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science & technology (14) 14
substrate specificity (11) 11
life sciences & biomedicine (10) 10
biochemistry & molecular biology (9) 9
substrates (7) 7
proteases (6) 6
apoptosis (5) 5
enzymes (5) 5
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probe design (2) 2
profiling (2) 2
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Scientific reports, ISSN 2045-2322, 10/2018, Volume 8, Issue 1, pp. 15998 - 10
... of the MALT1 as a strategy for the design of potent substrates and activity- based probes Paulina Kasperkiewicz 1, Sonia Kołt1, Tomasz Janiszewski1, Katarzyna Groborz1... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Enzymes | Arginine | Peptides | Substrate specificity | Mucosa | Amino acids | Protein transport | Lymphoma | Probes | Index Medicus
Journal Article
ISSN 2041-6520, 2/2018, Volume 9, Issue 8, pp. 2113 - 2129
... Vizovisek, c Katarzyna Groborz, a Paulina Kasperkiewicz, ab Darren Finlay, a Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology... 
Journal Article
Chemical science (Cambridge), ISSN 2041-6539, 2018, Volume 9, Issue 8, pp. 2113 - 2129
Highly-selective fluorogenic substrate and activity-based probe for monitoring cathepsin L activity in the breast cancer cell line MDA-MB-231. Cysteine... 
Cysteine | Proteases | Protease | Cathepsin B | Homeostasis | Lysosomes | Fluorescence | Breast cancer | Substrates | Cancer | Immune system
Journal Article
Cell death and differentiation, ISSN 1350-9047, 12/2019, Volume 26, Issue 12, pp. 2695 - 2709
... cleavage in reversine-treated colon cancer cells Marcin Poreba1,2 ● Wioletta Rut2 ● Katarzyna Groborz1,2 ● Scott J. Snipas1 ● Guy S. Salvesen1 ● Marcin Drag1,2... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Caspase-8 | Colon cancer | Cell death | Substrate specificity | Proteinase | Colorectal cancer | Substrate preferences | Caspase-3 | Caspase-2 | Apoptosis | Index Medicus
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 10/2020, Volume 59, Issue 43, pp. 19143 - 19152
Fluorescently quenched probes that are specifically activated in the cancer microenvironment have great potential application for diagnosis, early detection,... 
in-vivo imaging | protease profiling | probe design | disease tissue | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Proteases | Diagnostic imaging | Investigations | Surgical instruments | Enzymes | Profiling | Animal tissues | Fluorescent indicators | Probes | Substrates | Optimization | Combinatorial analysis | Tumors | Index Medicus
Journal Article
Cell death and differentiation, ISSN 1350-9047, 2019, Volume 27, Issue 2, pp. 451 - 465
... strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells Katarzyna Groborz1 ● Monica L. Gonzalez Ramirez2... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Solid phase methods | Caspase-8 | Cell death | Substrate specificity | Inflammation | Caspase inhibitors | Apoptosis | Index Medicus
Journal Article
Antiviral research, ISSN 0166-3542, 03/2020, Volume 175, pp. 104731 - 104731
West Nile virus (WNV) and Dengue virus (DENV) are mosquito-borne pathogenic flaviviruses. The NS2B-NS3 proteases found in these viruses are responsible for... 
West Nile | Serine hydrolase | Proteolytic enzyme | Substrate specificity | Dengue | Zika | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Index Medicus
Journal Article