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by Elks, Cathy and Perry, John and Sulem, Patrick and Chasman, Daniel and Franceschini, Nora and He, Chunyan and Lunetta, Kathryn and Visser, Jenny and Byrne, Enda and Cousminer, Diana and Gudbjartsson, Daniel and Esko, Tõnu and Feenstra, Bjarke and Hottenga, Jouke Jan and Koller, Daniel and Kutalik, Zoltán and Lin, Peng and Mangino, Massimo and Marongiu, Mara and McArdle, Patrick and Smith, Albert Vernon and Stolk, Lisette and Wingerden, Sophie and Zhao, Jing Hua and Albrecht, Eva and Corre, Tanguy and Ingelsson, Erik and Hayward, Caroline and Magnusson, Patrik and Ulivi, Shelia and Warrington, Nicole and Zgaga, Lina and Alavere, Helene and Amin, Najaf and Aspelund, Thor and Bandinelli, Stefania and Barroso, Inês and Berenson, Gerald and Bergmann, Sven and Blackburn, Hannah and Boerwinkle, Eric and Buring, Julie and Busonero, F and Campbell, Harry and Chanock, Stephen and Chen, Wei and Cornelis, Marilyn and Couper, David and Coviello, Anea and Adamo, Pio and Faire, Ulf and Geus, Eco and Deloukas, Panagiotis and Döring, Angela and Easton, Douglas and Eiriksdottir, Gudny and Emilsson, Valur and Eriksson, Johan and Ferrucci, Luigi and Folsom, Aaron and Foroud, Tatiana and Garcia, Melissa and Gasparini, Paolo and Geller, Frank and Gieger, Christian and Gudnason, Vilmundur and Hall, Alistair and Hankinson, Susan and Ferreli, Liana and Heath, Anew and Hernandez, Dena and Hofman, Albert and Hu, Frank and Illig, Thomas and Järvelin, M.R and Johnson, Anew and Karasik, David and Khaw, Kay-Tee and Kiel, Douglas and Kilpelänen, Tuomas and Kolcic, Ivana and Kraft, Peter and Launer, Lenore and Laven, Joop and Li, Shengxu and Liu, Jianjun and Levy, Daniel and Martin, Nicholas and Melbye, Mads and Mooser, Vincent and Murray, Jeffrey and Nalls, Michael and Navarro, Pau and Nelis, Mari and Ness, Anew and Northstone, Kate and Oostra, Ben and Peacock, Munro and Palmer, Cameron and Palotie, Aarno and ... and GIANT Consortium and The GIANT Consortium
Nature genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1077 - 1085
Journal Article
by Gusarova, Viktoria and O’Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
by Liu, Mengzhen and Jiang, Yu and Wedow, Robbee and Li, Yue and Brazel, David M and Chen, Fang and Datta, Gargi and Davila-Velderrain, Jose and McGuire, Daniel and Tian, Chao and Zhan, Xiaowei and Choquet, Hélène and Docherty, Anna R and Faul, Jessica D and Foerster, Johanna R and Fritsche, Lars G and Gabrielsen, Maiken Elvestad and Gordon, Scott D and Haessler, Jeffrey and Hottenga, Jouke-Jan and Huang, Hongyan and Jang, Seon-Kyeong and Jansen, Philip R and Ling, Yueh and Mägi, Reedik and Matoba, Nana and McMahon, George and Mulas, Antonella and Orrù, Valeria and Palviainen, Teemu and Pandit, Anita and Reginsson, Gunnar W and Skogholt, Anne Heidi and Smith, Jennifer A and Taylor, Amy E and Turman, Constance and Willemsen, Gonneke and Young, Hannah and Young, Kendra A and Zajac, Gregory J. M and Zhao, Wei and Zhou, Wei and Bjornsdottir, Gyda and Boardman, Jason D and Boehnke, Michael and Boomsma, Dorret I and Chen, Chu and Cucca, Francesco and Davies, Gareth