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Tetrahedron, ISSN 0040-4020, 08/2018, Volume 74, Issue 34, pp. 4489 - 4494
A novel synthetic protocol of ozonolytic cleavage of 18 -oleanane triterpenoid with the five-membered , -alkenenitrile moiety dissolved in dichloromethane to... 
Allobetulone | Ozonolysis | 1,2,4-Trioxolanes | Triterpenoids | 1,3-Secotriterpenoids | Unsaturated nitriles | Lactones | ALLOBETULIN | CHEMISTRY, ORGANIC | ANTIVIRAL ACTIVITY | PENTACYCLIC TRITERPENOIDS | DERIVATIVES
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2018, Volume 28, Issue 23, p. 3752
A set of [beta]-ketoesters was synthesized from 2,3-seco-18[alpha]H-oleanane and 2,3-secolupane bromomethyl ketones. Additionally, hydroxy derivatives with the... 
Chromatin | Analysis | Acetic acid | Aldehydes | Organic acids
Journal Article
STEROIDS, ISSN 0039-128X, 12/2018, Volume 140, pp. 131 - 143
Synthetic transformations of steroids for drug discovery and improvement of drug effectiveness have been an important part of modern medicinal chemistry and... 
URSOLIC ACID | "Triterpenoid-steroid" hybrids | DESIGN | REMOVAL | 3,4-Secotriterpenoids | ANTICANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | Cytotoxicity | INHIBITORS | DERIVATIVES | Molecular docking | Nitriles | Drug discovery | Bisphenol-A | Resveratrol
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2018, Volume 74, Issue 34, p. 4489
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.tet.2018.07.004 
Epoxy resins | Dimethyl sulfide | Nitriles | Lactones
Journal Article
Steroids, ISSN 0039-128X, 12/2018, Volume 140, pp. 131 - 143
Synthetic transformations of steroids for drug discovery and improvement of drug effectiveness have been an important part of modern medicinal chemistry and... 
Cytotoxicity | 3,4-Secotriterpenoids | Molecular docking | “Triterpenoid-steroid” hybrids
Journal Article
Process Biochemistry, ISSN 1359-5113, 01/2017, Volume 52, p. 1
The findings of a comprehensive study on R. rhodochrous IEGM 66 and triterpenoid betulin interactions during its biotransformation were reported. In the... 
Adaptations | Scanning electron microscopy | Atomic force microscopy | Confocal microscopy | Rhodococcus | Bioavailability | Confocal | Experiments | Fatty acids | Fatty acid composition | Microorganisms | Aggregates | Green products | Functional morphology | Biotransformation | Rhodococcus rhodochrous | Oxidation | Cell size | Localization | Viability | Scanning microscopy
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 05/2019, Volume 56, Issue 5, pp. 1634 - 1645
Isoquinolines rank as the second largest group among the plant alkaloids. Natural isoquinolines and synthetic isoquinoline derivatives exhibit numerous... 
CHEMISTRY, ORGANIC | COMPLEX | QUINOL OXIDATION SITE | DERIVATIVES
Journal Article
Journal of hazardous materials, 12/2017, Volume 346, p. 103
Actinobactrial strains Rhodococcus erythropolis IEGM 267 and R. rhodochrous IEGM 107 were used to study biodegradation of dehydroabietic acid (DHA), a toxic... 
Journal Article
Process Biochemistry, ISSN 1359-5113, 11/2013, Volume 48, Issue 11, pp. 1640 - 1644
The ability of actinobacteria to transform betulin to betulone was proved and reported for the first time. Betulone, the product of regioselective oxidation of... 
Regioselective oxidation | Betulin | Betulone | Biotransformation | Rhodococcus rhodochrous | TRANSFORMATION | ENGINEERING, CHEMICAL | BIODEGRADATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRITERPENES | CYTOTOXICITY | Synthesis | Transforms | Rhodococcus | Biochemistry | Conversion | Strain
Journal Article
Tetrahedron, ISSN 0040-4020, 11/2017, Volume 73, Issue 45, pp. 6448 - 6455
A new convenient route to synthesize 1,10-seco-triterpenoids from allobetulin was demonstrated. Stereoisomerism of starting oleanane 1-oximes was determined by... 
Oximes | A-seco-triterpenoids | Herpes simplex virus type I | Triterpenoids | Beckmann rearrangement | Antiviral activity | A-SECO DERIVATIVES | CHEMISTRY, ORGANIC | TRITERPENES | CANCER | LUPANE | BETULINIC ACID | RING | BIOLOGICAL-ACTIVITY | Stereoisomers | Antiviral agents | Epidemiology
Journal Article
Process Biochemistry, ISSN 1359-5113, 01/2017, Volume 52, pp. 1 - 9
The proposed scheme of IEGM 66 cell (1) interaction with betulin (2): betulin issolution (D) in the cell wall (CW) lipids, betulin transport across the... 
Atomic force microscopy | Betulin | Cell-substrate interactions | Rhodococcus rhodochrous IEGM 66 | Confocal laser scanning microscopy | TRANSFORMATION | BACTERIA | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | STEROL | MICROSCOPY | ENGINEERING, CHEMICAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Enzymes | Lipids | Fatty acids
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 10/2019, Volume 28, Issue 10, pp. 1648 - 1660
The effect of the synthetic modifications of the triterpenic A ring on the level of antiviral activity of triterpenic C3, C28 amides with a residue of racemic,... 
Biochemistry, general | Biomedicine | Microbicides | HIV | Betulinic acid | Antiviral activity | Amides | HSV | Pharmacology/Toxicology | Cell Biology | BETULINIC ACID-DERIVATIVES | CHEMISTRY, MEDICINAL | ANTI-HIV | VIRUS TYPE-1 | LUPANE | CHEMISTRY | INHIBITORS | Antiviral agents | HIV (Viruses) | Epidemiology | Analysis | Immunodeficiency
Journal Article
Journal Article
Letters in Organic Chemistry, ISSN 1570-1786, 06/2011, Volume 8, Issue 5, pp. 301 - 308
The resolution of 2-isobornyl-4-methylphenol (+/-)-1 via diastereomers was carried out. The enantioenriched phenols (+)-1, (-)-1 and morpholinomethyl... 
Aminomethylation | Anti-inflammatory activity | Cytotoxicity | Enantiomers | Terpenylphenols | Chiral auxiliaries | X-ray diffraction analysis | chiral auxiliaries | SALICYLIC ALDEHYDES | RESOLUTION | ASSIGNMENT | CHEMISTRY, ORGANIC | terpenylphenols | enantiomers | DERIVATIVES | cytotoxicity | anti-inflammatory activity
Journal Article
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