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1. Full Text Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
by Wu, Xifeng and Zhang, Qing and Doheny, Kimberly and Amos, Christopher I and Vijayakrishnan, Jayaram and Gorlov, Ivan P and Eisen, Timothy and Houlston, Richard S and Tsai, Ya-Yu and Gu, Xiangjun and Shete, Sanjay and Dong, Qiong and Broderick, Peter and Matakidou, Athena and Chen, Wei Vivien and Gu, Jian and Wang, Yufei and Mills, Gordon and Sullivan, Kate and Spitz, Margaret R
Nature Genetics, ISSN 1061-4036, 05/2008, Volume 40, Issue 5, pp. 616 - 622
To identify risk variants for lung cancer, we conducted a multistage genome-wide association study. In the discovery phase, we analyzed 315,450 tagging SNPs in... 
POPULATION | CELLS | RETINOBLASTOMA | RELATIVES | MAPS | GENETICS & HEREDITY | RISK | EXPRESSION | Haplotypes | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Genetic Testing | Humans | Middle Aged | Male | Chromosomes, Human, Pair 15 - genetics | Nerve Tissue Proteins - genetics | Cysteine Endopeptidases - genetics | Female | Aged | Polymorphism, Single Nucleotide | Genome, Human | Receptors, Nicotinic - genetics | Genetic Linkage | Lung cancer | Causes of | Disease susceptibility | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Identification and classification | Studies | Genomics | Genetic research | Risk | Gene loci | Cigarettes | Smoking
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2. Full Text Factors associated with favorable survival outcomes for Asians with hepatocellular carcinoma: A sequential matching cohort study
by Wang, ZS and Gu, XJ and Thrift, AP
PLOS ONE, ISSN 1932-6203, 04/2019, Volume 14, Issue 4, p. e0214721
Background Overall 5-year survival rates for patients diagnosed with hepatocellular carcinoma (HCC) are poor, but vary by race/ethnicity. We undertook a... 
UNITED-STATES | IMPACT | FATTY LIVER-DISEASE | STAGE | MULTIDISCIPLINARY SCIENCES | RACE | RACIAL/ETHNIC DISPARITIES | RACIAL DISPARITIES | SORAFENIB | SOCIOECONOMIC-STATUS | MARITAL-STATUS | Hepatoma | Comparative analysis | Comorbidity | Mortality | Patient outcomes | Asians | Health care | Demography | Transplants & implants | Identification methods | Hepatocellular carcinoma | Medical diagnosis | Epidemiology | Cancer therapies | Data bases | Matching | Confidence intervals | Liver cancer | Hepatitis | Demographics | Surgery | Race | Population | Liver diseases | Hazards | Minority & ethnic groups | Patients | Survival | Medicine | Marital status | Statistical models | Surveillance | Government programs | Socioeconomic factors | Medical prognosis | Internet
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3. Full Text Common 5p15.33 and 6p21.33 variants influence lung cancer risk
by Amos, Christopher I and Wu, Xifeng and Vijayakrishnan, Jayaram and Houlston, Richard S and Eisen, Timothy and Dong, Qiong and Spitz, Margaret R and Chen, Wei Vivien and Gu, Xiangjun and Broderick, Peter and Matakidou, Athena and Webb, Emily and Qureshi, Mobshra and Wang, Yufei
Nature Genetics, ISSN 1061-4036, 12/2008, Volume 40, Issue 12, pp. 1407 - 1409
We conducted a genome-wide association (GWA) study of lung cancer comparing 511,919 SNP genotypes in 1,952 cases and 1,438 controls. The most significant... 
