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1. Full Text Arsenic trioxide and all- trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial
by Burnett, Alan K, Prof and Russell, Nigel H, Prof and Hills, Robert K, DPhil and Bowen, David, Prof and Kell, Jonathan, MD and Knapper, Steve, DM and Morgan, Yvonne G, PhD and Lok, Jennie, MSc and Grech, Angela, BA and Jones, Gail, MD and Khwaja, Asim, Prof and Friis, Lone, PhD and McMullin, Mary Frances, Prof and Hunter, Ann, MD and Clark, Richard E, Prof and Grimwade, David, Prof and UK National Cancer Research Institute Acute Myeloid Leukaemia Working Group and Natl Canc Res Inst Acute Myeloid
The lancet oncology, ISSN 1470-2045, 2015, Volume 16, Issue 13, pp. 1295 - 1305
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Young Adult | Arsenicals - therapeutic use | Idarubicin - adverse effects | Time Factors | Adult | Female | Leukocyte Count | Idarubicin - therapeutic use | Real-Time Polymerase Chain Reaction | Arsenicals - adverse effects | Oxides - therapeutic use | Kaplan-Meier Estimate | Treatment Outcome | United Kingdom | Oxides - adverse effects | New Zealand | Tretinoin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Adolescent | Intention to Treat Analysis | Leukemia, Promyelocytic, Acute - mortality | Denmark | Quality of Life | Tretinoin - adverse effects | Leukemia, Promyelocytic, Acute - diagnosis | Biomarkers, Tumor - genetics | Leukemia, Promyelocytic, Acute - genetics | Leukemia, Promyelocytic, Acute - drug therapy | Anthracyclines | Product development | Hospitals | Arsenic | Tretinoin | Index Medicus
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2. Full Text Defining minimal residual disease in acute myeloid leukemia: Which platforms are ready for "prime time"?
by Grimwade, David and Freeman, Sylvie D
Blood, ISSN 0006-4971, 11/2014, Volume 124, Issue 23, pp. 3345 - 3355
Life Sciences & Biomedicine | Hematology | Science & Technology | Neoplasm, Residual | Flow Cytometry - methods | Prognosis | Leukemia, Myeloid, Acute - pathology | Bone Marrow - pathology | Humans | Hematopoietic Stem Cell Transplantation | Immunophenotyping | Real-Time Polymerase Chain Reaction | Leukemia, Myeloid, Acute - therapy | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
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3. Full Text Cytogenetics of Childhood Acute Myeloid Leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 12
by Christine J. Harrison and Robert K. Hills and Anthony V. Moorman and David J. Grimwade and Ian Hann and David K.H. Webb and Keith Wheatley and Siebold S.N. de Graaf and Eva van den Berg and Alan K. Burnett and Brenda E.S. Gibson
Journal of clinical oncology, ISSN 0732-183X, 06/2010, Volume 28, Issue 16, pp. 2674 - 2681
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Multivariate Analysis | Confidence Intervals | Prognosis | Humans | Child, Preschool | Fluorescence | Infant | Male | In Situ Hybridization | Karyotyping | Bone Marrow Transplantation | Female | Registries | Retrospective Studies | Cytogenetic Analysis | Genetic Predisposition to Disease - epidemiology | Odds Ratio | Child | Leukemia, Myeloid, Acute - therapy | Risk Assessment | Leukemia, Myeloid, Acute - pathology | Kaplan-Meier Estimate | Proportional Hazards Models | Probability | Logistic Models | Treatment Outcome | United Kingdom | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Chromosome Aberrations | Survival Analysis | Chromosomes, Human, Pair 12 | Chromosomes, Human, Pair 10 | Leukemia, Myeloid, Acute - genetics | Index Medicus
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4. Full Text Assessment of Minimal Residual Disease in Standard-Risk AML
by Ivey, Adam and Hills, Robert K and Simpson, Michael A and Jovanovic, Jelena V and Gilkes, Amanda and Grech, Angela and Patel, Yashma and Bhudia, Neesa and Farah, Hassan and Mason, Joanne and Wall, Kerry and Akiki, Susanna and Griffiths, Michael and Solomon, Ellen and McCaughan, Frank and Linch, David C and Gale, Rosemary E and Vyas, Paresh and Freeman, Sylvie D and Russell, Nigel and Burnett, Alan K and Grimwade, David and UK National Cancer Research Institute AML Working Group
The New England journal of medicine, ISSN 0028-4793, 02/2016, Volume 374, Issue 5, pp. 422 - 433
Recurrence | Prognosis | Humans | Risk Factors | Transcriptome | Molecular Sequence Data | Nuclear Proteins - metabolism | Gene Expression Profiling | Reverse Transcriptase Polymerase Chain Reaction | Neoplasm, Residual - genetics | Exome | Base Sequence | DNA, Neoplasm - analysis | Mutation | Nuclear Proteins - genetics | Leukemia, Myeloid, Acute - genetics | Regression (Disease) | Research | Gene mutations | Biological markers | Health risk assessment | Risk factors | Myeloid leukemia | Leukemia | Genes | Clinical trials | Minimal residual disease | Quantitation | Multivariate analysis | Patients | Polymerase chain reaction | Genetic markers | Chemotherapy | Medical prognosis | Remission | Acute myeloid leukemia | Index Medicus | Abridged Index Medicus
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5. Full Text Defining minimal residual disease in acute myeloid leukemia: Which platforms are ready for "prime time"?
