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life sciences & biomedicine (107) 107
science & technology (107) 107
humans (86) 86
pulmonary hypertension (62) 62
animals (59) 59
respiratory system (51) 51
male (47) 47
life sciences (46) 46
human health and pathology (39) 39
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cardiovascular system & cardiology (27) 27
cells, cultured (27) 27
pulmonary arterial hypertension (27) 27
adult (26) 26
cardiac & cardiovascular systems (26) 26
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hypertension, pulmonary - metabolism (22) 22
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hypertension, pulmonary - drug therapy (20) 20
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hypertension, pulmonary - pathology (19) 19
pulmonary hypertension. acute cor pulmonale. pulmonary embolism. pulmonary vascular diseases (19) 19
signal transduction (19) 19
[sdv.bc]life sciences [q-bio]/cellular biology (18) 18
endothelial cells (17) 17
familial primary pulmonary hypertension (17) 17
pulmonary artery (17) 17
research (17) 17
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hypertension (15) 15
pulmonary artery - pathology (15) 15
pulmonary vascular remodeling (15) 15
[sdv.mhep.psr]life sciences [q-bio]/human health and pathology/pulmonology and respiratory tract (14) 14
care and treatment (14) 14
[sdv.mhep.csc]life sciences [q-bio]/human health and pathology/cardiology and cardiovascular system (13) 13
aged (13) 13
inflammation (13) 13
pulmonary arteries (13) 13
risk factors (13) 13
vascular remodeling (13) 13
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hypertension, pulmonary - chemically induced (12) 12
human necessities (11) 11
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mesh: hypertension, pulmonary (11) 11
preparations for medical, dental, or toilet purposes (11) 11
pulmonary artery - physiopathology (11) 11
disease progression (10) 10
growth factors (10) 10
hypertension, pulmonary - etiology (10) 10
hypertension, pulmonary - genetics (10) 10
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diseases of the peripheral vessels. diseases of the vena cava. miscellaneous (7) 7
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1. Dendritic Cells in Pulmonary Hypertension: Foot Soldiers or Hidden Enemies?
by Guignabert, Christophe
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 11/2020, Volume 63, Issue 5, pp. 551 - 552
Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Hypertension, Pulmonary | Dendritic Cells | Military Personnel | Humans | Hypertension | Antigens | NF-κB protein | Dendritic cells | Cytokines | Autoantigens | Immunosurveillance | Adaptive immunity | Pulmonary hypertension | Hemopoiesis | Interleukin 6 | Antigen-presenting cells | Immune system
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2. Full Text Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
by Rabinovitch, Marlene and Guignabert, Christophe and Humbert, Marc and Nicolls, Mark R
Circulation research, ISSN 0009-7330, 06/2014, Volume 115, Issue 1, pp. 165 - 175
hypertension, pulmonary | leukotriene B4 | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Macrophages - physiology | Dendritic Cells - immunology | Humans | Chemokines - physiology | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - immunology | Immunity | Cytokines - physiology | Hypertension, Pulmonary - therapy | Inflammation - complications | Animals | Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - immunology | Biomarkers | Hypertension, Pulmonary - etiology | Hypertension, Pulmonary - pathology | Index Medicus | Tertiary lymphoid follicle | Elastase | Leukotriene B4 | Macrophage and macrophage migration inhibitory factor | Pulmonary hypertension
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3. Full Text Pulmonary endothelial cell and its importance in the pathogenesis of pulmonary hypertension
by Guignabert, Christophe
Reproductive toxicology (Elmsford, N.Y.), ISSN 0890-6238, 08/2015, Volume 56, pp. 6 - 7
Pulmonary hypertension | Endothelium
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4. Full Text Pathology and Pathobiology of Pulmonary Hypertension
