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Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2013, Volume 28, Issue 4, pp. 899 - 911
Fibroblast growth factor 23 (FGF23) is a circulating factor secreted by osteocytes that is essential for phosphate homeostasis. In kidney proximal tubular... 
TARGETED THERAPY | FIBROBLAST GROWTH FACTOR RECEPTOR | PHOSPHATE HOMEOSTASIS | HYPOPHOSPHATEMIC RICKETS | FGF23 | phosphate homeostasis | targeted therapy | hypophosphatemic rickets | fibroblast growth factor receptor | KLOTHO | VITAMIN-D METABOLISM | X-LINKED HYPOPHOSPHATEMIA | DMP1 | PATHOGENIC ROLE | HYP MICE | ENDOCRINOLOGY & METABOLISM | MINERAL METABOLISM | BONE | EXPRESSION | Growth Plate - pathology | Femur - pathology | Rickets, Hypophosphatemic - pathology | Extracellular Matrix Proteins - deficiency | Body Weight - drug effects | Vitamin D - biosynthesis | Fibroblast Growth Factors - metabolism | Kidney - metabolism | Growth Plate - drug effects | Rickets, Hypophosphatemic - metabolism | Homeostasis - drug effects | Minerals - metabolism | Extracellular Matrix Proteins - metabolism | Tail - anatomy & histology | Kidney - drug effects | Bone Development - drug effects | Mice, Inbred C57BL | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Phenylurea Compounds - therapeutic use | Femur - drug effects | Ions | Rickets, Hypophosphatemic - drug therapy | Pyrimidines - pharmacology | Animals | Signal Transduction - drug effects | Pyrimidines - therapeutic use | Receptors, Fibroblast Growth Factor - metabolism | Vitamin D - analogs & derivatives | Phenylurea Compounds - pharmacology | Phosphates | Rickets | Vitamin D | Heterocyclic compounds | Analysis | Calcifediol | Fibroblast growth factors | Alfacalcidol | Index Medicus
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2011, Volume 54, Issue 20, pp. 7066 - 7083
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 10, pp. e77652 - e77652
Malignant rhabdoid tumors (MRTs) are aggressive pediatric cancers arising in brain, kidney and soft tissues, which are characterized by loss of the tumor... 
SYNOVIAL SARCOMA | FAMILIAL SCHWANNOMATOSIS | SOFT-TISSUE SARCOMAS | SWI/SNF COMPLEX | CHROMATIN-REMODELING COMPLEX | SUPPRESSOR GENE | MULTIDISCIPLINARY SCIENCES | CELL-CYCLE ARREST | SMARCB1/INI1 PROTEIN | ONCOGENIC TRANSFORMATION | INI1 | Cell Proliferation | Chromosomal Proteins, Non-Histone - metabolism | Humans | Carcinogenesis - genetics | Chromatin Assembly and Disassembly - genetics | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Carcinogenesis - metabolism | Promoter Regions, Genetic - genetics | Chromosomal Proteins, Non-Histone - genetics | DNA-Binding Proteins - metabolism | SMARCB1 Protein | Transcription Factors - metabolism | Animals | Rhabdoid Tumor - genetics | Receptors, Fibroblast Growth Factor - metabolism | HEK293 Cells | Receptors, Fibroblast Growth Factor - genetics | Cell Line, Tumor | Mice | Rhabdoid Tumor - metabolism | Fibroblasts - metabolism | Chemotherapy | Chromatin | Genes | Fibroblast growth factors | Gene expression | Health aspects | Tumors | Cancer | Brain | Pediatrics | Fibroblast growth factor | Biomedical research | Syngeneic grafts | Amino acids | Genomes | Remodeling | Kinases | Tissues | Receptors | Cell cycle | Fibroblasts | Growth factors | Fibroblast growth factor receptor 2 | Deoxyribonucleic acid--DNA | Kidneys | Pharmacology | siRNA | Growth factor receptors | Chromatin remodeling | Soft tissues | Signaling | Cell lines | Tumor suppressor genes | Mutation | Receptor mechanisms | Aberration | Kidney transplantation | Fibroblast growth factor receptors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Cancer Discovery, ISSN 2159-8274, 12/2012, Volume 2, Issue 12, pp. 1118 - 1133
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2018, Volume 28, Issue 20, pp. 3404 - 3408
Journal Article
ChemMedChem, ISSN 1860-7179, 07/2019, Volume 14, Issue 14, pp. 1304 - 1304
The Front Cover shows a crystal of HdmX in a drop of mother liquor and the X‐ray structures of the clinical trial compounds NVP‐CGM097 and NVP‐HDM201 bound to... 
protein–protein interactions | X-ray crystallography | Hdm2 | HdmX | anticancer agents | p53
Journal Article
Cancer Discovery, ISSN 2159-8274, 10/2012, Volume 2, Issue 10, pp. 948 - 959
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2016, Volume 26, Issue 8, pp. 2057 - 2064
Journal Article