of | Research | Health aspects | Epidemiology | Tempeh | Contamination | Salmonella food poisoning | North Carolina | Salmonella enterica serovar Paratyphi B | foodborne illness | tempeh | Salmonella spp | bacteria | food handling | salmonellosis | gastroenteritis | Dispatch | enteric infections | soy foods
UNITED-STATES | SURVIVAL | INFECTIOUS DISEASES | STAINLESS-STEEL | CROSS-CONTAMINATION | FOODBORNE DISEASE | SALMONELLA | HEALTH | IMMUNOLOGY | CAMPYLOBACTER | SURFACES | PATHOGENS | Gastroenteritis - epidemiology | Disease Outbreaks | Food Contamination | Gastroenteritis - etiology | Humans | Gastroenteritis - diagnosis | Salmonella enterica - classification | Soy Foods - microbiology | Bacterial Typing Techniques - methods | North Carolina - epidemiology | Food Microbiology | Prevention | Gastroenteritis | Food contamination | Causes of | Research | Health aspects | Epidemiology | Tempeh | Contamination | Salmonella food poisoning | North Carolina | Salmonella enterica serovar Paratyphi B | foodborne illness | tempeh | Salmonella spp | bacteria | food handling | salmonellosis | gastroenteritis | Dispatch | enteric infections | soy foods
Journal Article
Lancet Respiratory Medicine, The, ISSN 2213-2600, 2017, Volume 5, Issue 7, pp. 557 - 567
Summary Background Lumacaftor and ivacaftor combination treatment showed efficacy in patients aged 12 years or older with cystic fibrosis homozygous for...
Pulmonary/Respiratory | INERT-GAS WASHOUT | IN-VITRO | ABNORMALITIES | RESPIRATORY SYSTEM | CLINICAL-TRIALS | PHE508DEL CFTR | MUTATION | DISEASE | LUNG CLEARANCE INDEX | CFTR POTENTIATOR | YOUNG-CHILDREN | CRITICAL CARE MEDICINE | Humans | Aminopyridines - adverse effects | Male | Chloride Channel Agonists - adverse effects | Benzodioxoles - administration & dosage | Aminophenols - adverse effects | Mucociliary Clearance - drug effects | Forced Expiratory Volume | Sweat - chemistry | Quinolones - adverse effects | Benzodioxoles - adverse effects | Female | Surveys and Questionnaires | Child | Aminopyridines - administration & dosage | Double-Blind Method | Lung - physiopathology | Quinolones - administration & dosage | Chloride Channel Agonists - administration & dosage | Cystic Fibrosis - genetics | Lung - drug effects | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mutation | Aminophenols - administration & dosage | Cystic Fibrosis - drug therapy | Drug Combinations | Cystic fibrosis | Ivacaftor | Dosage and administration | Drug therapy | Clinical trials | Care and treatment | Analysis
Pulmonary/Respiratory | INERT-GAS WASHOUT | IN-VITRO | ABNORMALITIES | RESPIRATORY SYSTEM | CLINICAL-TRIALS | PHE508DEL CFTR | MUTATION | DISEASE | LUNG CLEARANCE INDEX | CFTR POTENTIATOR | YOUNG-CHILDREN | CRITICAL CARE MEDICINE | Humans | Aminopyridines - adverse effects | Male | Chloride Channel Agonists - adverse effects | Benzodioxoles - administration & dosage | Aminophenols - adverse effects | Mucociliary Clearance - drug effects | Forced Expiratory Volume | Sweat - chemistry | Quinolones - adverse effects | Benzodioxoles - adverse effects | Female | Surveys and Questionnaires | Child | Aminopyridines - administration & dosage | Double-Blind Method | Lung - physiopathology | Quinolones - administration & dosage | Chloride Channel Agonists - administration & dosage | Cystic Fibrosis - genetics | Lung - drug effects | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mutation | Aminophenols - administration & dosage | Cystic Fibrosis - drug therapy | Drug Combinations | Cystic fibrosis | Ivacaftor | Dosage and administration | Drug therapy | Clinical trials | Care and treatment | Analysis
Journal Article
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Full Text
Parental Presence at the Bedside of a Child with Suspected Ebola: An Expert Discussion
Clinical Pediatric Emergency Medicine, ISSN 1522-8401, 2015, Volume 17, Issue 1, pp. 81 - 86
The Ebola virus disease (Ebola) outbreak in West Africa (2014-2015) prompted domestic planning to address the scenario in which a traveler imports Ebola into...
Emergency | infection control | family centered care | bioethics | Ebola virus disease | Bioethics | Family centered care | Infection control | Ebola virus | Virus diseases | Parenting | Ebola virus infections | Health care industry | International economic relations | Children | Health aspects | Medical ethics
Emergency | infection control | family centered care | bioethics | Ebola virus disease | Bioethics | Family centered care | Infection control | Ebola virus | Virus diseases | Parenting | Ebola virus infections | Health care industry | International economic relations | Children | Health aspects | Medical ethics
Journal Article
Clinical pediatrics, 02/2017, Volume 56, Issue 2, p. 187
Journal Article
JAMA, ISSN 0098-7484, 02/2012, Volume 307, Issue 8, p. 779
Griffin et al discuss the results of the study conducted by the North Carolina Division of Public Health to identify the source of transmission of Escherichia...
Bacterial infections | Disease transmission | E coli
Bacterial infections | Disease transmission | E coli
Journal Article
JAMA: Journal of the American Medical Association, ISSN 0098-7484, 07/2013, Volume 310, Issue 4, pp. 398 - 398
The rabies virus causes a fatal encephalitis and can be transmitted through tissue or organ transplantation. In February 2013, a kidney recipient with no...
Allografts
Allografts
Journal Article
American Journal of Human Genetics, ISSN 0002-9297, 10/2013, Volume 93, Issue 4, p. 711
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous, autosomal-recessive disorder, characterized by oto-sino-pulmonary disease and situs...
Proteins | Genotype & phenotype | Genetic disorders | Genes | Zebrafish | Mutation | Cytoplasm
Proteins | Genotype & phenotype | Genetic disorders | Genes | Zebrafish | Mutation | Cytoplasm
Journal Article
Morbidity and Mortality Weekly Report, ISSN 0149-2195, 9/2015, Volume 64, Issue 36, pp. 1006 - 1010
The 2014–2015 Ebola virus disease (Ebola) epidemic is the largest in history and represents the first time Ebola has been diagnosed in the United States. On...
PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | Epidemics | United States - epidemiology | Diagnosis, Differential | Humans | Risk Factors | Child, Preschool | Infant | Male | Hemorrhagic Fever, Ebola - epidemiology | Ebolavirus - isolation & purification | Centers for Disease Control and Prevention (U.S.) - utilization | Hemorrhagic Fever, Ebola - diagnosis | Health Facilities | Remote Consultation - statistics & numerical data | Health Personnel | Adolescent | Female | Child | Infant, Newborn | Ebola virus | Medical diagnosis | Public health | Risk factors | Children & youth
PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | Epidemics | United States - epidemiology | Diagnosis, Differential | Humans | Risk Factors | Child, Preschool | Infant | Male | Hemorrhagic Fever, Ebola - epidemiology | Ebolavirus - isolation & purification | Centers for Disease Control and Prevention (U.S.) - utilization | Hemorrhagic Fever, Ebola - diagnosis | Health Facilities | Remote Consultation - statistics & numerical data | Health Personnel | Adolescent | Female | Child | Infant, Newborn | Ebola virus | Medical diagnosis | Public health | Risk factors | Children & youth
Journal Article