by Guignabert, Christophe and Dorfmuller, Peter
Seminars in respiratory and critical care medicine, ISSN 1069-3424, 10/2013, Volume 34, Issue 5, pp. 551 - 559
cellular cross talk | BMPR2 | inflammation | pulmonary vascular remodeling | endothelial dysfunction | pulmonary arterial hypertension | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Genetic Predisposition to Disease | Lung - pathology | Endothelial Cells | Humans | Endothelium, Vascular - physiopathology | Hypertension, Pulmonary - physiopathology | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - genetics | Pulmonary Artery - physiopathology | Pulmonary Circulation - immunology | Muscle, Smooth, Vascular - pathology | Fibrosis | Endothelium, Vascular - pathology | Lung - blood supply | Hypertension, Pulmonary - pathology | Lung - immunology | Pulmonary Artery - pathology | Endothelium, Vascular - immunology | Inflammation - physiopathology | Pulmonary Artery - immunology | Index Medicus
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5. Full Text RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling
by Guilluy, Christophe and Eddahibi, Saadia and Agard, Christian and Guignabert, Christophe and Izikki, Mohamed and Tu, Ly and Savale, Laurent and Humbert, Marc and Fadel, Elie and Adnot, Serge and Loirand, Gervaise and Pacaud, Pierre
American journal of respiratory and critical care medicine, ISSN 1073-449X, 06/2009, Volume 179, Issue 12, pp. 1151 - 1158
Signal transduction | Serotonin | Rho proteins | Muscle, smooth | Hypertension, pulmonary | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Pneumology | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Humans | Middle Aged | Hypertension, Pulmonary - physiopathology | Male | rhoA GTP-Binding Protein - metabolism | Young Adult | Vasoconstriction - physiology | Pulmonary Artery - metabolism | rho-Associated Kinases - metabolism | Adult | Female | Hypertension, Pulmonary - enzymology | Disease Models, Animal | Cells, Cultured | Mice, Transgenic | Blotting, Western | Muscle, Smooth, Vascular - pathology | Animals | Blood Platelets - metabolism | Serotonin - metabolism | Adolescent | Signal Transduction - physiology | Mice | Enzyme Activation | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Index Medicus | Abridged Index Medicus
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6. Full Text Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension
by Tuder, Rubin M., MD and Archer, Stephen L., MD and Dorfmüller, Peter, MD, PhD and Erzurum, Serpil C., MD and Guignabert, Christophe, PhD and Michelakis, Evangelos, MD and Rabinovitch, Marlene, MD and Schermuly, Ralph, PhD and Stenmark, Kurt R., MD and Morrell, Nicholas W., MD
Journal of the American College of Cardiology, ISSN 0735-1097, 2013, Volume 62, Issue 25, pp. D4 - D12
Cardiovascular | Internal Medicine | pulmonary arteries | metabolism | inflammation | pulmonary veins | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Muscle, Smooth, Vascular - pathology | Pulmonary Artery - metabolism | Pulmonary Veins - pathology | Animals | Muscle, Smooth, Vascular - metabolism | Humans | Signal Transduction - physiology | Hypertension, Pulmonary - metabolism | Hypertension, Pulmonary - pathology | Pulmonary Veins - metabolism | Pulmonary Artery - pathology | Physiological aspects | Bone morphogenetic proteins | Superoxide | Pulmonary hypertension | Index Medicus | Abridged Index Medicus
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7. Full Text Translating research into improved patient care in pulmonary arterial hypertension
by Bonnet, Sébastien and Provencher, Steeve and Guignabert, Christophe and Perros, Frédéric and Boucherat, Olivier and Schermuly, Ralph Theo and Hassoun, Paul M and Rabinovitch, Marlene and Nicolls, Mark R and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 03/2017, Volume 195, Issue 5, pp. 583 - 595
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biomedical Research | Disease Management | Patient Care - standards | Quality Improvement | Humans | Hypertension, Pulmonary - therapy | Index Medicus | Abridged Index Medicus | Pulmonary