by Grimwade, David and Freeman, Sylvie D
Hematology, ISSN 1520-4391, 12/2014, Volume 2014, Issue 1, pp. 222 - 233
Index Medicus
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6. Full Text A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS
by Amodeo, Valeria and A, Deli and Betts, Joanne and Bartesaghi, Stefano and Zhang, Ying and Richard-Londt, Angela and Ellis, Matthew and Roshani, Rozita and Vouri, Mikaella and Galavotti, Sara and Oberndorfer, Sarah and Leite, Ana Paula and Mackay, Alan and Lampada, Aikaterini and Stratford, Eva Wessel and Li, Ningning and Dinsdale, David and Grimwade, David and Jones, Chris and Nicotera, Pierluigi and Michod, David and Brandner, Sebastian and Salomoni, Paolo
Cell reports (Cambridge), ISSN 2211-1247, 07/2017, Volume 20, Issue 2, pp. 411 - 426
glioblastoma | Slit | neurogenesis | cell migration | Polycomb | nuclear lamina | PML | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Central Nervous System - metabolism | Humans | Cells, Cultured | Cell Movement - physiology | Neurogenesis - genetics | Cell Differentiation - genetics | Animals | Central Nervous System - cytology | Histone-Lysine N-Methyltransferase - metabolism | Nuclear Lamina - metabolism | Neurogenesis - physiology | Promyelocytic Leukemia Protein - metabolism | Glioblastoma - metabolism | Mice | Cell Differentiation - physiology | Index Medicus
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7. Full Text Prognostic Relevance of Treatment Response Measured by Flow Cytometric Residual Disease Detection in Older Patients With Acute Myeloid Leukemia
by Sylvie D. Freeman and Paul Virgo and Steve Couzens and David Grimwade and Nigel Russell and Robert K. Hills and Alan K. Burnett
Journal of clinical oncology, ISSN 0732-183X, 11/2013, Volume 31, Issue 32, pp. 4123 - 4131
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Antibodies, Monoclonal, Humanized - therapeutic use | Prognosis | Leukemia, Myeloid, Acute - pathology | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Immunophenotyping | Male | Antineoplastic Agents - therapeutic use | Neoplasm Recurrence, Local - mortality | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Flow Cytometry | Neoplasm, Residual - diagnosis | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Female | Aged | Neoplasm Recurrence, Local - epidemiology | Aminoglycosides - therapeutic use | Index Medicus
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8. Full Text Just 1 test to diagnose AML?
by Dillon, Richard and Grimwade, David
Blood, ISSN 0006-4971, 07/2016, Volume 128, Issue 1, pp. 7 - 8
Life Sciences & Biomedicine | Hematology | Science & Technology | Leukemia, Myeloid, Acute | Humans | Chromosome Aberrations | Index Medicus | Abridged Index Medicus
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9. Full Text Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance
by Grimwade, David and Ivey, Adam and Huntly, Brian J. P
Blood, ISSN 0006-4971, 01/2016, Volume 127, Issue 1, pp. 29 - 41
Life Sciences & Biomedicine | Hematology | Science & Technology | Young Adult | Leukemia, Myeloid, Acute - diagnosis | Prognosis | Humans | Leukemia, Myeloid, Acute - drug therapy | Adult | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Index Medicus | Abridged Index Medicus | Advances in Acute Myeloid Leukemia | Review Series
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