MICROSATELLITE INSTABILITY | GENETICS & HEREDITY | SUSCEPTIBILITY LOCUS | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Polymorphism, Single Nucleotide | Case-Control Studies | Chromosomes, Human, Pair 6 - genetics | Chromosomes, Human, Pair 5 - genetics | Chromosome mapping | Lung cancer | Genetic aspects | Research | Single nucleotide polymorphisms | Methods | Risk factors | Confidence intervals | Medical research | Genotype & phenotype | Inflation | Sample size | Quality control | Data collection | Genetics | Risk | Apoptosis
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4. Full Text Mo1496 – Trends in Cure Rates Among Medicare Insured Patients with Hepatocellular Carcinoma: A Population-Based Study
by Thrift, Aaron P and Gu, Xiangjun and El-Serag, Hashem B
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-768 - S-768
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5. Full Text Genome-wide association study identifies five susceptibility loci for glioma
by Shete, Sanjay and Hosking, Fay J and Robertson, Lindsay B and Dobbins, Sara E and Sanson, Marc and Malmer, Beatrice and Simon, Matthias and Marie, Yannick and Boisselier, Blandine and Delattre, Jean-Yves and Hoang-Xuan, Khe and Hallani, Soufiane El and Idbaih, Ahmed and Zelenika, Diana and Andersson, Ulrika and Henriksson, Roger and Bergenheim, A. Tommy and Feychting, Maria and Lönn, Stefan and Ahlbom, Anders and Schramm, Johannes and Linnebank, Michael and Hemminki, Kari and Kumar, Rajiv and Hepworth, Sarah J and Price, Amy and Armstrong, Georgina and Liu, Yanhong and Gu, Xiangjun and Yu, Robert and Lau, Ching and Schoemaker, Minouk and Muir, Kenneth and Swerdlow, Anthony and Lathrop, Mark and Bondy, Melissa and Houlston, Richard S and Medicinska fakulteten and Institutionen för farmakologi och klinisk neurovetenskap and Neurokirurgi and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Nature Genetics, ISSN 1061-4036, 08/2009, Volume 41, Issue 8, pp. 899 - 904
To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association studies by genotyping 550K tagging SNPs in a total of 1,878... 
BREAST-CANCER | POPULATION | 8Q24 | GLIOBLASTOMA | RETINOIC ACID | GENETICS & HEREDITY | NERVOUS-SYSTEM TUMORS | GENE-EXPRESSION | BIRTH-WEIGHT | RISK | DELETION | Glioma - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Humans | Alleles | Linkage Disequilibrium - genetics | Polymorphism, Single Nucleotide - genetics | Quantitative trait loci | Care and treatment | Prognosis | Gliomas | Disease susceptibility | Genetic aspects | Research | Diagnosis | Confidence intervals | Genetic markers | Inflation | Genomics | Quality control | Data collection | Gene loci | Cancer | Apoptosis
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6. Full Text Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
by Hirschfield, Gideon M and Liu, Xiangdong and Xu, Chun and Lu, Yan and Lu, Yue and Xie, Gang and Gu, Xiangjun and Walker, Erin J and Jing, Kaiyan and Juran, Brian D and Mason, Andrew L and Myers, Robert P and Peltekian, Kevork M and Ghent, Cameron N and Coltescu, Catalina and Atkinson, Elizabeth J and Heathcote, E. Jenny and Lazaridis, Konstantinos N and Amos, Christopher I and Siminovitch, Katherine A
The New England Journal of Medicine, ISSN 0028-4793, 06/2009, Volume 360, Issue 24, pp. 2544 - 2555
A genomewide association analysis of patients with primary biliary cirrhosis suggests that variation in interleukin-12 signaling may confer a risk of disease.... 
ANTIMITOCHONDRIAL ANTIBODIES | RHEUMATOID-ARTHRITIS | POPULATION | MEDICINE, GENERAL & INTERNAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | GENE | ULCERATIVE-COLITIS | DISEASE | LARGE-SCALE | SUSCEPTIBILITY LOCUS | GENOME-WIDE ASSOCIATION | Genes, MHC Class II | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Genotype | Interleukin-12 Subunit p35 - genetics | HLA Antigens - genetics | Liver Cirrhosis, Biliary - genetics | Interleukin-23 - genetics | HLA-DQ Antigens - genetics | Interleukin-12 Receptor beta 2 Subunit - genetics | Receptors, Interleukin-12 - genetics | Polymorphism, Single Nucleotide | HLA-DQ beta-Chains | Transplants & implants | Autoimmune diseases | Lymphocytes | Liver cirrhosis | Quality control
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7. Full Text 1356-P: Comparison of Serum Adipokines and Anthropometric Measures in Children with Type 1 Diabetes (T1D) and Obesity
by REDONDO, MARIA JOSE and GU, XIANGJUN and SISLEY, STEPHANIE and TOSUR, MUSTAFA and SILLER, ALEJANDRO F and BONDY, MELISSA and DEVARAJ, SRIDEVI
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1356
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8. Full Text Green Synthesis of Fluorescent Carbon Dots for Selective Detection of Tartrazine in Food Samples
by Xu, Hua and Yang, Xiupei and Li, Gu and Zhao, Chuan and Liao, Xiangjun
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 08/2015, Volume 63, Issue 30, pp. 6709 - 6716
A simple, economical, and green method for the preparation of water-soluble, high-fluorescent carbon quantum dots (C-dots) has been developed via hydrothermal... 