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8. Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
by Huertas, Alice and Montani, David and Savale, Laurent and Pichon, Jeremie and Tu, Ly and Parent, Florence and Guignabert, Christophe and Humbert, Marc
The European respiratory journal, ISSN 0903-1936, 07/2020, Volume 56, Issue 1
Life Sciences & Biomedicine | Respiratory System | Science & Technology | COVID-19 | Coronavirus Infections | Intensive Care Units | SARS-CoV-2 | Endothelial Cells | Pandemics | Venous Thromboembolism | Pneumonia, Viral - epidemiology | Humans | Betacoronavirus
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9. Full Text Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension
by Tamura, Yuichi and Phan, Carole and Tu, Ly and Le Hiress, Morane and Thuillet, Raphaël and Jutant, Etienne-Marie and Fadel, Elie and Savale, Laurent and Huertas, Alice and Humbert, Marc and Guignabert, Christophe
The Journal of clinical investigation, ISSN 0021-9738, 05/2018, Volume 128, Issue 5, pp. 1956 - 1970
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Familial Primary Pulmonary Hypertension - pathology | Up-Regulation | Vascular Remodeling | Muscle, Smooth, Vascular - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Rats | Familial Primary Pulmonary Hypertension - genetics | Mice, Transgenic | Pulmonary Artery - physiopathology | Signal Transduction - genetics | Muscle, Smooth, Vascular - physiopathology | Familial Primary Pulmonary Hypertension - metabolism | Familial Primary Pulmonary Hypertension - physiopathology | Arterioles - pathology | Muscle, Smooth, Vascular - pathology | Pulmonary Artery - metabolism | Animals | Arterioles - metabolism | Arterioles - physiopathology | Cytokine Receptor gp130 - biosynthesis | Mice | Myocytes, Smooth Muscle - metabolism | Pulmonary Artery - pathology | Care and treatment | Cytokine receptors | Physiological aspects | Development and progression | Health aspects | Pulmonary artery | Pulmonary hypertension | Interleukin-6 | Cytochrome | Hypertension | Animal models | Cytokines | Arterioles | Pathogenesis | Pulmonary arteries | Smooth muscle | Cardiovascular disease | Interleukin 6 | Proteins | Signal transduction | Interleukin 6 receptors | Rodents | Medical prognosis | Hypoxia | Heart diseases | Growth factors | Glycoprotein gp130 | Veins & arteries | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cellular Biology | Cardiology and cardiovascular system | Pulmonology and respiratory tract
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10. Full Text Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension
by Guignabert, Christophe and Phan, Carole and Seferian, Andrei and Huertas, Alice and Tu, Ly and Thuillet, Raphaël and Sattler, Caroline and Hiress, Morane Le and Tamura, Yuichi and Jutant, Etienne-Marie and Chaumais, Marie-Camille and Bouchet, Stéphane and Manéglier, Benjamin and Molimard, Mathieu and Rousselot, Philippe and Sitbon, Olivier and Simonneau, Gérald and Montani, David and Humbert, Marc
The Journal of clinical investigation, ISSN 0021-9738, 09/2016, Volume 126, Issue 9, pp. 3207 - 3218
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | E-Selectin - blood | Male | Hypertension, Pulmonary - chemically induced | Hypoxia - metabolism | Antineoplastic Agents - adverse effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Adult | Female | Intercellular Adhesion Molecule-1 - blood | Antineoplastic Agents - pharmacology | Genetic Predisposition to Disease | Imatinib Mesylate - pharmacology | Cells, Cultured | Rats | Mitochondria - metabolism | Vascular Cell Adhesion Molecule-1 - blood | Dasatinib - pharmacology | Animals | Lung - drug effects | Dasatinib - adverse effects | Hemodynamics | Lung - blood supply | Apoptosis | Dasatinib | Research | Health aspects | Pulmonary hypertension | Risk factors | Scholarships & fellowships | Toxicity | Mortality | Rodents | Leukemia | Hypoxia | Grants | Laboratory animals | Experiments | Drug dosages | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cellular Biology | Cardiology and cardiovascular system | Pulmonology and respiratory tract
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