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1. Full Text Mechanisms of Hippo pathway regulation
by Meng, Zhipeng and Moroishi, Toshiro and Guan, Kun-Liang
Genes & development, ISSN 0890-9369, 01/2016, Volume 30, Issue 1, pp. 1 - 17
MAP4K | YAP | TEAD | TAZ | LATS | MST | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Animals | Signal Transduction | Humans | Drosophila melanogaster - enzymology | Gene Expression Regulation, Enzymologic - physiology | Transcription Factors - genetics | Protein-Serine-Threonine Kinases - metabolism | Drosophila | Analysis | Genetic aspects | Research | Bacterial genetics | Phosphotransferases | DNA-ligand interactions | Index Medicus | Review
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2. Full Text MTOR: A pharmacologic target for autophagy regulation
by Kim, Young Chul and Guan, Kun-Liang
The Journal of clinical investigation, ISSN 0021-9738, 01/2015, Volume 125, Issue 1, pp. 25 - 32
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | TOR Serine-Threonine Kinases - antagonists & inhibitors | Animals | Humans | Metformin - pharmacology | TOR Serine-Threonine Kinases - physiology | Sirolimus - pharmacology | Autophagy - drug effects | Physiological aspects | Autophagy (Cytology) | Cellular signal transduction | Research | Protein kinases | Mutation | Kinases | Neurodegeneration | Metabolic disorders | Index Medicus | Abridged Index Medicus | Review
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3. Full Text mTOR as a central hub of nutrient signalling and cell growth
by Kim, Joungmok and Guan, Kun-Liang
Nature cell biology, ISSN 1465-7392, 01/2019, Volume 21, Issue 1, pp. 63 - 71
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Nutrients - physiology | TOR Serine-Threonine Kinases - metabolism | Models, Biological | Humans | Amino Acids - physiology | Cell Proliferation - physiology | Cell Cycle - physiology | Signal Transduction - physiology | Cell metabolism | Amino acids | Cellular signal transduction | Research | Protein kinases | Proteins | TOR protein | Signaling | Cell growth | Protein kinase | Therapeutic applications | Growth regulators | Chemoreception | Rapamycin | Metabolism | Kinases | Index Medicus
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4. Full Text The emerging roles of YAP and TAZ in cancer
by Moroishi, Toshiro and Hansen, Carsten Gram and Guan, Kun-Liang
Nature reviews. Cancer, ISSN 1474-175X, 01/2015, Volume 15, Issue 2, pp. 73 - 79
Life Sciences & Biomedicine | Oncology | Science & Technology | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Cytoskeletal Proteins - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | GTP-Binding Protein alpha Subunits - genetics | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Neoplasms - genetics | Wnt Signaling Pathway - genetics | Cell Transformation, Neoplastic - genetics | GTP-Binding Protein alpha Subunits, Gq-G11 | Adaptor Proteins, Signal Transducing - genetics | MicroRNAs - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Apoptosis | Physiological aspects | Cellular proteins | Development and progression | Research | Cancer | Index Medicus
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5. Full Text The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
by Zhao, Bin and Tumaneng, Karen and Guan, Kun-Liang
Nature cell biology, ISSN 1465-7392, 08/2011, Volume 13, Issue 8, pp. 877 - 883
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Humans | Drosophila - cytology | Organ Size - physiology | Stem Cells - cytology | Regeneration - physiology | Drosophila - physiology | Drosophila Proteins - physiology | Animals | Cell Adhesion - physiology | Models, Biological | Cell Polarity - physiology | Stem Cells - physiology | Intercellular Junctions - physiology | Mice | Intracellular Signaling Peptides and Proteins - physiology | Physiological aspects | Cellular signal transduction | Research | Regeneration (Biology) | Stem cells | Index Medicus
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6. Full Text Autophagy regulation by nutrient signaling
by Ryan C Russell Hai-Xin Yuan Kun-Liang Guan
Cell research, ISSN 1001-0602, 2014, Volume 24, Issue 1, pp. 42 - 57
营养素 | 细胞反应 | 蛋白激酶 | 调节能力 | 协同调控 | 代谢过程 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Multiprotein Complexes - metabolism | AMP-Activated Protein Kinases - metabolism | Animals | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Homeostasis - physiology | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagy - physiology | Mechanistic Target of Rapamycin Complex 1 | Index Medicus | autophagy | amino acids | AMPK | ULK1 | Review | VPS34 | oxygen | mTORC1
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