E and Eaton, Charles B and Ehringer, Marissa A and Esko, Tõnu and Fiorillo, Edoardo and Gillespie, Nathan A and Gudbjartsson, Daniel F and Haller, Toomas and Harris, Kathleen Mullan and Heath, Andrew C and Hewitt, John K and Hickie, Ian B and Hokanson, John E and Hopfer, Christian J and Hunter, David J and Iacono, William G and Johnson, Eric O and Kamatani, Yoichiro and Kardia, Sharon L. R and Keller, Matthew C and Kellis, Manolis and Kooperberg, Charles and Kraft, Peter and Krauter, Kenneth S and Laakso, Markku and Lind, Penelope A and Loukola, Anu and Lutz, Sharon M and Madden, Pamela A. F and Martin, Nicholas G and McGue, Matt and McQueen, Matthew B and Medland, Sarah E and Metspalu, Andres and Mohlke, Karen L and Nielsen, Jonas B and Okada, Yukinori and Peters, Ulrike and Polderman, Tinca J. C and Posthuma, Danielle and Reiner, Alexander P and Rice, John P and Rimm, Eric and Rose, Richard J and Runarsdottir, Valgerdur and Stallings, Michael C and Stančáková, Alena and Stefansson, Hreinn and Thai, Khanh K and Tindle, Hilary A and Tyrfingsson, Thorarinn and Wall, Tamara L and ... and 23andMe Research Team and HUNT All-In Psychiatry and HUNT All In Psychiat and 23 Me Res Team
Nature genetics, ISSN 1546-1718, 2019, Volume 51, Issue 2, pp. 237 - 244
Journal Article
by Lango Allen, Hana and Estrada, Karol and Lettre, Guillaume and Berndt, Sonja I and Weedon, Michael N and Rivadeneira, Fernando and Willer, Cristen J and Jackson, Anne U and Vedantam, Sailaja and Raychaudhuri, Soumya and Ferreira, Teresa and Wood, Andrew R and Weyant, Robert J and Segrè, Ayellet V and Speliotes, Elizabeth K and Wheeler, Eleanor and Soranzo, Nicole and Park, Ju-Hyun and Yang, Jian and Gudbjartsson, Daniel and Heard-Costa, Nancy L and Randall, Joshua C and Qi, Lu and Vernon Smith, Albert and Mägi, Reedik and Pastinen, Tomi and Liang, Liming and Heid, Iris M and Luan, Jian’an and Thorleifsson, Gudmar and Winkler, Thomas W and Goddard, Michael E and Sin Lo, Ken and Palmer, Cameron and Workalemahu, Tsegaselassie and Aulchenko, Yurii S and Johansson, Åsa and Carola Zillikens, M and Feitosa, Mary F and Esko, Tõnu and Johnson, Toby and Ketkar, Shamika and Kraft, Peter and Mangino, Massimo and Prokopenko, Inga and Absher, Devin and Albrecht, Eva and Ernst, Florian and Glazer, Nicole L and Hayward, Caroline and Hottenga, Jouke-Jan and Jacobs, Kevin B and Knowles, Joshua W and Kutalik, Zoltán and Monda, Keri L and Polasek, Ozren and Preuss, Michael and Rayner, Nigel W and Robertson, Neil R and Steinthorsdottir, Valgerdur and Tyrer, Jonathan P and Voight, Benjamin F and Wiklund, Fredrik and Xu, Jianfeng and Hua Zhao, Jing and Nyholt, Dale R and Pellikka, Niina and Perola, Markus and Perry, John R. B and Surakka, Ida and Tammesoo, Mari-Liis and Altmaier, Elizabeth L and Amin, Najaf and Aspelund, Thor and Bhangale, Tushar and Boucher, Gabrielle and Chasman, Daniel I and Chen, Constance and Coin, Lachlan and Cooper, Matthew N and Dixon, Anna L and Gibson, Quince and Grundberg, Elin and Hao, Ke and Juhani Junttila, M and Kaplan, Lee M and Kettunen, Johannes and König, Inke R and Kwan, Tony and Lawrence, Robert W and Levinson, Douglas F and Lorentzon, Mattias and McKnight, Barbara and Morris, Andrew P and Müller, Martina and Suh Ngwa, Julius and Purcell, Shaun and Rafelt, Suzanne and Salem, Rany M and Salvi, Erika and ... and Procardis Consortium and Göteborgs universitet and Institutionen för medicin, avdelningen för invärtesmedicin and Gothenburg University and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine
Nature (London), ISSN 1476-4687, 2010, Volume 467, Issue 7317, pp. 832 - 838
Journal Article
by Stacey, Simon N and Sulem, Patrick and Jonasdottir, Aslaug and Masson, Gisli and Gudmundsson, Julius and Gudbjartsson, Daniel F and Magnusson, Olafur T and Gudjonsson, Sigurjon A and Sigurgeirsson, Bardur and Thorisdottir, Kristin and Ragnarsson, Rafn and Benediktsdottir, Kristrun R and Nexø, Bjørn A and Tjønneland, Anne and Overvad, Kim and Rudnai, Peter and Gurzau, Eugene and Koppova, Kvetoslava and Hemminki, Kari and Corredera, Cristina and Fuentelsaz, Victoria and Grasa, Pilar and Navarrete, Sebastian and Fuertes, Fernando and García-Prats, Maria D and Sanambrosio, Enrique and Panadero, Angeles and De Juan, Ana and Garcia, Almudena and Rivera, Fernando and Planelles, Dolores and Soriano, Virtudes and Requena, Celia and Aben, Katja K and van Rossum, Michelle M and Cremers, Ruben G H M and van Oort, Inge M and van Spronsen, Dick-Johan and Schalken, Jack A and Peters, Wilbert H M and Helfand, Brian T and Donovan, Jenny L and Hamdy, Freddie C and Badescu, Daniel and Codreanu, Ovidiu and Jinga, Mariana and Csiki, Irma E and Constantinescu, Vali and Badea, Paula and Mates, Ioan N and Dinu, Daniela E and Constantin, Adrian and Mates, Dana and Kristjansdottir, Sjofn and Agnarsson, Bjarni A and Jonsson, Eirikur and Barkardottir, Rosa B and Einarsson, Gudmundur V and Sigurdsson, Fridbjorn and Moller, Pall H and Stefansson, Tryggvi and Valdimarsson, Trausti and Johannsson, Oskar T and Sigurdsson, Helgi and Jonsson, Thorvaldur and Jonasson, Jon G and Tryggvadottir, Laufey and Rice, Terri and Hansen, Helen M and Xiao, Yuanyuan and Lachance, Daniel H and O′Neill, Brian Patrick and Kosel, Matthew L and Decker, Paul A and Thorleifsson, Gudmar and Johannsdottir, Hrefna and Helgadottir, Hafdis T and Sigurdsson, Asgeir and Steinthorsdottir, Valgerdur and Lindblom, Annika and Sandler, Robert S and Keku, Temitope O and Banasik, Karina and Jørgensen, Torben and Witte, Daniel R and Hansen, Torben and Pedersen, Oluf and Jinga, Viorel and Neal, David E and Catalona, William J and Wrensch, Margaret and Wiencke, John and Jenkins, Robert B and Nagore, Eduardo and Vogel, Ulla and Kiemeney, Lambertus A and Kumar, Rajiv and Mayordomo, José I and Olafsson, Jon H and Kong, Augustine and ... and Swedish Low-risk Colorectal Cancer Study Group and Swedish Low-Risk Colorectal Canc
Nature genetics, ISSN 1546-1718, 2011, Volume 43, Issue 11, pp. 1098 - 1103
Journal Article