fluorescence quench | tartrazine | aloe | carbon quantum dots | DYES | FOOD SCIENCE & TECHNOLOGY | GRAPHENE | PERFORMANCE LIQUID-CHROMATOGRAPHY | PONCEAU 4R | NANOPARTICLES | AGRICULTURE, MULTIDISCIPLINARY | ELECTROCHEMICAL SENSOR | FABRICATION | CHEMISTRY, APPLIED | BOVINE SERUM-ALBUMIN | SUNSET YELLOW | COLORANTS | Green Chemistry Technology | Aloe - chemistry | Food Analysis - methods | Fluorescence | Honey - analysis | Food Coloring Agents - chemistry | Carbon - chemistry | Bread - analysis | Particle Size | Quantum Dots - chemistry | Candy - analysis | Food Analysis - instrumentation | Tartrazine - chemistry | Index Medicus
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9. Full Text Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations
by Ganesh, Santhi K and Chasman, Daniel I and Larson, Martin G and Guo, Xiuqing and Verwoert, Germain and Bis, Joshua C and Gu, Xiangjun and Smith, Albert V and Yang, Min-Lee and Zhang, He and Zhang, Feng and Zhang, Yan and Ehret, Georg and Rose, Lynda M and Hwang, Shih-Jen and Papanicolau, George J and Sijbrands, Eric J and Rice, Kenneth and Eiriksdottir, Gudny and Pihur, Vasyl and Ridker, Paul M and Vasan, Ramachandran S and Newton-Cheh, Christopher and Johnson, Andrew D and Johnson, Toby and Gateva, Vesela and Tobin, Martin D and Bochud, Murielle and Coin, Lachlan and Najjar, Samer S and Zhao, Jing Hua and Heath, Simon C and Eyheramendy, Susana and Papadakis, Konstantinos and Voight, Benjamin F and Scott, Laura J and Farrall, Martin and Tanaka, Toshiko and Wallace, Chris and Chambers, John C and Khaw, Kay-Tee and Nilsson, Peter and van der Harst, Pim and Polidoro, Silvia and Grobbee, Diederick E and Onland-Moret, N. Charlotte and Bots, Michiel L and Wain, Louise V and Elliott, Katherine S and Elliott, Paul and Teumer, Alexander and Luan, Jian’an and Lucas, Gavin and Kuusisto, Johanna and Burton, Paul R and Hadley, David and McArdle, Wendy L and Brown, Morris and Dominiczak, Anna and Newhouse, Stephen J and Samani, Nilesh J and Webster, John and Zeggini, Eleftheria and Beckmann, Jacques S and Bergmann, Sven and Lim, Noha and Song, Kijoung and Vollenweider, Peter and Waeber, Gerard and Waterworth, Dawn M and Yuan, Xin and Groop, Leif and Orho-Melander, Marju and Allione, Alessandra and Di Gregorio, Alessandra and Guarrera, Simonetta and Panico, Salvatore and Ricceri, Fulvio and Romanazzi, Valeria and Sacerdote, Carlotta and Vineis, Paolo and Barroso, Inês and Sandhu, Manjinder S and Luben, Robert N and Crawford, Gabriel J and Jousilahti, Pekka and Perola, Markus and Boehnke, Michael and Bonnycastle, Lori L and Collins, Francis S and Jackson, Anne U and Mohlke, Karen L and Stringham, Heather M and Valle, Timo T and Willer, Cristen J and Willer, Cristen J and Bergman, Richard N and Morken, Mario A and Döring, Angela and Gieger, Christian and ... and Global Blood Pressure Genetics Con and Global Blood Pressure Genetics Consortium
The American Journal of Human Genetics, ISSN 0002-9297, 07/2014, Volume 95, Issue 1, pp. 49 - 65
Blood pressure (BP) is a heritable, quantitative trait with intraindividual variability and susceptibility to measurement error. Genetic studies of BP... 
