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Journal of Clinical Oncology, ISSN 0732-183X, 04/2009, Volume 27, Issue 12, pp. 2038 - 2045
Purpose We performed a randomized phase II trial comparing pemetrexed with pemetrexed plus carboplatin (PC) in patients experiencing relapse after... 
RHEUMATOID-ARTHRITIS | TRIAL | POLYMORPHISMS | CISPLATIN | METHYLENETETRAHYDROFOLATE REDUCTASE GENE | 2ND-LINE TREATMENT | METHOTREXATE | DOCETAXEL | UMCG Approved | THYMIDYLATE-SYNTHASE | CHEMOTHERAPY | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Guanine - analogs & derivatives | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Carcinoma, Large Cell - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Methylenetetrahydrofolate Reductase (NADPH2) - genetics | Membrane Transport Proteins - genetics | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | gamma-Glutamyl Hydrolase - genetics | Lung Neoplasms - genetics | Pharmacogenetics | Carcinoma, Non-Small-Cell Lung - genetics | Risk Factors | Carboplatin - administration & dosage | Survival Rate | Treatment Outcome | Adenocarcinoma - drug therapy | Pemetrexed | Thymidylate Synthase - genetics | Adenocarcinoma - secondary | Disease Progression | Reduced Folate Carrier Protein | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Glutamates - administration & dosage | Carcinoma, Squamous Cell - secondary | Polymorphism, Genetic - genetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Guanine - administration & dosage | Index Medicus
Journal Article
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The lancet oncology, ISSN 1470-2045, 06/2015, Volume 16, Issue 6, pp. 630 - 637
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Journal Article
The lancet oncology, ISSN 1470-2045, 10/2017, Volume 18, Issue 10, pp. 1307 - 1316
BRAFV600E mutation occurs in 1–2% of lung adenocarcinomas and acts as an oncogenic driver. Dabrafenib, alone or combined with trametinib, has shown substantial... 
Oncology | Index Medicus
Journal Article
The lancet oncology, ISSN 1470-2045, 07/2016, Volume 17, Issue 7, pp. 984 - 993
Summary Background BRAF mutations act as an oncogenic driver via the mitogen-activated protein kinase (MAPK) pathway in non-small cell lung cancer (NSCLC).... 
Hematology, Oncology and Palliative Medicine
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 08/2017, Volume 35, Issue 22, pp. 2490 - 2498
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Journal of clinical oncology, ISSN 1527-7755, 08/2016, Volume 34, Issue 24, pp. 2866 - 2873
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