by Helgadottir, Anna and Gretarsdottir, Solveig and Thorleifsson, Gudmar and Holm, Hilma and Patel, Riyaz S and Gudnason, Thorarinn and Jones, Gregory T and van Rij, Andre M and Eapen, Danny J and Baas, Annette F and Tregouet, David-Alexandre and Morange, Pierre-Emmanuel and Emmerich, Joseph and Lindblad, Bengt and Gottsäter, Anders and Kiemeny, Lambertus A and Lindholt, Jes S and Sakalihasan, Natzi and Ferrell, Robert E and Carey, David J and Elmore, James R and Tsao, Philip S and Grarup, Niels and Jørgensen, Torben and Witte, Daniel R and Hansen, Torben and Pedersen, Oluf and Pola, Roberto and Gaetani, Eleonora and Magnadottir, Hulda B and Wijmenga, Cisca and Tromp, Gerard and Ronkainen, Antti and Ruigrok, Ynte M and Blankensteijn, Jan D and Mueller, Thomas and Wells, Philip S and Corral, Javier and Soria, Jose Manuel and Souto, Juan Carlos and Peden, John F and Jalilzadeh, Shapour and Mayosi, Bongani M and Keavney, Bernard and Strawbridge, Rona J and Sabater-Lleal, Maria and Gertow, Karl and Baldassarre, Damiano and Nyyssönen, Kristiina and Rauramaa, Rainer and Smit, Andries J and Mannarino, Elmo and Giral, Philippe and Tremoli, Elena and de Faire, Ulf and Humphries, Steve E and Hamsten, Anders and Haraldsdottir, Vilhelmina and Olafsson, Isleifur and Magnusson, Magnus K and Samani, Nilesh J and Levey, Allan I and Markus, Hugh S and Kostulas, Konstantinos and Dichgans, Martin and Berger, Klaus and Kuhlenbäumer, Gregor and Ringelstein, E. Bernd and Stoll, Monika and Seedorf, Udo and Rothwell, Peter M and Powell, Janet T and Kuivaniemi, Helena and Onundarson, Pall T and Valdimarsson, Einar and Matthiasson, Stefan E and Gudbjartsson, Daniel F and Thorgeirsson, Guðmundur and Quyyumi, Arshed A and Watkins, Hugh and Farrall, Martin and Thorsteinsdottir, Unnur and Stefansson, Kari
Journal of the American College of Cardiology, ISSN 0735-1097, 2012, Volume 60, Issue 8, pp. 722 - 729
Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene ( LPA ) on vascular diseases with different... 
Cardiovascular | Internal Medicine | atherosclerosis | genetic | association | thrombosis | lipoprotein(a) | INTIMA-MEDIA THICKNESS | RISK-FACTORS | METAANALYSIS | MYOCARDIAL-INFARCTION | UMCG Approved | VASCULAR-DISEASE | WOMEN | PERIPHERAL ARTERIAL-DISEASE | ISCHEMIC-STROKE | SEVERITY | CARDIAC & CARDIOVASCULAR SYSTEMS | Severity of Illness Index | Myocardial Infarction - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Apolipoproteins A - genetics | Angiography | Carotid Intima-Media Thickness | Intracranial Aneurysm - genetics | Atherosclerosis - genetics | Humans | Risk Factors | Brain Ischemia - genetics | African Americans - genetics | Linear Models | Logistic Models | Aortic Aneurysm, Abdominal - genetics | Stroke - genetics | Venous Thromboembolism - genetics | Peripheral Arterial Disease - genetics | Age of Onset | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Odds Ratio | Medical colleges | Neurosciences | Stock options | Genes | Aneurysms | Coronary heart disease | Biometry | Lipoprotein A | Anopheles | Atherosclerosis | Medical genetics | Genetic research | Genetic aspects | Diabetes | Thromboembolism | Cardiology | Public health | Dementia | Stroke | Medical imaging | Values | Cardiovascular disease | Apolipoproteins | Thrombosis | Studies | Confidence intervals | Coronary vessels | Blood pressure | Drug therapy | Age | Methods | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article