HEART | VARIABILITY | TRACKING | GENETICS & HEREDITY | CARDIOVASCULAR-DISEASE | RISK | EXPRESSION | CHILDHOOD | GENOME-WIDE ASSOCIATION | GROWTH-FACTOR-I | REVEALS | Genome-Wide Association Study | Phenotype | Blood Pressure - genetics | Humans | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Longitudinal Studies | Quantitative trait loci | Genetic research | Blood pressure | Genetic aspects | Research
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10. Full Text Inhibition of TRPC6 signal pathway alleviates podocyte injury induced by TGF-β1
by Huang, Haiting and Lin, Xu and You, Yanwu and Tang, Chunrong and Gu, Xiangjun and Huang, Meiying and Qin, Youling and Tan, Junhua and Huang, Feifan
Cellular Physiology and Biochemistry, ISSN 1015-8987, 2017, Volume 41, Issue 1, pp. 163 - 172
Transforming growth factor beta 1 (TGF-β1) plays a critical role in the pathogenesis of glomerulosclerosis. The purpose of this study was to examine the... 
Podocytes | TGF-β1 | Caspase 9 | Nephrin | TRPC6 | Desmin | Caspase 9 - genetics | Caspase 9 - metabolism | Male | RNA, Messenger - metabolism | Gene Knockdown Techniques | Plasmids - genetics | Membrane Proteins - metabolism | TRPC Cation Channels - genetics | Transforming Growth Factor beta1 - pharmacology | Disease Models, Animal | Diabetic Nephropathies - pathology | Podocytes - metabolism | Membrane Proteins - genetics | Diabetic Nephropathies - metabolism | Cells, Cultured | Diabetic Nephropathies - chemically induced | Rats | Plasmids - metabolism | Rats, Sprague-Dawley | TRPC Cation Channels - antagonists & inhibitors | Doxorubicin - toxicity | Podocytes - cytology | Up-Regulation - drug effects | Animals | Podocytes - drug effects | Signal Transduction - drug effects | Desmin - metabolism | TRPC Cation Channels - metabolism | Desmin - genetics | Mice | Proteins | Membranes | Kidneys | Cytokines | Rodents | Protein expression | Gene expression | Kinases | Growth factors | Apoptosis
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11. Full Text Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
by McKay, J.D and Hung, R.J and Han, Y and Zong, X and Carreras-Torres, R and Christiani, D.C and Caporaso, N and Johansson, M and Li, Y and Byun, J.Y and Dunning, A and Pooley, K.A and Qian, D.C and Liu, G and Bojesen, S.E and Wu, X and Marchand, L. le and Albanes, D and Bickeböller, H and Alich, M.C and Bush, W.S and Tardon, A and Rennert, G and Teare, M.D and Field, J.K and Kiemeney, L.A and Lazarus, P and Haugen, A and Schabath, M.B and Anew, A.S and Shen, H and Hong, Y.C and Yuan, J.M and Bertazzi, P.A and Pesatori, A.C and Ye, Y and Diao, N and Su, L and Zhang, R and Brhane, Y and Leighl, N and Johansen, J.S and Mellemgaard, A and Saliba, W and Haiman, C.A and Wilkens, L.R and Fernandez-Somoano, A and Fernandez-Tardon, G and Heijden, H.F.M. van der and Kim, J.H and Hu, Z and Davies, M and Brunnström, H and Manjer, J and Melander, O and Muller, D and Overvad, K and Trichopoulou, A and Tumino, R and Doherty, J.A and Barnett, M.P and Chen, C and Goodman, G.E and Cox, A and Taylor, F and Woll, P.J and Brüske, I and Wichmann, H.E and Manz, J and Muley, T.R and Risch, A and Rosenberger, A and Grankvist, K and Shepherd, F.A and Tsao, M.S and Haura, E.B and Bolca, C and Holcatova, I and Janout, V and Kontic, M and Lissowska, J and Mukeria, A and Ognjanovic, S and Orlowski, T.M and Scelo, G and Swiatkowska, B and Zaridze, D and Bakke, P and Skaug, V and Zienolddiny, S and Duell, E.J and Butler, L.M and Koh, W.P and Gao, Y.T and Houlston, R.S and McLaughlin, J and Stevens, V.L and Joubert, P and Lamontagne, M and Nickle, D.C and ... and SpiroMeta Consortium and Medicinska fakulteten and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1126 - 1132
Although several lung cancer susceptibility loci have been identified, much of the heritability for lung cancer remains unexplained. Here 14,803 cases and... 
