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Nature, ISSN 0028-0836, 08/2016, Volume 537, Issue 7619, pp. 229 - 233
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6061, pp. 1372 - 1377
Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against... 
Schizonts | Malaria | RESEARCH ARTICLES | Liver | Antimalarials | Infections | Parasites | Inhibitory concentration 50 | Scaffolds | Blood | Chemicals | RESISTANCE | TARGETS | INFECTIONS | MUTATIONS | MULTIDISCIPLINARY SCIENCES | METHEMOGLOBINEMIA | Plasmodium berghei - physiology | Humans | Imidazoles - chemistry | Plasmodium - physiology | Piperazines - chemistry | Plasmodium falciparum - drug effects | Plasmodium - growth & development | Imidazoles - therapeutic use | Plasmodium falciparum - physiology | Antimalarials - pharmacokinetics | Antimalarials - therapeutic use | Imidazoles - pharmacology | Piperazines - therapeutic use | Random Allocation | Piperazines - pharmacology | Plasmodium berghei - cytology | Small Molecule Libraries | Malaria - parasitology | Cell Line, Tumor | Plasmodium berghei - growth & development | Mice | Mice, Inbred BALB C | Liver - parasitology | Erythrocytes - parasitology | Plasmodium berghei - drug effects | Plasmodium - cytology | Plasmodium falciparum - cytology | Plasmodium - drug effects | Imidazoles - pharmacokinetics | Plasmodium yoelii - growth & development | Protozoan Proteins - genetics | Sporozoites - growth & development | Protozoan Proteins - metabolism | Plasmodium yoelii - drug effects | Protozoan Proteins - chemistry | Molecular Structure | Piperazines - pharmacokinetics | Drug Evaluation, Preclinical | Sporozoites - drug effects | Drug Resistance | Plasmodium yoelii - physiology | Plasmodium yoelii - cytology | Drug Discovery | Antimalarials - pharmacology | Malaria - prevention & control | Animals | Antimalarials - chemistry | Polymorphism, Single Nucleotide | Malaria - drug therapy | Plasmodium falciparum - growth & development | Pharmaceutical research | Plasmodium | Care and treatment | Analysis | Research | Drug therapy
Journal Article
Journal of the American Geriatrics Society, ISSN 0002-8614, 10/2018, Volume 66, Issue 10, pp. 1927 - 1933
Objectives To explore whether baseline scores on the Mobility Assessment Tool—short form (MAT‐sf), a brief, animated, computer‐based means of assessing... 
hospitalization | mobility | physical function | MORTALITY | OLDER-ADULTS | PERFORMANCE | RANDOMIZED CLINICAL-TRIAL | RISK | CARE | MAJOR MOBILITY DISABILITY | GERIATRICS & GERONTOLOGY | READMISSION | ACUTE MEDICAL ILLNESS | GERONTOLOGY | BENEFICIARIES | Drugs | Prescribing | Medical research | Comorbidity | Analysis | Medicine, Experimental | Aged | Mobility | Cognition | Lifestyles | Hospitalization | Older people
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2013, Volume 56, Issue 14, pp. 5675 - 5690
Journal Article
Psychiatry Research, ISSN 0165-1781, 2012, Volume 199, Issue 3, pp. 220 - 227
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2015, Volume 59, Issue 10, pp. 6385 - 6394
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2017, Volume 60, Issue 24, pp. 9960 - 9973
The farnesoid X receptor (FXR) is a nuclear receptor that acts as a master regulator of bile acid metabolism and signaling. Activation of FXR inhibits bile... 
ITCH | CHEMISTRY, MEDICINAL | OBETICHOLIC ACID | SERIES | METABOLISM | PRIMARY BILIARY CHOLANGITIS | RECEPTOR FXR | FAMILIAL INTRAHEPATIC CHOLESTASIS
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2016, Volume 59, Issue 14, pp. 6671 - 6689
Over the past decade, first and second generation EGFR inhibitors have significantly improved outcomes for lung cancer patients with activating mutations in... 
GROWTH-FACTOR RECEPTOR | IRREVERSIBLE INHIBITORS | IN-VITRO | GEFITINIB | CHEMISTRY, MEDICINAL | METHIONINE MUTANT | BIOLOGICAL EVALUATION | TYROSINE KINASE INHIBITOR | DRUG-RESISTANCE | MUTATIONS | THREONINE | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Rats, Wistar | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Crystallography, X-Ray | Lung Neoplasms - pathology | Male | Structure-Activity Relationship | Benzimidazoles - chemistry | Nicotine - pharmacology | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Protein Kinase Inhibitors - chemical synthesis | Lung Neoplasms - enzymology | Benzimidazoles - chemical synthesis | Models, Molecular | Rats | Antineoplastic Agents - chemistry | Drug Discovery | Animals | Nicotine - chemical synthesis | Mice, Nude | Nicotine - analogs & derivatives | Nicotine - chemistry | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Mutation | Neoplasms, Experimental - drug therapy | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Journal of the American Geriatrics Society, ISSN 0002-8614, 10/2018, Volume 66, Issue 10, pp. 1927 - 1933
Journal Article
Journal Article