IMPUTATION | METAANALYSIS | CROHNS-DISEASE | VARIANTS | GENETICS & HEREDITY | ARCHITECTURE | RISK | COMPONENT | GENOME-WIDE ASSOCIATION | TELOMERE LENGTH | Lung Neoplasms - genetics | Lung Neoplasms - ethnology | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Adenocarcinoma of Lung | Humans | Middle Aged | Family Health | Genotype | Male | Chromosome Mapping | Telomere Homeostasis - genetics | Lung Neoplasms - epidemiology | Smoking - epidemiology | Adult | Female | Adenocarcinoma - genetics | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Adenocarcinoma | Genealogy | Disease | Genes | Lung cancer | Association analysis | Exploration | Genomes | Gene expression | Loci | Quantitative trait loci | Studies | Consortia | Heterogeneity | Etiology | Chronic obstructive pulmonary disease | Heritability | Cancer | Smoking | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Genome-wide association studies | Medical and Health Sciences | Medicin och hälsovetenskap | Transcriptomics | Medicinska och farmaceutiska grundvetenskaper
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12. Full Text Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
by Soler Artigas, María and Loth, Daan W and Wain, Louise V and Gharib, Sina A and Obeidat, Ma'en and Tang, Wenbo and Zhai, Guangju and Zhao, Jing Hua and Smith, Albert Vernon and Huffman, Jennifer E and Albrecht, Eva and Jackson, Catherine M and Evans, David M and Cadby, Gemma and Fornage, Myriam and Manichaikul, Ani and Lopez, Lorna M and Johnson, Toby and Alich, Melinda C and Aspelund, Thor and Barroso, Inês and Campbell, Harry and Cassano, Patricia A and Couper, David J and Eiriksdottir, Gudny and Franceschini, Nora and Garcia, Melissa and Gieger, Christian and Gislason, Gauti Kjartan and Grkovic, Ivica and Hammond, Christopher J and Hancock, Dana B and Harris, Tamara B and Ramasamy, Adaikalavan and Heckbert, Susan R and Heliövaara, Markku and Homuth, Georg and Hysi, Pirro G and James, Alan L and Jankovic, Stipan and Joubert, Bonnie R and Karrasch, Stefan and Klopp, Norman and Koch, Beate and Kritchevsky, Stephen B and Launer, Lenore J and Liu, Yongmei and Loehr, Laura R and Lohman, Kurt and Loos, Ruth J F and Lumley, Thomas and Al Balushi, Khalid A and Ang, Wei Q and Barr, R Graham and Beilby, John and Blakey, John D and Boban, Mladen and Boraska, Vesna and Brisman, Jonas and Britton, John R and Brusselle, Guy G and Cooper, Cyrus and Curjuric, Ivan and Dahgam, Santosh and Deary, Ian J and Ebrahim, Shah and Eijgelsheim, Mark and Francks, Clyde and Gaysina, Darya and Granell, Raquel and Gu, Xiangjun and Hankinson, John L and Hardy, Rebecca and Harris, Sarah E and Henderson, John and Henry, Amanda and Hingorani, Aroon D and Hofman, Albert and Holt, Patrick G and Hui, Jennie and Hunter, Michael L and Imboden, Medea and Jameson, Karen A and Kerr, Shona M and Kolcic, Ivana and Kronenberg, Florian and Liu, Jason Z and Marchini, Jonathan and McKeever, Tricia and Morris, Anew D and Olin, Anna-Carin and Porteous, David J and Postma, Dirkje S and Rich, Stephen S and Ring, Susan M and Rivadeneira, Fernando and Rochat, Thierry and Sayer, Avan Aihie and Sayers, Ian and Sly, Peter D and ... and GIANT Consortium and Int Lung Canc Consortium and International Lung Cancer Consortium and GIANT consortium and The International Lung Cancer Consortium and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institute of Medicine, Department of Public Health and Community Medicine
Nature Genetics, ISSN 1061-4036, 11/2011, Volume 43, Issue 11, pp. 1082 - 1090
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide... 
GENETIC-VARIATION | POPULATION | OBSTRUCTIVE PULMONARY-DISEASE | METAANALYSIS | PROTEIN | POLYMORPHISMS | VARIANTS | GENETICS & HEREDITY | RISK | EXPRESSION | BLOOD-PRESSURE | Genome-Wide Association Study | Humans | European Continental Ancestry Group | Pulmonary Disease, Chronic Obstructive - physiopathology | Respiratory Function Tests | Child | Pulmonary Disease, Chronic Obstructive - genetics | Studies | Airway management | Genealogy | Heart attacks | Lungs | Smooth muscle | Genomes | Muscular system | Meta-analysis | Medicinsk genetik | Medical Genetics | Lungmedicin och allergi | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Respiratory Medicine and Allergy | Public Health, Global Health, Social Medicine and Epidemiology
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